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Biostatistics and Computational Biology

URMC / Department of Biostatistics and Computational Biology / People & Research / Faculty / Michael B. Sohn, PhD

Michael B. Sohn, PhD

Assistant Professor
Ph.D. (2015) University of ArizonaMichael Sohn Photograph

Contact Information

University of Rochester
Dept of Biostatistics and Computational Biology
265 Crittenden Boulevard, CU 420630 
Rochester, New York 14642-0630
 
Office: Saunders Research Building 4219
Phone: (585) 276-6092
Fax: (585) 273-1031
Email: Michael_Sohn@urmc.rochester.edu

Research Interests

  • High-Dimensional Data Analysis
  • Compositional Data Analysis
  • Statistical Machine Learning
  • Causal Mediation Analysis
  • Genomics and Metagenomics

Selected Publications

  • Madere, F.S., Sohn, M.B., Winbush, A.K., Barr, B., Grier, A., Palumbo, C., Java, J., Meiring, T., Williamson, A., Bekker, L., Adler, D.H., and Monaco, C.L. (2022). Transkingdom Analysis of the Female Reproductive Tract Reveals Bacteriophages form Communities. Viruses, 14(2): 430.

  • Loh, K.P., Sanapala, C., Janelsins, M., Klepin, H., Schnall, R., Culakova, E., Sohn, M.B., Vertino, P., Susiarjo, M., Jensen-Battaglia, M., Becker, M.W., Liesveld, J., Mendler, J.H., Huselton, E., Lin, P.J., Mustian, K. (2021). Protocol for a pilot randomized controlled trial of a mobile health exercise intervention for older patients with myeloid neoplasms (GO-EXCAP 2). J Geriatr Oncol, doi: 10.1016/j.jgo.2021.12.011.

  • Sohn, M.B., Lu, J., and Li, H. (2021). A Compositional Mediation Model for Binary Outcome: Application to Microbiome Studies. Bioinformatics, 38(1):16-21.

  • Wu, T.T., Xiao, J., Sohn, M.B., Fiscella, K.A., Gilbert, C., Grier, A., Gill, A.L, and Gill, S.R. (2021). Machine Learning Approach Identified Multi-Platform Factors for Caries Prediction in Child-Mother Dyads. Front Cell Infect Microbiol, doi: 10.3389/fcimb.2021.727630.

  • Johnson, W.L., Sohn, M.B., Taffner, S., Chatterjee, P., Dunman, P.M., Pecora, N., and Wozniak, R.A.F. (2021). Genomics of Staphylococcus aureus ocular isolates. PLoS ONE, 16(5): e0250975.

  • Raj, D.S., Sohn, M.B., Charytan, D.M., Himmelfarb, J., Ikizler, T.A., Mehrotra, R., Ramezani, A., Regunathan-Shenk, R., Hsu, J.Y., Landis, J.R., Li, H., Kimmel, P.L., Kliger, A.S., and Dember, L.M. (2021). The Microbiome and p-Inulin in Hemodialysis: A Feasibility Study. Kidney360, 2(3):445-455.

  • Gibson, J.S., Ridner, S.H., Dietrich, M., Sohn, M.B., Rhoten, B.A., and Claassen, D.O. (2021). Measuring Functional Status in Huntington’s Disease. Mov Disord, 36(3):757-761.

  • Laskey, E., Chen, Y., Gruber, E., Sohn, M.B., Chojnacki, M., and Wozniak, R.A.F. (2020). Efficacy of a novel ophthalmic antimicrobial drug combination towards a large panel of Staphylococcus aureus clinical ocular isolates from around the world. Cornea, 39(10):1278-1284.

  • Simon-Soro, A., Sohn, M.B., McGinniss, J.E., Imai, I., Brown, M.C., Knecht, V.R., Bailey, A., Clarke, E.L., Cantu, E., Li. H2., Bittinger, K., Diamond, J.M., Christie, J.D., Bushman, F.D., and Collman, R.G. (2019). Upper Respiratory Dysbiosis with a Facultative-Dominated Ecotype in Advanced Lung Disease and Dynamic Change after Lung Transplant. Ann Am Thorac Soc. doi: 10.1513/AnnalsATS.201904-299OC.

  • McGinniss, J.E., Imai, I., Simon-Soro, A., Brown, M.C., Knecht, V.R., Frye, L., Ravindran, P., Wadell, D., Sohn, M.B., Li, H., Haas, A.R., Lanfranco, A., DiBardino, D.M., Bushman, F.D., and Collman, R.G. (2019). Molecular analysis of the endobronchial stent microbial biofilm reveals bacterial communities that associate with stent material and frequent fungal constituents. PLOS ONE, 14(5):e0217306.

  • Sohn, M.B. and Li, H. (2019). Compositional Mediation Analysis for Microbiome Studies. Annals of Applied Statistics, 13(1), 661-681.

  • Sohn, M.B. and Li, H. (2018).  A GLM‐based latent variable ordination method for microbiome samples.  Biometrics, 74: 448-457. 

  • Sohn, M.B., Du, R. and An, L. (2015).  A robust approach for identifying differentially abundant features in metagenomic samples.  Bioinformatics, 31(14), 2269-2275.

  • Pookhao, N., Sohn, M.B., Li, Q., Jenkins, I., Du, R., Jiang, H. and An, L. (2015).  A two-stage statistical procedure for feature selection and comparison in functional analysis of metagenomes, Bioinformatics, 31(2): 158-165.
  • Sohn, M.B., An, L., Pookhao, N. and Li, Q. (2014).  Accurate Genome Relative Abundance Estimation for Closely Related Species in a Metagenomic Sample, BMC Bioinformatics, 15:242.

Last updated: March 17, 2022