URMC / Cardiovascular Research Institute / Research / Jin Lab / Publications Recent Publications Wang JLuo JRotili DMai ASteegborn CXu SJin ZG SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells.; Inflammation. 2023 Jan 11. Zhang SKim JYXu SLiu HYin MKoroleva MGuo JPei XJin ZG Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ.; Proceedings of the National Academy of Sciences of the United States of America; Vol 117(9). 2020 Mar 03. Luo JJin FQYin MJin ZG Regulation of SRF protein stability by an autophagy-dependent pathway.; Biochemical and biophysical research communications; Vol 521(2). 2020 Jan 08. Xu SXu YLiu PZhang SLiu HSlavin SKumar SKoroleva MLuo JWu XRahman APelisek JJo HSi SMiller CLJin ZG The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.; European heart journal; Vol 40(29). 2019 Aug 01. Xu SJin ZG Hutchinson-Gilford Progeria Syndrome: Cardiovascular Pathologies and Potential Therapies.; Trends in biochemical sciences; Vol 44(7). 2019 Jul. Liu HZhang SXu SKoroleva MSmall EMJin ZG Myofibroblast-specific YY1 promotes liver fibrosis.; Biochemical and biophysical research communications; Vol 514(3). 2019 Jun 30. Xu SKamato DLittle PJNakagawa SPelisek JJin ZG Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics.; Pharmacology & therapeutics; Vol 196. 2019 Apr. Niu NXu SXu YLittle PJJin ZG Targeting Mechanosensitive Transcription Factors in Atherosclerosis.; Trends in pharmacological sciences; Vol 40(4). 2019 Apr. Lyu QXu SLyu YChoi MChristie CKSlivano OJRahman AJin ZGLong XXu YMiano JM SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4.; Proceedings of the National Academy of Sciences of the United States of America; Vol 116(2). 2019 Jan 08. Zhao FAnderson CKarnes SZhou QMa JJin ZGBhattacharjee PSWang S Expression, regulation and function of miR-126 in the mouse choroid vasculature.; Experimental eye research; Vol 170. 2018 May. Xu SPelisek JJin ZG Atherosclerosis Is an Epigenetic Disease.; Trends in endocrinology and metabolism: TEM; Vol 29(11). 2018 Jan. Xu SXu YYin MZhang SLiu PKoroleva MSi SLittle PJPelisek JJin ZG Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects.; Theranostics; Vol 8(11). 2018. Xu YXu SLiu PKoroleva MZhang SSi SJin ZG Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis.; Journal of the American Heart Association; Vol 6(12). 2017 Nov 30. Xu YLiu PXu SKoroleva MZhang SSi SJin ZG Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells.; Scientific reports; Vol 7(1). 2017 Jul 27. Halim DWilson MPOliver DBrosens EVerheij JBHan YNanda VLyu QDoukas MStoop HBrouwer RWvan IJcken WFSlivano OJBurns AJChristie CKde Mesy Bentley KLBrooks ASTibboel DXu SJin ZGDjuwantono TYan WAlves MMHofstra RMMiano JM Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.; Proceedings of the National Academy of Sciences of the United States of America; Vol 114(13). 2017 Mar 28. Deng HFung GQiu YWang CZhang JJin ZGLuo H Cleavage of Grb2-Associated Binding Protein 2 by Viral Proteinase 2A during Coxsackievirus Infection.; Frontiers in cellular and infection microbiology; Vol 7. 2017. Xu SLiu BYin MKoroleva MMastrangelo MTure SMorrell CNZhang DXFisher EAJin ZG A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.; Oncotarget; Vol 7(25). 2016 Jun 21. Xu SYin MKoroleva MMastrangelo MAZhang WBai PLittle PJJin ZG SIRT6 protects against endothelial dysfunction and atherosclerosis in mice.; Aging; Vol 8(5). 2016 May. Xu SHa CHWang WXu XYin MJin FQMastrangelo MKoroleva MFujiwara KJin ZG PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling.; Cellular signalling; Vol 28(3). 2016 Mar. Xu SBai PJin ZG Sirtuins in Cardiovascular Health and Diseases.; Trends in endocrinology and metabolism: TEM; Vol 27(10). 2016 Jan. Xu SKoroleva MYin MJin ZG Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells.; Translational research : the journal of laboratory and clinical medicine; Vol 176. 2016 Jan. Liu ZXu SHuang XWang JGao SLi HZhou CYe JChen SJin ZGLiu P Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1).; British journal of pharmacology; Vol 172(23). 2015 Dec. Deng HFung GShi JXu SWang CYin MHou JZhang JJin ZGLuo H Enhanced enteroviral infectivity via viral protease-mediated cleavage of Grb2-associated binder 1.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 29(11). 2015 Nov. Wang WXu SYin MJin ZG Essential roles of Gab1 tyrosine phosphorylation in growth factor-mediated signaling and angiogenesis.; International journal of cardiology; Vol 181. 2015 Feb 15. Kwon ISWang WXu SJin ZG Histone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium.; Cardiovascular research; Vol 104(1). 2014 Oct 01. Jhun BSO-Uchi JWang WHa CHZhao JKim JYWong CDirksen RTLopes CMJin ZG Adrenergic signaling controls RGK-dependent trafficking of cardiac voltage-gated L-type Ca2+ channels through PKD1.; Circulation research; Vol 110(1). 2012 Jan 6. Zhao JWang WHa CHKim JYWong CRedmond EMHamik AJain MKFeng GSJin ZG Endothelial Grb2-associated binder 1 is crucial for postnatal angiogenesis.; Arteriosclerosis, thrombosis, and vascular biology; Vol 31(5). 2011 May. Ha CHKim JYZhao JWang WJhun BSWong CJin ZG PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy.; Proceedings of the National Academy of Sciences of the United States of America; Vol 107(35). 2010 Aug 31. Edirisinghe IArunachalam GWong CYao HRahman APhipps RPJin ZGRahman I Cigarette-smoke-induced oxidative/nitrosative stress impairs VEGF- and fluid-shear-stress-mediated signaling in endothelial cells.; Antioxidants & redox signaling; Vol 12(12). 2010 Jun 15. Wang WHa CHJhun BSWong CJain MKJin ZG Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS.; Blood; Vol 115(14). 2010 Apr 08. Ha CHJin ZG Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis.; Molecules and cells; Vol 28(1). 2009 Jul 31. Ha CHJhun BSKao HYJin ZG VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis.; Arteriosclerosis, thrombosis, and vascular biology; Vol 28(10). 2008 Oct. Xu XJhun BSHa CHJin ZG Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation.; Endocrinology; Vol 149(8). 2008 Aug. Edirisinghe IYang SRYao HRajendrasozhan SCaito SAdenuga DWong CRahman APhipps RPJin ZGRahman I VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 22(7). 2008 Jul. Satoh KMatoba TSuzuki JO'Dell MRNigro PCui ZMohan APan SLi LJin ZGYan CAbe JBerk BC Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation.; Circulation; Vol 117(24). 2008 Jun 17. Ha CHWang WJhun BSWong CHausser APfizenmaier KMcKinsey TAOlson ENJin ZG Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis.; The Journal of biological chemistry; Vol 283(21). 2008 May 23. Zhang QGuo RLu YZhao LZhou QSchwarz EMHuang JChen DJin ZGBoyce BFXing L VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism.; The Journal of biological chemistry; Vol 283(19). 2008 May 9. Ha CHBennett AMJin ZG A novel role of vascular endothelial cadherin in modulating c-Src activation and downstream signaling of vascular endothelial growth factor.; The Journal of biological chemistry; Vol 283(11). 2008 Mar 14. Ha CHJhun BSKao HYJin ZG "VEGF Stimulates HDAC7 Phosphorylation and Cytoplasmic Accumulation Modulating Matrix Metalloproteinase Expression and Angiongenesis."; Arterioscler Thromb Vasc Biol.. 2008 Jan 01. Xu XHa CHWong CWang WHausser APfizenmaier KOlson ENMcKinsey TAJin ZG Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy.; Arteriosclerosis, thrombosis, and vascular biology; Vol 27(11). 2007 Nov. Suzuki JJin ZGMeoli DFMatoba TBerk BC Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells.; Circulation research; Vol 98(6). 2006 Mar 31.