URMC / Cardiovascular Research Institute / Research / Jin Lab / Publications

Recent Publications

1. Wang J
2. Luo J
3. Rotili D
4. Mai A
5. Steegborn C
6. Xu S
7. Jin ZG
SIRT6 Protects Against Lipopolysaccharide-Induced Inflammation in Human Pulmonary Lung Microvascular Endothelial Cells.; Inflammation. 2023 Jan 11.
1. Zhang S
2. Kim JY
3. Xu S
4. Liu H
5. Yin M
6. Koroleva M
7. Guo J
8. Pei X
9. Jin ZG
Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ.; Proceedings of the National Academy of Sciences of the United States of America; Vol 117(9). 2020 Mar 03.
1. Luo J
2. Jin FQ
3. Yin M
4. Jin ZG
Regulation of SRF protein stability by an autophagy-dependent pathway.; Biochemical and biophysical research communications; Vol 521(2). 2020 Jan 08.
1. Xu S
2. Xu Y
3. Liu P
4. Zhang S
5. Liu H
6. Slavin S
7. Kumar S
8. Koroleva M
9. Luo J
10. Wu X
11. Rahman A
12. Pelisek J
13. Jo H
14. Si S
15. Miller CL
16. Jin ZG
The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.; European heart journal; Vol 40(29). 2019 Aug 01.
1. Xu S
2. Jin ZG
Hutchinson-Gilford Progeria Syndrome: Cardiovascular Pathologies and Potential Therapies.; Trends in biochemical sciences; Vol 44(7). 2019 Jul.
1. Liu H
2. Zhang S
3. Xu S
4. Koroleva M
5. Small EM
6. Jin ZG
Myofibroblast-specific YY1 promotes liver fibrosis.; Biochemical and biophysical research communications; Vol 514(3). 2019 Jun 30.
1. Xu S
2. Kamato D
3. Little PJ
4. Nakagawa S
5. Pelisek J
6. Jin ZG
Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics.; Pharmacology & therapeutics; Vol 196. 2019 Apr.
1. Niu N
2. Xu S
3. Xu Y
4. Little PJ
5. Jin ZG
Targeting Mechanosensitive Transcription Factors in Atherosclerosis.; Trends in pharmacological sciences; Vol 40(4). 2019 Apr.
1. Lyu Q
2. Xu S
3. Lyu Y
4. Choi M
5. Christie CK
6. Slivano OJ
7. Rahman A
8. Jin ZG
9. Long X
10. Xu Y
11. Miano JM
SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4.; Proceedings of the National Academy of Sciences of the United States of America; Vol 116(2). 2019 Jan 08.
1. Zhao F
2. Anderson C
3. Karnes S
4. Zhou Q
5. Ma J
6. Jin ZG
7. Bhattacharjee PS
8. Wang S
Expression, regulation and function of miR-126 in the mouse choroid vasculature.; Experimental eye research; Vol 170. 2018 May.
1. Xu S
2. Pelisek J
3. Jin ZG
Atherosclerosis Is an Epigenetic Disease.; Trends in endocrinology and metabolism: TEM; Vol 29(11). 2018 Jan.
1. Xu S
2. Xu Y
3. Yin M
4. Zhang S
5. Liu P
6. Koroleva M
7. Si S
8. Little PJ
9. Pelisek J
10. Jin ZG
Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects.; Theranostics; Vol 8(11). 2018.
1. Xu Y
2. Xu S
3. Liu P
4. Koroleva M
5. Zhang S
6. Si S
7. Jin ZG
Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis.; Journal of the American Heart Association; Vol 6(12). 2017 Nov 30.
1. Xu Y
2. Liu P
3. Xu S
4. Koroleva M
5. Zhang S
6. Si S
7. Jin ZG
Tannic acid as a plant-derived polyphenol exerts vasoprotection via enhancing KLF2 expression in endothelial cells.; Scientific reports; Vol 7(1). 2017 Jul 27.
1. Halim D
2. Wilson MP
3. Oliver D
4. Brosens E
5. Verheij JB
6. Han Y
7. Nanda V
8. Lyu Q
9. Doukas M
10. Stoop H
11. Brouwer RW
12. van IJcken WF
13. Slivano OJ
14. Burns AJ
15. Christie CK
16. de Mesy Bentley KL
17. Brooks AS
18. Tibboel D
19. Xu S
20. Jin ZG
21. Djuwantono T
22. Yan W
23. Alves MM
24. Hofstra RM
25. Miano JM
Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.; Proceedings of the National Academy of Sciences of the United States of America; Vol 114(13). 2017 Mar 28.
1. Deng H
2. Fung G
3. Qiu Y
4. Wang C
5. Zhang J
6. Jin ZG
7. Luo H
Cleavage of Grb2-Associated Binding Protein 2 by Viral Proteinase 2A during Coxsackievirus Infection.; Frontiers in cellular and infection microbiology; Vol 7. 2017.
1. Xu S
2. Liu B
3. Yin M
4. Koroleva M
5. Mastrangelo M
6. Ture S
7. Morrell CN
8. Zhang DX
9. Fisher EA
10. Jin ZG
A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.; Oncotarget; Vol 7(25). 2016 Jun 21.
1. Xu S
2. Yin M
3. Koroleva M
4. Mastrangelo MA
5. Zhang W
6. Bai P
7. Little PJ
8. Jin ZG
SIRT6 protects against endothelial dysfunction and atherosclerosis in mice.; Aging; Vol 8(5). 2016 May.
1. Xu S
2. Ha CH
3. Wang W
4. Xu X
5. Yin M
6. Jin FQ
7. Mastrangelo M
8. Koroleva M
9. Fujiwara K
10. Jin ZG
PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling.; Cellular signalling; Vol 28(3). 2016 Mar.
1. Xu S
2. Bai P
3. Jin ZG
Sirtuins in Cardiovascular Health and Diseases.; Trends in endocrinology and metabolism: TEM; Vol 27(10). 2016 Jan.
1. Xu S
2. Koroleva M
3. Yin M
4. Jin ZG
Atheroprotective laminar flow inhibits Hippo pathway effector YAP in endothelial cells.; Translational research : the journal of laboratory and clinical medicine; Vol 176. 2016 Jan.
1. Liu Z
2. Xu S
3. Huang X
4. Wang J
5. Gao S
6. Li H
7. Zhou C
8. Ye J
9. Chen S
10. Jin ZG
11. Liu P
Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1).; British journal of pharmacology; Vol 172(23). 2015 Dec.
1. Deng H
2. Fung G
3. Shi J
4. Xu S
5. Wang C
6. Yin M
7. Hou J
8. Zhang J
9. Jin ZG
10. Luo H
Enhanced enteroviral infectivity via viral protease-mediated cleavage of Grb2-associated binder 1.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 29(11). 2015 Nov.
1. Wang W
2. Xu S
3. Yin M
4. Jin ZG
Essential roles of Gab1 tyrosine phosphorylation in growth factor-mediated signaling and angiogenesis.; International journal of cardiology; Vol 181. 2015 Feb 15.
1. Kwon IS
2. Wang W
3. Xu S
4. Jin ZG
Histone deacetylase 5 interacts with Krüppel-like factor 2 and inhibits its transcriptional activity in endothelium.; Cardiovascular research; Vol 104(1). 2014 Oct 01.
1. Jhun BS
2. O-Uchi J
3. Wang W
4. Ha CH
5. Zhao J
6. Kim JY
7. Wong C
8. Dirksen RT
9. Lopes CM
10. Jin ZG
Adrenergic signaling controls RGK-dependent trafficking of cardiac voltage-gated L-type Ca2+ channels through PKD1.; Circulation research; Vol 110(1). 2012 Jan 6.
1. Zhao J
2. Wang W
3. Ha CH
4. Kim JY
5. Wong C
6. Redmond EM
7. Hamik A
8. Jain MK
9. Feng GS
10. Jin ZG
Endothelial Grb2-associated binder 1 is crucial for postnatal angiogenesis.; Arteriosclerosis, thrombosis, and vascular biology; Vol 31(5). 2011 May.
1. Ha CH
2. Kim JY
3. Zhao J
4. Wang W
5. Jhun BS
6. Wong C
7. Jin ZG
PKA phosphorylates histone deacetylase 5 and prevents its nuclear export, leading to the inhibition of gene transcription and cardiomyocyte hypertrophy.; Proceedings of the National Academy of Sciences of the United States of America; Vol 107(35). 2010 Aug 31.
1. Edirisinghe I
2. Arunachalam G
3. Wong C
4. Yao H
5. Rahman A
6. Phipps RP
7. Jin ZG
8. Rahman I
Cigarette-smoke-induced oxidative/nitrosative stress impairs VEGF- and fluid-shear-stress-mediated signaling in endothelial cells.; Antioxidants & redox signaling; Vol 12(12). 2010 Jun 15.
1. Wang W
2. Ha CH
3. Jhun BS
4. Wong C
5. Jain MK
6. Jin ZG
Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS.; Blood; Vol 115(14). 2010 Apr 08.
1. Ha CH
2. Jin ZG
Protein kinase D1, a new molecular player in VEGF signaling and angiogenesis.; Molecules and cells; Vol 28(1). 2009 Jul 31.
1. Ha CH
2. Jhun BS
3. Kao HY
4. Jin ZG
VEGF stimulates HDAC7 phosphorylation and cytoplasmic accumulation modulating matrix metalloproteinase expression and angiogenesis.; Arteriosclerosis, thrombosis, and vascular biology; Vol 28(10). 2008 Oct.
1. Xu X
2. Jhun BS
3. Ha CH
4. Jin ZG
Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation.; Endocrinology; Vol 149(8). 2008 Aug.
1. Edirisinghe I
2. Yang SR
3. Yao H
4. Rajendrasozhan S
5. Caito S
6. Adenuga D
7. Wong C
8. Rahman A
9. Phipps RP
10. Jin ZG
11. Rahman I
VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 22(7). 2008 Jul.
1. Satoh K
2. Matoba T
3. Suzuki J
4. O'Dell MR
5. Nigro P
6. Cui Z
7. Mohan A
8. Pan S
9. Li L
10. Jin ZG
11. Yan C
12. Abe J
13. Berk BC
Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation.; Circulation; Vol 117(24). 2008 Jun 17.
1. Ha CH
2. Wang W
3. Jhun BS
4. Wong C
5. Hausser A
6. Pfizenmaier K
7. McKinsey TA
8. Olson EN
9. Jin ZG
Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis.; The Journal of biological chemistry; Vol 283(21). 2008 May 23.
1. Zhang Q
2. Guo R
3. Lu Y
4. Zhao L
5. Zhou Q
6. Schwarz EM
7. Huang J
8. Chen D
9. Jin ZG
10. Boyce BF
11. Xing L
VEGF-C, a lymphatic growth factor, is a RANKL target gene in osteoclasts that enhances osteoclastic bone resorption through an autocrine mechanism.; The Journal of biological chemistry; Vol 283(19). 2008 May 9.
1. Ha CH
2. Bennett AM
3. Jin ZG
A novel role of vascular endothelial cadherin in modulating c-Src activation and downstream signaling of vascular endothelial growth factor.; The Journal of biological chemistry; Vol 283(11). 2008 Mar 14.
1. Ha CH
2. Jhun BS
3. Kao HY
4. Jin ZG
"VEGF Stimulates HDAC7 Phosphorylation and Cytoplasmic Accumulation Modulating Matrix Metalloproteinase Expression and Angiongenesis."; Arterioscler Thromb Vasc Biol.. 2008 Jan 01.
1. Xu X
2. Ha CH
3. Wong C
4. Wang W
5. Hausser A
6. Pfizenmaier K
7. Olson EN
8. McKinsey TA
9. Jin ZG
Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy.; Arteriosclerosis, thrombosis, and vascular biology; Vol 27(11). 2007 Nov.
1. Suzuki J
2. Jin ZG
3. Meoli DF
4. Matoba T
5. Berk BC
Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells.; Circulation research; Vol 98(6). 2006 Mar 31.