Recent Publications

• 1. Liang C
  2. Malik S
  3. He M
  4. Groom L
  5. Ture SK
  6. O'Connor TN
  7. Morrell CN
  8. Dirksen RT
  Compound heterozygous RYR1-RM mouse model reveals disease pathomechanisms and muscle adaptations to promote postnatal survival.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 38(20), pp. e70120. 2024 Oct.
• 1. Li C
  2. Ture SK
  3. Nieves-Lopez B
  4. Blick-Nitko SK
  5. Maurya P
  6. Livada AC
  7. Stahl TJ
  8. Kim M
  9. Pietropaoli AP
  10. Morrell CN
  Thrombocytopenia Independently Leads to Changes in Monocyte Immune Function.; Circulation research. 2024 Mar 08.
• 1. Akkipeddi SMK
  2. Rahmani R
  3. Schartz D
  4. Chittaranjan S
  5. Ellens NR
  6. Kohli GS
  7. Bhalla T
  8. Mattingly TK
  9. Welle K
  10. Morrell CN
  11. Bender MT
  Stroke emboli from patients with atrial fibrillation enriched with neutrophil extracellular traps.; Research and practice in thrombosis and haemostasis; Vol 8(2), pp. 102347. 2024 Feb 15.
• 1. Li C
  2. Morrell CN
  Commentary on "Desialylated Platelets Maintain Immune Quiescence through Regulating Kupffer Cells".; Research (Washington, D.C.); Vol 6, pp. 0279. 2023 Dec 12.
• 1. O'Reilly D
  2. Murphy CA
  3. Moore CM
  4. Ní Áinle F
  5. Gormley IC
  6. Morrell CN
  7. Curley A
  8. Mc Callion N
  9. Maguire P
  Markers of platelet activation foR identification of late onset sEpsis in infaNTs: PARENT study protocol.; Pediatric research; Vol 95(3), pp. 852-856. 2023 Sep 27.
• 1. Maurya P
  2. Ture SK
  3. Li C
  4. Scheible KM
  5. McGrath KE
  6. Palis J
  7. Morrell CN
  Transfusion of Adult, but Not Neonatal, Platelets Promotes Monocyte Trafficking in Neonatal Mice.; Arteriosclerosis, thrombosis, and vascular biology. 2023 Mar 23.
• 1. Livada AC
  2. Pariser DN
  3. Morrell CN
  Megakaryocytes in the lung: History and future perspectives.; Research and practice in thrombosis and haemostasis; Vol 7(2), pp. 100053. 2023 Jan 19.
• 1. Morrell CN
  2. Mix D
  3. Aggarwal A
  4. Bhandari R
  5. Godwin M
  6. Owens Iii AP
  7. Lyden SP
  8. Doyle A
  9. Krauel K
  10. Rondina MT
  11. Mohan A
  12. Lowenstein CJ
  13. Shim S
  14. Stauffer S
  15. Josyula VP
  16. Ture SK
  17. Yule DI
  18. Wagner Iii LE
  19. Ashton JM
  20. Elbadawi A
  21. Cameron SJ
  Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms.; The Journal of clinical investigation. 2022 Mar 24.
• 1. Hilt ZT
  2. Ture SK
  3. Mohan A
  4. Arne A
  5. Morrell CN
  Platelet-derived β2m regulates age related monocyte/macrophage functions.; Aging; Vol 11. 2019 Dec 18.
• 1. Morrell CN
  2. Hilt ZT
  3. Pariser DN
  4. Maurya P
  PAD4 and von Willebrand Factor Link Inflammation and Thrombosis.; Circulation research; Vol 125(5). 2019 Aug 16.
• 1. Dugbartey GJ
  2. Quinn B
  3. Luo L
  4. Mickelsen DM
  5. Ture SK
  6. Morrell CN
  7. Czyzyk J
  8. Doyley MM
  9. Yan C
  10. Berk BC
  11. Korshunov VA
  The Protective Role of Natriuretic Peptide Receptor 2 against High Salt Injury in the Renal Papilla.; The American journal of pathology. 2019 Jun 17.
• 1. Bennett JA
  2. Ture SK
  3. Schmidt RA
  4. Mastrangelo MA
  5. Cameron SJ
  6. Terry LE
  7. Yule DI
  8. Morrell CN
  9. Lowenstein CJ
  Acetylcholine inhibits platelet activation.; The Journal of pharmacology and experimental therapeutics. 2019 Feb 14.
• 1. Hilt ZT
  2. Pariser DN
  3. Ture SK
  4. Mohan A
  5. Quijada P
  6. Asante A
  7. Cameron SJ
  8. Sterling JA
  9. Merkel AR
  10. Johanson AL
  11. Jenkins JL
  12. Small EM
  13. McGrath KE
  14. Palis J
  15. Elliott MR
  16. Morrell CN
  Platelet-derived β2M regulates monocyte inflammatory responses.; JCI insight. 2019 Jan 31.
• 1. Morrell CN
  2. Pariser DN
  3. Hilt ZT
  4. Vega Ocasio D
  The Platelet Napoleon Complex-Small Cells, but Big Immune Regulatory Functions.; Annual review of immunology. 2018 Nov 28.
• 1. Cameron SJ
  2. Mix DS
  3. Ture SK
  4. Schmidt RA
  5. Mohan A
  6. Pariser D
  7. Stoner MC
  8. Shah P
  9. Chen L
  10. Zhang H
  11. Field DJ
  12. Modjeski KL
  13. Toth S
  14. Morrell CN
  Hypoxia and Ischemia Promote a Maladaptive Platelet Phenotype.; Arteriosclerosis, thrombosis, and vascular biology. 2018 May 03.
• 1. Schmidt RA
  2. Morrell CN
  3. Ling FS
  4. Simlote P
  5. Fernandez G
  6. Rich DQ
  7. Adler D
  8. Gervase J
  9. Cameron SJ
  The platelet phenotype in patients with ST-segment elevation myocardial infarction is different from non-ST-segment elevation myocardial infarction.; Translational research : the journal of laboratory and clinical medicine; Vol 195. 2018 May.
• 1. Yang M
  2. Kholmukhamedov A
  3. Schulte ML
  4. Cooley BC
  5. Scoggins NO
  6. Wood JP
  7. Cameron SJ
  8. Morrell CN
  9. Jobe SM
  10. Silverstein RL
  Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo.; Blood advances; Vol 2(21). 2018 Jan 13.
• 1. Chapman LM
  2. Ture SK
  3. Field DJ
  4. Morrell CN
  miR-451 limits CD4+ T cell proliferative responses to infection in mice.; Immunologic research; Vol 65(4). 2017 Aug.
• 1. Yang M
  2. Cooley BC
  3. Li W
  4. Chen Y
  5. Vasquez-Vivar J
  6. Scoggins NO
  7. Cameron SJ
  8. Morrell CN
  9. Silverstein RL
  Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions.; Blood; Vol 129(21). 2017 May 25.
• 1. Croft DP
  2. Cameron SJ
  3. Morrell CN
  4. Lowenstein CJ
  5. Ling F
  6. Zareba W
  7. Hopke PK
  8. Utell MJ
  9. Thurston SW
  10. Thevenet-Morrison K
  11. Evans KA
  12. Chalupa D
  13. Rich DQ
  Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients.; Environmental research; Vol 154. 2017 Apr.
• 1. Morrell CN
  Platelets: killers of parasites or patients?; Blood; Vol 129(12). 2017 Mar 23.
• 1. Zhu QM
  2. Ko KA
  3. Ture S
  4. Mastrangelo MA
  5. Chen MH
  6. Johnson AD
  7. O'Donnell CJ
  8. Morrell CN
  9. Miano JM
  10. Lowenstein CJ
  Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.; Arteriosclerosis, thrombosis, and vascular biology; Vol 37(2). 2017 Feb.
• 1. Field DJ
  2. Aggrey-Amable AA
  3. Blick SK
  4. Ture SK
  5. Johanson A
  6. Cameron SJ
  7. Roy S
  8. Morrell CN
  Platelet factor 4 increases bone marrow B cell development and differentiation.; Immunologic research; Vol 65(5). 2017 Jan.
• 1. Batchu SN
  2. Hughson A
  3. Wadosky KM
  4. Morrell CN
  5. Fowell DJ
  6. Korshunov VA
  Role of Axl in T-Lymphocyte Survival in Salt-Dependent Hypertension.; Arteriosclerosis, thrombosis, and vascular biology. 2016 Jun 30.
• 1. Xu S
  2. Liu B
  3. Yin M
  4. Koroleva M
  5. Mastrangelo M
  6. Ture S
  7. Morrell CN
  8. Zhang DX
  9. Fisher EA
  10. Jin ZG
  A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.; Oncotarget; Vol 7(25). 2016 Jun 21.
• 1. Modjeski KL
  2. Levy SC
  3. Ture SK
  4. Field DJ
  5. Shi G
  6. Ko K
  7. Zhu Q
  8. Morrell CN
  Glutamate Receptor Interacting Protein 1 Regulates CD4(+) CTLA-4 Expression and Transplant Rejection.; American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons; Vol 16(5). 2016 May.
• 1. Lannan KL
  2. Refaai MA
  3. Ture SK
  4. Morrell CN
  5. Blumberg N
  6. Phipps RP
  7. Spinelli SL
  Resveratrol preserves the function of human platelets stored for transfusion.; British journal of haematology; Vol 172(5). 2016 Mar.
• 1. Jackson JW
  2. Singh MV
  3. Singh VB
  4. Jones LD
  5. Davidson GA
  6. Ture S
  7. Morrell CN
  8. Schifitto G
  9. Maggirwar SB
  Novel Antiplatelet Activity of Minocycline Involves Inhibition of MLK3-p38 Mitogen Activated Protein Kinase Axis.; PloS one; Vol 11(6). 2016.
• 1. Modjeski KL
  2. Ture SK
  3. Field DJ
  4. Cameron SJ
  5. Morrell CN
  Glutamate Receptor Interacting Protein 1 Mediates Platelet Adhesion and Thrombus Formation.; PloS one; Vol 11(9). 2016.
• 1. Batchu SN
  2. Xia J
  3. Ko KA
  4. Doyley MM
  5. Abe J
  6. Morrell CN
  7. Korshunov VA
  Axl modulates immune activation of smooth muscle cells in vein graft remodeling.; American journal of physiology. Heart and circulatory physiology; Vol 309(6). 2015 Sep 15.
• 1. Spitalnik SL
  2. Triulzi D
  3. Devine DV
  4. Dzik WH
  5. Eder AF
  6. Gernsheimer T
  7. Josephson CD
  8. Kor DJ
  9. Luban NL
  10. Roubinian NH
  11. Mondoro T
  12. Welniak LA
  13. Zou S
  14. Glynn S
  2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.; Transfusion; Vol 55(9). 2015 Sep.
• 1. Cameron SJ
  2. Ture SK
  3. Mickelsen D
  4. Chakrabarti E
  5. Modjeski KL
  6. McNitt S
  7. Seaberry M
  8. Field DJ
  9. Le NT
  10. Abe J
  11. Morrell CN
  Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion.; Circulation; Vol 132(1). 2015 Jul 7.
• 1. Cameron SJ
  2. Morrell CN
  3. Bao C
  4. Swaim AF
  5. Rodriguez A
  6. Lowenstein CJ
  A Novel Anti-Inflammatory Effect for High Density Lipoprotein.; PloS one; Vol 10(12). 2015.
• 1. Morrell CN
  Understanding platelets in malaria infection.; Current opinion in hematology; Vol 21(5). 2014 Sep.
• 1. Wang L
  2. Soe NN
  3. Sowden M
  4. Xu Y
  5. Modjeski K
  6. Baskaran P
  7. Kim Y
  8. Smolock EM
  9. Morrell CN
  10. Berk BC
  Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling.; Thrombosis and haemostasis; Vol 111(5). 2014 May 05.
• 1. Morrell CN
  2. Aggrey AA
  3. Chapman LM
  4. Modjeski KL
  Emerging roles for platelets as immune and inflammatory cells.; Blood; Vol 123(18). 2014 May 1.
• 1. Metcalf Pate KA
  2. Lyons CE
  3. Dorsey JL
  4. Queen SE
  5. Adams RJ
  6. Morrell CN
  7. Mankowski JL
  TGFβ-Mediated Downregulation of Thrombopoietin Is Associated With Platelet Decline in Asymptomatic SIV Infection.; Journal of acquired immune deficiency syndromes (1999); Vol 65(5). 2014 Apr 15.
• 1. Modjeski KL
  2. Morrell CN
  Small cells, big effects: the role of platelets in transplant vasculopathy.; Journal of thrombosis and thrombolysis; Vol 37(1). 2014 Jan.
• 1. Shi G
  2. Field DJ
  3. Long X
  4. Mickelsen D
  5. Ko KA
  6. Ture S
  7. Korshunov VA
  8. Miano JM
  9. Morrell CN
  Platelet factor 4 mediates vascular smooth muscle cell injury responses.; Blood; Vol 121(21). 2013 May 23.
• 1. Aggrey AA
  2. Srivastava K
  3. Ture S
  4. Field DJ
  5. Morrell CN
  Platelet induction of the acute-phase response is protective in murine experimental cerebral malaria.; Journal of immunology (Baltimore, Md. : 1950); Vol 190(9). 2013 May 1.
• 1. Chapman LM
  2. Aggrey AA
  3. Field DJ
  4. Srivastava K
  5. Ture S
  6. Yui K
  7. Topham DJ
  8. Baldwin WM
  9. Morrell CN
  Platelets present antigen in the context of MHC class I.; Journal of immunology (Baltimore, Md. : 1950); Vol 189(2). 2012 Jul 15.
• 1. Morrell CN
  2. Maggirwar SB
  Recently recognized platelet agonists.; Current opinion in hematology; Vol 18(5). 2011 Sep.
• 1. Shi G
  2. Morrell CN
  Platelets as initiators and mediators of inflammation at the vessel wall.; Thrombosis research; Vol 127(5). 2011 May.
• 1. Morrell CN
  2. Srivastava K
  3. Swaim A
  4. Lee MT
  5. Chen J
  6. Nagineni C
  7. Hooks JJ
  8. Detrick B
  Beta interferon suppresses the development of experimental cerebral malaria.; Infection and immunity; Vol 79(4). 2011 Apr.
• 1. Davidson DC
  2. Hirschman MP
  3. Spinelli SL
  4. Morrell CN
  5. Schifitto G
  6. Phipps RP
  7. Maggirwar SB
  Antiplatelet activity of valproic acid contributes to decreased soluble CD40 ligand production in HIV type 1-infected individuals.; Journal of immunology (Baltimore, Md. : 1950); Vol 186(1). 2011 Jan 1.
• 1. Morrell CN
  Immunomodulatory mediators in platelet transfusion reactions.; Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program; Vol 2011. 2011.
• 1. Ombrello C
  2. Block RC
  3. Morrell CN
  Our expanding view of platelet functions and its clinical implications.; Journal of cardiovascular translational research; Vol 3(5). 2010 Oct.
• 1. Srivastava K
  2. Field DJ
  3. Aggrey A
  4. Yamakuchi M
  5. Morrell CN
  Platelet factor 4 regulation of monocyte KLF4 in experimental cerebral malaria.; PloS one; Vol 5(5). 2010.
• 1. Steele BM
  2. Harper MT
  3. Macaulay IC
  4. Morrell CN
  5. Perez-Tamayo A
  6. Foy M
  7. Habas R
  8. Poole AW
  9. Fitzgerald DJ
  10. Maguire PB
  Canonical Wnt signaling negatively regulates platelet function.; Proceedings of the National Academy of Sciences of the United States of America; Vol 106(47). 2009 Nov 24.
• 1. Sun H
  2. Swaim A
  3. Herrera JE
  4. Becker D
  5. Becker L
  6. Srivastava K
  7. Thompson LE
  8. Shero MR
  9. Perez-Tamayo A
  10. Suktitipat B
  11. Mathias R
  12. Contractor A
  13. Faraday N
  14. Morrell CN
  Platelet kainate receptor signaling promotes thrombosis by stimulating cyclooxygenase activation.; Circulation research; Vol 105(6). 2009 Sep 11.
• 1. Jeong Y
  2. Chaupin DF
  3. Matsushita K
  4. Yamakuchi M
  5. Cameron SJ
  6. Morrell CN
  7. Lowenstein CJ
  Aldosterone activates endothelial exocytosis.; Proceedings of the National Academy of Sciences of the United States of America; Vol 106(10). 2009 Mar 10.
• 1. Srivastava K
  2. Cockburn IA
  3. Swaim A
  4. Thompson LE
  5. Tripathi A
  6. Fletcher CA
  7. Shirk EM
  8. Sun H
  9. Kowalska MA
  10. Fox-Talbot K
  11. Sullivan D
  12. Zavala F
  13. Morrell CN
  Platelet factor 4 mediates inflammation in experimental cerebral malaria.; Cell host & microbe; Vol 4(2). 2008 Aug 14.
• 1. Morrell CN
  2. Sun H
  3. Ikeda M
  4. Beique JC
  5. Swaim AM
  6. Mason E
  7. Martin TV
  8. Thompson LE
  9. Gozen O
  10. Ampagoomian D
  11. Sprengel R
  12. Rothstein J
  13. Faraday N
  14. Huganir R
  15. Lowenstein CJ
  Glutamate mediates platelet activation through the AMPA receptor.; The Journal of experimental medicine; Vol 205(3). 2008 Mar 17.
• 1. Shi C
  2. Parker AR
  3. Hua L
  4. Morrell CN
  5. Lee SC
  6. Bandaru V
  7. Dumler JS
  8. Wu TC
  9. Eshleman JR
  Anti-gene padlocks eliminate Escherichia coli based on their genotype.; The Journal of antimicrobial chemotherapy; Vol 61(2). 2008 Feb.
• 1. Yamakuchi M
  2. Ferlito M
  3. Morrell CN
  4. Matsushita K
  5. Fletcher CA
  6. Cao W
  7. Lowenstein CJ
  Exocytosis of endothelial cells is regulated by N-ethylmaleimide-sensitive factor.; Methods in molecular biology (Clifton, N.J.); Vol 440. 2008.
• 1. Morrell CN
  2. Mason EA
  3. Martin TV
  4. Swaim AM
  5. Ballard M
  6. Murata K
  7. Baldwin WM
  Alloantibodies to MHC Induce Platelet-Endothelial Cell Interactions; Circulation Research; Vol 102(7), pp. 777-785. 2008 Jan 01.
• 1. Matsushita K
  2. Morrell CN
  3. Mason RJ
  4. Yamakuchi M
  5. Khanday FA
  6. Irani K
  7. Lowenstein CJ
  Hydrogen peroxide regulation of endothelial exocytosis by inhibition of N-ethylmaleimide sensitive factor.; The Journal of cell biology; Vol 170(1). 2005 Jul 4.
• 1. Morrell CN
  2. Matsushita K
  3. Lowenstein CJ
  A novel inhibitor of N-ethylmaleimide-sensitive factor decreases leukocyte trafficking and peritonitis.; The Journal of pharmacology and experimental therapeutics; Vol 314(1). 2005 Jul.
• 1. Yamakuchi M
  2. Greer JJ
  3. Cameron SJ
  4. Matsushita K
  5. Morrell CN
  6. Talbot-Fox K
  7. Baldwin WM
  8. Lefer DJ
  9. Lowenstein CJ
  HMG-CoA reductase inhibitors inhibit endothelial exocytosis and decrease myocardial infarct size.; Circulation research; Vol 96(11). 2005 Jun 10.
• 1. Matsushita K
  2. Morrell CN
  3. Lowenstein CJ
  A novel class of fusion polypeptides inhibits exocytosis.; Molecular pharmacology; Vol 67(4). 2005 Apr.
• 1. Morrell CN
  2. Matsushita K
  3. Chiles K
  4. Scharpf RB
  5. Yamakuchi M
  6. Mason RJ
  7. Bergmeier W
  8. Mankowski JL
  9. Baldwin WM
  10. Faraday N
  11. Lowenstein CJ
  Regulation of platelet granule exocytosis by S-nitrosylation.; Proceedings of the National Academy of Sciences of the United States of America; Vol 102(10). 2005 Mar 8.
• 1. Matsushita K
  2. Yamakuchi M
  3. Morrell CN
  4. Ozaki M
  5. O'Rourke B
  6. Irani K
  7. Lowenstein CJ
  Vascular endothelial growth factor regulation of Weibel-Palade-body exocytosis.; Blood; Vol 105(1). 2005 Jan 1.
• 1. Bhatia R
  2. Matsushita K
  3. Yamakuchi M
  4. Morrell CN
  5. Cao W
  6. Lowenstein CJ
  Ceramide triggers Weibel-Palade body exocytosis.; Circulation research; Vol 95(3). 2004 Aug 6.
• 1. Matsushita K
  2. Morrell CN
  3. Lowenstein CJ
  Sphingosine 1-phosphate activates Weibel-Palade body exocytosis.; Proceedings of the National Academy of Sciences of the United States of America; Vol 101(31). 2004 Aug 3.
• 1. Matsushita K
  2. Morrell CN
  3. Cambien B
  4. Yang SX
  5. Yamakuchi M
  6. Bao C
  7. Hara MR
  8. Quick RA
  9. Cao W
  10. O'Rourke B
  11. Lowenstein JM
  12. Pevsner J
  13. Wagner DD
  14. Lowenstein CJ
  Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor.; Cell; Vol 115(2). 2003 Oct 17.
• 1. Chen WY
  2. Zeng X
  3. Carter MG
  4. Morrell CN
  5. Chiu Yen RW
  6. Esteller M
  7. Watkins DN
  8. Herman JG
  9. Mankowski JL
  10. Baylin SB
  Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.; Nature genetics; Vol 33(2). 2003 Feb.
• 1. Morrell CN
  2. Volk MV
  3. Mankowski JL
  A carcinoid tumor in the gallbladder of a dog.; Veterinary pathology; Vol 39(6). 2002 Nov.
• 1. Mathiowitz E
  2. Jacob JS
  3. Jong YS
  4. Carino GP
  5. Chickering DE
  6. Chaturvedi P
  7. Santos CA
  8. Vijayaraghavan K
  9. Montgomery S
  10. Bassett M
  11. Morrell C
  Biologically erodable microspheres as potential oral drug delivery systems.; Nature; Vol 386(6623). 1997 Mar 27.
• 1. Chickering DE
  2. Jacob JS
  3. Desai M
  4. Harrison WP
  5. Morrell CN
  6. Chatuverdi P
  7. Mathiowitz E
  Bioadhesive Microspheres: III. An In Vivo Transit and Bioavailability Study of Drug-Loaded Alginate and Poly(Fumaric-co-Sebacic Anhydride) Microspheres; Journal of Controlled Release; Vol 48, pp. 35-46. 1997 Jan 01.