URMC / Cardiovascular Research Institute / Research / Yao Lab / Publications

Recent Publications

1. Tumenbayar BI
2. Tutino VM
3. Brazzo JA
4. Yao P
5. Bae Y
FAK and p130Cas modulate stiffness-mediated early transcription and cellular metabolism.; bioRxiv : the preprint server for biology. 2024 Jan 16.
1. Wu J
2. Hollinger J
3. Bonanno E
4. Jiang F
5. Yao P
Cardiomyocyte-Specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; Cells; Vol 13(1). 2023 Dec 22.
1. Wu J
2. Hollinger J
3. Bonanno E
4. Jiang F
5. Yao P
Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy.; bioRxiv : the preprint server for biology. 2023 Sep 22.
1. Wu J
2. Subbaiah KCV
3. Hedaya O
4. Chen S
5. Munger J
6. Tang WHW
7. Yan C
8. Yao P
FAM210A regulates mitochondrial translation and maintains cardiac mitochondrial homeostasis.; Cardiovascular research. 2023 Jul 31.
1. Hollinger J
2. Wu J
3. Awayda KM
4. O'Connell MR
5. Yao P
Expression and purification of the mitochondrial transmembrane protein FAM210A in Escherichia coli.; Protein expression and purification; Vol 210, pp. 106322. 2023 Jun 15.
1. Hedaya OM
2. Subbaiah KCV
3. Jiang F
4. Xie LH
5. Wu J
6. Khor E
7. Zhu M
8. Mathews DH
9. Proschel C
10. Yao P
Secondary structures that regulate mRNA translation provide insights for ASO-mediated modulation of cardiac hypertrophy.; bioRxiv : the preprint server for biology. 2023 Jun 15.
1. Wu J
2. Subbaiah KCV
3. Hedaya O
4. Chen S
5. Munger J
6. Tang WHW
7. Yan C
8. Yao P
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.; bioRxiv : the preprint server for biology. 2023 May 22.
1. Jiang F
2. Hedaya OM
3. Khor E
4. Wu J
5. Auguste M
6. Yao P
RNA binding protein PRRC2B mediates translation of specific mRNAs and regulates cell cycle progression.; Nucleic acids research. 2023 May 01.
1. Subbaiah KCV
2. Wu J
3. Tang WHW
4. Yao P
Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis.; Journal of cardiovascular development and disease; Vol 10(2). 2023 Jan 29.
1. Subbaiah KCV
2. Wu J
3. Tang WHW
4. Yao P
FAM114A1 influences cardiac pathological remodeling by regulating angiotensin II signaling.; JCI insight. 2022 Jun 07.
1. Wu J
2. Venkata Subbaiah KC
3. Jiang F
4. Hedaya O
5. Mohan A
6. Yang T
7. Welle K
8. Ghaemmaghami S
9. Tang WHW
10. Small E
11. Yan C
12. Yao P
MicroRNA-574 regulates FAM210A expression and influences pathological cardiac remodeling.; EMBO molecular medicine. 2020 Dec 28.
1. Lyu QR
2. Yao P
3. Miano JM
Generating a CRISPR knockout mouse through a strong premature termination codon: a cautionary tale.; Journal of biomedical research; Vol 35(2). 2020 Dec 25.
1. Wu J
2. Subbaiah KCV
3. Xie LH
4. Jiang F
5. Khor ES
6. Mickelsen DM
7. Myers JR
8. Tang WW
9. Yao P
Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-fibrotic Protein Synthesis During Cardiac Fibrosis.; Circulation research. 2020 Jul 01.
1. Zhao S
2. Dejanovic D
3. Yao P
4. Bhilocha S
5. Sadler T
6. Schirbel A
7. West G
8. Doyon G
9. Lopez R
10. Mao R
11. Kurada S
12. El Ouali S
13. Grassl G
14. Fox PL
15. Cruise M
16. Worthley DL
17. de la Motte C
18. Fiocchi C
19. Rieder F
Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation.; Mucosal immunology; Vol 13(4). 2020 Jul.
1. Yao P
2. Fox PL
Aminoacyl-tRNA synthetases in cell signaling.; The Enzymes; Vol 48. 2020.
1. Ji C
2. Li Y
3. Kittredge A
4. Hopiavuori A
5. Ward N
6. Yao P
7. Fukuda Y
8. Zhang Y
9. Tsang SH
10. Yang T
Investigation and Restoration of BEST1 Activity in Patient-derived RPEs with Dominant Mutations.; Scientific reports; Vol 9(1). 2019 Dec 13.
1. Chen S
2. Zhang Y
3. Lighthouse JK
4. Mickelsen DM
5. Wu J
6. Yao P
7. Small EM
8. Yan C
A Novel Role of Cyclic Nucleotide Phosphodiesterase 10A in Pathological Cardiac Remodeling and Dysfunction.; Circulation. 2019 Dec 05.
1. Venkata Subbaiah KC
2. Wu J
3. Potdar A
4. Yao P
hnRNP L-mediated RNA switches function as a hypoxia-induced translational regulon.; Biochemical and biophysical research communications; Vol 516(3). 2019 Aug 27.
1. Venkata Subbaiah KC
2. Hedaya O
3. Wu J
4. Jiang F
5. Yao P
Mammalian RNA switches: Molecular rheostats in gene regulation, disease, and medicine.; Computational and structural biotechnology journal; Vol 17. 2019.
1. Halawani D
2. Gogonea V
3. DiDonato JA
4. Pipich V
5. Yao P
6. China A
7. Topbas C
8. Vasu K
9. Arif A
10. Hazen SL
11. Fox PL
Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains.; The Journal of biological chemistry; Vol 293(23). 2018 Jun 08.
1. Arif A
2. Yao P
3. Terenzi F
4. Jia J
5. Ray PS
6. Fox PL
The GAIT translational control system.; Wiley interdisciplinary reviews. RNA; Vol 9(2). 2018 Mar.
1. Techasintana P
2. Ellis JS
3. Glascock J
4. Gubin MM
5. Ridenhour SE
6. Magee JD
7. Hart ML
8. Yao P
9. Zhou H
10. Whitney MS
11. Franklin CL
12. Martindale JL
13. Gorospe M
14. Davis WJ
15. Fox PL
16. Li X
17. Atasoy U
The RNA-Binding Protein HuR Posttranscriptionally Regulates IL-2 Homeostasis and CD4+ Th2 Differentiation.; ImmunoHorizons; Vol 1(6). 2017 Aug 01.
1. Yao P
2. Wu J
3. Lindner D
4. Fox PL
Interplay between miR-574-3p and hnRNP L regulates VEGFA mRNA translation and tumorigenesis.; Nucleic acids research. 2017 May 17.
1. Yao P
2. Eswarappa SM
3. Fox PL
"Translational control mechanisms in angiogenesis and vascular biology."; Current Atherosclerosis Reports. 2015 Jan 01.
1. Huang Q
2. Zhou X
3. Hu Q
4. Lei H
5. Fang Z
6. Yao P
7. Wang AE
"A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity."; RNA; Vol 20, pp. 1440-1450. 2014 Jan 01.
1. Jia J
2. Yao P
3. Arif A
4. Fox PL
Regulation and dysregulation of 3'UTR-mediated translational control.; Current opinion in genetics & development; Vol 23(1). 2013 Feb.
1. Yao P
2. Potdar AA
3. Ray PS
4. Eswarappa SM
5. Flagg AC
6. Willard B
7. Fox PL
The HILDA complex coordinates a conditional switch in the 3'-untranslated region of the VEGFA mRNA.; PLoS biology; Vol 11(8). 2013.
1. Zhou H
2. Yu M
3. Fukuda K
4. Im J
5. Yao P
6. Cui W
7. Bulek K
8. Zepp J
9. Wan Y
10. Kim TW
11. Yin W
12. Ma V
13. Thomas J
14. Gu J
15. Wang J
16. DiCorleto PE
17. Fox PL
18. Qin J
19. Li AX
"IRAK-M mediates Toll-like receptor/IL-1R-induced NFkB activation and cytokine production."; EMBO Journal; Vol 32, pp. 583-596. 2013 Jan 01.
1. Herjan T
2. Yao P
3. Qian W
4. Li X
5. Liu C
6. Bulek K
7. Sun D
8. Yang W
9. Zhu J
10. He A
11. Carman JA
12. Erzurum SC
13. Lipshitz HD
14. Fox PL
15. Hamilton TA
16. Li AX
"HuR is required for IL-17-induced Act1-mediated CXCL1 and CXCL5 mRNA stabilization."; Journal of Immunology; Vol 191, pp. 640-649. 2013 Jan 01.
1. Yao P
2. Fox PL
"Aminoacyl-tRNA synthetases in medicine and disease."; EMBO Molecular Medicine; Vol 5, pp. 332-343. 2013 Jan 01.
1. Yao P
2. Poruri K
3. Martinis SA
4. Fox PL
"Non-catalytic regulation of gene expression by aminoacyl-tRNA synthetases."; Topics in Current Chemistry; Vol 344, pp. 167-187. 2013 Jan 01.
1. Yao P
2. Potdar AA
3. Arif A
4. Ray PS
5. Mukhopadhyay R
6. Willard B
7. Xu Y
8. Yan J
9. Saidel GM
10. Fox PL
Coding region polyadenylation generates a truncated tRNA synthetase that counters translation repression.; Cell; Vol 149(1). 2012 Mar 30.
1. Yao P
2. Fox PL
"A truncated tRNA synthetase directs a 'translational trickle' of gene expression."; Cell Cycle; Vol 11. 2012 Jan 01.
1. Huang Q
2. Yao P
3. Eriani G
4. Wang E
"In vivo identification of essential nucleotides in tRNALeu to its functions by using a constructed yeast tRNALeu knockout strain."; Nucleic Acids Research; Vol 40, pp. 10463-10477. 2012 Jan 01.
1. Jafarifar F
2. Yao P
3. Eswarappa SM
4. Fox PL
"Repression of VEGFA by CA-rich element-binding microRNAs is modulated by hnRNP L."; EMBO Journal; Vol 30:, pp. 1324-1334. 2011 Jan 01.
1. Chen X
2. Ma J
3. Tan M
4. Yao P
5. Hu Q
6. Eriani G
7. Wang E
"Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase."; Nucleic Acids Research; Vol 39:, pp. 235-247. 2011 Jan 01.
1. Yao P
2. Fox PL
"Sex lethal and upstream ORFs: a bait-and-trap system for ribosomes."; Genome Biology; Vol 12:(12). 2011 Jan 01.
1. Yin W
2. Wan Y
3. Kim TW
4. Yao P
5. Xiao H
6. Zhou H
7. Xiao J
8. Fox P
9. Li X
"The kinase activity of interleukin-1 receptor-associated kinase 2 is essential for lipopolysaccharide-mediated cytokine and chemokine mRNA stability and translation."; J Interferon Cytokine Research; Vol 31:, pp. 415-422. 2011 Jan 01.
1. Zhu B
2. Yao P
3. Tan M
4. Eriani G
5. Wang ED
tRNA-independent pretransfer editing by class I leucyl-tRNA synthetase.; The Journal of biological chemistry; Vol 284(6). 2009 Feb 06.
1. Zhou X
2. Yao P
3. Zhu B
4. Ruan L
5. Wang E
"A unique insertion in the CP1 domain of Giardia lamblia leucyl-tRNA synthetase."; Biochemistry; Vol 48:, pp. 1340-1347. 2009 Jan 01.
1. He R
2. Zu L
3. Yao P
4. Chen X
5. Wang E
"Two non-redundant fragments in the N-terminal peptide of human cytosolic methionyl-tRNA synthetase were indispensable for the multi-synthetase complex incorporation and enzyme activity."; Biochimica et Biophysica Acta; Vol 1794:, pp. 347-354. 2009 Jan 01.
1. Ray PS
2. Jia J
3. Yao P
4. Majumder M
5. Hatzoglou M
6. Fox PL
"A stress-responsive RNA switch regulates VEGFA expression."; Nature; Vol 457:, pp. 915-919. 2008 Jan 01.
1. Yao P
2. Zhou X
3. He R
4. Xue M
5. Zheng Y
6. Wang Y
7. Wang E
"Unique residues crucial for optimal editing in the yeast cytoplasmic leucyl-tRNA synthetase revealed by a novel knockout yeast strain."; Journal of Biological Chemistry; Vol 283:, pp. 22591-22600. 2008 Jan 01.
1. Yao P
2. Zhu B
3. Jaeger S
4. Eriani G
5. Wang E
"Recognition of tRNALeu by Aquifex aeolicus leucyl-tRNA synthetase during aminoacylation and editing steps."; Nucleic Acids Research; Vol 36:, pp. 2728-2738. 2008 Jan 01.