URMC / Center for Translational Neuromedicine / Publications Publications Cankar NBeschorner NTsopanidou AQvist FLColaço ARAndersen MKjaerby CDelle CLambert MMundt FWeikop PJucker MMann MSkotte NHNedergaard M Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model.; Cell reports; Vol 43(11), pp. 114977. 2024 Nov 13. Sun QPeng SXu QWeikop PHussain RSong WNedergaard MDing F Enhancing glymphatic fluid transport by pan-adrenergic inhibition suppresses epileptogenesis in male mice.; Nature communications; Vol 15(1), pp. 9600. 2024 Nov 06. Wostyn PMader THGibson CRNedergaard M New insights in brain-to-eye transport: can excess cerebrospinal fluid in astronauts escape into the eye?; Eye (London, England). 2024 Nov 04. Li BSun QDing FXu QKang NXue YLadron-de-Guevara AHirase HWeikop PGong SNathan SNedergaard M Anti-seizure effects of norepinephrine-induced free fatty acid release.; Cell metabolism. 2024 Oct 29. Knudsen-Clark AMMwangi DCazarin JMorris KBaker CHablitz LMMcCall MNKim MAltman BJ Circadian rhythms of macrophages are altered by the acidic tumor microenvironment.; EMBO reports. 2024 Oct 16. Iden CRMustafa SMØgaard NHenriksen TJensen SØAhlborn LBEgebjerg KBaeksgaard LGarbyal RSNedergaard MKAchiam MPAndersen CLMau-Sørensen M Circulating tumor DNA predicts recurrence and survival in patients with resectable gastric and gastroesophageal junction cancer.; Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2024 Oct 05. Asiminas AGomolka RSGregoriades SHirase HNedergaard MBeinlich FRM Protocol to study oxygen dynamics in the in vivo mouse brain using bioluminescence microscopy.; STAR protocols; Vol 5(4), pp. 103334. 2024 Sep 25. Cao QYang SWang XSun HChen WWang YGao JWu YYang QChen XYuan SXiao MNedergaard MHuo YLiu Q Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer's disease.; The Journal of experimental medicine; Vol 221(11). 2024 Sep 24. Kroesbergen ERiesselmann LVGomolka RSPlá VEsmail TStenmo VHKovács ERNielsen ESGoldman SANedergaard MWeikop PMori Y Glymphatic clearance is enhanced during sleep.; bioRxiv : the preprint server for biology. 2024 Sep 15. Plá VBitsika SGiannetto MJLadrón-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Response to Commentary on "Structural characterization of SLYM - a 4th meningeal membrane" by Julie Siegenthaler and Christer Betsholtz.; Fluids and barriers of the CNS; Vol 21(1), pp. 70. 2024 Sep 09. Xu CNedergaard MFowell DJFriedl PJi N Multiphoton fluorescence microscopy for in vivo imaging.; Cell; Vol 187(17), pp. 4458-4487. 2024 Aug 22. Du TRaghunandan AMestre HPlá VLiu GLadrón-de-Guevara ANewbold ETobin PGahn-Martinez DPattanayak SHuang QPeng WNedergaard MKelley DH Restoration of cervical lymphatic vessel function in aging rescues cerebrospinal fluid drainage.; Nature aging. 2024 Aug 15. Smyth LCDBeschorner NNedergaard MKipnis J Cellular Contributions to Glymphatic and Lymphatic Waste Clearance in the Brain.; Cold Spring Harbor perspectives in biology. 2024 Aug 12. Wostyn PNedergaard M The potential influence of sleep on translaminar pressure dynamics and ocular glymphatic outflow in microgravity: implications for optic disc edema in astronauts.; Eye (London, England). 2024 Jul 30. Kaag Rasmussen MMøllgård KBork PARWeikop PEsmail TDrici LWewer Albrechtsen NJCarlsen JFHuynh NPTGhitani NMann MGoldman SAMori YChesler ATNedergaard M Trigeminal ganglion neurons are directly activated by influx of CSF solutes in a migraine model.; Science (New York, N.Y.); Vol 385(6704), pp. 80-86. 2024 Jul 04. Plá VBitsika SGiannetto MJLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K In response to "An "outer subarachnoid space": fact or artifact? A commentary on "Structural characterization of SLYM: a 4th meningeal membrane" fluids and barriers of the CNS (2023) 20:93 by V. Plá et al.".; Fluids and barriers of the CNS; Vol 21(1), pp. 49. 2024 Jun 03. Ge GRSong WGiannetto MJRolland JPNedergaard MParker KJ Mouse Brain Elastography Changes with Sleep/Wake Cycles, Aging, and Alzheimer's Disease.; NeuroImage. 2024 May 30. Persson NDÅLohela TJMortensen KNRosenholm MLi QWeikop PNedergaard MLilius TO Anesthesia blunts carbon dioxide effects on glymphatic cerebrospinal fluid dynamics in mechanically ventilated rats.; Anesthesiology. 2024 May 24. Delle CWang XNedergaard M The Ocular Glymphatic System-Current Understanding and Future Perspectives.; International journal of molecular sciences; Vol 25(11). 2024 May 24. Zhou XAMan WLiu XChoi SJiang YHike DCid LGLin CNedergaard MYu X Mapping glymphatic solute transportation through the perivascular space of hippocampal arterioles with 14 Tesla MRI.; bioRxiv : the preprint server for biology. 2024 May 20. Mader THGibson CRWostyn PNedergaard M Enlargement of Perivascular Spaces as a Downstream Consequence of Spaceflight Analog-Induced Alterations in Cerebral Venous Hemodynamics.; AJNR. American journal of neuroradiology; Vol 45(5), pp. E6. 2024 May 09. Mariani JNMansky BMadsen PMSalinas DKesmen DHuynh NPTKuypers NJKesel ERBates JPayne CChandler-Militello DBenraiss AGoldman SA Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells.; Nature communications; Vol 15(1), pp. 3873. 2024 May 08. Wostyn PNedergaard M A new look at ocular glymphatic transport in space.; Journal of applied physiology (Bethesda, Md. : 1985); Vol 136(5), pp. 1129-1130. 2024 May 01. Deng SHu YChen SXue YYao DSun QNedergaard MWang WDing F Chronic sleep fragmentation impairs brain interstitial clearance in young wildtype mice.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2024 Apr 19. van Osch MJPWåhlin AScheyhing PMossige IHirschler LEklund AMogensen KGomolka RRadbruch AQvarlander SDecker ANedergaard MMori YEide PKDeike KRingstad G Human brain clearance imaging: Pathways taken by magnetic resonance imaging contrast agents after administration in cerebrospinal fluid and blood.; NMR in biomedicine. 2024 Apr 18. Bork PARHauglund NLMori YMøllgård KHjorth PGNedergaard M Modeling of brain efflux: Constraints of brain surfaces.; Proceedings of the National Academy of Sciences of the United States of America; Vol 121(16), pp. e2318444121. 2024 Apr 10. Beinlich FRMAsiminas AUntiet VBojarowska ZPlá VSigurdsson BTimmel VGehrig LGraber MHHirase HNedergaard M Oxygen imaging of hypoxic pockets in the mouse cerebral cortex.; Science (New York, N.Y.); Vol 383(6690), pp. 1471-1478. 2024 Mar 28. Delle CWang XGiannetto MNewbold EPeng WGomolka RSLadrón-de-Guevara ACankar NSchiøler Nielsen EKjaerby CWeikop PMori YNedergaard M Transient but not chronic hyperglycemia accelerates ocular glymphatic transport.; Fluids and barriers of the CNS; Vol 21(1), pp. 26. 2024 Mar 12. Ding FSun QLong CRasmussen RNPeng SXu QKang NSong WWeikop PGoldman SANedergaard M Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration.; Brain : a journal of neurology. 2024 Mar 11. Hablitz LNedergaard M Synchronized neuronal activity drives waste fluid flow.; Nature. 2024 Feb 28. Giannetto MJGomolka RSGahn-Martinez DNewbold EJBork PARChang EGresser MThompson TMori YNedergaard M Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271.; Glia. 2024 Feb 16. Beschorner NNedergaard M Glymphatic system dysfunction in neurodegenerative diseases.; Current opinion in neurology. 2024 Feb 13. Franklin RJMBodini BGoldman SA Remyelination in the Central Nervous System.; Cold Spring Harbor perspectives in biology. 2024 Feb 05. Patel KSTessema KKKawaguchi RDudley LAlvarado AGMuthukrishnan SDPerryman THagiwara ASwarup VLiau LMWang ACYong WGeschwind DHNakano IGoldman SAEverson RGEllingson BMKornblum HI Single-nucleus expression characterization of non-enhancing region of recurrent high-grade glioma.; Neuro-oncology advances; Vol 6(1), pp. vdae005. 2024 Jan 25. Eisen ANedergaard MGray EKiernan MC THE GLYMPHATIC SYSTEM AND AMYOTROPHIC LATERAL SCLEROSIS.; Progress in neurobiology. 2024 Jan 22. Zhao LQiu ZYang ZXu LPearce TMWu QYang KLi FSaulnier OFei FYu HGimple RCVaradharajan VLiu JHendrikse LDFong VWang WZhang JLv DLee DLehrich BMJin COuyang LDixit DWu HWang XSloan AEWang XHuan TMark Brown JGoldman SATaylor MDZhou SRich JN Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.; Nature cancer. 2024 Jan 03. Hussain RNedergaard M Managing noradrenaline after traumatic brain injury.; Clinical and translational medicine; Vol 14(1), pp. e1562. 2024 Jan. Goldman SAFranklin RJMOsorio J Stem and progenitor cell-based therapy of myelin disorders.; Handbook of clinical neurology; Vol 205, pp. 283-295. 2024. Untiet VNedergaard MVerkhratsky A Astrocyte chloride, excitatory-inhibitory balance and epilepsy.; Neural regeneration research; Vol 19(9), pp. 1887. 2023 Dec 15. Dietz AGWeikop PHauglund NAndersen MPetersen NCRose LHirase HNedergaard M Local extracellular K+ in cortex regulates norepinephrine levels, network state, and behavioral output.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(40), pp. e2305071120. 2023 Sep 29. Hussain RGraham UElder ANedergaard M Air pollution, glymphatic impairment, and Alzheimer's disease.; Trends in neurosciences. 2023 Sep 28. Gan YHolstein-Rønsbo SNedergaard MBoster KASThomas JHKelley DH Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism.; Journal of the Royal Society, Interface; Vol 20(206), pp. 20230288. 2023 Sep 20. Takasugi MOhtani NTakemura KEmmrich SZakusilo FTYoshida YKutsukake NMariani JNWindrem MSChandler-Militello DGoldman SASatoh JIto SSeluanov AGorbunova V CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance.; Cell reports; Vol 42(9), pp. 113130. 2023 Sep 13. Holstein-Rønsbo SGan YGiannetto MJRasmussen MKSigurdsson BBeinlich FRMRose LUntiet VHablitz LMKelley DHNedergaard M Publisher Correction: Glymphatic influx and clearance are accelerated by neurovascular coupling.; Nature neuroscience. 2023 Sep 04. Ozawa KNagao MKonno AIwai YVittani MKusk PMishima THirai HNedergaard MHirase H Astrocytic GPCR-Induced Ca2+ Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes.; International journal of molecular sciences; Vol 24(17). 2023 Sep 02. Staudt MShalgunov VNedergaard MHerth MM Development of 11 C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species.; Journal of labelled compounds & radiopharmaceuticals. 2023 Aug 31. Andersen MTsopanidou ARadovanovic TCompere VNHauglund NNedergaard MKjaerby C Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep.; Bio-protocol; Vol 13(15), pp. e4734. 2023 Aug 05. Kim DGan YNedergaard MKelley DHTithof J Image Analysis Techniques for In Vivo Quantification of Cerebrospinal Fluid Flow.; bioRxiv : the preprint server for biology. 2023 Jul 24. Miyakoshi LMStæger FFLi QPan CXie LKang HPavan CDang JSun QErtürk ANedergaard M The state of brain activity modulates cerebrospinal fluid transport.; Progress in neurobiology. 2023 Jul 21. Vieira RMariani JNHuynh NPTStephensen HJTSolly RTate ASchanz SCotrupi NMousaei MSporring JBenraiss AGoldman SA Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain.; Nature biotechnology. 2023 Jul 17. Raicevic NForer JMLadrón-de-Guevara ADu TNedergaard MKelley DHBoster K Sizes and shapes of perivascular spaces surrounding murine pial arteries.; Fluids and barriers of the CNS; Vol 20(1), pp. 56. 2023 Jul 17. Bork PARLadrón-de-Guevara AChristensen AHJensen KHNedergaard MBohr T Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow.; Journal of the Royal Society, Interface; Vol 20(204), pp. 20230050. 2023 Jul 12. Vittani MKnak PAGFukuda MNagao MWang XKjaerby CKonno AHirai HNedergaard MHirase H Virally induced CRISPR/Cas9-based knock-in of fluorescent albumin allows long-term visualization of cerebral circulation in infant and adult mice.; bioRxiv : the preprint server for biology. 2023 Jul 10. Mathiesen BKMiyakoshi LMCederroth CRTserga EVersteegh CBork PARHauglund NLGomolka RSMori YEdvall NKRouse SMøllgård KHolt JRNedergaard MCanlon B Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice.; Science translational medicine; Vol 15(702), pp. eabq3916. 2023 Jun 28. Villanueva CBStephensen HJTMokso RBenraiss ASporring JGoldman SA Astrocytic engagement of the corticostriatal synaptic cleft is disrupted in a mouse model of Huntington's disease.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(24), pp. e2210719120. 2023 Jun 06. Hirase HNedergaard M Locomotion Induces Fundamentally Different Patterns of Ca2+ Signaling in Astrocytes and Neurons.; Function (Oxford, England); Vol 4(4), pp. zqad028. 2023 Jun 05. Holstein-Rønsbo SGan YGiannetto MJRasmussen MKSigurdsson BBeinlich FRMRose LUntiet VHablitz LMKelley DHNedergaard M Glymphatic influx and clearance are accelerated by neurovascular coupling.; Nature neuroscience. 2023 Jun 01. Raizen DMMullington JAnaclet CClarke GCritchley HDantzer RDavis RDrew KLFessel JFuller PMGibson EMHarrington MLipkin WIKlerman EBKlimas NKomaroff ALKoroshetz WKrupp LKuppuswamy ALasselin JLewis LDMagistretti PJMatos HYMiaskowski CMiller AHNath ANedergaard MOpp MRRitchie MDRogulja DRolls ASalamone JDSaper CWhittemore VWylie GYounger JZee PCHeller HC Beyond the Symptom: The Biology of Fatigue.; Sleep. 2023 May 24. Stogsdill JAHarwell CCGoldman SA Astrocytes as master modulators of neural networks: Synaptic functions and disease-associated dysfunction of astrocytes.; Annals of the New York Academy of Sciences. 2023 May 23. Agarwal NLewis LDHirschler LRivera LRNaganawa SLevendovszky SRRingstad GKlarica MWardlaw JIadecola CHawkes CCarare ROWells JBakker ENTPKurtcuoglu VBilston LNedergaard MMori YStoodley MAlperin Nde Leon Mvan Osch MJP Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome.; Journal of magnetic resonance imaging : JMRI. 2023 May 04. Kjaerby CAndersen MHauglund NUntiet VDall CDing FHirase HNedergaard M Reply to: 'Do all norepinephrine surges disrupt sleep?'.; Nature neuroscience. 2023 Apr 20. Untiet VBeinlich FRMKusk PKang NLadrón-de-Guevara ASong WKjaerby CAndersen MHauglund NBojarowska ZSigurdsson BDeng SHirase HPetersen NCVerkhratsky ANedergaard M Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice.; Nature communications; Vol 14(1), pp. 1871. 2023 Apr 04. Parka AVolbracht CHall BBastlund JFNedergaard MLaursen BBotta PSotty F Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model.; Journal of Alzheimer's disease : JAD. 2023 Mar 31. Ge GRRolland JPSong WNedergaard MParker KJ Fluid compartments influence elastography of the aging mouse brain.; Physics in medicine and biology. 2023 Mar 30. Boster KASCai SLadrón-de-Guevara ASun JZheng XDu TThomas JHNedergaard MKarniadakis GEKelley DH Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows.; Proceedings of the National Academy of Sciences of the United States of America; Vol 120(14), pp. e2217744120. 2023 Mar 29. Delle CCankar NDigebjerg Holgersson CHvorup Knudsen HSchiøler Nielsen EKjaerby CMori YNedergaard MWeikop P Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice.; Scientific reports; Vol 13(1), pp. 4137. 2023 Mar 13. Khakh BSGoldman SA Astrocytic contributions to Huntington's disease pathophysiology.; Annals of the New York Academy of Sciences; Vol 1522(1), pp. 42-59. 2023 Mar 02. Sigurdsson BHauglund NLLilius TOMogensen FLMortensen KNBeschorner NKlinger LBærentzen SLRosenholm MPShalgunov VHerth MMori YNedergaard M A SPECT-based method for dynamic imaging of the glymphatic system in rats.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023 Feb 21. Raicevic NForer JMLadron-de-Guevara ADu TNedergaard MKelley DHBoster KAS Sizes and Shapes of Perivascular Spaces Surrounding Murine Pial Arteries.; Research square. 2023 Feb 17. Gomolka RSHablitz LMMestre HGiannetto MDu THauglund NLXie LPeng WMartinez PMNedergaard MMori Y Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation.; eLife; Vol 12. 2023 Feb 09. Plá VBitsika SGiannetto MLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM - a 4th meningeal membrane.; Research square. 2023 Jan 31. Lilius TOMortensen KNDeville CLohela TJStæger FFSigurdsson BFiordaliso EMRosenholm MKamphuis CBeekman FJJensen AINedergaard M Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles.; Journal of controlled release : official journal of the Controlled Release Society. 2023 Jan 30. Plá VBitsika SGiannetto MLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM - a 4 th meningeal membrane.; bioRxiv : the preprint server for biology. 2023 Jan 28. Nasu YAggarwal ALe GNTVo CTKambe YWang XBeinlich FRMLee ABRam TRWang FGorzo KAKamijo YBoisvert MNishinami SKawamura GOzawa TToda HGordon GRGe SHirase HNedergaard MPaquet MEDrobizhev MPodgorski KCampbell RE Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging.; Nature communications; Vol 14(1), pp. 6598. 2023 Jan 27. Esmail TNedergaard MBeinlich FRM Protocol to study molecule exchange between venous blood and CSF in live mice using transcranial bioluminescence imaging.; STAR protocols; Vol 4(4), pp. 102652. 2023 Jan 25. Parka ADegel CDreyer JRichter UHall BBastlund JFLaursen BNedergaard MSotty FBotta P Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model.; Neurobiology of disease; Vol 178, pp. 106012. 2023 Jan 23. Hussain RTithof JWang WCheetham-West ASong WPeng WSigurdsson BKim DSun QPeng SPlá VKelley DHHirase HCastorena-Gonzalez JAWeikop PGoldman SADavis MJNedergaard M Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema.; Nature. 2023 Jan 15. Plá VBitsika SGiannetto MJLadron-de-Guevara AGahn-Martinez DMori YNedergaard MMøllgård K Structural characterization of SLYM-a 4th meningeal membrane.; Fluids and barriers of the CNS; Vol 20(1), pp. 93. 2023 Jan 14. Wang XDelle CPeng WPlá VGiannetto MKusk PSigurdsson BSakurai SSweeney ASun QDu TLibby RTNedergaard M Age- and glaucoma-induced changes to the ocular glymphatic system.; Neurobiology of disease. 2023 Jan 11. Møllgård KBeinlich FRMKusk PMiyakoshi LMDelle CPlá VHauglund NLEsmail TRasmussen MKGomolka RSMori YNedergaard M A mesothelium divides the subarachnoid space into functional compartments.; Science (New York, N.Y.); Vol 379(6627), pp. 84-88. 2023 Jan 05. Ge GRSong WNedergaard MRolland JPParker KJ Corrigendum: Theory of sleep/wake cycles affecting brain elastography (2022Phys. Med. Biol.67225013).; Physics in medicine and biology; Vol 68(21). 2023 Jan 02. Helakari HJärvelä MVäyrynen TTuunanen JPiispala JKallio MEbrahimi SMPoltojainen VKananen JElabasy AHuotari NRaitamaa LTuovinen TKorhonen VNedergaard MKiviniemi V Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations.; Frontiers in neuroscience; Vol 17, pp. 1275184. 2023 Jan 01. Plá VNedergaard M An unnoticed player overseeing CSF flux.; Nature cardiovascular research; Vol 1(12), pp. 1114-1115. 2022 Dec. Lilius TORosenholm MKlinger LMortensen KNSigurdsson BMogensen FLHauglund NLNielsen MSNRantamäki TNedergaard M SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline.; iScience; Vol 25(10), pp. 105250. 2022 Sep 29. Lopes van den Broek SShalgunov VGarcía Vázquez RBeschorner NBidesi NSRNedergaard MKnudsen GMSehlin DSyvänen SHerth MM Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible?; Pharmaceuticals (Basel, Switzerland); Vol 15(10). 2022 Sep 27. Lopes van den Broek SSehlin DAndersen JVAldana BIBeschörner NNedergaard MKnudsen GMSyvänen SHerth MM The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier.; Frontiers in nuclear medicine (Lausanne, Switzerland); Vol 2, pp. 1001722. 2022 Sep 23. Alvarado AGTessema KMuthukrishnan SDSober MKawaguchi RLaks DRBhaduri ASwarup VNathanson DAGeschwind DHGoldman SAKornblum HI Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.; Cancer research communications; Vol 2(9), pp. 1049-1060. 2022 Sep 22. Wang XDelle CAsiminas AAkther SVittani MBrøgger PKusk PVo CTRadovanovic TKonno AHirai HFukuda MWeikop PGoldman SANedergaard MHirase H Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation.; Cell reports methods; Vol 2(10), pp. 100302. 2022 Sep 21. Carlsen EMMNedergaard MRasmussen RN Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice.; STAR protocols; Vol 3(4), pp. 101701. 2022 Sep 14. Wu SYWen YSerre NBCLaursen CCHDietz AGTaylor BRDrobizhev MMolina RSAggarwal ARancic VBecker MBallanyi KPodgorski KHirase HNedergaard MFendrych MLemieux MJEberl DFKay ARCampbell REShen Y A sensitive and specific genetically encoded potassium ion biosensor for in vivo applications across the tree of life.; PLoS biology; Vol 20(9), pp. e3001772. 2022 Sep 06. Benraiss AMariani JNTate AMadsen PMClark KMWelle KASolly RCapellano LBentley KChandler-Militello DGoldman SA A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice.; Cell reports; Vol 40(9), pp. 111291. 2022 Aug 30. Giannetto MJHablitz LM Reading to the end(foot): translational readthrough of AQP4 increases amyloid-β clearance.; Brain : a journal of neurology. 2022 Aug 25. Bohr THjorth PGHolst SCHrabětová SKiviniemi VLilius TLundgaard IMardal KAMartens EAMori YNägerl UVNicholson CTannenbaum AThomas JHTithof JBenveniste HIliff JJKelley DHNedergaard M The glymphatic system: Current understanding and modeling.; iScience; Vol 25(9), pp. 104987. 2022 Aug 20. Lohela TJLilius TONedergaard M The glymphatic system: implications for drugs for central nervous system diseases.; Nature reviews. Drug discovery. 2022 Aug 10. Zubair HShamas SUllah HNabi GHuma TUllah RHussain RShahab M Morphometric and Myelin Basic Protein Expression Changes in Arcuate Nucleus Kisspeptin Neurons Underlie Activation of Hypothalamic Pituitary Gonadal-axis in Monkeys (Macaca Mulatta) during the Breeding Season.; Endocrine research; Vol 47(3-4), pp. 113-123. 2022 Jul 22. Wostyn PMader THGibson CRNedergaard M The effect of long-duration spaceflight on perivascular spaces within the brain.; Proceedings of the National Academy of Sciences of the United States of America; Vol 119(32), pp. e2207724119. 2022 Jul 18. Kjaerby CAndersen MHauglund NUntiet VDall CSigurdsson BDing FFeng JLi YWeikop PHirase HNedergaard M Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine.; Nature neuroscience. 2022 Jul 07. Mestre HVerma NGreene TDLin LALadron-de-Guevara ASweeney AMLiu GThomas VKGalloway CAde Mesy Bentley KLNedergaard MMehta RI Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer's disease.; Nature communications; Vol 13(1). 2022 Jul 06. Rosser AEBusse MEGray WPBadin RAPerrier ALWheelock VCozzi EMartin UPSalado-Manzano CMills LJDrew CGoldman SACanals JMThompson LM Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder.; Brain : a journal of neurology; Vol 145(5). 2022 Jun 03. Tithof JBoster KASBork PARNedergaard MThomas JHKelley DH A network model of glymphatic flow under different experimentally-motivated parametric scenarios.; iScience; Vol 25(5). 2022 May 20. Kananen JJärvelä MKorhonen VTuovinen THuotari NRaitamaa LHelakari HVäyrynen TRaatikainen VNedergaard MAnsakorpi HJacobs JLeVan PKiviniemi V Increased interictal synchronicity of respiratory related brain pulsations in epilepsy.; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2022 May 14. Ladrón-de-Guevara AShang JKNedergaard MKelley DH Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment.; Journal of theoretical biology. 2022 Mar 23. Monai HKoketsu SShinohara YUeki TKusk PHauglund NLSamson AJNedergaard MHirase H Author Correction: Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization.; Scientific reports; Vol 12(1). 2022 Mar 18. Beaman EEBonde ANUlv Larsen SMOzenne BLohela TJNedergaard MGíslason GHKnudsen GMHolst SC Blood-brain barrier permeable β-blockers linked to lower risk of Alzheimer's disease in hypertension.; Brain : a journal of neurology. 2022 Feb 23. Helakari HKorhonen VHolst SCPiispala JKallio MVäyrynen THuotari NRaitamaa LTuunanen JKananen JJärvelä MTuovinen TRaatikainen VBorchardt VKinnunen HNedergaard MKiviniemi V Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations.; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022 Feb 07. Ge GRSong WNedergaard MRolland JPParker KJ Theory of sleep/wake cycles affecting brain elastography.; Physics in medicine and biology. 2022 Jan 27. Feng WZhang YDing SChen SWang TWang ZZou YSheng CChen YPang YMarshall CShi JNedergaard MLi QXiao M B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35.; Brain, behavior, and immunity; Vol 108, pp. 16-31. 2022 Jan 24. Persson NDÅUusalo PNedergaard MLohela TJLilius TO Could dexmedetomidine be repurposed as a glymphatic enhancer?; Trends in pharmacological sciences. 2022 Jan 21. Muthukrishnan SDKawaguchi RNair PPrasad RQin YJohnson MWang QVanderVeer-Harris NPham AAlvarado AGCondro MCGao FGau RCastro MGLowenstein PRDeb AHinman JDPajonk FBurns TCGoldman SAGeschwind DHKornblum HI P300 promotes tumor recurrence by regulating radiation-induced conversion of glioma stem cells to vascular-like cells.; Nature communications; Vol 13(1), pp. 6202. 2022 Jan 19. Ghochani YMuthukrishnan SDSohrabi AKawaguchi RCondro MCBastola SGao FQin YMottahedeh JIruela-Arispe MLRao NLaks DRLiau LMMathern GWGoldman SACarmichael STNakano ICoppola GSeidlits SKKornblum HI A molecular interactome of the glioblastoma perivascular niche reveals integrin binding sialoprotein as a mediator of tumor cell migration.; Cell reports; Vol 41(3), pp. 111511. 2022 Jan 18. 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