URMC / Center for Vaccine Biology & Immunology / Research / Publications Publications Knudsen-Clark AMMwangi DCazarin JMorris KBaker CHablitz LMMcCall MNKim MAltman BJ Circadian rhythms of macrophages are altered by the acidic tumor microenvironment.; EMBO reports. 2024 Oct 16. Dahal AHong YMathew JSGeber AEckl SRenner SSailer CJRyan ATMir SLim KLinehan DCGerber SAKim M Platelet-activating factor (PAF) promotes immunosuppressive neutrophil differentiation within tumors.; Proceedings of the National Academy of Sciences of the United States of America; Vol 121(35), pp. e2406748121. 2024 Aug 23. Ross TLNa RAu-Yeung GDeFazio AFriedlander MSivakumaran TLivingstone KNagle CMO'Neill HWilliams MWebb PMBeesley VL Are exercise and sitting time during chemotherapy for ovarian cancer associated with treatment-related side-effects, chemotherapy completion and survival?; Gynecologic oncology; Vol 190, pp. 53-61. 2024 Aug 14. Bender WZhang YCorbett AChu CGrier AWang LQiu XMcCall MNTopham DJWalsh EEMariani TJScheuermann RCaserta MTAnderson CS Association of disease severity and genetic variation during primary Respiratory Syncytial Virus infections.; BMC medical genomics; Vol 17(1), pp. 165. 2024 Jun 19. Caillier AOleksyn DFowell DJMiller JOakes PW T cells use focal adhesions to pull themselves through confined environments.; The Journal of cell biology; Vol 223(10). 2024 Jun 18. Mosmann TRRebhahn JADe Rosa SCKeefer MCMcElrath MJRouphael NGPantaleo GGilbert PBCorey LKobie JJThakar J SWIFT clustering analysis of intracellular cytokine staining flow cytometry data of the HVTN 105 vaccine trial reveals high frequencies of HIV-specific CD4+ T cell responses and associations with humoral responses.; Frontiers in immunology; Vol 15, pp. 1347926. 2024 Jun 06. Ryan ATDahal AMir SKim MLim K Real-Time In Vitro Migration Assay for Primary Murine CD8+ T Cells.; Journal of visualized experiments : JoVE. 2024 May 24. Ciambella CWitt HDickinson CMSmith MLCoburn NMessina NHeffernan DSKim MReichner JS Inhibition of Integrin VLA-3 and Tetraspanin CD151 Protects Against Neutrophil-Mediated Endothelial Damage.; Shock (Augusta, Ga.). 2024 May 23. Richards KAChangrob SThomas PGWilson PCSant AJ Lack of memory recall in human CD4 T cells elicited by the first encounter with SARS-CoV-2.; iScience; Vol 27(6), pp. 109992. 2024 May 17. Ryan ATKim MLim K Immune Cell Migration to Cancer.; Cells; Vol 13(10). 2024 May 16. Mosmann TRMcMichael AJLeVert AMcCauley JWAlmond JW Opportunities and challenges for T cell-based influenza vaccines.; Nature reviews. Immunology. 2024 May 02. Hong SCHong CRKim MKang YJJung YHPark KMChoi JChang PS Process optimization for microfluidic preparation of liposomes using food-grade components.; Food chemistry; Vol 451, pp. 139437. 2024 Apr 24. Lin MYNam EShih RMShafer ABouren AAyala Ceja MHarris CKhericha MVo KHKim MTseng CHChen YY Self-regulating CAR-T cells modulate cytokine release syndrome in adoptive T-cell therapy.; The Journal of experimental medicine; Vol 221(6). 2024 Apr 12. Li CTure SKNieves-Lopez BBlick-Nitko SKMaurya PLivada ACStahl TJKim MPietropaoli APMorrell CN Thrombocytopenia Independently Leads to Changes in Monocyte Immune Function.; Circulation research. 2024 Mar 08. White CLGlover MAGandhapudi SKRichards KASant AJ Flublok Quadrivalent Vaccine Adjuvanted with R-DOTAP Elicits a Robust and Multifunctional CD4 T Cell Response That Is of Greater Magnitude and Functional Diversity Than Conventional Adjuvant Systems.; Vaccines; Vol 12(3). 2024 Mar 07. Martin ATGiri SSafronova AEliseeva SIKwok SFYarovinsky F Parasite-induced IFN-γ regulates host defense via CD115 and mTOR-dependent mechanism of tissue-resident macrophage death.; PLoS pathogens; Vol 20(2), pp. e1011502. 2024 Feb 20. Knudsen-Clark AMMwangi DCazarin JHablitz LMKim MAltman BJ Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment.; bioRxiv : the preprint server for biology. 2024 Feb 16. Park SColville MJPaek JHShurer CRSingh ASecor EJSailer CJHuang LTKuo JCGoudge MCSu JKim MDeLisa MPNeelamegham SLammerding JZipfel WRFischbach CReesink HLPaszek MJ Immunoengineering can overcome the glycocalyx armour of cancer cells.; Nature materials. 2024 Feb 15. Piepenbrink MOladunni FNogales AKhalil AMFitzgerald THilimire TABasu MFucile CTopham DJRosenberg AFMartinez-Sobrido LKobie JJ Correction for Piepenbrink et al., "Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies".; Microbiology spectrum. 2024 Jan 30. Sportiello MPoindexter AReilly ECGeber ALambert Emo KJones TNTopham DJ Mouse Memory CD8 T Cell Subsets Defined by Tissue-Resident Memory Integrin Expression Exhibit Distinct Metabolic Profiles.; ImmunoHorizons; Vol 7(10), pp. 652-669. 2023 Oct 01. Brady MTLaniewski NStrawderman MChu CCKanagaiah PSangster MYTopham DJFriedberg JWZent CS Long-term results of vaccination with adjuvanted recombinant varicella zoster glycoprotein E during initial Bruton tyrosine kinase inhibitors therapy for chronic lymphocytic leukemia or lymphoplasmacytic lymphoma.; American journal of hematology. 2023 Jul 23. Piepenbrink MOladunni FNogales AKhalil AMFitzgerald TBasu MFucile CTopham DJRosenberg AFMartinez-Sobrido LKobie JJ Highly Cross-Reactive and Protective Influenza A Virus H3N2 Hemagglutinin- and Neuraminidase-Specific Human Monoclonal Antibodies.; Microbiology spectrum. 2023 Jun 15. Sailer CJHong YDahal ARyan ATMir SGerber SAReagan PMKim M PD-1Hi CAR-T cells provide superior protection against solid tumors.; Frontiers in immunology; Vol 14, pp. 1187850. 2023 Jun 14. Simpson ELSchlievert PMYoshida TLussier SBoguniewicz MHata TFuxench ZDe Benedetto AOng PYKo JCalatroni ARudman Spergel AKPlaut MQuataert SAKilgore SHPeterson LGill ALDavid GMosmann TGill SRLeung DYMBeck LA Rapid Reduction in Staphylococcus aureus in Atopic Dermatitis Subjects Following Dupilumab Treatment.; The Journal of allergy and clinical immunology. 2023 Jun 12. Waugh RELomakina EAmitrano AKim M Activation effects on the physical characteristics of T lymphocytes.; Frontiers in bioengineering and biotechnology; Vol 11, pp. 1175570. 2023 May 15. Li CTure SKNieves-Lopez BBlick-Nitko SKMaurya PLivada ACStahl TJKim MPietropaoli APMorrell CN Thrombocytopenia Independently Leads to Monocyte Immune Dysfunction.; bioRxiv : the preprint server for biology. 2023 May 12. Hong YWalling BLKim HRSerratelli WSLozada JRSailer CJAmitrano AMLim KMongre RKKim KDCapece TLomakina EBReilly NSVo KGerber SAFan TCYu ALOakes PWWaugh REJun CDReagan PMKim M ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.; Nature immunology. 2023 Apr 17. Moore JEBloom PCChu CCBruno JEHerne CABaran AMQuataert SAMosmann TRTaylor RPWallace DSElliott MRBarr PMZent CS Rituximab induced cytokine release with high serum IP-10 (CXCL10) concentrations is associated with infusion reactions.; Leukemia research; Vol 129, pp. 107072. 2023 Mar 29. Henson TRRichards KAGandhapudi SKWoodward JGSant AJ R-DOTAP Cationic Lipid Nanoparticles Outperform Squalene-Based Adjuvant Systems in Elicitation of CD4 T Cells after Recombinant Influenza Hemagglutinin Vaccination.; Viruses; Vol 15(2). 2023 Feb 15. Villamayor LRivero VLópez-García DTopham DJMartínez-Sobrido LNogales ADeDiego ML Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation.; Frontiers in immunology; Vol 14, pp. 1105309. 2023 Jan 30. Amitrano AMKim M Metabolic Challenges in Anticancer CD8 T Cell Functions.; Immune network; Vol 23(1), pp. e9. 2023 Jan 27. Caillier AOleksyn DFowell DJMiller JOakes PW T cells Use Focal Adhesions to Pull Themselves Through Confined Environments.; bioRxiv : the preprint server for biology. 2023 Jan 19. Wang MSHu YSanchez EEXie XRoy NHde Jesus MWiner BYZale EAJin WSachar CLee JHHong YKim MKam LCSalaita KHuse M Author Correction: Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity.; Nature communications; Vol 14(1), pp. 8401. 2023 Jan 18. Sharma KKDiltz MALincoln TAlbuquerque ERRomanski LM Neuronal Population Encoding of Identity in Primate Prefrontal Cortex.; The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023 Jan 14. Xie CRen YWeeks JRainbolt JMark Kenney HXue TAllen FShu YTay AJHLekkala SYeh SAMuthukrishnan GGill ALGill SRKim MKates SLSchwarz EM Longitudinal Intravital Imaging of the Bone Marrow (LIMB) for Analysis of the Race for the Surface in a Murine Osteomyelitis Model.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2023 Jan 09. Sant AJStern LJ Editorial overview: The life and times of peptide-MHC.; Current opinion in immunology; Vol 78, pp. 102244. 2022 Sep 28. Sant AJWilson PC Learning from our differences.; Nature immunology. 2022 Sep 27. Yu JTycksen EYang WMariani TJBhattacharya SFalsey ARTopham DJStorch GA Use of Host Response to Refine the Diagnosis of Group A Streptococcal Pharyngitis.; Journal of the Pediatric Infectious Diseases Society. 2022 Sep 25. Trzeciak AMongre RKKim MRLim KMadero RAParkhurst CNPietropaoli APKim M Neutrophil heterogeneity in complement C1q expression associated with sepsis mortality.; Frontiers in immunology; Vol 13, pp. 965305. 2022 Aug 02. Wang MSHu YSanchez EEXie XRoy NHde Jesus MWiner BYZale EAJin WSachar CLee JHHong YKim MKam LCSalaita KHuse M Mechanically active integrins target lytic secretion at the immune synapse to facilitate cellular cytotoxicity.; Nature communications; Vol 13(1). 2022 Jun 09. McDavid ALaniewski NGrier AGill ALKessler HAHuyck HCarbonell EHolden-Wiltse JBandyopadhyay SCarnahan JDylag AMTopham DJFalsey ARCaserta MTPryhuber GSGill SRScheible KM Aberrant newborn T cell and microbiota developmental trajectories predict respiratory compromise during infancy.; iScience; Vol 25(4). 2022 Apr 15. Moritzky SARichards KAGlover MAKrammer FChaves FATopham DJBranche ANayak JLSant AJ The negative effect of pre-existing immunity on influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history.; The Journal of infectious diseases. 2022 Feb 24. Jankovic DCiucci TCoffman RLCoquet JMLe Gros GMosmann TRSher ARonchese F Comment on: Repositioning TH cell polarization from single cytokines to complex help.; Nature immunology. 2022 Feb 21. Rattan AWhite CLNelson SEismann MPadilla-Quirarte HGlover MADileepan TMarathe BMGovorkova EAWebby RJRichards KASant AJ Development of a Mouse Model to Explore CD4 T Cell Specificity, Phenotype, and Recruitment to the Lung after Influenza B Infection.; Pathogens (Basel, Switzerland); Vol 11(2). 2022 Feb 15. Embong AKNguyen-Contant PWang JKanagaiah PChaves FAFitzgerald TFZhou QKosoy GBranche ARMiller BLZand MSSangster MYTopham DJ Formation and Expansion of Memory B Cells against Coronavirus in Acutely Infected COVID-19 Individuals.; Pathogens (Basel, Switzerland); Vol 11(2). 2022 Jan 29. Kim MLi SKong DSSong YEPark SYKim HIJae JChung IKim JR Polydopamine/polypyrrole-modified graphite felt enhances biocompatibility for electroactive bacteria and power density of microbial fuel cell.; Chemosphere. 2022 Jan 28. Nelson SARichards KAGlover MAChaves FACrank MCGraham BSKanekiyo MSant AJ CD4 T cell epitope abundance in ferritin core potentiates responses to hemagglutinin nanoparticle vaccines.; NPJ vaccines; Vol 7(1), pp. 124. 2022 Jan 26. Richards KALavery CKeller GLJMiller JBaker BMSant AJ A previously unappreciated polymorphism in the beta chain of I-As expressed in autoimmunity-prone SJL mice: Combined impact on antibody, CD4 T cell recognition and MHC class II dimer structural stability.; Molecular immunology; Vol 143. 2022 Jan 04. Livingstone AM Wanted: A political sociology of race in Canada.; Canadian review of sociology = Revue canadienne de sociologie. 2022 Jan 02. Veazey JMWong GSEliseeva SISmyth TRChapman TJLim KKim MGeoras SN Protein kinase D3 promotes neutrophil migration during viral infection.; Immunology and cell biology. 2022 Jan 01. McCall MNChu CYWang LBenoodt LThakar JCorbett AHolden-Wiltse JSlaunwhite CGrier AGill SRFalsey ARTopham DJCaserta MTWalsh EEQiu XMariani TJ A systems genomics approach uncovers molecular associates of RSV severity.; PLoS computational biology; Vol 17(12). 2021 Dec 28. Young BESeppo AEDiaz NRosen-Carole CNowak-Wegrzyn ACruz Vasquez JMFerri-Huerta RNguyen-Contant PFitzgerald TSangster MYTopham DJJärvinen KM Association of Human Milk Antibody Induction, Persistence, and Neutralizing Capacity With SARS-CoV-2 Infection vs mRNA Vaccination.; JAMA pediatrics. 2021 Nov 10. Yee Mon KJZhu HDaly CWPVu LTSmith NLPatel RTopham DJScheible KJambo KLe MTNRudd BDGrimson A MicroRNA-29 specifies age-related differences in the CD8+ T cell immune response.; Cell reports; Vol 37(6). 2021 Nov 09. Araujo ASafronova ABurger ELópez-Yglesias AGiri SCamanzo ETMartin ATGrivennikov SYarovinsky F IFN-γ mediates Paneth cell death via suppression of mTOR.; eLife; Vol 10. 2021 Oct 11. Prizant HPatil NNegatu SBala NMcGurk ALeddon SAHughson AMcRae TDGao YRLivingstone AMGroom JRLuster ADFowell DJ CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter.; Cell reports; Vol 36(6). 2021 Aug 10. Ghosh SKPark JNa SKim MPKo H A Fully Biodegradable Ferroelectric Skin Sensor from Edible Porcine Skin Gelatine.; Advanced science (Weinheim, Baden-Wurttemberg, Germany); Vol 8(13). 2021 Jul. Nelson SADileepan TRasley AJenkins MKFischer NOSant AJ Intranasal nanoparticle vaccination elicits a persistent, polyfunctional CD4 T cell response in the murine lung specific for a highly conserved influenza antigen that are sufficient to mediate protection from influenza virus challenge.; Journal of virology. 2021 Jun 02. Qin SSHan BJWilliams AJackson KMJewell RChacon ACLord EMLinehan DCKim MReuben AGerber SAPrieto PA Intertumoral Genetic Heterogeneity Generates Distinct Tumor Microenvironments in a Novel Murine Synchronous Melanoma Model.; Cancers; Vol 13(10). 2021 May 11. Nguyen-Contant PSangster MYTopham DJ Squalene-Based Influenza Vaccine Adjuvants and Their Impact on the Hemagglutinin-Specific B Cell Response.; Pathogens (Basel, Switzerland); Vol 10(3). 2021 Mar 17. Wang LChu CYMcCall MNSlaunwhite CHolden-Wiltse JCorbett AFalsey ARTopham DJCaserta MTMariani TJWalsh EEQiu X Airway gene-expression classifiers for respiratory syncytial virus (RSV) disease severity in infants.; BMC medical genomics; Vol 14(1). 2021 Feb 25. Fowell DJKim M The spatio-temporal control of effector T cell migration.; Nature reviews. Immunology. 2021 Feb 24. Pace RMWilliams JEJärvinen KMBelfort MBPace CDWLackey KAGogel ACNguyen-Contant PKanagaiah PFitzgerald TFerri RYoung BRosen-Carole CDiaz NMeehan CLCaffé BSangster MYTopham DMcGuire MASeppo AMcGuire MK Characterization of SARS-CoV-2 RNA, Antibodies, and Neutralizing Capacity in Milk Produced by Women with COVID-19.; mBio; Vol 12(1). 2021 Feb 09. Richards KAGlover MCrawford JCThomas PWhite CSant AJ Circulating CD4 T cells elicited by endemic coronaviruses display vast disparities in abundance and functional potential linked to both antigen specificity and age.; The Journal of infectious diseases. 2021 Feb 08. López-Yglesias AHBurger ECamanzo EMartin ATAraujo AMKwok SFYarovinsky F T-bet-dependent ILC1- and NK cell-derived IFN-γ mediates cDC1-dependent host resistance against Toxoplasma gondii.; PLoS pathogens; Vol 17(1). 2021 Jan 19. Lorbach JNFitzgerald TNolan CNolting JMTreanor JJTopham DJBowman AS Gaps in Serologic Immunity against Contemporary Swine-Origin Influenza A Viruses among Healthy Individuals in the United States.; Viruses; Vol 13(1). 2021 Jan 18. Amitrano AMBerry BJLim KKim KDWaugh REWojtovich APKim M Optical Control of CD8+ T Cell Metabolism and Effector Functions.; Frontiers in immunology; Vol 12. 2021. Reilly ECSportiello MEmo KLAmitrano AMJha RKumar ABRLaniewski NGYang HKim MTopham DJ CD49a Identifies Polyfunctional Memory CD8 T Cell Subsets that Persist in the Lungs After Influenza Infection.; Frontiers in immunology; Vol 12. 2021. Nelson SASant AJ Potentiating Lung Mucosal Immunity Through Intranasal Vaccination.; Frontiers in immunology; Vol 12. 2021. Nguyen-Contant PEmbong AKTopham DJSangster MY Analysis of Antigen-Specific Human Memory B Cell Populations Based on In Vitro Polyclonal Stimulation.; Current protocols in immunology; Vol 131(1). 2020 Dec. Bares AJMejooli MAPender MALeddon SATilley SLin KDong JKim MFowell DJNishimura NSchaffer CB Hyperspectral multiphoton microscopy for in vivo visualization of multiple, spectrally overlapped fluorescent labels.; Optica; Vol 7(11). 2020 Nov 20. Alon RSportiello MKozlovski SKumar AReilly ECZarbock AGarbi NTopham DJ Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19.; Nature reviews. Immunology. 2020 Nov 19. Zent CSBrady MTDelage CStrawderman MLaniewski NContant PNKanagaiah PSangster MYBarr PMChu CCTopham DJFriedberg JW Short term results of vaccination with adjuvanted recombinant varicella zoster glycoprotein E during initial BTK inhibitor therapy for CLL or lymphoplasmacytic lymphoma.; Leukemia. 2020 Oct 30. Nguyen-Contant PEmbong AKKanagaiah PChaves FAYang HBranche ARTopham DJSangster MY S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit.; mBio; Vol 11(5). 2020 Sep 25. Steiner DJCognetti JSLuta EPKlose AMBucukovski JBryan MRSchmuke JJNguyen-Contant PSangster MYTopham DJMiller BL Array-based analysis of SARS-CoV-2, other coronaviruses, and influenza antibodies in convalescent COVID-19 patients.; Biosensors & bioelectronics; Vol 169. 2020 Sep 21. Pace RMWilliams JEJärvinen KMBelfort MBPace CDLackey KAGogel ACNguyen-Contant PKanagaiah PFitzgerald TFerri RYoung BRosen-Carole CDiaz NMeehan CCaffe BSangster MYTopham DJMcGuire MASeppo AMcGuire MK COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity.; medRxiv : the preprint server for health sciences. 2020 Sep 18. Grier AGill ALKessler HACorbett ABandyopadhyay SJava JHolden-Wiltse JFalsey ARTopham DJMariani TJCaserta MTWalsh EEGill SR Temporal Dysbiosis of Infant Nasal Microbiota Relative to Respiratory Syncytial Virus Infection.; The Journal of infectious diseases. 2020 Sep 14. Chu CYQiu XMcCall MNWang LCorbett AHolden-Wiltse JSlaunwhite CGrier AGill SRPryhuber GSFalsey ARTopham DJCaserta MTWalsh EEMariani TJ Airway gene expression correlates of RSV disease severity and microbiome composition in infants.; The Journal of infectious diseases. 2020 Sep 14. Gouma SKim KWeirick MEGumina MEBranche ATopham DJMartin ETMonto ASCobey SHensley SE Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility.; Nature communications; Vol 11(1). 2020 Sep 11. Mai NPrifti VLim KO'Reilly MAKim MHalterman MW Lung SOD3 limits neurovascular reperfusion injury and systemic immune activation following transient global cerebral ischemia.; Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association; Vol 29(9). 2020 Sep. Richards KAMoritzky SShannon IFitzgerald TYang HBranche ATopham DJTreanor JJNayak JSant AJ Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans.; NPJ vaccines; Vol 5(1). 2020 Aug 26. Thakar JQian YBenoodt LRoumanes DQiu XLaniewski NChu CSlaunwhite CWang LMandava AChang IFalsey ARCaserta MTMariani TJScheuermann RHWalsh EETopham DJ Unbiased analysis of peripheral blood mononuclear cells reveals CD4 T cell response to RSV matrix protein.; Vaccine: X; Vol 5. 2020 Aug 07. Lim KKim THTrzeciak AAmitrano AMReilly ECPrizant HFowell DJTopham DJKim M In situ neutrophil efferocytosis shapes T cell immunity to influenza infection.; Nature immunology. 2020 Aug 03. Vom Steeg LGDhakal SWoletsadik YAPark HSMulka KRReilly ECTopham DJKlein SL Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice.; PLoS pathogens; Vol 16(7). 2020 Jul 09. McDavid ACorbett AMDutra JLStraw AGTopham DJPryhuber GSCaserta MTGill SRScheible KMHolden-Wiltse J Eight practices for data management to enable team data science.; Journal of clinical and translational science; Vol 5(1). 2020 Jun 23. Anderson CSSangster MYYang HMariani TJChaudhury STopham DJ Implementing sequence-based antigenic distance calculation into immunological shape space model.; BMC bioinformatics; Vol 21(1). 2020 Jun 19. Reilly ECLambert Emo KBuckley PMReilly NSSmith IChaves FAYang HOakes PWTopham DJ TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection.; Proceedings of the National Academy of Sciences of the United States of America; Vol 117(22). 2020 Jun 02. Trzeciak APietropaoli APKim M Biomarkers and Associated Immune Mechanisms for Early Detection and Therapeutic Management of Sepsis.; Immune network; Vol 20(3). 2020 Jun. Mai NPrifti VKim MHalterman MW Characterization of neutrophil-neuronal co-cultures to investigate mechanisms of post-ischemic immune-mediated neurotoxicity.; Journal of neuroscience methods. 2020 May 20. Rebhahn JAQuataert SASharma GMosmann TR SwiftReg cluster registration automatically reduces flow cytometry data variability including batch effects.; Communications biology; Vol 3(1). 2020 May 07. Meilleur CEMemarnejadian AShivji ANBenoit JMTuffs SWMele TSSingh BDikeakos JDTopham DJMu HHBennink JRMcCormick JKHaeryfar SMM Discordant rearrangement of primary and anamnestic CD8+ T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections.; PLoS pathogens; Vol 16(5). 2020 May. Moore KAOstrowsky JTMehr AJOsterholm MT Influenza response planning for the centers of excellence for influenza research and surveillance: Science preparedness for enhancing global health security.; Influenza and other respiratory viruses. 2020 Apr 19. Topham DJ Serendipity: Reflections on Being Mentored by Dr. Peter Doherty.; Viral immunology; Vol 33(3). 2020 Apr. Martinez-Sobrido LBlanco-Lobo PRodriguez LFitzgerald TZhang HNguyen PAnderson CSHolden-Wiltse JBandyopadhyay SNogales ADeDiego MLWasik BRMiller BLHenry CWilson PCSangster MYTreanor JJTopham DJByrd-Leotis LSteinhauer DACummings RDLuczo JMTompkins SMSakamoto KJones CASteel JLowen ACDanzy STao HFink ALKlein SLWohlgemuth NFenstermacher KJEl Najjar FPekosz ASauer LLewis MKShaw-Saliba KRothman RELiu ZYChen KFParrish CRVoorhees IEHKawaoka YNeumann GChiba SFan SHatta MKong HZhong GWang GUccellini MBGarcía-Sastre APerez DRFerreri LMHerfst SRichard MFouchier RBurke DPattinson DSmith DJMeliopoulos VFreiden PLivingston BSharp BCherry SDib JCYang GRussell CJBarman SWebby RJKrauss SDanner AWoodard KPeiris MPerera RAPMChan MCWGovorkova EAMarathe BMPascua PNQSmith GLi YTThomas PGSchultz-Cherry S Characterizing Emerging Canine H3 Influenza Viruses.; PLoS pathogens; Vol 16(4). 2020 Apr. Tourtelot EQuataert SGlantz JCPerlis LMuthukrishnan GMosmann T Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels.; Vaccine; Vol 38(7). 2020 Feb 11. Berry BJTrewin AJMilliken ASBaldzizhar AAmitrano AMLim YKim MWojtovich AP Optogenetic control of mitochondrial protonmotive force to impact cellular stress resistance.; EMBO reports. 2020 Feb 11. Coombs RSBlank MLEnglish EDAdomako-Ankomah YUrama ISMartin ATYarovinsky FBoyle JP Immediate interferon gamma induction determines murine host compatibility differences between Toxoplasma gondii and Neospora caninum.; Infection and immunity. 2020 Feb 03. Koroleva MBatarse FMoritzky SHenry CChaves FWilson PKrammer FRichards KSant AJ Heterologous viral protein interactions within licensed seasonal influenza virus vaccines.; NPJ vaccines; Vol 5(1). 2020 Jan 10. Emo KReilly ECSportiello MYang HTopham DJ T cell and chemokine receptors differentially control CD8 T cell motility behavior in the infected airways immediately before and after virus clearance in a primary infection.; PloS one; Vol 15(8). 2020. Leddon SAFettis MMAbramo KKelly ROleksyn DMiller J The CD28 Transmembrane Domain Contains an Essential Dimerization Motif.; Frontiers in immunology; Vol 11. 2020. Richards KAMoritzky SShannon IFitzgerald TYang HBranche ATopham DJTreanor JJNayak JSant AJ Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans.; NPJ vaccines; Vol 5. 2020. Veazey JMEliseeva SIHillman SEStiles KSmyth TRMorrissey CETillotson EJTopham DJChapman TJGeoras SN Inhibiting Protein Kinase D Promotes Airway Epithelial Barrier Integrity in Mouse Models of Influenza A Virus Infection.; Frontiers in immunology; Vol 11. 2020. Koroleva MBatarse FMoritzky SHenry CChaves FWilson PKrammer FRichards KSant AJ Heterologous viral protein interactions within licensed seasonal influenza virus vaccines.; NPJ vaccines; Vol 5. 2020. Topham DJDeDiego MLNogales ASangster MYSant A Immunity to Influenza Infection in Humans.; Cold Spring Harbor perspectives in medicine. 2019 Dec 30. Smith ARodriguez LGhouayel MENogales AChamberlain JMSortino KReilly EFeng CTopham DJMartínez-Sobrido LDewhurst S A live-attenuated influenza vaccine (LAIV) elicits enhanced heterologous protection when the internal genes of the vaccine are matched to the challenge virus.; Journal of virology. 2019 Nov 20. Knowlden ZAGRichards KAMoritzky SASant AJ Peptide Epitope Hot Spots of CD4 T Cell Recognition Within Influenza Hemagglutinin During the Primary Response to Infection.; Pathogens (Basel, Switzerland); Vol 8(4). 2019 Nov 05. DeDiego MLMartinez-Sobrido LTopham DJ Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses.; Journal of virology; Vol 93(21). 2019 Nov 01. Henry CPalm AEUtset HAHuang MHo IYZheng NYFitzgerald TNeu KEChen YQKrammer FTreanor JJSant AJTopham DJWilson PC Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study.; Journal of virology; Vol 93(21). 2019 Nov 01. Wu EKHenkes ZIMcGowan BBell RDVelez MJLivingstone AMRitchlin CTSchwarz EMRahimi H TNF-Induced Interstitial Lung Disease in a Murine Arthritis Model: Accumulation of Activated Monocytes, Conventional Dendritic Cells, and CD21+/CD23- B Cell Follicles Is Prevented with Anti-TNF Therapy.; Journal of immunology (Baltimore, Md. : 1950). 2019 Oct 28. Topham DJReilly ECEmo KLSportiello M Formation and Maintenance of Tissue Resident Memory CD8+ T Cells after Viral Infection.; Pathogens (Basel, Switzerland); Vol 8(4). 2019 Oct 18. Trzeciak ALerman YVKim THKim MRMai NHalterman MWKim M Long-Term Microgliosis Driven by Acute Systemic Inflammation.; Journal of immunology (Baltimore, Md. : 1950). 2019 Oct 16. Rodriguez LBlanco-Lobo PReilly ECMaehigashi TNogales ASmith ATopham DJDewhurst SKim BMartínez-Sobrido L Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines.; Viruses; Vol 11(10). 2019 Oct 10. Gouma SZost SJParkhouse KBranche ATopham DJCobey SHensley SE Comparison of human H3N2 antibody responses elicited by egg-based, cell-based, and recombinant protein-based influenza vaccines during the 2017-2018 season.; Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2019 Oct 09. Cossarizza AChang HDRadbruch AAcs AAdam DAdam-Klages SAgace WWAghaeepour NAkdis MAllez MAlmeida LNAlvisi GAnderson GAndrä IAnnunziato FAnselmo ABacher PBaldari CTBari SBarnaba VBarros-Martins JBattistini LBauer WBaumgart SBaumgarth NBaumjohann DBaying BBebawy MBecher BBeisker WBenes VBeyaert RBlanco ABoardman DABogdan CBorger JGBorsellino GBoulais PEBradford JABrenner DBrinkman RRBrooks AESBusch DHBüscher MBushnell TPCalzetti FCameron GCammarata ICao XCardell SLCasola SCassatella MACavani ACelada AChatenoud LChattopadhyay PKChow SChristakou EČičin-Šain LClerici MColombo FSCook LCooke ACooper AMCorbett AJCosma ACosmi LCoulie PGCumano ACvetkovic LDang VDDang-Heine CDavey MSDavies DDe Biasi SDel Zotto GDela Cruz GVDelacher MDella Bella SDellabona PDeniz GDessing MDi Santo JPDiefenbach ADieli FDolf ADörner TDress RJDudziak DDustin MDutertre CAEbner FEckle SBGEdinger MEede PEhrhardt GRAEich MEngel PEngelhardt BErdei AEsser CEverts BEvrard MFalk CSFehniger TAFelipo-Benavent MFerry HFeuerer MFilby AFilkor KFillatreau SFollo MFörster IFoster JFoulds GAFrehse BFrenette PSFrischbutter SFritzsche WGalbraith DWGangaev AGarbi NGaudilliere BGazzinelli RTGeginat JGerner WGherardin NAGhoreschi KGibellini LGinhoux FGoda KGodfrey DIGoettlinger CGonzález-Navajas JMGoodyear CSGori AGrogan JLGrummitt DGrützkau AHaftmann CHahn JHammad HHämmerling GHansmann LHansson GHarpur CMHartmann SHauser AHauser AEHaviland DLHedley DHernández DCHerrera GHerrmann MHess CHöfer THoffmann PHogquist KHolland THöllt THolmdahl RHombrink PHouston JPHoyer BFHuang BHuang FPHuber JEHuehn JHundemer MHunter CAHwang WYKIannone AIngelfinger FIvison SMJäck HMJani PKJávega BJonjic SKaiser TKalina TKamradt TKaufmann SHEKeller BKetelaars SLCKhalilnezhad AKhan SKisielow JKlenerman PKnopf JKoay HFKobow KKolls JKKong WTKopf MKorn TKriegsmann KKristyanto HKroneis TKrueger AKühne JKukat CKunkel DKunze-Schumacher HKurosaki TKurts CKvistborg PKwok ILandry JLantz OLanuti PLaRosa FLehuen ALeibundGut-Landmann SLeipold MDLeung LYTLevings MKLino ACLiotta FLitwin VLiu YLjunggren HGLohoff MLombardi GLopez LLópez-Botet MLovett-Racke AELubberts ELuche HLudewig BLugli ELunemann SMaecker HTMaggi LMaguire OMair FMair KHMantovani AManz RAMarshall AJMartínez-Romero AMartrus GMarventano IMaslinski WMatarese GMattioli AVMaueröder CMazzoni AMcCluskey JMcGrath MMcGuire HMMcInnes IBMei HEMelchers FMelzer SMielenz DMiller SDMills KHGMinderman HMjösberg JMoore JMoran BMoretta LMosmann TRMüller SMulthoff GMuñoz LEMünz CNakayama TNasi MNeumann KNg LGNiedobitek ANourshargh SNúñez GO'Connor JEOchel AOja AOrdonez DOrfao AOrlowski-Oliver EOuyang WOxenius APalankar RPanse IPattanapanyasat KPaulsen MPavlinic DPenter LPeterson PPeth CPetriz JPiancone FPickl WFPiconese SPinti MPockley AGPodolska MJPoon ZPracht KPrinz IPucillo CEMQuataert SAQuatrini LQuinn KMRadbruch HRadstake TRDJRahmig SRahn HPRajwa BRavichandran GRaz YRebhahn JARecktenwald DReimer DReis E Sousa CRemmerswaal EBMRichter LRico LGRiddell ARieger AMRobinson JPRomagnani CRubartelli ARuland JSaalmüller ASaeys YSaito TSakaguchi SSala-de-Oyanguren FSamstag YSanderson SSandrock ISantoni ASanz RBSaresella MSautes-Fridman CSawitzki BSchadt LScheffold AScherer HUSchiemann MSchildberg FASchimisky ESchlitzer ASchlosser JSchmid SSchmitt SSchober KSchraivogel DSchuh WSchüler TSchulte RSchulz ARSchulz SRScottá CScott-Algara DSester DPShankey TVSilva-Santos BSimon AKSitnik KMSozzani SSpeiser DESpidlen JStahlberg AStall AMStanley NStark RStehle CSteinmetz TStockinger HTakahama YTakeda KTan LTárnok ATiegs GToldi GTornack JTraggiai ETrebak MTree TIMTrotter JTrowsdale JTsoumakidou MUlrich HUrbanczyk Svan de Veen Wvan den Broek Mvan der Pol EVan Gassen SVan Isterdael Gvan Lier RAWVeldhoen MVento-Asturias SVieira PVoehringer DVolk HDvon Borstel Avon Volkmann KWaisman AWalker RVWallace PKWang SAWang XMWard MDWard-Hartstonge KAWarnatz KWarnes GWarth SWaskow CWatson JVWatzl CWegener LWeisenburger TWiedemann AWienands JWilharm AWilkinson RJWillimsky GWing JBWinkelmann RWinkler THWirz OFWong AWurst PYang JHMYang JYazdanbakhsh MYu LYue AZhang HZhao YZiegler SMZielinski CZimmermann JZychlinsky A Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).; European journal of immunology; Vol 49(10). 2019 Oct. Sangster MYNguyen PQTTopham DJ Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection.; Pathogens (Basel, Switzerland); Vol 8(4). 2019 Sep 28. Sonawane ARTian LChu CYQiu XWang LHolden-Wiltse JGrier AGill SRCaserta MTFalsey ARTopham DJWalsh EEMariani TJWeiss STSilverman EKGlass KLiu YY Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus Infection.; Scientific reports; Vol 9(1). 2019 Sep 25. DiPiazza ATFan SRattan ADeDiego MLChaves FNeumann GKawaoka YSant AJ A Novel Vaccine Strategy to Overcome Poor Immunogenicity of Avian Influenza Vaccines through Mobilization of Memory CD4 T Cells Established by Seasonal Influenza.; Journal of immunology (Baltimore, Md. : 1950); Vol 203(6). 2019 Sep 15. DeDiego MLNogales AMartinez-Sobrido LTopham DJ Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication.; mBio; Vol 10(4). 2019 Aug 27. Richards KAShannon ITreanor JJYang HNayak JLSant AJ Evidence that blunted CD4 T cells responses underlie deficient protective antibody responses to influenza vaccines in repeatedly vaccinated human subjects.; The Journal of infectious diseases. 2019 Aug 26. Gaylo-Moynihan APrizant HPopović MFernandes NRJAnderson CSChiou KKBell HSchrock DCSchumacher JCapece TWalling BLTopham DJMiller JSmrcka AVKim MHughson AFowell DJ Programming of Distinct Chemokine-Dependent and -Independent Search Strategies for Th1 and Th2 Cells Optimizes Function at Inflamed Sites.; Immunity. 2019 Jul 31. Caserta MTYang HBandyopadhyay SQiu XGill SRJava JMcDavid AFalsey ARTopham DJHolden-Wiltse JScheible KPryhuber G Measuring the Severity of Respiratory Illness in the First 2 Years of Life in Preterm and Term Infants.; The Journal of pediatrics. 2019 Jul 31. Rattan ARichards KAKnowlden ZAGSant AJ Protein vaccination directs the CD4+ T cell response towards shared protective epitopes that can be recalled after influenza infection.; Journal of virology. 2019 Jul 24. López-Yglesias AHCamanzo EMartin ATAraujo AMYarovinsky F TLR11-independent inflammasome activation is critical for CD4+ T cell-derived IFN-γ production and host resistance to Toxoplasma gondii.; PLoS pathogens; Vol 15(6). 2019 Jun 13. Walsh EEMariani TJChu CGrier AGill SRQiu XWang LHolden-Wiltse JCorbett AThakar JBenoodt LMcCall MNTopham DJFalsey ARCaserta MT Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study.; JMIR research protocols; Vol 8(6). 2019 Jun 06. Mai NMiller-Rhodes KPrifti VKim MO'Reilly MAHalterman MW Lung-Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia.; Journal of the American Heart Association; Vol 8(9). 2019 May 07. Zhang YBandyopadhyay GTopham DJFalsey ARQiu X Highly efficient hypothesis testing methods for regression-type tests with correlated observations and heterogeneous variance structure.; BMC bioinformatics; Vol 20(1). 2019 Apr 15. Hyun YMChoe YHPark SAKim M LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II.; Experimental & molecular medicine; Vol 51(4). 2019 Apr 09. Schrock DCLeddon SAHughson AMiller JLacy-Hulbert AFowell DJ Pivotal role for αV integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation.; Proceedings of the National Academy of Sciences of the United States of America. 2019 Feb 15. Canales-Benavides AZhuo YAmitrano AMKim MHernandez-Aranda RICarney PSSchnell M Accessible quantitative phase imaging in confocal microscopy with sinusoidal-phase synthetic optical holography.; Applied optics; Vol 58(5). 2019 Feb 10. Tesini BLKanagaiah PWang JHahn MHalliley JLChaves FANguyen PQTNogales ADeDiego MLAnderson CSEllebedy AHStrohmeier SKrammer FYang HBandyopadhyay SAhmed RTreanor JJMartinez-Sobrido LGolding HKhurana SZand MSTopham DJSangster MY Broad hemagglutinin-specific memory B cell expansion by seasonal influenza virus infection reflects early-life imprinting and adaptation to the infecting virus.; Journal of virology. 2019 Feb 06. Arandjelovic SPerry JSALucas CDPenberthy KKKim THZhou MRosen DAChuang TYBettina AMShankman LSCohen AHGaultier AConrads TPKim MElliott MRRavichandran KS A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis.; Nature immunology; Vol 20(2). 2019 Feb. Sant AJ The way forward: Potentiating protective immunity to novel and pandemic influenza through engagement of memory CD4 T cells.; The Journal of infectious diseases. 2019 Jan 31. Henry CZheng NYHuang MCabanov ARojas KTKaur KAndrews SFPalm AEChen YQLi YHoskova KUtset HAVieira MCWrammert JAhmed RHolden-Wiltse JTopham DJTreanor JJErtl HCSchmader KECobey SKrammer FHensley SEGreenberg HHe XSWilson PC Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.; Cell host & microbe. 2019 Jan 24. Varga SMSant AJ Editorial: Orchestration of an Immune Response to Respiratory Pathogens.; Frontiers in immunology; Vol 10. 2019. Nelson SASant AJ Imprinting and Editing of the Human CD4 T Cell Response to Influenza Virus.; Frontiers in immunology; Vol 10. 2019. McRae TDOleksyn DMiller JGao YR Robust blind spectral unmixing for fluorescence microscopy using unsupervised learning.; PloS one; Vol 14(12). 2019. Nogales AMartinez-Sobrido LTopham DJDeDiego ML Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.; Viruses; Vol 10(12). 2018 Dec 12. Safronova AAraujo ACamanzo ETMoon TJElliott MRBeiting DPYarovinsky F Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii.; Nature immunology. 2018 Nov 19. Grier AMcDavid AWang BQiu XJava JBandyopadhyay SYang HHolden-Wiltse JKessler HAGill ALHuyck HFalsey ARTopham DJScheible KMCaserta MTPryhuber GSGill SR Neonatal gut and respiratory microbiota: coordinated development through time and space.; Microbiome; Vol 6(1). 2018 Oct 26. DeDiego MLChiem KTopham DJ Directed selection of amino acid changes in the influenza hemagglutinin and neuraminidase affecting protein antigenicity.; Vaccine. 2018 Sep 14. Kim HRMun YLee KSPark YJPark JSPark JHJeon BNKim CHJun YHyun YMKim MLee SMPark CSIm SHJun CD T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells.; Nature communications; Vol 9(1). 2018 Sep 07. Nogales AMartinez-Sobrido LChiem KTopham DJDeDiego ML FUNCTIONAL EVOLUTION OF THE 2009 PANDEMIC H1N1 INFLUENZA NS1 AND PA IN HUMANS.; Journal of virology. 2018 Jul 18. Zhang HHenry CAnderson CSNogales ADeDiego MLBucukovski JMartinez-Sobrido LWilson PCTopham DJMiller BL Crowd on a Chip: Label-Free Human Monoclonal Antibody Arrays for Serotyping Influenza.; Analytical chemistry. 2018 Jul 09. Branche ARYang HJava JWiltse-Holden JTopham DJPeasley MFrost MRNahm MHFalsey AR Effect of prior vaccination on carriage rates of Streptococcus pneumoniae in older adults: A longitudinal surveillance study.; Vaccine; Vol 36(29). 2018 Jul 05. Sant AJDiPiazza ATNayak JLRattan ARichards KA CD4 T cells in protection from influenza virus: Viral antigen specificity and functional potential.; Immunological reviews; Vol 284(1). 2018 Jul. Topham DJNguyen PSangster MY Pandemic influenza vaccines: what they have taught us about B cell immunology.; Current opinion in immunology; Vol 53. 2018 Jun 26. Walsh EEWang LFalsey ARQiu XCorbett AHolden-Wiltse JMariani TJTopham DJCaserta MT Virus-Specific Antibody, Viral Load, and Disease Severity in Respiratory Syncytial Virus Infection.; The Journal of infectious diseases; Vol 218(2). 2018 Jun 20. Roumanes DFalsey ARQuataert SSecor-Socha SLee FEYang HBandyopadhyay SHolden-Wiltse JTopham DJWalsh EE T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection.; The Journal of infectious diseases. 2018 Jun 16. Richards KATreanor JJNayak JLSant AJ Overarching Immunodominance Patterns and Substantial Diversity in Specificity and Functionality in the Circulating Human Influenza A and B CD4 T Cell Repertoire.; The Journal of infectious diseases. 2018 May 12. DiPiazza ALaniewski NRattan ATopham DJMiller JSant AJ CD4 T cell epitope specificity and cytokine potential are preserved as cells transition from the lung vasculature to lung tissue following influenza infection.; Journal of virology. 2018 Apr 18. Chen YQWohlbold TJZheng NYHuang MHuang YNeu KELee JWan HRojas KTKirkpatrick EHenry CPalm AEStamper CTLan LYTopham DJTreanor JWrammert JAhmed REichelberger MCGeorgiou GKrammer FWilson PC Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies.; Cell; Vol 173(2). 2018 Apr 05. Berry BJTrewin AJAmitrano AMKim MWojtovich AP Use the protonmotive force: Mitochondrial uncoupling and reactive oxygen species.; Journal of molecular biology. 2018 Apr 04. Sant AJRichards KANayak J Distinct and complementary roles of CD4 T cells in protective immunity to influenza virus.; Current opinion in immunology; Vol 53. 2018 Apr 02. Anderson CSOrtega SChaves FAClark AMYang HTopham DJDeDiego ML Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain.; Scientific reports; Vol 8(1). 2018 Mar 06. Scheible KMEmo JLaniewski NBaran AMPeterson DRHolden-Wiltse JBandyopadhyay SStraw AGHuyck HAshton JMTripi KSArul KWerner EScalise TMaffett DCaserta MRyan RMReynolds AMRen CLTopham DJMariani TJPryhuber GS T cell developmental arrest in former premature infants increases risk of respiratory morbidity later in infancy.; JCI insight; Vol 3(4). 2018 Feb 22. Burger EAraujo ALópez-Yglesias ARajala MWGeng LLevine BHooper LVBurstein EYarovinsky F Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation.; Cell host & microbe; Vol 23(2). 2018 Feb 14. Anderson CSMcCall PRStern HAYang HTopham DJ Antigenic cartography of H1N1 influenza viruses using sequence-based antigenic distance calculation.; BMC bioinformatics; Vol 19(1). 2018 Feb 12. Anderson CSOrtega SChaves FAClark AMYang HTopham DJDeDiego ML Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain.; Scientific reports; Vol 8(1). 2018 Jan 05. López-Yglesias AHBurger EAraujo AMartin ATYarovinsky F T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection.; Mucosal immunology. 2018 Jan 03. Burger EAraujo ALópez-Yglesias ARajala MWGeng LLevine BHooper LVBurstein EYarovinsky F Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation; Cell Host & Microbe. 2018 Jan 01. Walling BLKim M LFA-1 in T Cell Migration and Differentiation.; Frontiers in immunology; Vol 9. 2018. Topham DJReilly EC Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function.; Frontiers in immunology; Vol 9. 2018. Wang JHilchey SPDeDiego MPerry SHyrien ONogales AGarigen JAmanat FHuertas NKrammer FMartinez-Sobrido LTopham DJTreanor JJSangster MYZand MS Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.; PloS one; Vol 13(4). 2018. Richards KADiPiazza ATRattan AKnowlden ZAGYang HSant AJ Diverse Epitope Specificity, Immunodominance Hierarchy, and Functional Avidity of Effector CD4 T Cells Established During Priming Is Maintained in Lung After Influenza A Virus Infection.; Frontiers in immunology; Vol 9. 2018. DiPiazza ATRichards KALiu WCAlbrecht RASant AJ Analyses of Cellular Immune Responses in Ferrets Following Influenza Virus Infection.; Methods in molecular biology (Clifton, N.J.); Vol 1836. 2018. Ford JHughson ALim KBardina SVLu WCharo IFLim JKFowell DJ CCL7 Is a Negative Regulator of Cutaneous Inflammation Following Leishmania major Infection.; Frontiers in immunology; Vol 9. 2018. Anderson CSOrtega SChaves FAClark AMYang HTopham DJDeDiego ML Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain.; Scientific reports; Vol 7(1). 2017 Nov 06. Cossarizza AChang HDRadbruch AAndrä IAnnunziato FBacher PBarnaba VBattistini LBauer WMBaumgart SBecher BBeisker WBerek CBlanco ABorsellino GBoulais PEBrinkman RRBüscher MBusch DHBushnell TPCao XCavani AChattopadhyay PKCheng QChow SClerici MCooke ACosma ACosmi LCumano ADang VDDavies DDe Biasi SDel Zotto GDella Bella SDellabona PDeniz GDessing MDiefenbach ADi Santo JDieli FDolf ADonnenberg VSDörner TEhrhardt GRAEndl EEngel PEngelhardt BEsser CEverts BFalk CSFehniger TAFilby AFillatreau SFollo MFörster IFoster JFoulds GAFrenette PSGalbraith DGarbi NGarcía-Godoy MDGhoreschi KGibellini LGoettlinger CGoodyear CSGori AGrogan JGross MGrützkau AGrummitt DHahn JHammer QHauser AEHaviland DLHedley DHerrera GHerrmann MHiepe FHolland THombrink PHouston JPHoyer BFHuang BHunter CAIannone AJäck HMJávega BJonjic SJuelke KJung SKaiser TKalina TKeller BKhan SKienhöfer DKroneis TKunkel DKurts CKvistborg PLannigan JLantz OLarbi ALeibundGut-Landmann SLeipold MDLevings MKLitwin VLiu YLohoff MLombardi GLopez LLovett-Racke ALubberts ELudewig BLugli EMaecker HTMartrus GMatarese GMaueröder CMcGrath MMcInnes IMei HEMelchers FMelzer SMielenz DMills KMjösberg JMoore JMoran BMoretta AMoretta LMosmann TRMüller SMüller WMünz CMulthoff GMunoz LEMurphy KMNakayama TNasi MNeudörfl CNolan JNourshargh SO'Connor JEOuyang WOxenius APalankar RPanse IPeterson PPeth CPetriz JPhilips DPickl WPiconese SPinti MPockley AGPodolska MJPucillo CQuataert SARadstake TRDJRajwa BRebhahn JARecktenwald DRemmerswaal EBMRezvani KRico LGRobinson JPRomagnani CRubartelli ARuland JSakaguchi SSala-de-Oyanguren FSamstag YSanderson SSawitzki BScheffold ASchiemann MSchildberg FSchimisky ESchmid SASchmitt SSchober KSchüler TSchulz ARSchumacher TScotta CShankey TVShemer ASimon AKSpidlen JStall AMStark RStehle CStein MSteinmetz TStockinger HTakahama YTarnok ATian ZToldi GTornack JTraggiai ETrotter JUlrich Hvan der Braber Mvan Lier RAWVeldhoen MVento-Asturias SVieira PVoehringer DVolk HDvon Volkmann KWaisman AWalker RWard MDWarnatz KWarth SWatson JVWatzl CWegener LWiedemann AWienands JWillimsky GWing JWurst PYu LYue AZhang QZhao YZiegler SZimmermann J Guidelines for the use of flow cytometry and cell sorting in immunological studies.; European journal of immunology; Vol 47(10). 2017 Oct. Capece TWalling BLLim KKim KDBae SChung HLTopham DJKim M A novel intracellular pool of LFA-1 is critical for asymmetric CD8(+) T cell activation and differentiation.; The Journal of cell biology. 2017 Sep 27. DiPiazza ANogales APoulton NWilson PCMartínez-Sobrido LSant AJ Pandemic 2009 H1N1 Influenza Venus reporter virus reveals broad diversity of MHC class II-positive antigen-bearing cells following infection in vivo.; Scientific reports; Vol 7(1). 2017 Sep 07. Sarangi PPLee HWLerman YVTrzeciak AHarrower EJRezaie ARKim M Activated Protein C Attenuates Severe Inflammation by Targeting VLA-3(high) Neutrophil Subpopulation in Mice.; Journal of immunology (Baltimore, Md. : 1950). 2017 Sep 06. Nogales AChauché CDeDiego MLTopham DJParrish CRMurcia PRMartínez-Sobrido L Amino acid substitution K186E in the canine influenza virus H3N8 NS1 protein restores its ability to inhibit host gene expression.; Journal of virology. 2017 Aug 23. Mariani TJQiu XChu CYWang LThakar JHolden-Wiltse JCorbett ATopham DJFalsey ARCaserta MTWalsh EE Dynamic changes in the CD4 T cell transcriptome are associated with disease severity during primary RSV infection in young infants.; The Journal of infectious diseases. 2017 Aug 17. Bhattacharya SRosenberg AFPeterson DRGrzesik KBaran AMAshton JMGill SRCorbett AMHolden-Wiltse JTopham DJWalsh EEMariani TJFalsey AR Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.; Scientific reports; Vol 7(1). 2017 Jul 26. Clark AMNogales AMartinez-Sobrido LTopham DJDeDiego ML Functional evolution of influenza NS1 protein in currently circulating human 2009 pandemic H1N1 viruses.; Journal of virology. 2017 Jun 21. Nogales ARodriguez LDeDiego MLTopham DJMartínez-Sobrido L Interplay of PA-X and NS1 proteins in replication and pathogenesis of a temperature-sensitive 2009 pandemic H1N1 influenza A virus.; Journal of virology. 2017 Jun 21. Yang HHolden-Wiltse JTopham DJTreanor J Maximum Likelihood Estimation of Titer via a Power Family of Four-Parameter Logistic Model.; Journal of biopharmaceutical statistics. 2017 May 25. Kim KDBae SCapece TNedelkovska Hde Rubio RGSmrcka AVJun CDJung WPark BKim TIKim M Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment.; Nature communications; Vol 8. 2017 May 15. Basha SKaur RMosmann TRPichichero ME Reduced T-Helper 17 Responses to Streptococcus pneumoniae in Infection-Prone Children Can Be Rescued by Addition of Innate Cytokines.; The Journal of infectious diseases; Vol 215(8). 2017 Apr 15. Rodriguez LNogales AReilly ECTopham DJMurcia PRParrish CRMartinez Sobrido L A live-attenuated influenza vaccine for H3N2 canine influenza virus.; Virology; Vol 504. 2017 Apr. Caserta MTQiu XTesini BWang LMurphy ACorbett ATopham DJFalsey ARHolden-Wiltse JWalsh EE Development of a Global Respiratory Severity Score for Respiratory Syncytial Virus Infection in Infants.; The Journal of infectious diseases; Vol 215(5). 2017 Mar 01. DiPiazza ARichards KPoulton NSant AJ Avian and Human Seasonal Influenza Hemagglutinin Proteins Elicit CD4 T Cell Responses That Are Comparable in Epitope Abundance and Diversity.; Clinical and vaccine immunology : CVI; Vol 24(3). 2017 Mar. Ramani SNeill FHFerreira JTreanor JJFrey SETopham DJGoodwin RRBorkowski ABaehner FMendelman PMEstes MKAtmar RL B-Cell Responses to Intramuscular Administration of a Bivalent Virus-like Particle Human Norovirus Vaccine.; Clinical and vaccine immunology : CVI. 2017 Mar 01. Nogales AMartinez-Sobrido LTopham DJDeDiego ML NS1 Protein Amino Acid Changes D189N and V194I Affect Interferon Responses, Thermosensitivity, and Virulence of Circulating H3N2 Human Influenza A Viruses.; Journal of virology; Vol 91(5). 2017 Mar 01. Zhang YTopham DJThakar JQiu X FUNNEL-GSEA: FUNctioNal ELastic-net regression in time-course gene set enrichment analysis.; Bioinformatics (Oxford, England). 2017 Feb 21. Nogales ARodriguez LChauché CHuang KReilly ECTopham DJMurcia PRParrish CRMartínez-Sobrido L Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine.; Journal of virology; Vol 91(4). 2017 Feb 15. Clark AMDeDiego MLAnderson CSWang JYang HNogales AMartinez-Sobrido LZand MSSangster MYTopham DJ Antigenicity of the 2015-2016 seasonal H1N1 human influenza virus HA and NA proteins.; PloS one; Vol 12(11). 2017. Pedersen NWChandran PAQian YRebhahn JPetersen NVHoff MDWhite SLee AJStanton RHalgreen CJakobsen KMosmann TGouttefangeas CChan CScheuermann RHHadrup SR Automated Analysis of Flow Cytometry Data to Reduce Inter-Lab Variation in the Detection of Major Histocompatibility Complex Multimer-Binding T Cells.; Frontiers in immunology; Vol 8. 2017. Johnson CMO'Brien XMByrd ASParisi VELoosely AJLi WWitt HFaridi HMLefort CTGupta VKim MReichner JS Integrin Cross-Talk Regulates the Human Neutrophil Response to Fungal β-Glucan in the Context of the Extracellular Matrix: A Prominent Role for VLA3 in the Antifungal Response.; Journal of immunology (Baltimore, Md. : 1950); Vol 198(1). 2017 Jan 01. Connolly KABelt BAFigueroa NMMurthy APatel AKim MLord EMLinehan DCGerber SA Increasing the efficacy of radiotherapy by modulating the CCR2/CCR5 chemokine axes.; Oncotarget. 2016 Nov 11. Meli APFontés GAvery DTLeddon SATam MElliot MBallesteros-Tato AMiller JStevenson MMFowell DJTangye SGKing IL The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.; Immunity; Vol 45(4). 2016 Oct 18. Chiu YHSchwarz ELi DXu YSheu TRLi JBentley KLFeng CWang BWang JCAlbertorio-Saez LWood RKim MWang WRitchlin CT Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Regulates Osteoclast Differentiation via the Ca2+ /NFATc1 Axis.; Journal of cellular physiology. 2016 Oct 10. DiPiazza ARichards KBatarse FLockard LZeng HGarcía-Sastre AAlbrecht RASant AJ Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection.; Journal of virology; Vol 90(17). 2016 Sep 01. Fiorentino DFZlotnik AMosmann TRHoward MO'Garra A Pillars Article: IL-10 Inhibits Cytokine Production by Activated Macrophages. J. Immunol. 1991. 147: 3815-3822.; Journal of immunology (Baltimore, Md. : 1950); Vol 197(5). 2016 Sep 01. Fiorentino DFZlotnik AVieira PMosmann TRHoward MMoore KWO'Garra A Pillars Article: IL-10 Acts on the Antigen-presenting Cell to Inhibit Cytokine Production by Thl Cells. J. Immunol. 1991. 146: 3444-3451.; Journal of immunology (Baltimore, Md. : 1950); Vol 197(5). 2016 Sep 01. Lambert Emo KHyun YMReilly EBarilla CGerber SFowell DKim MTopham DJ Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen.; PLoS pathogens; Vol 12(9). 2016 Sep. DeDiego MLNogales ALambert-Emo KMartinez-Sobrido LTopham DJ An NS1 protein mutation (I64T) affects interferon responses and virulence of circulating H3N2 human influenza A viruses.; Journal of virology. 2016 Aug 17. Billroth-MacLurg ACFord JRosenberg AMiller JFowell DJ Regulatory T Cell Numbers in Inflamed Skin Are Controlled by Local Inflammatory Cues That Upregulate CD25 and Facilitate Antigen-Driven Local Proliferation.; Journal of immunology (Baltimore, Md. : 1950). 2016 Aug 10. Capece TKim M The Role of Lymphatic Niches in T Cell Differentiation.; Molecules and cells. 2016 Jun 16. Pichichero MECasey JRAlmudevar ABasha SSurendran NKaur RMorris MLivingstone AMMosmann TR Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants.; The Journal of infectious diseases; Vol 213(12). 2016 Jun 15. Henry Dunand CJLeon PEHuang MChoi AChromikova VHo IYTan GSCruz JHirsh AZheng NYMullarkey CEEnnis FATerajima MTreanor JJTopham DJSubbarao KPalese PKrammer FWilson PC Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection.; Cell host & microbe; Vol 19(6). 2016 Jun 8.