Events

Katalin Gothard, MD, PhD - Professor, Departments of Physiology and Neuroscience, University of Arizona Health Sciences Center

 Mar 30, 2023 @ 4:00 p.m.

 Medical Center | Ryan Case Method (1-9576)

Host: Lizabeth Romanski

Shinho Cho, PhD - Research Associate, University of Minnesota Medical School
Center for Magnetic Resonance Research and Departments of Radiology

Dr. Cho’s research aims to delineate the dynamic interaction and casual relationship between macro-, meso-, and microscopic-scale functional brain activity that underlies cognition, behavior, and clinical symptoms. He will present the functional relationship between the activity of subcortical brain regions and large-scale brain networks. Simultaneous deep brain stimulation and functional MRI (fMRI) in human and animal brains reveal that neuromodulation on deep brain structure (e.g., nucleus accumbens) altered not only the whole-brain network connectivity but influenced patients' cognition (e.g., mood). The following topic will illuminate the mesoscopic cortical layer and columnar organization that subserves visual orientation encoding in cats' primary visual cortex. The 9.4 Tesla fMRI and multiphoton optical imaging reveal the cortical layer-dependent orientation tuning property of hemodynamics response, reflected by vessel dilation and constriction. Dr. Cho will discuss the multimodal imaging (e.g., PET-MR) that bridges the gap of the dynamics between neurotransmitters (e.g., dopamine) and macroscopic brain networks; how the deficiency of neurotransmitters would impact brain and behaviors systematically. Overall, these findings and the integrated approach of different imaging modalities, behavioral assessment, and neuromodulation can characterize causal and correlational relationships in the hierarchical brain, providing a unique opportunity to understand the biological basis of cognition/behavior and neurologic/psychiatric disorders.

Flyer

 Feb 28, 2023 @ 4:00 p.m.

 Medical Center | Upper Auditorium (3-7619)

Host: University of Rochester School of Medicine and Dentistry, Department of Neuroscience, and the Del Monte Institute for Neuroscience

Abigail Alpers; Jeeyun Kim - PhD Candidate, Neuroscience Graduate Program

Titles: Effects of deep brain stimulation on neurophysiology and cognition in Parkinson's Disease - Kim
The ferret natural vision project - Alpers

Faculty Evaluators: Ed Freedman & Marc Schieber

 Feb 27, 2023 @ 4:00 p.m.

 Medical Center | K-307

Julia Granato - PhD Candidate, Neuroscience Graduate Program

Title:  The role of Sez6L2 in regulating complement-mediated synaptic pruning during neurodevelopment

Faculty Evaluators: Ian Fiebelkorn & Greg DeAngelis

 Feb 13, 2023 @ 4:00 p.m.

 Medical Center | K-307