Faculty

Signaling transduction mechanisms in the vascular system

Epidemiology and pathogenesis of respiratory viruses (influenza, RSV, COVID). Vaccine development. Immunology.


Environmental epidemiology of the effect of air polution on respiratory health



Understanding the pathogenesis of Acute Lung Injury (ALI), a life threatening pulmonary inflammatory condition

Defining molecular pathways by which allergens and particulates activate epithelia and dendritic cells in the lung immune system

Development of the infant microbiome and immune system, and how that relates to development of allergic diseases

Cancer immunotherapy/Host immune response to influenza infection/ Inflammation biology of sepsis

Improve and provide access to care for patients with pulmonary vascular disease

Delineating mechanisms by which environmental exposures during different life stages alter immune function



Genetic and environmental susceptibility to developmental lung injury

In vitro models of human lung and vascular barriers during inflammation

Airway epithelial stem cells in chemical inhalation exposures

Platelets in vascular injury and inflammation

Defining how an aberrant oxygen environment and oxygen-induced DNA damage signaling alter distal lung development, the host response to respiratory viral infections, and promotes cardiovascular disease later in life

Team approaches to patient-centered, clinical and translational investigation in sepsis and critical illness

Chronic lung disease of prematurity and lung development

The mechanisms of lung vascular endothelial cell dysfunction in acute lung injury

Redox signaling mechanism of Proinflammatory gene expression in pathogenesis of chronic inflammatory lung diseases caused by environmental toxicants

Cardiovascular, respiratory, and perinatal/reproductive health effects of exposure to environmental agents, including ambient air pollution

Early detection of lung cancer, toxicities caused by therapies in lung cancer, and the prevalence of lung cancer in women

Innate cell antiviral responses, allergic inflammation, mucosal/airway immunity, vaccine responses

Specificity and role of CD4 T cells in response to vaccination and infection

Neonatal immunology; T cell function in preterm infants

Cellular and molecular mechanisms of heart development, disease, and regeneration; Transcriptional regulation of fibroblast plasticity and cardiac fibrosis

Using statistics in environmental health, measurement error, multiple outcomes, Bayesian inference

Immune responses to respiratory viruses and experimental vaccines

Thrombosis and platelet activation in vascular pathology of pulmonary hypertension; clinical trial design in pulmonary hypertension
