Recent Publications

• 1. Anders MW
  Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria.; Mitochondrion; Vol 13(5). 2013 Sep.
• 1. Anders MW
  Putting bioactivation reactions to work: Targeting antioxidants to mitochondria.; Chemico-biological interactions; Vol 192(1-2). 2011 Jun 30.
• 1. Board PG
  2. Anders MW
  Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice.; Drug metabolism reviews; Vol 43(2). 2011 May.
• 1. Roser KS
  2. Brookes PS
  3. Wojtovich AP
  4. Olson LP
  5. Shojaie J
  6. Parton RL
  7. Anders MW
  Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria.; Bioorganic & medicinal chemistry; Vol 18(4). 2010 Feb 15.
• 1. Xu L
  2. Krenitsky DM
  3. Seacat AM
  4. Butenhoff JL
  5. Tephly TR
  6. Anders MW
  N-glucuronidation of perfluorooctanesulfonamide by human, rat, dog, and monkey liver microsomes and by expressed rat and human UDP-glucuronosyltransferases.; Drug metabolism and disposition: the biological fate of chemicals; Vol 34(8). 2006 Aug.
• 1. Starr TB
  2. Matanoski G
  3. Anders MW
  4. Andersen ME
  Workshop overview: reassessment of the cancer risk of dichloromethane in humans.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 91(1). 2006 May.
• 1. Fang YY
  2. Kashkarov U
  3. Anders MW
  4. Board PG
  Polymorphisms in the human glutathione transferase zeta promoter.; Pharmacogenetics and genomics; Vol 16(5). 2006 May.
• 1. Blackburn AC
  2. Matthaei KI
  3. Lim C
  4. Taylor MC
  5. Cappello JY
  6. Hayes JD
  7. Anders MW
  8. Board PG
  Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways.; Molecular pharmacology; Vol 69(2). 2006 Feb.
• 1. Sheu SS
  2. Nauduri D
  3. Anders MW
  Targeting antioxidants to mitochondria: a new therapeutic direction.; Biochimica et biophysica acta; Vol 1762(2). 2006 Feb.
• 1. Anders MW
  2. Robotham JL
  3. Sheu SS
  Mitochondria: new drug targets for oxidative stress-induced diseases.; Expert opinion on drug metabolism & toxicology; Vol 2(1). 2006 Feb.
• 1. Board PG
  2. Anders MW
  Human glutathione transferase zeta.; Methods in enzymology; Vol 401. 2005.
• 1. Anders MW
  Formation and toxicity of anesthetic degradation products.; Annual review of pharmacology and toxicology; Vol 45. 2005.
• 1. Anders MW
  Glutathione-dependent bioactivation of haloalkanes and haloalkenes.; Drug metabolism reviews; Vol 36(3-4). 2004 Oct.
• 1. Brookes PS
  2. Yoon Y
  3. Robotham JL
  4. Anders MW
  5. Sheu SS
  Calcium, ATP, and ROS: a mitochondrial love-hate triangle.; American journal of physiology. Cell physiology; Vol 287(4). 2004 Oct.
• 1. Lim CE
  2. Matthaei KI
  3. Blackburn AC
  4. Davis RP
  5. Dahlstrom JE
  6. Koina ME
  7. Anders MW
  8. Board PG
  Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases.; The American journal of pathology; Vol 165(2). 2004 Aug.
• 1. Xu L
  2. Krenitsky DM
  3. Seacat AM
  4. Butenhoff JL
  5. Anders MW
  Biotransformation of N-ethyl-N-(2-hydroxyethyl)perfluorooctanesulfonamide by rat liver microsomes, cytosol, and slices and by expressed rat and human cytochromes P450.; Chemical research in toxicology; Vol 17(6). 2004 Jun.
• 1. Anderson WB
  2. Board PG
  3. Anders MW
  Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles.; Chemical research in toxicology; Vol 17(5). 2004 May.
• 1. Lantum HB
  2. Iyer RA
  3. Anders MW
  Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities.; Biochemical pharmacology; Vol 67(7). 2004 Apr 1.
• 1. Board PG
  2. Taylor MC
  3. Coggan M
  4. Parker MW
  5. Lantum HB
  6. Anders MW
  Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique.; The Biochemical journal; Vol 374(Pt 3). 2003 Sep 15.
• 1. Lantum HB
  2. Cornejo J
  3. Pierce RH
  4. Anders MW
  Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 74(1). 2003 Jul.
• 1. Jolivette LJ
  2. Anders MW
  Computational and experimental studies on the distribution of addition and substitution products of the microsomal glutathione transferase 1-catalyzed conjugation of glutathione with fluoroalkenes.; Chemical research in toxicology; Vol 16(2). 2003 Feb.
• 1. Lantum HB
  2. Baggs RB
  3. Krenitsky DM
  4. Anders MW
  Nephrotoxicity of chlorofluoroacetic acid in rats.; Toxicological sciences : an official journal of the Society of Toxicology; Vol 70(2). 2002 Dec.
• 1. Anderson WB
  2. Liebler DC
  3. Board PG
  4. Anders MW
  Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta.; Chemical research in toxicology; Vol 15(11). 2002 Nov.
• 1. Enomoto A
  2. Wempe MF
  3. Tsuchida H
  4. Shin HJ
  5. Cha SH
  6. Anzai N
  7. Goto A
  8. Sakamoto A
  9. Niwa T
  10. Kanai Y
  11. Anders MW
  12. Endou H
  Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.; The Journal of biological chemistry; Vol 277(39). 2002 Sep 27.
• 1. Cooper AJ
  2. Bruschi SA
  3. Anders MW
  Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism.; Biochemical pharmacology; Vol 64(4). 2002 Aug 15.
• 1. Jolivette LJ
  2. Anders MW
  Structure-activity relationship for the biotransformation of haloalkenes by rat liver microsomal glutathione transferase 1.; Chemical research in toxicology; Vol 15(8). 2002 Aug.
• 1. Lantum HB
  2. Board PG
  3. Anders MW
  Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1).; Chemical research in toxicology; Vol 15(7). 2002 Jul.
• 1. Lantum HB
  2. Baggs RB
  3. Krenitsky DM
  4. Board PG
  5. Anders MW
  Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues.; Drug metabolism and disposition: the biological fate of chemicals; Vol 30(6). 2002 Jun.
• 1. Tong Z
  2. Anders MW
  Reactive intermediate formation from the 2-(Fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A)-derived cysteine S-conjugate S-[2-(Fluoromethoxy)-1,1,3,3,3-pentafluoropropyl]-L-cysteine in pyridoxal model systems.; Chemical research in toxicology; Vol 15(5). 2002 May.
• 1. Lantum HB
  2. Liebler DC
  3. Board PG
  4. Anders MW
  Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.; Chemical research in toxicology; Vol 15(5). 2002 May.
• 1. Bayer T
  2. Amberg A
  3. Bertermann R
  4. Rusch GM
  5. Anders MW
  6. Dekant W
  Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa).; Chemical research in toxicology; Vol 15(5). 2002 May.
• 1. Uchino H
  2. Kanai Y
  3. Kim DK
  4. Wempe MF
  5. Chairoungdua A
  6. Morimoto E
  7. Anders MW
  8. Endou H
  Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition.; Molecular pharmacology; Vol 61(4). 2002 Apr.
• 1. Pombrio JM
  2. Giangreco A
  3. Li L
  4. Wempe MF
  5. Anders MW
  6. Sweet DH
  7. Pritchard JB
  8. Ballatori N
  Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.; Molecular pharmacology; Vol 60(5). 2001 Nov.
• 1. Blackburn AC
  2. Coggan M
  3. Tzeng HF
  4. Lantum H
  5. Polekhina G
  6. Parker MW
  7. Anders MW
  8. Board PG
  GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase.; Pharmacogenetics; Vol 11(8). 2001 Nov.
• 1. DeCory HH
  2. Piech-Dumas KM
  3. Sheu SS
  4. Federoff HJ
  5. Anders MW
  Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons.; Drug metabolism and disposition: the biological fate of chemicals; Vol 29(10). 2001 Oct.
• 1. Board PG
  2. Chelvanayagam G
  3. Jermiin LS
  4. Tetlow N
  5. Tzeng HF
  6. Anders MW
  7. Blackburn AC
  Identification of novel glutathione transferases and polymorphic variants by expressed sequence tag database analysis.; Drug metabolism and disposition: the biological fate of chemicals; Vol 29(4 Pt 2). 2001 Apr.
• 1. Chen Y
  2. Cai J
  3. Anders MW
  4. Stevens JL
  5. Jones DP
  Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.; Toxicology and applied pharmacology; Vol 170(3). 2001 Feb 1.
• 1. Anders MW
  Formation and fate of reactive intermediates of haloalkanes, haloalkenes, and alpha-haloacids.; Advances in experimental medicine and biology; Vol 500. 2001.
• 1. Lantum HB
  2. Board PG
  3. Anders MW
  Inactivation of polymorphic variants of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.; Advances in experimental medicine and biology; Vol 500. 2001.
• 1. Luu NC
  2. Iyer RA
  3. Anders MW
  4. Ridge DP
  Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions.; Chemical research in toxicology; Vol 13(7). 2000 Jul.
• 1. Uttamsingh V
  2. Baggs RB
  3. Krenitsky DM
  4. Anders MW
  Immunohistochemical localization of the acylases that catalyze the deacetylation of N-acetyl-L-cysteine and haloalkene-derived mercapturates.; Drug metabolism and disposition: the biological fate of chemicals; Vol 28(6). 2000 Jun.
• 1. Tzeng HF
  2. Blackburn AC
  3. Board PG
  4. Anders MW
  Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate.; Chemical research in toxicology; Vol 13(4). 2000 Apr.
• 1. Kraus T
  2. Uttamsingh V
  3. Anders MW
  4. Wolf S
  Porcine kidney microsomal cysteine S-conjugate N-acetyltransferase-catalyzed N-acetylation of haloalkene-derived cysteine S-conjugates.; Drug metabolism and disposition: the biological fate of chemicals; Vol 28(4). 2000 Apr.
• 1. Morrow PE
  2. Witschi H
  3. Vore M
  4. Hakkinen PE
  5. MacGregor J
  6. MacGregor J
  7. Anders MW
  8. Willhite C
  Profiles in toxicology. Harold Carpenter Hodge (1904-1990).; Toxicological sciences : an official journal of the Society of Toxicology; Vol 53(2). 2000 Feb.
• 1. Blackburn AC
  2. Tzeng HF
  3. Anders MW
  4. Board PG
  Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis.; Pharmacogenetics; Vol 10(1). 2000 Feb.
• 1. Anderson WB
  2. Board PG
  3. Gargano B
  4. Anders MW
  Inactivation of glutathione transferase zeta by dichloroacetic acid and other fluorine-lacking alpha-haloalkanoic acids.; Chemical research in toxicology; Vol 12(12). 1999 Dec.
• 1. Uttamsingh V
  2. Anders MW
  Acylase-catalyzed deacetylation of haloalkene-derived mercapturates.; Chemical research in toxicology; Vol 12(10). 1999 Oct.
• 1. Wempe MF
  2. Anderson WB
  3. Tzeng HF
  4. Board PG
  5. Anders MW
  Glutathione transferase zeta-catalyzed biotransformation of deuterated dihaloacetic acids.; Biochemical and biophysical research communications; Vol 261(3). 1999 Aug 11.
• 1. Tu Z
  2. Anders MW
  Identification of an important cysteine residue in human glutamate-cysteine ligase catalytic subunit by site-directed mutagenesis.; The Biochemical journal; Vol 336 ( Pt 3). 1998 Dec 15.
• 1. Tong Z
  2. Board PG
  3. Anders MW
  Glutathione transferase zeta-catalyzed biotransformation of dichloroacetic acid and other alpha-haloacids.; Chemical research in toxicology; Vol 11(11). 1998 Nov.