Publications
Publications
- The 27th Scientific Conference of the Society on NeuroImmune Pharmacology: New Delhi, India, March 15-18, 2023.; NeuroImmune pharmacology and therapeutics; Vol 2(2), pp. 187-244. 2023 Apr 10.
- The Neuroimmune Pharmacology of SARS-CoV-2.; Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021 Dec 22.
- The COVID-19 Pandemic: Reflections of Science, Person, and Challenge in Academic Research Settings.; Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021 Nov 26.
- Mice with high FGF21 serum levels had a reduced preference for morphine and an attenuated development of acute antinociceptive tolerance and physical dependence.; Neuropharmacology; Vol 202. 2021 Oct 26.
- Society on NeuroImmune Pharmacology COVID-19 Virtual Workshop.; Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2021 Jun 28.
- The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia.; International journal of molecular sciences; Vol 22(1). 2020 Dec 22.
- Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Tranfer.; Molecular pharmacology; Vol 98(4). 2020 Oct.
- Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration.; Psychopharmacology. 2020 Jan 07.
- Author Correction: Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.; Nature neuroscience. 2019 Nov 27.
- Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.; Nature neuroscience. 2019 Oct 21.
- In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being Developed as an Adjunctive Treatment for Major Depressive Disorder.; The Journal of pharmacology and experimental therapeutics. 2018 Aug 14.
- Antidepressant-like effects of 3-carboxamido seco-nalmefene (3CS-nalmefene), a novel opioid receptor modulator, in a rat IFN-α-induced depression model.; Brain, behavior, and immunity. 2017 Aug 24.
- Structural Requirements for CNS Active Opioid Glycopeptides.; Journal of medicinal chemistry; Vol 58(15). 2015 Aug 13.
- Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to β-endorphin?; Journal of medicinal chemistry; Vol 57(6). 2014 Mar 27.
- Preliminary pharmacological evaluation of enantiomeric morphinans.; ACS chemical neuroscience; Vol 5(2). 2014 Feb 19.
- Mixed κ/μ partial opioid agonists as potential treatments for cocaine dependence.; Advances in pharmacology (San Diego, Calif.); Vol 69. 2014.
- Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors.; Journal of medicinal chemistry; Vol 56(21). 2013 Nov 14.
- Inhibition of Gβγ-subunit signaling potentiates morphine-induced antinociception but not respiratory depression, constipation, locomotion, and reward.; Behavioural pharmacology; Vol 24(2). 2013 Apr.
- Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors.; Bioorganic & medicinal chemistry letters; Vol 23(7). 2013 Apr 1.
- Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 8. High affinity ligands for opioid receptors in the picomolar Ki range: oxygenated N-(2-[1,1'-biphenyl]-4-ylethyl) analogues of 8-CAC.; Bioorganic & medicinal chemistry letters; Vol 22(24). 2012 Dec 15.
- Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.; Journal of medicinal chemistry; Vol 55(8). 2012 Apr 26.
- Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins.; Future medicinal chemistry; Vol 4(2). 2012 Feb.
- Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats.; Pharmacology, biochemistry, and behavior; Vol 100(3). 2012 Jan.
- Phosphorylation of enkephalins: NMR and CD studies in aqueous and membrane-mimicking environments.; Chemical biology & drug design; Vol 78(5). 2011 Nov.
- Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors.; Bioorganic & medicinal chemistry; Vol 19(9). 2011 May 1.
- Brain P450 epoxygenase activity is required for the antinociceptive effects of improgan, a nonopioid analgesic.; Pain; Vol 152(4). 2011 Apr.
- Aminothiazolomorphinans with mixed κ and μ opioid activity.; Journal of medicinal chemistry; Vol 54(6). 2011 Mar 24.
- In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice.; The Journal of pharmacology and experimental therapeutics; Vol 336(3). 2011 Mar.
- Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic.; European journal of medicinal chemistry; Vol 46(2). 2011 Feb.
- Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling.; Nature neuroscience; Vol 13(3). 2010 Mar.
- Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors.; Bioorganic & medicinal chemistry letters; Vol 20(5). 2010 Mar 1.
- Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid Pharmacophore.; ACS chemical neuroscience; Vol 1(2). 2010 Feb 17.
- Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors.; Journal of medicinal chemistry; Vol 53(1). 2010 Jan 14.
- Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands.; Journal of medicinal chemistry; Vol 52(23). 2009 Dec 10.
- Syntheses of novel high affinity ligands for opioid receptors.; Bioorganic & medicinal chemistry letters; Vol 19(8). 2009 Apr 15.
- Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 7: syntheses and opioid receptor properties of cyclic variants of cyclazocine.; Bioorganic & medicinal chemistry letters; Vol 19(2). 2009 Jan 15.
- Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.; Bioorganic & medicinal chemistry letters; Vol 19(1). 2009 Jan 1.
- Glycosyl-enkephalins: synthesis and binding at the mu, delta & kappa opioid receptors. Antinociception in mice.; Advances in experimental medicine and biology; Vol 611. 2009.
- Phenobarbital withdrawal seizures may occur over several weeks before remitting: human data and hypothetical mechanism.; Seizure; Vol 18(1). 2009 Jan.
- A novel Gbetagamma-subunit inhibitor selectively modulates mu-opioid-dependent antinociception and attenuates acute morphine-induced antinociceptive tolerance and dependence.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 28(47). 2008 Nov 19.
- In vivo characterization of (-)(-)MCL-144 and (+)(-)MCL-193: isomeric, bivalent ligands with mu/kappa agonist properties.; Neurochemical research; Vol 33(10). 2008 Oct.
- Synthesis and pharmacological evaluation of hydrophobic esters and ethers of butorphanol at opioid receptors.; Bioorganic & medicinal chemistry letters; Vol 18(16). 2008 Aug 15.
- Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine.; Bioorganic & medicinal chemistry; Vol 16(10). 2008 May 15.
- Extracellular biotransformation of beta-endorphin in rat striatum and cerebrospinal fluid.; Journal of neuroendocrinology; Vol 20(5). 2008 May.
- Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC.; Bioorganic & medicinal chemistry letters; Vol 17(23). 2007 Dec 1.
- In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors.; Bioorganic & medicinal chemistry; Vol 15(12). 2007 Jun 15.
- Synthesis and pharmacological evaluation of 6,7-indolo/thiazolo-morphinans--further SAR of levorphanol.; Journal of medicinal chemistry; Vol 50(11). 2007 May 31.
- Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.; Journal of medicinal chemistry; Vol 50(9). 2007 May 3.
- High-affinity carbamate analogues of morphinan at opioid receptors.; Bioorganic & medicinal chemistry letters; Vol 17(6). 2007 Mar 15.
- Glycosylation improves the central effects of DAMGO.; Chemical biology & drug design; Vol 69(1). 2007 Jan.