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Recent Publications

1. Donado CA
2. Theisen E
3. Zhang F
4. Nathan A
5. Fairfield ML
6. Rupani KV
7. Jones D
8. Johannes KP
9. Raychaudhuri S
10. Dwyer DF
11. Jonsson AH
12. Brenner MB
Granzyme K activates the entire complement cascade.; Nature. 2025 Feb 06.
1. Singh G
2. Kaymakcalan O
3. Hays TR
4. Abbas A
5. Sridevan S
6. Kaur J
7. Rathi S
8. Marquez J
9. Ghazizadeh S
10. Tavernier F
11. Boyce BF
12. Khan SU
13. Khan FA
14. Bui DT
15. Dagum AB
A Novel Rat Model to Simulate Positive Margins in the Wound Bed of a Resected Sarcoma.; Plastic and reconstructive surgery. Global open; Vol 12(11), pp. e6317. 2024 Nov 27.
1. Faust HJ
2. Cheng TY
3. Korsunsky I
4. Watts GFM
5. Gal-Oz ST
6. Trim WV
7. Kongthong S
8. Jonsson AH
9. Simmons DP
10. Zhang F
11. Padera R
12. Chubinskaya S
13. Wei K
14. Raychaudhuri S
15. Lynch L
16. Moody DB
17. Brenner MB
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis.; Nature communications; Vol 15(1), pp. 9859. 2024 Nov 14.
1. Yao Z
2. Ayoub A
3. Srinivasan V
4. Wu J
5. Tang C
6. Duan R
7. Milosavljevic A
8. Xing L
9. Ebetino FH
10. Frontier AJ
11. Boyce BF
Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects.; Bone research; Vol 12(1), pp. 52. 2024 Sep 05.
1. Bell RD
2. Brendel M
3. Konnaris MA
4. Xiang J
5. Otero M
6. Fontana MA
7. Bai Z
8. Krenitsky DM
9. Meednu N
10. Rangel-Moreno J
11. Scheel-Toellner D
12. Carr H
13. Nayar S
14. McMurray J
15. DiCarlo E
16. Anolik JH
17. Donlin LT
18. Orange DE
19. Kenney HM
20. Schwarz EM
21. Filer A
22. Ivashkiv LB
23. Wang F
Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue.; Nature communications; Vol 15(1), pp. 7503. 2024 Aug 29.
1. Duan R
2. Milton P
3. Sittplangkoon C
4. Liu X
5. Sui Z
6. Boyce BF
7. Yao Z
Chimeric antigen receptor dendritic cells targeted delivery of a single tumoricidal factor for cancer immunotherapy.; Cancer immunology, immunotherapy : CII; Vol 73(10), pp. 203. 2024 Aug 06.
1. Law C
2. Wacleche VS
3. Cao Y
4. Pillai A
5. Sowerby J
6. Hancock B
7. Horisberger A
8. Bracero S
9. Skidanova V
10. Li Z
11. Adejoorin I
12. Dillon E
13. Benque IJ
14. Nunez DP
15. Simmons DP
16. Keegan J
17. Chen L
18. Baker T
19. Brohawn PZ
20. Al-Mossawi H
21. Hao LY
22. Jones B
23. Rao N
24. Qu Y
25. Alves SE
26. Jonsson AH
27. Shaw KS
28. Vleugels RA
29. Massarotti E
30. Costenbader KH
31. Brenner MB
32. Lederer JA
33. Hultquist JF
34. Choi J
35. Rao DA
Publisher Correction: Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus.; Nature. 2024 Jul 26.
1. Law C
2. Wacleche VS
3. Cao Y
4. Pillai A
5. Sowerby J
6. Hancock B
7. Horisberger A
8. Bracero S
9. Skidanova V
10. Li Z
11. Adejoorin I
12. Dillon E
13. Benque IJ
14. Nunez DP
15. Simmons DP
16. Keegan J
17. Chen L
18. Baker T
19. Brohawn PZ
20. Al-Mossawi H
21. Hao LY
22. Jones B
23. Rao N
24. Qu Y
25. Alves SE
26. Jonsson AH
27. Shaw KS
28. Vleugels RA
29. Massarotti E
30. Costenbader KH
31. Brenner MB
32. Lederer JA
33. Hultquist JF
34. Choi J
35. Rao DA
Interferon subverts an AHR-JUN axis to promote CXCL13+ T cells in lupus.; Nature. 2024 Jul 10.
1. Scheller EL
2. McDonald M
3. Andersen TL
4. Sumner DR
5. Noda M
6. Erben RG
7. Boyce BF
8. Compston JE
9. Dempster DW
10. Takahashi HE
11. Malluche HH
12. Wronski TJ
Celebrating 50-years: the history and future of the International Society of Bone Morphometry.; JBMR plus; Vol 8(7), pp. ziae070. 2024 Jun 12.
1. Dunlap G
2. Wagner A
3. Meednu N
4. Wang R
5. Zhang F
6. Ekabe JC
7. Jonsson AH
8. Wei K
9. Sakaue S
10. Nathan A
11. Bykerk VP
12. Donlin LT
13. Goodman SM
14. Firestein GS
15. Boyle DL
16. Holers VM
17. Moreland LW
18. Tabechian D
19. Pitzalis C
20. Filer A
21. Raychaudhuri S
22. Brenner MB
23. Thakar J
24. McDavid A
25. Rao DA
26. Anolik JH
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium.; Nature communications; Vol 15(1), pp. 4991. 2024 Jun 11.
1. Weinand K
2. Sakaue S
3. Nathan A
4. Jonsson AH
5. Zhang F
6. Watts GFM
7. Al Suqri M
8. Zhu Z
9. Rao DA
10. Anolik JH
11. Brenner MB
12. Donlin LT
13. Wei K
14. Raychaudhuri S
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis.; Nature communications; Vol 15(1), pp. 4650. 2024 May 31.
1. Bai Z
2. Bartelo N
3. Aslam M
4. Murphy EA
5. Hale CR
6. Blachere NE
7. Parveen S
8. Spolaore E
9. DiCarlo E
10. Gravallese EM
11. Smith MH
12. Frank MO
13. Jiang CS
14. Zhang H
15. Pyrgaki C
16. Lewis MJ
17. Sikandar S
18. Pitzalis C
19. Lesnak JB
20. Mazhar K
21. Price TJ
22. Malfait AM
23. Miller RE
24. Zhang F
25. Goodman S
26. Darnell RB
27. Wang F
28. Orange DE
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis.; Science translational medicine; Vol 16(742), pp. eadk3506. 2024 Apr 10.
1. Sakaue S
2. Weinand K
3. Isaac S
4. Dey KK
5. Jagadeesh K
6. Kanai M
7. Watts GFM
8. Zhu Z
9. Brenner MB
10. McDavid A
11. Donlin LT
12. Wei K
13. Price AL
14. Raychaudhuri S
Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles.; Nature genetics. 2024 Apr 09.
1. Zhang F
2. Jonsson AH
3. Nathan A
4. Millard N
5. Curtis M
6. Xiao Q
7. Gutierrez-Arcelus M
8. Apruzzese W
9. Watts GFM
10. Weisenfeld D
11. Nayar S
12. Rangel-Moreno J
13. Meednu N
14. Marks KE
15. Mantel I
16. Kang JB
17. Rumker L
18. Mears J
19. Slowikowski K
20. Weinand K
21. Orange DE
22. Geraldino-Pardilla L
23. Deane KD
24. Tabechian D
25. Ceponis A
26. Firestein GS
27. Maybury M
28. Sahbudin I
29. Ben-Artzi A
30. Mandelin AM
31. Nerviani A
32. Lewis MJ
33. Rivellese F
34. Pitzalis C
35. Hughes LB
36. Horowitz D
37. DiCarlo E
38. Gravallese EM
39. Boyce BF
40. Moreland LW
41. Goodman SM
42. Perlman H
43. Holers VM
44. Liao KP
45. Filer A
46. Bykerk VP
47. Wei K
48. Rao DA
49. Donlin LT
50. Anolik JH
51. Brenner MB
52. Raychaudhuri S
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.; Nature; Vol 623(7987), pp. 616-624. 2023 Nov 08.
1. Li J
2. Yao Z
3. Liu X
4. Duan R
5. Yi X
6. Ayoub A
7. Sanders JO
8. Mesfin A
9. Xing L
10. Boyce BF
TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.; Nature communications; Vol 14(1), pp. 159. 2023 Jan 11.
1. Yao Z
2. Boyce BF
TGFβ priming promotes TNF-induced bone erosion: a promising new target in RA?; Nature reviews. Rheumatology. 2022 Sep 16.
1. Ajabnoor RM
2. Quinzi DA
3. Carmody E
4. Boyce BF
Intraligamentous synovial osteochondroma of the ligamentum teres: a series of 14 cases.; International journal of clinical and experimental pathology; Vol 15(7), pp. 282-288. 2022 Jul 15.
1. Nazemi AK
2. Grossi J
3. Tavernier FB
4. Boyce BF
5. Komatsu DE
6. Khan FA
Glomus Tumor of the Lower Extremity Previously Misdiagnosed as Complex Regional Pain Syndrome in Close Proximity to a Myxofibrosarcoma: A Case Report.; Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews; Vol 6(7). 2022 Jul 06.
1. Liu J
2. Zhang J
3. Lin X
4. Boyce BF
5. Zhang H
6. Xing L
Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice.; The Journal of clinical investigation; Vol 132(8). 2022 Apr 15.
1. Dong Q
2. Xiu Y
3. Wang Y
4. Hodgson C
5. Borcherding N
6. Jordan C
7. Buchanan J
8. Taylor E
9. Wagner B
10. Leidinger M
11. Holman C
12. Thiele DJ
13. O'Brien S
14. Xue HH
15. Zhao J
16. Li Q
17. Meyerson H
18. Boyce BF
19. Zhao C
HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia.; Nature communications; Vol 13(1), pp. 6107. 2022 Jan 16.
1. Lin X
2. Zhang H
3. Liu J
4. Wu CL
5. McDavid A
6. Boyce BF
7. Xing L
Aged Callus Skeletal Stem/Progenitor Cells Contain an Inflammatory Osteogenic Population With Increased IRF and NF-κB Pathways and Reduced Osteogenic Potential.; Frontiers in molecular biosciences; Vol 9. 2022.
1. Tao J
2. Srinivasan V
3. Yi X
4. Zhao Y
5. Zhang H
6. Lin X
7. Zhou X
8. Boyce BF
9. Villalta PW
10. Ebetino FH
11. Ho KK
12. Boeckman RK
13. Xing L
Bone-Targeted Bortezomib Inhibits Bortezomib-Resistant Multiple Myeloma in Mice by Providing Higher Levels of Bortezomib in Bone.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 Dec 30.
1. Zhao J
2. Xiu Y
3. Fu L
4. Dong Q
5. Borcherding N
6. Wang Y
7. Li Q
8. De Silva NS
9. Klein U
10. Boyce BF
11. Zhao C
TIFAB accelerates MLL-AF9-Induced acute myeloid leukemia through upregulation of HOXA9.; iScience; Vol 24(12). 2021 Dec 17.
1. Catheline SE
2. Bell RD
3. Oluoch LS
4. James MN
5. Escalera-Rivera K
6. Maynard RD
7. Chang ME
8. Dean C
9. Botto E
10. Ketz JP
11. Boyce BF
12. Zuscik MJ
13. Jonason JH
IKKβ-NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice.; Science signaling; Vol 14(701). 2021 Sep 21.
1. Cole CL
2. Bachman JF
3. Ye J
4. Murphy J
5. Gerber SA
6. Beck CA
7. Boyce BF
8. Muthukrishnan G
9. Chakkalakal JV
10. Schwarz EM
11. Linehan D
Increased myocellular lipid and IGFBP-3 expression in a pre-clinical model of pancreatic cancer-related skeletal muscle wasting.; Journal of cachexia, sarcopenia and muscle. 2021 May 07.
1. Kronman H
2. Torres-Berrío A
3. Sidoli S
4. Issler O
5. Godino A
6. Ramakrishnan A
7. Mews P
8. Lardner CK
9. Parise EM
10. Walker DM
11. van der ZY
12. Browne CJ
13. Boyce BF
14. Neve R
15. Garcia BA
16. Shen L
17. Peña CJ
18. Nestler EJ
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons.; Nat Neurosci.; Vol 21 ;24(5). 2021 Jan 01.
1. Lin X
2. Wang W
3. McDavid A
4. Xu H
5. Boyce BF
6. Xing L
The E3 ubiquitin ligase Itch limits the progression of post-traumatic osteoarthritis in mice by inhibiting macrophage polarization.; Osteoarthritis and cartilage. 2021 Apr 30.
1. Li L
2. Mustahsan VM
3. He G
4. Tavernier FB
5. Singh G
6. Boyce BF
7. Khan F
8. Kao I
Classification of Soft Tissue Sarcoma Specimens with Raman Spectroscopy as Smart Sensing Technology.; Cyborg and bionic systems (Washington, D.C.); Vol 2021, pp. 9816913. 2021 Jan 06.
1. Yao Z
2. Xing L
3. Boyce BF
RANKL-Based Osteoclastogenic Assay from Murine Bone Marrow Cells.; Methods in molecular biology (Clifton, N.J.); Vol 2230. 2021.
1. Masters EA
2. Hao SP
3. Mark Kenney H
4. Morita Y
5. Galloway CA
6. de Mesy Bentley KL
7. Ricciardi BF
8. Boyce BF
9. Schwarz EM
10. Oh I
Distinct Vasculotropic vs. Osteotropic Features of S. agalactiae vs. S. aureus Implant-Associated Bone Infection in Mice.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2020 Dec 18.
1. Sun S
2. Tao J
3. Sedghizadeh PP
4. Cherian P
5. Junka AF
6. Sodagar E
7. Xing L
8. Boeckman RK
9. Srinivasan V
10. Yao Z
11. Boyce BF
12. Lipe B
13. Neighbors JD
14. Russell G
15. McKenna CE
16. Ebetino FH
Bisphosphonates for delivering drugs to bone.; British journal of pharmacology. 2020 Sep 02.
1. Zhang F
2. Mears JR
3. Shakib L
4. Beynor JI
5. Shanaj S
6. Korsunsky I
7. Nathan A
8. Donlin LT
9. Raychaudhuri S
IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation.; bioRxiv : the preprint server for biology. 2020 Aug 05.
1. Qiu B
2. Joo P
3. Ajabnoor R
4. Boyce B
5. Mesfin A
Surgical management of aggressive hemangiomas of the spine.; Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia; Vol 78. 2020 Aug.
1. Lin X
2. Zhang H
3. Boyce BF
4. Xing L
Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH.; The Journal of biological chemistry. 2020 Jun 25.
1. Xing L
2. Ebetino FH
3. Boeckman RK
4. Srinivasan V
5. Tao J
6. Sawyer TK
7. Li J
8. Yao Z
9. Boyce BF
Targeting anti-cancer agents to bone using bisphosphonates.; Bone. 2020 Jun 22.
1. Lei W
2. Duan R
3. Li J
4. Liu X
5. Huston A
6. Boyce BF
7. Yao Z
The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice.; Scientific reports; Vol 10(1). 2020 Apr 24.
1. Wei K
2. Korsunsky I
3. Marshall JL
4. Gao A
5. Watts GFM
6. Major T
7. Croft AP
8. Watts J
9. Blazar PE
10. Lange JK
11. Thornhill TS
12. Filer A
13. Raza K
14. Donlin LT
15. Siebel CW
16. Buckley CD
17. Raychaudhuri S
18. Brenner MB
Notch signalling drives synovial fibroblast identity and arthritis pathology.; Nature. 2020 Apr 22.
1. Li J
2. Yi X
3. Yao Z
4. Chakkalakal JV
5. Xing L
6. Boyce BF
TNF receptor-associated factor 6 mediates TNFα-induced skeletal muscle atrophy in mice during aging.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Apr 08.
1. Dong Q
2. Xiu Y
3. Bossler A
4. Syrbu S
5. Wang H
6. Xue W
7. Zhao J
8. Li Q
9. Jin M
10. Wang L
11. Boyce B
12. Sakr H
13. Ansari MQ
14. Zhao C
CLL dedifferentiation to clonally related myeloid cells.; Blood advances; Vol 4(24). 2020 Jan 22.
1. Xiu Y
2. Dong Q
3. Fu L
4. Bossler A
5. Tang X
6. Boyce B
7. Borcherding N
8. Leidinger M
9. Sardina JL
10. Xue HH
11. Li Q
12. Feldman A
13. Aifantis I
14. Boccalatte F
15. Wang L
16. Jin M
17. Khoury J
18. Wang W
19. Hu S
20. Yuan Y
21. Wang E
22. Yuan J
23. Janz S
24. Colgan J
25. Habelhah H
26. Waldschmidt T
27. Müschen M
28. Bagg A
29. Darbro B
30. Zhao C
Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion.; Blood; Vol 135(2). 2020 Jan 09.
1. Wang W
2. Wang H
3. Zhou X
4. Li X
5. Sun W
6. Dellinger M
7. Boyce BF
8. Xing L
Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 34(11). 2019 Nov.
1. Wang H
2. Zhang H
3. Srinivasan V
4. Tao J
5. Sun W
6. Lin X
7. Wu T
8. Boyce BF
9. Ebetino FH
10. Boeckman RK
11. Xing L
Targeting Bortezomib to Bone Increases its Bone Anabolic Activity and Reduces Systemic Adverse Effects in Mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2019 Oct 14.
1. Liang Q
2. Zhang L
3. Wood RW
4. Ji RC
5. Boyce BF
6. Schwarz EM
7. Wang Y
8. Xing L
RelB regulates lymphatic endothelial cells during vessel maturation and is required for lymphatic vessel function in adult mice.; The American journal of pathology. 2019 Sep 17.
1. Li J
2. Ayoub A
3. Xiu Y
4. Yin X
5. Sanders JO
6. Mesfin A
7. Xing L
8. Yao Z
9. Boyce BF
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.; Nature communications; Vol 10(1). 2019 Jun 26.
1. Zhang F
2. Wei K
3. Slowikowski K
4. Fonseka CY
5. Rao DA
6. Kelly S
7. Goodman SM
8. Tabechian D
9. Hughes LB
10. Salomon-Escoto K
11. Watts GFM
12. Jonsson AH
13. Rangel-Moreno J
14. Meednu N
15. Rozo C
16. Apruzzese W
17. Eisenhaure TM
18. Lieb DJ
19. Boyle DL
20. Mandelin AM
21. Boyce BF
22. DiCarlo E
23. Gravallese EM
24. Gregersen PK
25. Moreland L
26. Firestein GS
27. Hacohen N
28. Nusbaum C
29. Lederer JA
30. Perlman H
31. Pitzalis C
32. Filer A
33. Holers VM
34. Bykerk VP
35. Donlin LT
36. Anolik JH
37. Brenner MB
38. Raychaudhuri S
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.; Nature immunology. 2019 May 06.
1. Masters EA
2. Trombetta RP
3. de Mesy Bentley KL
4. Boyce BF
5. Gill AL
6. Gill SR
7. Nishitani K
8. Ishikawa M
9. Morita Y
10. Ito H
11. Bello-Irizarry SN
12. Ninomiya M
13. Brodell JD
14. Lee CC
15. Hao SP
16. Oh I
17. Xie C
18. Awad HA
19. Daiss JL
20. Owen JR
21. Kates SL
22. Schwarz EM
23. Muthukrishnan G
Evolving concepts in bone infection: redefining "biofilm", "acute vs. chronic osteomyelitis", "the immune proteome" and "local antibiotic therapy".; Bone research; Vol 7. 2019.
1. Sun W
2. Meednu N
3. Rosenberg A
4. Rangel-Moreno J
5. Wang V
6. Glanzman J
7. Owen T
8. Zhou X
9. Zhang H
10. Boyce BF
11. Anolik JH
12. Xing L
B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation.; Nature communications; Vol 9(1). 2018 Dec 03.
1. Wang H
2. Xiao L
3. Tao J
4. Srinivasan V
5. Boyce BF
6. Ebetino FH
7. Oyajobi BO
8. Boeckman RK
9. Xing L
Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice.; Pharmaceutics; Vol 10(3). 2018 Sep 10.
1. D'Amore T
2. Boyce B
3. Mesfin A
Chordoma of the mobile spine and sacrum: clinical management and prognosis.; Journal of spine surgery (Hong Kong); Vol 4(3). 2018 Sep.
1. Donlin LT
2. Rao DA
3. Wei K
4. Slowikowski K
5. McGeachy MJ
6. Turner JD
7. Meednu N
8. Mizoguchi F
9. Gutierrez-Arcelus M
10. Lieb DJ
11. Keegan J
12. Muskat K
13. Hillman J
14. Rozo C
15. Ricker E
16. Eisenhaure TM
17. Li S
18. Browne EP
19. Chicoine A
20. Sutherby D
21. Noma A
22. Nusbaum C
23. Kelly S
24. Pernis AB
25. Ivashkiv LB
26. Goodman SM
27. Robinson WH
28. Utz PJ
29. Lederer JA
30. Gravallese EM
31. Boyce BF
32. Hacohen N
33. Pitzalis C
34. Gregersen PK
35. Firestein GS
36. Raychaudhuri S
37. Moreland LW
38. Holers VM
39. Bykerk VP
40. Filer A
41. Boyle DL
42. Brenner MB
43. Anolik JH
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue; Arthritis research & therapy; Vol 20(1). 2018 Jul 11.