Recent Publications
Recent Publications
- Reevaluating Anti-Inflammatory Therapy: Targeting Senescence to Balance Anti-Cancer Efficacy and Vascular Disease.; Arteriosclerosis, thrombosis, and vascular biology. 2025 Jan 16.
- Energy metabolism in osteoprogenitors and osteoblasts: role of the Pentose Phosphate Pathway.; The Journal of biological chemistry. 2024 Nov 26.
- PPARγ drives mitochondrial stress signaling and the loss of atrial cardiomyocytes in newborn mice exposed to hyperoxia.; Redox biology; Vol 76, pp. 103351. 2024 Sep 12.
- A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria.; eLife; Vol 12. 2024 Jul 31.
- Manipulating mitochondrial pyruvate carrier function causes metabolic remodeling in corneal myofibroblasts that ameliorates fibrosis.; Redox biology; Vol 75, pp. 103235. 2024 Jun 08.
- Coordinated metabolic responses to cyclophilin D deletion in the developing heart.; iScience; Vol 27(3), pp. 109157. 2024 Feb 09.
- Reactive oxygen species generation by reverse electron transfer at mitochondrial complex I under simulated early reperfusion conditions.; Redox biology; Vol 70, pp. 103047. 2024 Jan 27.
- A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria.; bioRxiv : the preprint server for biology. 2023 Sep 05.
- Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology.; JACC. Basic to translational science; Vol 8(9), pp. 1141-1156. 2023 Jun 14.
- ROLE OF THE MITOCHONDRIAL PERMEABILITY TRANSITION IN BONE METABOLISM AND AGING.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2023 Feb 13.
- Reactive Oxygen Species Generation by Reverse Electron Transfer at Mitochondrial Complex I Under Simulated Early Reperfusion Conditions.; bioRxiv : the preprint server for biology. 2023 Jan 21.
- Dysregulation of bile acids, lipids, and nucleotides in psoriatic arthritis revealed by unbiased profiling of serum metabolites.; Arthritis & rheumatology (Hoboken, N.J.). 2022 Jul 11.
- Inhibiting Succinate Release Worsens Cardiac Reperfusion Injury by Enhancing Mitochondrial Reactive Oxygen Species Generation.; Journal of the American Heart Association. 2022 Jun 29.
- Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion.; Journal of molecular and cellular cardiology; Vol 174, pp. 101-114. 2022 Jan 05.
- Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation.; Redox biology; Vol 47. 2021 Sep 20.
- Metabolomics of aging in primary fibroblasts from small and large breed dogs.; GeroScience. 2021 Jun 16.
- Neonatal hyperoxia inhibits proliferation and survival of atrial cardiomyocytes by suppressing fatty acid synthesis.; JCI insight. 2021 Jan 28.
- FNDC-1-Mediated Mitophagy and ATFS-1 Coordinate to Protect Against Hypoxia-Reoxygenation.; Autophagy. 2021 Jan 08.
- Modified Blue Native Gel Approach for Analysis of Respiratory Supercomplexes.; Methods in molecular biology (Clifton, N.J.); Vol 2276. 2021.
- Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity.; ChemMedChem. 2020 Dec 16.
- Acid enhancement of ROS generation by complex-I reverse electron transport is balanced by acid inhibition of complex-II: Relevance for tissue reperfusion injury.; Redox biology; Vol 37. 2020 Sep 19.
- ALKBH7 mediates necrosis via rewiring of glyoxal metabolism.; eLife; Vol 9. 2020 Aug 14.
- Amber Alert: Getting to the Heart of Succinate Efflux in Reperfusion Injury.; Cardiovascular research. 2020 Jul 14.
- The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function.; Nature communications; Vol 11(1). 2020 Jul 13.
- Cardiac metabolism as a driver and therapeutic target of myocardial infarction.; Journal of cellular and molecular medicine. 2020 May 08.
- Cardiac Function is not Susceptible to Moderate Disassembly of Mitochondrial Respiratory Supercomplexes.; International journal of molecular sciences; Vol 21(5). 2020 Feb 25.
- Swapping mitochondria: A key to understanding susceptibility to neonatal chronic lung disease.; American journal of physiology. Lung cellular and molecular physiology. 2019 Oct 09.
- Fndc-1 contributes to paternal mitochondria elimination in C. elegans.; Developmental biology; Vol 454(1). 2019 Oct 01.
- Cellular Compartmentation and the Redox/Nonredox Functions of NAD.; Antioxidants & redox signaling; Vol 31(9). 2019 Sep 20.
- Early life exposures shape the CD4+ T cell transcriptome, influencing proliferation, differentiation, and mitochondrial dynamics later in life.; Scientific reports; Vol 9(1). 2019 Aug 07.
- Cardioprotection by the mitochondrial unfolded protein response requires ATF5.; American journal of physiology. Heart and circulatory physiology; Vol 317(2). 2019 Aug 01.
- Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH.; Journal of molecular and cellular cardiology. 2018 Jun 26.
- Cardiac metabolic effects of KNa1.2 channel deletion and evidence for its mitochondrial localization.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Jun 04.
- Accumulation of Succinate in Cardiac Ischemia Primarily Occurs via Canonical Krebs Cycle Activity.; Cell reports; Vol 23(9). 2018 May 29.
- Metabolomics reveals critical adrenergic regulatory checkpoints in glycolysis and pentose-phosphate pathways in embryonic heart.; The Journal of biological chemistry; Vol 293(18). 2018 May 04.
- Krebs cycle metabolites and preferential succinate oxidation following neonatal hypoxic-ischemic brain injury in mice.; Pediatric research; Vol 83(2). 2018 Feb.
- SMG-1 kinase attenuates mitochondrial ROS production but not cell respiration deficits during hyperoxia.; Experimental lung research. 2017 Jul 27.
- Synthesis and Antineoplastic Evaluation of Mitochondrial Complex II (Succinate Dehydrogenase) Inhibitors Derived from Atpenin A5.; ChemMedChem; Vol 12(13). 2017 Jul 06.
- Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.; The Biochemical journal. 2017 Jul 03.
- The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection.; The Biochemical journal; Vol 474(12). 2017 Jun 09.
- Metabolism: A Direct Link Between Cardiac Structure and Function.; Circulation; Vol 136(22). 2017 Jan 28.
- Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury.; Cell metabolism; Vol 24(4). 2016 Oct 11.
- Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.; The Journal of biological chemistry; Vol 291(38). 2016 Sep 16.
- Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.; Anesthesiology; Vol 124(5). 2016 May.
- Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy.; Circulation research; Vol 118(5). 2016 Mar 4.
- The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury.; Journal of cardiovascular pharmacology and therapeutics; Vol 21(2). 2016 Mar.
- The Mitochondrial Unfolded Protein Response Protects against Anoxia in Caenorhabditis elegans.; PloS one; Vol 11(7). 2016.
- Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone.; PloS one; Vol 11(5). 2016.
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).; Autophagy; Vol 12(1). 2016.
- The cardioprotective compound cloxyquin uncouples mitochondria and induces autophagy.; American journal of physiology. Heart and circulatory physiology; Vol 310(1). 2016 Jan 1.