URMC / Labs / Calvi Lab / Publications

Recent Publications

1. Ho TC
2. LaMere MW
3. Kawano H
4. Byun DK
5. LaMere EA
6. Chiu YC
7. Chen C
8. Wang J
9. Dokholyan NV
10. Calvi LM
11. Liesveld JL
12. Jordan CT
13. Kapur R
14. Singh RK
15. Becker MW
Targeting IL-1/IRAK1/4 signaling in Acute Myeloid Leukemia Stem Cells Following Treatment and Relapse.; bioRxiv : the preprint server for biology. 2024 Nov 11.
1. Hughson AL
2. Hannon G
3. Salama NA
4. Vrooman TG
5. Stockwell CA
6. Mills BN
7. Garrett-Larsen J
8. Qiu H
9. Katerji R
10. Benoodt L
11. Johnston CJ
12. Murphy JD
13. Kruger E
14. Ye J
15. Gavras NW
16. Keeley DC
17. Qin SS
18. Lesch ML
19. Muhitch JB
20. Love TMT
21. Calvi LM
22. Lord EM
23. Luheshi N
24. Elyes J
25. Linehan DC
26. Gerber SA
Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.; Molecular therapy. Nucleic acids; Vol 35(4), pp. 102350. 2024 Sep 30.
1. Lee K
2. Dissanayake W
3. MacLiesh M
4. Hong CL
5. Yin Z
6. Kawano Y
7. Kaszuba CM
8. Kawano H
9. Quarato ER
10. Marples B
11. Becker M
12. Bajaj J
13. Calvi LM
14. Yeh SA
Ultralow-dose irradiation enables engraftment and intravital tracking of disease initiating niches in clonal hematopoiesis.; Scientific reports; Vol 14(1), pp. 20486. 2024 Sep 03.
1. Quarato ER
2. Salama NA
3. Calvi LM
Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging.; Current osteoporosis reports. 2024 May 23.
1. Rodems BJ
2. Sharma S
3. Baker CD
4. Kaszuba CM
5. Ito T
6. Liesveld JL
7. Calvi LM
8. Becker MW
9. Jordan CT
10. Ashton JM
11. Bajaj J
Temporal Single Cell Analysis of Leukemia Microenvironment Identifies Taurine-Taurine Transporter Axis as a Key Regulator of Myeloid Leukemia.; bioRxiv : the preprint server for biology. 2024 May 14.
1. Kfoury YS
2. Ji F
3. Jain E
4. Mazzola MC
5. Schiroli G
6. Papazian A
7. Mercier FE
8. Sykes DB
9. Kiem A
10. Randolph MA
11. Abdel-Wahab OI
12. Calvi LM
13. Sadreyev R
14. Scadden DT
The bone marrow stroma in human myelodysplastic syndrome reveals alterations that regulate disease progression.; Blood advances. 2023 Jul 14.
1. Quarato ER
2. Salama NA
3. Li AJ
4. Smith CO
5. Zhang J
6. Kawano Y
7. McArthur M
8. Liesveld JL
9. Becker MW
10. Elliott MR
11. Eliseev RA
12. Calvi LM
Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling.; Cell death & disease; Vol 14(7), pp. 428. 2023 Jul 14.
1. Khazan N
2. Quarato ER
3. Singh NA
4. Snyder CWA
5. Moore T
6. Miller JP
7. Yasui M
8. Teramoto Y
9. Goto T
10. Reshi S
11. Hong J
12. Zhang N
13. Pandey D
14. Srivastava P
15. Morell A
16. Kawano H
17. Kawano Y
18. Conley T
19. Sahasrabudhe DM
20. Yano N
21. Miyamoto H
22. Aljitawi O
23. Liesveld J
24. Becker MW
25. Calvi LM
26. Zhovmer AS
27. Tabdanov ED
28. Dokholyan NV
29. Linehan DC
30. Hansen JN
31. Gerber SA
32. Sharon A
33. Khera MK
34. Jurutka PW
35. Rochel N
36. Kim KK
37. Rowswell-Turner RB
38. Singh RK
39. Moore RG
Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1.; Cancers; Vol 15(13). 2023 Jun 30.
1. Kawano H
2. Kawano Y
3. Yu C
4. LaMere MW
5. McArthur MJ
6. Becker MW
7. Ballinger SW
8. Gojo S
9. Eliseev RA
10. Calvi LM
Mitochondrial Transfer to Host Cells from Ex Vivo Expanded Donor Hematopoietic Stem Cells.; Cells; Vol 12(11). 2023 May 25.
1. Kawano Y
2. Kawano H
3. Ghoneim D
4. Fountaine TJ
5. Byun DK
6. LaMere MW
7. Mendler JH
8. Ho T
9. Salama NA
10. Myers JR
11. Hussein SE
12. Frisch BJ
13. Ashton JM
14. Azadniv M
15. Liesveld JL
16. Kfoury Y
17. Scadden DT
18. Becker MW
19. Calvi LM
Myelodysplastic syndromes disable human CD271 + VCAM1 + CD146 + niches supporting normal hematopoietic stem/progenitor cells.; bioRxiv : the preprint server for biology. 2023 Apr 10.
1. Zhang H
2. Liesveld JL
3. Calvi LM
4. Lipe BC
5. Xing L
6. Becker MW
7. Schwarz EM
8. Yeh SA
The roles of bone remodeling in normal hematopoiesis and age-related hematological malignancies.; Bone research; Vol 11(1), pp. 15. 2023 Mar 14.
1. Kaszuba CM
2. Rodems BJ
3. Sharma S
4. Franco EI
5. Ashton JM
6. Calvi LM
7. Bajaj J
Identifying Bone Marrow Microenvironmental Populations in Myelodysplastic Syndrome and Acute Myeloid Leukemia.; Journal of visualized experiments : JoVE. 2023 Jan 10.
1. Hughson AL
2. Hannon G
3. Salama NA
4. Vrooman TG
5. Stockwell CA
6. Mills BN
7. Garrett-Larsen J
8. Qiu H
9. Katerji R
10. Benoodt L
11. Johnston CJ
12. Murphy JD
13. Kruger E
14. Ye J
15. Gavras NW
16. Keeley DC
17. Qin SS
18. Lesch ML
19. Muhitch JB
20. Love TMT
21. Calvi LM
22. Lord EM
23. Luheshi N
24. Elyes J
25. Linehan DC
26. Gerber SA
Local Delivery of SBRT and IL12 by mRNA Technology Overcomes Immunosuppressive Barriers to Eliminate Pancreatic Cancer.; bioRxiv : the preprint server for biology. 2023 Jan 02.
1. Lynch OF
2. Calvi LM
Immune Dysfunction, Cytokine Disruption, and Stromal Changes in Myelodysplastic Syndrome: A Review.; Cells; Vol 11(3). 2022 Feb 08.
1. Ruffolo LI
2. Jackson KM
3. Kuhlers PC
4. Dale BS
5. Figueroa Guilliani NM
6. Ullman NA
7. Burchard PR
8. Qin SS
9. Juviler PG
10. Keilson JM
11. Morrison AB
12. Georger M
13. Jewell R
14. Calvi LM
15. Nywening TM
16. O'Dell MR
17. Hezel AF
18. De Las Casas L
19. Lesinski GB
20. Yeh JJ
21. Hernandez-Alejandro R
22. Belt BA
23. Linehan DC
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity.; Gut. 2021 Aug 19.
1. Saunders J
2. Niswander LM
3. McGrath KE
4. Koniski A
5. Catherman SC
6. Ture SK
7. Medhora M
8. Kingsley PD
9. Calvi LM
10. Williams JP
11. Morrell CN
12. Palis J
Long-acting PGE2 and Lisinopril Mitigate H-ARS.; Radiation research. 2021 Jun 21.
1. Ackun-Farmmer MA
2. Soto CA
3. Lesch ML
4. Byun D
5. Yang L
6. Calvi LM
7. Benoit DSW
8. Frisch BJ
Reduction of leukemic burden via bone-targeted nanoparticle delivery of an inhibitor of C-chemokine (C-C motif) ligand 3 (CCL3) signaling.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 35(4). 2021 Apr.
1. Seyfried AN
2. McCabe A
3. Smith JNP
4. Calvi LM
5. MacNamara KC
CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia.; Leukemia. 2021 Mar 20.
1. Calvi LM
FGF-23: a novel actor in stem cell mobilization.; Blood; Vol 137(11). 2021 Mar 18.
1. Calvi LM
Improved in vivo Experimental Screening Identifies an Anabolic Analog of 1,25 Dihydroxyvitamin D3 With Minimal Bone Resorption Activity.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Jan 06.
1. Calvi LM
2. Li AJ
3. Becker MW
What is the role of the microenvironment in MDS?; Best practice & research. Clinical haematology; Vol 32(4). 2019 Dec.
1. Azadniv M
2. Myers JR
3. McMurray HR
4. Guo N
5. Rock P
6. Coppage ML
7. Ashton J
8. Becker MW
9. Calvi LM
10. Liesveld JL
Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support.; Leukemia. 2019 Sep 06.
1. Calvi LM
2. Frisch BJ
3. Kingsley PD
4. Koniski AD
5. Love TM
6. Williams JP
7. Palis J
Acute and late effects of combined internal and external radiation exposures on the hematopoietic system.; International journal of radiation biology. 2019 Jul 30.
1. Banerjee T
2. Calvi LM
3. Becker MW
4. Liesveld JL
Flaming and fanning: The Spectrum of inflammatory influences in myelodysplastic syndromes.; Blood reviews; Vol 36. 2019 Jul.
1. Calvi LM
2. Hofbauer LC
A Novel Strategy for Repairing Multiple Myeloma Bone Lesions: Lessons From Murine Models.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 34(5). 2019 May.
1. Frisch BJ
2. Hoffman CM
3. Latchney SE
4. LaMere MW
5. Myers J
6. Ashton J
7. Li AJ
8. Saunders J
9. Palis J
10. Perkins AS
11. McCabe A
12. Smith JN
13. McGrath KE
14. Rivera-Escalera F
15. McDavid A
16. Liesveld JL
17. Korshunov VA
18. Elliott MR
19. MacNamara KC
20. Becker MW
21. Calvi LM
Aged marrow macrophages expand platelet-biased hematopoietic stem cells via Interleukin1B.; JCI insight; Vol 5. 2019 Apr 18.
1. Ayoub E
2. Wilson MP
3. McGrath KE
4. Li AJ
5. Frisch BJ
6. Palis J
7. Calvi LM
8. Zhang Y
9. Perkins AS
EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription.; Nature communications; Vol 9(1). 2018 Oct 12.
1. Staversky RJ
2. Byun DK
3. Georger MA
4. Zaffuto BJ
5. Goodman A
6. Becker MW
7. Calvi LM
8. Frisch BJ
The Chemokine CCL3 Regulates Myeloid Differentiation and Hematopoietic Stem Cell Numbers.; Scientific reports; Vol 8(1). 2018 Oct 02.
1. Hoffman CM
2. Han J
3. Calvi LM
Impact of aging on bone, marrow and their interactions.; Bone. 2018 Jul 16.
1. Li AJ
2. Calvi LM
The microenvironment in myelodysplastic syndromes: niche-mediated disease initiation and progression.; Experimental hematology. 2017 Aug 18.
1. Lawal RA
2. Zhou X
3. Batey K
4. Hoffman CM
5. Georger MA
6. Radtke F
7. Hilton MJ
8. Xing L
9. Frisch BJ
10. Calvi LM
The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 32(6). 2017 Jun.
1. Oleksyn D
2. Zhao J
3. Vosoughi A
4. Zhao JC
5. Misra R
6. Pentland AP
7. Ryan D
8. Anolik J
9. Ritchlin C
10. Looney J
11. Anandarajah AP
12. Schwartz G
13. Calvi LM
14. Georger M
15. Mohan C
16. Sanz I
17. Chen L
PKK deficiency in B cells prevents lupus development in Sle lupus mice.; Immunology letters; Vol 185. 2017 Mar 06.
1. Latchney SE
2. Calvi LM
The aging hematopoietic stem cell niche: Phenotypic and functional changes and mechanisms that contribute to hematopoietic aging.; Seminars in hematology; Vol 54(1). 2017 Jan.
1. Lee CC
2. Kimmell KT
3. Lalonde A
4. Salzman P
5. Miller MC
6. Calvi LM
7. Manuylova E
8. Shafiq I
9. Edward Vates G
Geographic variation in cost of care for pituitary tumor surgery.; Pituitary; Vol 19(5). 2016 Oct.
1. Balderman SR
2. Li AJ
3. Hoffman CM
4. Frisch BJ
5. Goodman AN
6. LaMere MW
7. Georger MA
8. Evans AG
9. Liesveld JL
10. Becker MW
11. Calvi LM
Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome.; Blood; Vol 127(5). 2016 Feb 4.
1. Manuylova E
2. Calvi LM
3. Hastings C
4. Vates GE
5. Johnson MD
6. Cave WT
7. Shafiq I
Late presentation of acromegaly in medically controlled prolactinoma patients.; Endocrinology, diabetes & metabolism case reports; Vol 2016. 2016.
1. Calvi LM
2. Link DC
The hematopoietic stem cell niche in homeostasis and disease.; Blood; Vol 126(22). 2015 Nov 26.
1. Manuylova E
2. Calvi LM
3. Vates GE
4. Hastings C
5. Shafiq I
MORNING SERUM CORTISOL LEVEL AFTER TRANSSPHENOIDAL SURGERY FOR PITUITARY ADENOMA PREDICTS HYPOTHALAMIC-PITUITARY-ADRENAL FUNCTION DESPITE INTRAOPERATIVE DEXAMETHASONE USE.; Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists; Vol 21(8). 2015 Aug.
1. Hutchinson K
2. Jahangiri S
3. Calvi LM
4. Barr P
5. Friedberg JW
6. Kelly JL
Impact of dietary supplements, obesity and treatment initiation on serum vitamin D levels in patients with lymphoma.; Leukemia & lymphoma; Vol 56(2). 2015 Feb.
1. Sivagnanalingam U
2. Balys M
3. Eberhardt A
4. Wang N
5. Myers JR
6. Ashton JM
7. Becker MW
8. Calvi LM
9. Mendler JH
Residual Disease in a Novel Xenograft Model of RUNX1-Mutated, Cytogenetically Normal Acute Myeloid Leukemia.; PloS one; Vol 10(7). 2015.
1. Evans AG
2. Calvi LM
Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis.; Annals of the New York Academy of Sciences; Vol 1335. 2015 Jan.
1. Balderman SR
2. Calvi LM
Biology of BM failure syndromes: role of microenvironment and niches.; Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program; Vol 2014(1). 2014 Dec 5.
1. Hoffman CM
2. Calvi LM
Minireview: complexity of hematopoietic stem cell regulation in the bone marrow microenvironment.; Molecular endocrinology (Baltimore, Md.); Vol 28(10). 2014 Oct.
1. Frisch BJ
2. Calvi LM
Osteoblasts as leukemia-initiating cells.; Bonekey reports; Vol 3. 2014.
1. Calvi LM
2. Link DC
Cellular complexity of the bone marrow hematopoietic stem cell niche.; Calcified tissue international; Vol 94(1). 2014 Jan.
1. Frisch BJ
2. Calvi LM
Hematopoietic stem cell cultures and assays.; Methods in molecular biology (Clifton, N.J.); Vol 1130. 2014.
1. Li JY
2. Adams J
3. Calvi LM
4. Lane TF
5. Weitzmann MN
6. Pacifici R
Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B.; Blood; Vol 122(14). 2013 Oct 3.
1. Calvi LM
Osteolineage cells and regulation of the hematopoietic stem cell.; Best practice & research. Clinical haematology; Vol 26(3). 2013 Sep.
1. Smith JN
2. Calvi LM
Concise review: Current concepts in bone marrow microenvironmental regulation of hematopoietic stem and progenitor cells.; Stem cells (Dayton, Ohio); Vol 31(6). 2013 Jun.
1. Yeaney GA
2. Brathwaite JM
3. Dashnaw ML
4. Vates GE
5. Calvi LM
Pituitary adenoma with mucin cells in a man with an unusual presentation of Carney complex.; Endocrine pathology; Vol 24(2). 2013 Jun.