URMC / Labs / Elder Lab / Publications Recent Publications Morgan SERomanick SSDeLouise LMcGrath JElder A Understanding Human Health Impacts Following Microplastic Exposure Necessitates Standardized Protocols.; Current protocols; Vol 4(7), pp. e1104. 2024 Jul. Hussain RGraham UElder ANedergaard M Air pollution, glymphatic impairment, and Alzheimer's disease.; Trends in neurosciences. 2023 Sep 28. Borm PJALison DDriscoll KDuffin RHarkema JWeber KElder A Inflammation as a Key Outcome Pathway in Particle Induced Effects in the Lung.; Frontiers in public health; Vol 10. 2022. Keller JGGraham UMKoltermann-Jülly JGelein RMa-Hock LLandsiedel RWiemann MOberdörster GElder AWohlleben W Author Correction: Predicting dissolution and transformation of inhaled nanoparticles in the lung using abiotic flow cells: The case of barium sulphate.; Scientific reports; Vol 11(1). 2021 Apr 19. Herr DJew KWong CKennell AGelein RChalupa DRaab AOberdörster GOlschowka JO'Banion MKElder A Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model.; Neurotoxicology. 2021 Mar 29. Knudsen TBFitzpatrick SCDe Abrew KNBirnbaum LSChappelle ADaston GPDolinoy DCElder AEuling SFaustman EMFedinick KPFranzosa JAHaggard DEHaws LKleinstreuer NLouis GMBMendrick DLRudel RSaili KSSchug TTTanguay RLTurley AEWetmore BAWhite KWZurlinden TJ FutureTox IV Workshop Summary: Predictive Toxicology for Healthy Children.; Toxicological sciences : an official journal of the Society of Toxicology. 2021 Feb 08. Smyth TVeazey JEliseeva SChalupa DElder AGeoras SN Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin.; Particle and fibre toxicology; Vol 17(1). 2020 Oct 15. Keller JGGraham UMKoltermann-Jülly JGelein RMa-Hock LLandsiedel RWiemann MOberdörster GElder AWohlleben W Predicting dissolution and transformation of inhaled nanoparticles in the lung using abiotic flow cells: The case of barium sulfate.; Scientific reports; Vol 10(1). 2020 Jan 16. Jew KHerr DWong CKennell AMorris-Schaffer KOberdörster GO'Banion MKCory-Slechta DAElder A Selective memory and behavioral alterations after ambient ultrafine particulate matter exposure in aged 3xTgAD Alzheimer's disease mice.; Particle and fibre toxicology; Vol 16(1). 2019 Nov 26. Riediker MZink DKreyling WOberdörster GElder AGraham ULynch IDuschl AIchihara GIchihara SKobayashi THisanaga NUmezawa MCheng TJHandy RGulumian MTinkle SCassee F Correction to: Particle toxicology and health - where are we?; Particle and fibre toxicology; Vol 16(1). 2019 Jun 27. Riediker MZink DKreyling WOberdörster GElder AGraham ULynch IDuschl AIchihara GIchihara SKobayashi THisanaga NUmezawa MCheng TJHandy RGulumian MTinkle SCassee F Particle toxicology and health - where are we?; Particle and fibre toxicology; Vol 16(1). 2019 Apr 23. Morris-Schaffer KMerrill AJew KWong CConrad KHarvey KMarvin ESobolewski MOberdörster GElder ACory-Slechta DA Effects of neonatal inhalation exposure to ultrafine carbon particles on pathology and behavioral outcomes in C57BL/6J mice.; Particle and fibre toxicology; Vol 16(1). 2019 Feb 18. Stone VMiller MRClift MJDElder AMills NLMøller PSchins RPFVogel UKreyling WGAlstrup Jensen KKuhlbusch TAJSchwarze PEHoet PPietroiusti ADe Vizcaya-Ruiz ABaeza-Squiban ATeixeira JPTran CLCassee FR Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge.; Environmental health perspectives; Vol 125(10). 2017 Oct 10. Shi Mde Mesy Bentley KLPalui GMattoussi HElder AYang H The roles of surface chemistry, dissolution rate, and delivered dose in the cytotoxicity of copper nanoparticles.; Nanoscale; Vol 9(14). 2017 Apr 06. Graham UMJacobs GYokel RADavis BHDozier AKBirch METseng MTOberdörster GElder ADeLouise L From Dose to Response: In Vivo Nanoparticle Processing and Potential Toxicity.; Advances in experimental medicine and biology; Vol 947. 2017. McCarthy CEDuffney PFGelein RThatcher THElder APhipps RPSime PJ Dung biomass smoke activates inflammatory signaling pathways in human small airway epithelial cells.; American journal of physiology. Lung cellular and molecular physiology; Vol 311(6). 2016 Dec 01. Stone VMiller MRClift MJElder AMills NLMøller PSchins RPVogel UKreyling WGJensen KAKuhlbusch TASchwarze PEHoet PPietroiusti ADe Vizcaya-Ruiz ABaeza-Squiban ATran CLCassee FR Nanomaterials vs Ambient Ultrafine Particles: an Opportunity to Exchange Toxicology Knowledge.; Environmental health perspectives. 2016 Nov 04. Guttenberg MBezerra LNeu-Baker NMDel Pilar Sosa Idelchik MElder AOberdörster GBrenner SA Biodistribution of inhaled metal oxide nanoparticles mimicking occupational exposure: a preliminary investigation using enhanced darkfield microscopy.; Journal of biophotonics. 2016 Aug 16. Lerner CARutagarama PAhmad TSundar IKElder ARahman I Electronic cigarette aerosols and copper nanoparticles induce mitochondrial stress and promote DNA fragmentation in lung fibroblasts.; Biochemical and biophysical research communications. 2016 Jun 22. Lerner CASundar IKWatson RMElder AJones RDone DKurtzman ROssip DJRobinson RMcIntosh SRahman I Environmental health hazards of e-cigarettes and their components: Oxidants and copper in e-cigarette aerosols.; Environmental pollution (Barking, Essex : 1987); Vol 198. 2015 Mar. Gordon SCButala JHCarter JMElder AGordon TGray GSayre PGSchulte PATsai CSWest J Workshop report: strategies for setting occupational exposure limits for engineered nanomaterials.; Regulatory toxicology and pharmacology : RTP; Vol 68(3). 2014 Apr. Sotiriou GAWatson CMurdaugh KMDarrah THPyrgiotakis GElder ABrain JDDemokritou P Engineering safer-by-design, transparent, silica-coated ZnO nanorods with reduced DNA damage potential.; Environmental science. Nano; Vol 1(2). 2014 Apr. Baisch BLCorson NMWade-Mercer PGelein RKennell AJOberdörster GElder A Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation.; Particle and fibre toxicology; Vol 11. 2014. Mortensen LJJatana SGelein RDe Benedetto ADe Mesy Bentley KLBeck LAElder ADelouise LA Quantification of quantum dot murine skin penetration with UVR barrier impairment.; Nanotoxicology; Vol 7(8). 2013 Dec. Doudrick KCorson NOberdörster GElder ACHerckes PHalden RUWesterhoff P Extraction and quantification of carbon nanotubes in biological matrices with application to rat lung tissue.; ACS nano; Vol 7(10). 2013 Oct 22. Baer DREngelhard MHJohnson GELaskin JLai JMueller KMunusamy PThevuthasan SWang HWashton NElder ABaisch BLKarakoti AKuchibhatla SVMoon D Surface characterization of nanomaterials and nanoparticles: Important needs and challenging opportunities.; Journal of vacuum science & technology. A, Vacuum, surfaces, and films : an official journal of the American Vacuum Society; Vol 31(5). 2013 Sep. Bonner JCSilva RMTaylor AJBrown JMHilderbrand SCCastranova VPorter DElder AOberdörster GHarkema JRBramble LAKavanagh TJBotta DNel APinkerton KE Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium.; Environmental health perspectives; Vol 121(6). 2013 Jun. Xia THamilton RFBonner JCCrandall EDElder AFazlollahi FGirtsman TAKim KMitra SNtim SAOrr GTagmount MTaylor AJTelesca DTolic AVulpe CDWalker AJWang XWitzmann FAWu NXie YZink JINel AHolian A Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.; Environmental health perspectives; Vol 121(6). 2013 Jun. Block MLElder AAuten RLBilbo SDChen HChen JCCory-Slechta DACosta DDiaz-Sanchez DDorman DCGold DRGray KJeng HAKaufman JDKleinman MTKirshner ALawler CMiller DSNadadur SSRitz BSemmens EOTonelli LHVeronesi BWright ROWright RJ The outdoor air pollution and brain health workshop.; Neurotoxicology; Vol 33(5). 2012 Oct. Lucchini RGDorman DCElder AVeronesi B Neurological impacts from inhalation of pollutants and the nose-brain connection.; Neurotoxicology; Vol 33(4). 2012 Aug. Han XCorson NWade-Mercer PGelein RJiang JSahu MBiswas PFinkelstein JNElder AOberdörster G Assessing the relevance of in vitro studies in nanotoxicology by examining correlations between in vitro and in vivo data.; Toxicology; Vol 297(1-3). 2012 Jul 16. Shi MKwon HSPeng ZElder AYang H Effects of surface chemistry on the generation of reactive oxygen species by copper nanoparticles.; ACS nano; Vol 6(3). 2012 Mar 27. Han XGelein RCorson NWade-Mercer PJiang JBiswas PFinkelstein JNElder AOberdörster G Validation of an LDH assay for assessing nanoparticle toxicity.; Toxicology; Vol 287(1-3). 2011 Sep 5. Rivera Gil POberdörster GElder APuntes VParak WJ Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future.; ACS nano; Vol 4(10). 2010 Oct 26. Gillespie PAKang GSElder AGelein RChen LMoreira ALKoberstein JTchou-Wong KMGordon TChen LC Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: short and long-term studies in mice.; Nanotoxicology; Vol 4(1). 2010 Mar 1. Kim SCChen DRQi CGelein RMFinkelstein JNElder ABentley KOberdörster GPui DY A nanoparticle dispersion method for in vitro and in vivo nanotoxicity study.; Nanotoxicology; Vol 4(1). 2010 Mar. Rushton EKJiang JLeonard SSEberly SCastranova VBiswas PElder AHan XGelein RFinkelstein JOberdörster G Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics.; Journal of toxicology and environmental health. Part A; Vol 73(5). 2010. Kim SCChen DQi CGelein RMFinkelstein JNElder ABentley KOberdorster GPui D A nanoparticle dispersion method of in vitro and in vivo nanotoxicity study; Nanotoxicology; Vol 4(1), pp. 42-51. 2010 Jan 01. Gillespie PAKang GSElder AGelein RChen LMoreira ALKoberstein JTchou-Wang KMGordon TChen LC Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: short and long-term studies in mice; Nanotoxicology; Vol 4(1), pp. 106-19. 2010 Jan 01. Oberdörster GElder ARinderknecht A Nanoparticles and the brain: cause for concern?.; Journal of nanoscience and nanotechnology; Vol 9(8). 2009 Aug. Elder A Nanotoxicology: How do nanotubes suppress T cells?; Nature nanotechnology; Vol 4(7). 2009 Jul. Elder AVidyasagar SDeLouise L Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers.; Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology; Vol 1(4). 2009 Jul. Linkov ISteevens JAdlakha-Hutcheon GBennett EChappell MColvin VDavis JMDavis TElder AFoss Hansen SHakkinen PBHussain SMKarkan DKorenstein RLynch IMetcalfe CRamadan ABSatterstrom FK Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: summary of NATO Advanced Research Workshop.; Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology; Vol 11(3). 2009 Apr. Vanwinkle BAde Mesy Bentley KLMalecki JMGunter KKEvans IMElder AFinkelstein JNOberdörster GGunter TE Nanoparticle (NP) uptake by type I alveolar epithelial cells and their oxidant stress response.; Nanotoxicology; Vol 3(4). 2009 Jan 1. Jiang JOberdörster GElder AGelein RMercer PBiswas P Does Nanoparticle Activity Depend upon Size and Crystal Phase?; Nanotoxicology; Vol 2(1). 2008 Mar. Jiang JOberdorster GElder AGelein RMercer PBiswas P Does nanoparticles activity depend on size and crystal phase?; Nanotoxicology; Vol 2(1), pp. 33-42. 2008 Jan 01. Elder AYang HGwizada RTeng XThurston SHe HOberdörster G A Testing Strategy for Nanomaterials of Unknown Toxicity: An Example using Platinum Nanoparticles of Different Shapes.; Adv. Mater.. 2007 Jan 01. Wagner JGElder AGelein RCarter JMDriscoll KEOberdörster GHarkema JR Nasal Toxicity in Laboratory Rats After Subchronic Inhalation Exposure to Carbon Black Nanoparticles; Int'l. J. Nanotechnol.. 2007 Jan 01. Elder ACouderc JPGelein REberly SCox CXia XZareba WHopke PWatts WKittelson DFrampton MUtell MOberdörster G Effects of on-road highway aerosol exposures on autonomic responses in aged, spontaneously hypertensive rats.; Inhalation toxicology; Vol 19(1). 2007 Jan. Carter JMCorson NDriscoll KEElder AFinkelstein JNHarkema JNGelein RWade-Mercer PNguyen KOberdorster G A comparative dose-related response of several key pro- and antiinflammatory mediators in the lungs of rats, mice, and hamsters after subchronic inhalation of carbon black.; Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine; Vol 48(12). 2006 Dec.