URMC / Labs / Falsetta Lab / Publications Publications Falsetta MLMaddipati KRHonn KV Inflammation, lipids, and pain in vulvar disease.; Pharmacology & therapeutics; Vol 248, pp. 108467. 2023 Jun 05. Bekauri TFischer SHonn KVMaddipati KRLove TLittle CWood RWBonham ADLinder MAYule DIEmanuelle CFalsetta ML Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain.; Pain. 2023 Jan 26. Falsetta ML Editorial: Vulvodynia and beyond: innate immune sensing, microbes, inflammation, and chronic pain.; Frontiers in cellular and infection microbiology; Vol 13, pp. 1338659. 2023 Jan 08. Xiao JZeng YRustchenko EHuang XWu TTFalsetta ML Dual transcriptome of Streptococcus mutans and Candida albicans interplay in biofilms.; Journal of oral microbiology; Vol 15(1), pp. 2144047. 2022 Jan 09. Falsetta MLWood RWLinder MABonham ADHonn KVMaddipati KRPhipps RPHaidaris CGFoster DC Specialized pro-resolving mediators reduce pro-nociceptive inflammatory mediator production in models of localized provoked vulvodynia.; The journal of pain. 2021 Apr 01. Flores EMWoeller CFFalsetta MLSusiarjo MPhipps RP Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2018 Oct 30. Duffney PFFalsetta MLRackow ARThatcher THPhipps RPSime PJ Key roles for lipid mediators in the adaptive immune response.; The Journal of clinical investigation; Vol 128(7). 2018 Jul 02. Falsetta MLFoster DCWoeller CFPollock SJBonham ADPiekna-Przybylska DMaggirwar SBHaidaris CGPhipps RP Toll-Like Receptor Signaling Contributes to Proinflammatory Mediator Production in Localized Provoked Vulvodynia.; Journal of lower genital tract disease; Vol 22(1). 2018 Jan. Falsetta MLFoster DCWoeller CFPollock SJBonham ADHaidaris CGPhipps RP A role for bradykinin signaling in chronic vulvar pain.; The journal of pain : official journal of the American Pain Society. 2016 Aug 17. Falsetta MLFoster DCBonham ADPhipps RP A review of the available clinical therapies for vulvodynia management and new data implicating proinflammatory mediators in pain elicitation.; BJOG : an international journal of obstetrics and gynaecology. 2016 Jun 17. Falsetta MLFoster DCWoeller CFPollock SJBonham ADHaidaris CGStodgell CJPhipps RP Identification of novel mechanisms involved in generating localized vulvodynia pain.; American journal of obstetrics and gynecology; Vol 213(1). 2015 Jul. Foster DCFalsetta MLWoeller CFPollock SJSong KBonham AHaidaris CGStodgell CJMessing SPIadarola MPhipps RP Site-specific mesenchymal control of inflammatory pain to yeast challenge in vulvodynia-afflicted and pain-free women.; Pain; Vol 156(3). 2015 Mar. Falsetta MLKlein MIColonne PMScott-Anne KGregoire SPai CHGonzalez-Begne MWatson GKrysan DJBowen WHKoo H Symbiotic relationship between Streptococcus mutans and Candida albicans synergizes virulence of plaque biofilms in vivo.; Infection and immunity; Vol 82(5). 2014 May. Sommerfeld Ross STu MHFalsetta MLKetterer MRKiedrowski MRHorswill ARApicella MAReinhardt JMFiegel J Quantification of confocal images of biofilms grown on irregular surfaces.; Journal of microbiological methods; Vol 100. 2014 May. Nguyen PTFalsetta MLHwang GGonzalez-Begne MKoo H α-Mangostin disrupts the development of Streptococcus mutans biofilms and facilitates its mechanical removal.; PloS one; Vol 9(10). 2014. Koo HFalsetta MLKlein MI The exopolysaccharide matrix: a virulence determinant of cariogenic biofilm.; Journal of dental research; Vol 92(12). 2013 Dec. Bueno-Silva BKoo HFalsetta MLAlencar SMIkegaki MRosalen PL Effect of neovestitol-vestitol containing Brazilian red propolis on accumulation of biofilm in vitro and development of dental caries in vivo.; Biofouling; Vol 29(10). 2013. Falsetta MLKlein MILemos JASilva BBAgidi SScott-Anne KKKoo H Novel antibiofilm chemotherapy targets exopolysaccharide synthesis and stress tolerance in Streptococcus mutans to modulate virulence expression in vivo.; Antimicrobial agents and chemotherapy; Vol 56(12). 2012 Dec. Djoko KYFraniek JAEdwards JLFalsetta MLKidd SPPotter AJChen NHApicella MAJennings MPMcEwan AG Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress.; Infection and immunity; Vol 80(3). 2012 Mar. Phillips NJSteichen CTSchilling BPost DMNiles RKBair TBFalsetta MLApicella MAGibson BW Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outermembrane proteins.; PloS one; Vol 7(6). 2012. Xiao JKlein MIFalsetta MLLu BDelahunty CMYates JRHeydorn AKoo H The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm.; PLoS pathogens; Vol 8(4). 2012. Jeon JGPandit SXiao JGregoire SFalsetta MLKlein MIKoo H Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms.; International journal of oral science; Vol 3(2). 2011 Apr. Jeon JGRosalen PLFalsetta MLKoo H Natural products in caries research: current (limited) knowledge, challenges and future perspective.; Caries research; Vol 45(3). 2011. Falsetta MLSteichen CTMcEwan AGCho CKetterer MShao JHunt JJennings MPApicella MA The Composition and Metabolic Phenotype of Neisseria gonorrhoeae Biofilms.; Frontiers in microbiology; Vol 2. 2011. Falsetta MLMcEwan AGJennings MPApicella MA Anaerobic metabolism occurs in the substratum of gonococcal biofilms and may be sustained in part by nitric oxide.; Infection and immunity; Vol 78(5). 2010 May. Falsetta MLBair TBKu SCVanden Hoven RNSteichen CTMcEwan AGJennings MPApicella MA Transcriptional profiling identifies the metabolic phenotype of gonococcal biofilms.; Infection and immunity; Vol 77(9). 2009 Sep. Potter AJKidd SPEdwards JLFalsetta MLApicella MAJennings MPMcEwan AG Esterase D is essential for protection of Neisseria gonorrhoeae against nitrosative stress and for bacterial growth during interaction with cervical epithelial cells.; The Journal of infectious diseases; Vol 200(2). 2009 Jul 15. Srikhanta YNDowideit SJEdwards JLFalsetta MLWu HJHarrison OBFox KLSeib KLMaguire TLWang AHMaiden MCGrimmond SMApicella MAJennings MP Phasevarions mediate random switching of gene expression in pathogenic Neisseria.; PLoS pathogens; Vol 5(4). 2009 Apr. Potter AJKidd SPEdwards JLFalsetta MLApicella MAJennings MPMcEwan AG Thioredoxin reductase is essential for protection of Neisseria gonorrhoeae against killing by nitric oxide and for bacterial growth during interaction with cervical epithelial cells.; The Journal of infectious diseases; Vol 199(2). 2009 Jan 15. Lim KHJones CEvanden Hoven RNEdwards JLFalsetta MLApicella MAJennings MPMcEwan AG Metal binding specificity of the MntABC permease of Neisseria gonorrhoeae and its influence on bacterial growth and interaction with cervical epithelial cells.; Infection and immunity; Vol 76(8). 2008 Aug. Seib KLWu HJSrikhanta YNEdwards JLFalsetta MLHamilton AJMaguire TLGrimmond SMApicella MAMcEwan AGJennings MP Characterization of the OxyR regulon of Neisseria gonorrhoeae.; Molecular microbiology; Vol 63(1). 2007 Jan.