Recent Publications

• 1. Lee C
  2. Shokrian M
  3. Henry KS
  4. Carney LH
  5. Holt JC
  6. Nam JH
  Outer hair cells stir cochlear fluids.; bioRxiv : the preprint server for biology. 2024 Aug 09.
• 1. Heffer A
  2. Lee C
  3. Holt JC
  4. Kiernan AE
  Notch1 is required to maintain supporting cell identity and vestibular function during maturation of the mammalian balance organs.; bioRxiv : the preprint server for biology. 2024 Jun 21.
• 1. Poppi LA
  2. Bigland MJ
  3. Cresswell ET
  4. Tabatabaee H
  5. Lorincz D
  6. Drury HR
  7. Callister RJ
  8. Holt JC
  9. Lim R
  10. Brichta AM
  11. Smith DW
  Molecular and functional changes to postsynaptic cholinergic signaling in the vestibular sensory organs of aging C57BL/6 mice.; The journals of gerontology. Series A, Biological sciences and medical sciences. 2023 Feb 25.
• 1. Schneider GT
  2. Lee C
  3. Sinha AK
  4. Jordan PM
  5. Holt JC
  The mammalian efferent vestibular system utilizes cholinergic mechanisms to excite primary vestibular afferents.; Scientific reports; Vol 11(1). 2021 Jan 13.
• 1. Lee C
  2. Sinha AK
  3. Henry K
  4. Walbaum AW
  5. Crooks PA
  6. Holt JC
  Characterizing the Access of Cholinergic Antagonists to Efferent Synapses in the Inner Ear.; Frontiers in neuroscience; Vol 15. 2021.
• 1. Lorincz D
  2. Poppi LA
  3. Holt JC
  4. Drury HR
  5. Lim R
  6. Brichta AM
  The Long and Winding Road-Vestibular Efferent Anatomy in Mice.; Frontiers in neural circuits; Vol 15. 2021.
• 1. Jabeen T
  2. Holt JC
  3. Becker JR
  4. Nam JH
  Interactions between Passive and Active Vibrations in the Organ of Corti In Vitro.; Biophysical journal. 2020 Jun 17.
• 1. Poppi LA
  2. Holt JC
  3. Lim R
  4. Brichta AM
  A review of efferent cholinergic synaptic transmission in the vestibular periphery and its functional implications.; Journal of neurophysiology; Vol 123(2). 2020 Feb 01.
• 1. Jones SM
  2. Vijayakumar S
  3. Dow SA
  4. Holt JC
  5. Jordan PM
  6. Luebke AE
  Loss of α-Calcitonin Gene-Related Peptide (αCGRP) Reduces Otolith Activation Timing Dynamics and Impairs Balance.; Frontiers in molecular neuroscience; Vol 11. 2018.
• 1. Poppi LA
  2. Tabatabaee H
  3. Drury HR
  4. Jobling P
  5. Callister RJ
  6. Migliaccio AA
  7. Jordan PM
  8. Holt JC
  9. Rabbitt RD
  10. Lim R
  11. Brichta AM
  ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells.; Journal of neurophysiology. 2017 Oct 04.
• 1. Lee C
  2. Holt JC
  3. Jones TA
  The effect of M-current modulation on mammalian vestibular responses to transient head motion.; Journal of neurophysiology. 2017 Aug 30.
• 1. Holt JC
  2. Jordan PM
  3. Lysakowski A
  4. Shah A
  5. Barsz K
  6. Contini D
  Muscarinic Acetylcholine Receptors and M-Currents Underlie Efferent-Mediated Slow Excitation in Calyx-Bearing Vestibular Afferents.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 37(7). 2017 Feb 15.
• 1. Parks XX
  2. Contini D
  3. Jordan PM
  4. Holt JC
  Confirming a Role for α9nAChRs and SK Potassium Channels in Type II Hair Cells of the Turtle Posterior Crista.; Frontiers in cellular neuroscience; Vol 11. 2017.
• 1. Dickerson IM
  2. Bussey-Gaborski R
  3. Holt JC
  4. Jordan PM
  5. Luebke AE
  Maturation of suprathreshold auditory nerve activity involves cochlear CGRP-receptor complex formation.; Physiological reports; Vol 4(14). 2016 Jul.
• 1. Jordan PM
  2. Fettis M
  3. Holt JC
  Efferent innervation of turtle semicircular canal cristae: comparisons with bird and mouse.; The Journal of comparative neurology; Vol 523(8). 2015 Jun 1.
• 1. Holt JC
  2. Kewin K
  3. Jordan PM
  4. Cameron P
  5. Klapczynski M
  6. McIntosh JM
  7. Crooks PA
  8. Dwoskin LP
  9. Lysakowski A
  Pharmacologically distinct nicotinic acetylcholine receptors drive efferent-mediated excitation in calyx-bearing vestibular afferents.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 35(8). 2015 Feb 25.
• 1. Luebke AE
  2. Holt JC
  3. Jordan PM
  4. Wong YS
  5. Caldwell JS
  6. Cullen KE
  Loss of α-Calcitonin Gene-Related Peptide (αCGRP) Reduces the Efficacy of the Vestibulo-ocular Reflex (VOR).; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 34(31). 2014 Jul 30.
• 1. Jordan PM
  2. Parks XX
  3. Contini D
  4. Holt JC
  A review of synaptic mechanisms of vestibular efferent signaling in turtles: extrapolation to efferent actions in mammals.; Journal of vestibular research : equilibrium & orientation; Vol 23(3). 2013.
• 1. Holt JC
  2. Chatlani S
  3. Lysakowski A
  4. Goldberg JM
  Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista.; Journal of neurophysiology; Vol 98(3). 2007 Sep.
• 1. Holt JC
  2. Lysakowski A
  3. Goldberg JM
  Mechanisms of efferent-mediated responses in the turtle posterior crista.; The Journal of neuroscience : the official journal of the Society for Neuroscience; Vol 26(51). 2006 Dec 20.
• 1. Holt JC
  2. Xue JT
  3. Brichta AM
  4. Goldberg JM
  Transmission between type II hair cells and bouton afferents in the turtle posterior crista.; Journal of neurophysiology; Vol 95(1). 2006 Jan.
• 1. Holt JC
  2. Lioudyno M
  3. Guth PS
  A pharmacologically distinct nicotinic ACh receptor is found in a subset of frog semicircular canal hair cells.; Journal of neurophysiology; Vol 90(3). 2003 Sep.
• 1. Lioudyno MI
  2. Verbitsky M
  3. Glowatzki E
  4. Holt JC
  5. Boulter J
  6. Zadina JE
  7. Elgoyhen AB
  8. Guth PS
  The alpha9/alpha10-containing nicotinic ACh receptor is directly modulated by opioid peptides, endomorphin-1, and dynorphin B, proposed efferent cotransmitters in the inner ear.; Molecular and cellular neurosciences; Vol 20(4). 2002 Aug.
• 1. Holt JC
  2. Lioudyno M
  3. Athas G
  4. Garcia MM
  5. Perin P
  6. Guth PS
  The effect of proteolytic enzymes on the alpha9-nicotinic receptor-mediated response in isolated frog vestibular hair cells.; Hearing research; Vol 152(1-2). 2001 Feb.
• 1. Lioudyno MI
  2. Verbitsky M
  3. Holt JC
  4. Elgoyhen AB
  5. Guth PS
  Morphine inhibits an alpha9-acetylcholine nicotinic receptor-mediated response by a mechanism which does not involve opioid receptors.; Hearing research; Vol 149(1-2). 2000 Nov.
• 1. Holt JC
  2. Pantoja AM
  3. Athas GB
  4. Guth PS
  A role for chloride in the hyperpolarizing effect of acetylcholine in isolated frog vestibular hair cells.; Hearing research; Vol 146(1-2). 2000 Aug.
• 1. Guth PS
  2. Holt JC
  3. Perin P
  4. Athas G
  5. Garcia M
  6. Puri A
  7. Zucca G
  8. Botta L
  9. Valli P
  The metabotropic glutamate receptors of the vestibular organs.; Hearing research; Vol 125(1-2). 1998 Nov.
• 1. Norris CH
  2. Miller AJ
  3. Perin P
  4. Holt JC
  5. Guth PS
  Mechanisms and effects of transepithelial polarization in the isolated semicircular canal.; Hearing research; Vol 123(1-2). 1998 Sep.
• 1. Pantoja AM
  2. Holt JC
  3. Guth PS
  A role for chloride in the suppressive effect of acetylcholine on afferent vestibular activity.; Hearing research; Vol 112(1-2). 1997 Oct.
• 1. Michel RE
  2. Holt JC
  3. Domer FR
  Ketorolac causes the release of methionine-enkephalin in rats.; Research communications in molecular pathology and pharmacology; Vol 91(2). 1996 Feb.