URMC / Labs / Korman Lab / Publications Publications Khan LDerksen TRedmond DStorek JDurand CGniadecki RKorman BCohen Tervaert JWD'Aubeterre AOsman MSWillis LM The cancer-associated glycan polysialic acid is dysregulated in systemic sclerosis and is associated with fibrosis.; Journal of autoimmunity; Vol 140, pp. 103110. 2023 Sep 22. Kenney HMRangel-Moreno JPeng YChen KLBruno JEmbong APritchett EFox JIBecerril-Villanueva EGamboa-Domínguez AQuataert SMuthukrishnan GWood RWKorman BDAnolik JHXing LRitchlin CTSchwarz EMWu CL Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.; Frontiers in immunology; Vol 14, pp. 1237498. 2023 Aug 25. Korman BDLachant DJCastelino FV Pulmonary Hypertension: How to Best Treat the Different Scleroderma Phenotypes?; Rheumatic diseases clinics of North America; Vol 49(2), pp. 345-357. 2023 May. Murphy SLChen YTLee YCCarns MAren KKorman BHinchcliff MVarga J Differences in symptom experience among patients with systemic sclerosis: a cluster analytic approach to identifying subgroups.; Rheumatology (Oxford, England); Vol 62(SI), pp. SI64-SI73. 2023 Feb 06. Kenney HMWood RWRamirez GBell RDChen KLSchnur LRahimi HKorman BDXing LRitchlin CTSchwarz EMCole CL Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice.; Arthritis research & therapy; Vol 25(1), pp. 17. 2023 Feb 02. Yang MMBalmert LCMarangoni RGCarns MHinchcliff MKorman BDVarga J Circulating CTRP9 Is Associated With Severity of Systemic Sclerosis-Associated Interstitial Lung Disease.; Arthritis care & research; Vol 75(1), pp. 152-157. 2022 Aug 24. Kruzer KGoncalves Marangoni RHeckler IElhage AVarga JHinchcliff MCarns MAren KWielgosz ANuzzo MVenkataraman IKorman B Clinical and Autoantibody Associations in Antinuclear Antibody-Positive Systemic Sclerosis Lacking Prototypic Autoantibodies.; Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases; Vol 29(1), pp. 47-51. 2022 Jun 28. Roberson EDOCarns MCao LAren KGoldberg IAMorales-Heil DJKorman BDAtkinson JPVarga J Alterations of the Primary Cilia Gene SPAG17 and SOX9 Locus Noncoding RNAs Identified by RNA-Sequencing Analysis in Patients With Systemic Sclerosis.; Arthritis & rheumatology (Hoboken, N.J.); Vol 75(1), pp. 108-119. 2022 Jan 29. Marangoni RGDatta PPaine ADuemmel SNuzzo MSherwood LVarga JRitchlin CKorman BD Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma.; JCI insight; Vol 7(19). 2022 Jan 10. Marangoni RGKorman BDParra ERVelosa APPBarbeiro HVMartins VDos Santos ABGSoriano FTeodoro WRSilva PLTourtellotte WCapelozzi VLVarga JYoshinari NH Pathological pulmonary vascular remodeling is induced by type V collagen in a model of scleroderma.; Pathology, research and practice; Vol 220. 2021 Feb 19. De Pieri AKorman BDJüngel AWuertz-Kozak K Engineering Advanced In Vitro Models of Systemic Sclerosis for Drug Discovery and Development.; Advanced biology; Vol 5(4), pp. e2000168. 2021 Feb 15. De Pieri AKorman BJüngel AWuertz-Kozak K Engineering Advanced In Vitro Models of Systemic Sclerosis for Drug Discovery and Development.; Advanced Biosystems.. 2021 Jan 01. Shi BWang WKorman BKai LWang QWei JBale SMarangoni RGBhattacharyya SMiller SXu DAkbarpour MCheresh PProccissi DGursel DEspindola-Netto JMChini CCSde Oliveira GCGudjonsson JEChini ENVarga J Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis.; iScience; Vol 24(1). 2021 Jan 22. Marangoni RGKorman BVarga J Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs.; Current rheumatology reports; Vol 22(11). 2020 Sep 25. Bell RDWhite RJGarcia-Hernandez MLWu ERahimi HMarangoni RGSlattery PDuemmel SNuzzo MHuertas NYee MO'Reilly MAMorrell CRitchlin CTSchwarz EMKorman BD TNF Induces Obliterative Pulmonary Vascular Disease in a Novel Model of Connective Tissue Disease Associated Pulmonary Arterial Hypertension (CTD-PAH).; Arthritis & rheumatology (Hoboken, N.J.). 2020 May 10. Lemay MKorman BHammert WWhite RJLachant D Combination treprostinil with sympathectomy and vascular reconstruction to treat recurrent digital ulcer disease.; Clinical and experimental rheumatology. 2020 Apr 15. Gourh PSafran SAAlexander TBoyden SEMorgan NDShah AAMayes MDDoumatey ABentley ARShriner DDomsic RTMedsger TARamos PSSilver RMSteen VDVarga JHsu VSaketkoo LASchiopu EKhanna DGordon JKKron BCriswell LAGladue HDerk CTBernstein EJBridges SLShanmugam VKKolstad KDChung LKafaja SJan RTrojanowski MGoldberg AKorman BDSteinbach PJChandrasekharappa SCMullikin JCAdeyemo ARotimi CWigley FMKastner DLBoin FRemmers EF HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry.; Proceedings of the National Academy of Sciences of the United States of America; Vol 117(1). 2020 Jan 07. Mitchell DCAgnihothri RScott GAKorman BRichardson CT A case of concurrent systemic sclerosis and scleredema.; JAAD case reports; Vol 5(11). 2019 Nov. Korman B Evolving insights into the cellular and molecular pathogenesis of fibrosis in systemic sclerosis.; Translational research : the journal of laboratory and clinical medicine; Vol 209. 2019 Jul. Gourh PRemmers EFBoyden SEAlexander TMorgan NDShah AAMayes MDDoumatey ABentley ARShriner DDomsic RTMedsger TASteen VDRamos PSSilver RMKorman BVarga JSchiopu EKhanna DHsu VGordon JKSaketkoo LAGladue HKron BCriswell LADerk CTBridges SLShanmugam VKKolstad KDChung LJan RBernstein EJGoldberg ATrojanowski MKafaja SMaksimowicz-McKinnon KMMullikin JCAdeyemo ARotimi CBoin FKastner DLWigley FM Brief Report: Whole-Exome Sequencing to Identify Rare Variants and Gene Networks That Increase Susceptibility to Scleroderma in African Americans.; Arthritis & rheumatology (Hoboken, N.J.); Vol 70(10). 2018 Oct. Korman BMarangoni RGLord GOlefsky JTourtellotte WVarga J Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis.; Arthritis research & therapy; Vol 20(1). 2018 Jul 11. Korman BAlejo RSudhakar DHinchcliff MAgrawal RVarga JMarangoni RG The novel adipokine C1q-TNF related protein 9 (CTRP9) is elevated in systemic sclerosis-associated interstitial lung disease.; Clinical and experimental rheumatology; Vol 36 Suppl 113(4). 2018 Jul. Marangoni RGMasui YFang FKorman BLord GLee JLakota KWei JScherer PEOtvos LYamauchi TKubota NKadowaki TAsano YSato STourtellotte WGVarga J Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.; Scientific reports; Vol 7(1). 2017 Jun 30. Wei JZhu HLord GBhattachayya MJones BMAllaway GBiswal SSKorman BMarangoni RGTourtellotte WGVarga J Nrf2 exerts cell-autonomous antifibrotic effects: compromised function in systemic sclerosis and therapeutic rescue with a novel heterocyclic chalcone derivative.; Translational research : the journal of laboratory and clinical medicine; Vol 183. 2017 May. Korman BDMarangoni RGHinchcliff MShah SJCarns MHoffmann ARamsey-Goldman RVarga J Brief Report: Association of Elevated Adipsin Levels With Pulmonary Arterial Hypertension in Systemic Sclerosis.; Arthritis & rheumatology (Hoboken, N.J.); Vol 69(10). 2017 Jan. Korman BWei JLaumann AFerguson PVarga J Mutation in LEMD3 (Man1) Associated with Osteopoikilosis and Late-Onset Generalized Morphea: A New Buschke-Ollendorf Syndrome Variant.; Case reports in dermatological medicine; Vol 2016. 2016. Marangoni RGKorman BDAllanore YDieude PArmstrong LLRzhetskaya MHinchcliff MCarns MPodlusky SShah SJRuiz BHachulla ETiev KCracowski JLVarga JHayes MG A candidate gene study reveals association between a variant of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) gene and systemic sclerosis.; Arthritis research & therapy; Vol 17. 2015 May 19. Marangoni RGKorman BDWei JWood TAGraham LVWhitfield MLScherer PETourtellotte WGVarga J Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors.; Arthritis & rheumatology (Hoboken, N.J.); Vol 67(4). 2015 Apr. Korman BDCriswell LA Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.; Current rheumatology reports; Vol 17(3). 2015 Mar. Korman BDHuang CCSkamra CWu PKoessler RYao DHuang QQPearce WSutton-Tyrrell KKondos GEdmundowicz DPope RRamsey-Goldman R Inflammatory expression profiles in monocyte-to-macrophage differentiation in patients with systemic lupus erythematosus and relationship with atherosclerosis.; Arthritis research & therapy; Vol 16(4). 2014 Jul 10. Remmers EFCosan FKirino YOmbrello MJAbaci NSatorius CLe JMYang BKorman BDCakiris AAglar OEmrence ZAzakli HUstek DTugal-Tutkun IAkman-Demir GChen WAmos CIDizon MBKose AAAzizlerli GErer BBrand OJKaklamani VGKaklamanis PBen-Chetrit EStanford MFortune FGhabra MOllier WECho YHBang DO'Shea JWallace GRGadina MKastner DLGül A Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.; Nature genetics; Vol 42(8). 2010 Aug. Korman BDTyler KLKorman NJ Progressive multifocal leukoencephalopathy, efalizumab, and immunosuppression: a cautionary tale for dermatologists.; Archives of dermatology; Vol 145(8). 2009 Aug. Aksentijevich IMasters SLFerguson PJDancey PFrenkel Jvan Royen-Kerkhoff ALaxer RTedgård UCowen EWPham THBooty MEstes JDSandler NGPlass NStone DLTurner MLHill SButman JASchneider RBabyn PEl-Shanti HIPope EBarron KBing XLaurence ALee CCChapelle DClarke GIOhson KNicholson MGadina MYang BKorman BDGregersen PKvan Hagen PMHak AEHuizing MRahman PDouek DCRemmers EFKastner DLGoldbach-Mansky R An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist.; The New England journal of medicine; Vol 360(23). 2009 Jun 04. Lee HSKorman BDLe JMKastner DLRemmers EFGregersen PKBae SC Genetic risk factors for rheumatoid arthritis differ in Caucasian and Korean populations.; Arthritis and rheumatism; Vol 60(2). 2009 Feb. Korman BDSeldin MFTaylor KELe JMLee ATPlenge RMAmos CICriswell LAGregersen PKKastner DLRemmers EF The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series.; Arthritis and rheumatism; Vol 60(1). 2009 Jan. Parker SRDyson SBrisman SPennie MSwerlick RAKhan RManos SKorman BDXia ZKorman NJ Mortality of bullous pemphigoid: an evaluation of 223 patients and comparison with the mortality in the general population in the United States.; Journal of the American Academy of Dermatology; Vol 59(4). 2008 Oct. Raychaudhuri SRemmers EFLee ATHackett RGuiducci CBurtt NPGianniny LKorman BDPadyukov LKurreeman FAChang MCatanese JJDing BWong Svan der Helm-van Mil AHNeale BMCoblyn JCui JTak PPWolbink GJCrusius JBvan der Horst-Bruinsma IECriswell LAAmos CISeldin MFKastner DLArdlie KGAlfredsson LCostenbader KHAltshuler DHuizinga TWShadick NAWeinblatt MEde Vries NWorthington JSeielstad MToes REKarlson EWBegovich ABKlareskog LGregersen PKDaly MJPlenge RM Common variants at CD40 and other loci confer risk of rheumatoid arthritis.; Nature genetics; Vol 40(10). 2008 Oct. Korman BDKastner DLGregersen PKRemmers EF STAT4: genetics, mechanisms, and implications for autoimmunity.; Current allergy and asthma reports; Vol 8(5). 2008 Sep. Korman BDAlba MILe JMAlevizos ISmith JANikolov NPKastner DLRemmers EFIllei GG Variant form of STAT4 is associated with primary Sjögren's syndrome.; Genes and immunity; Vol 9(3). 2008 Apr. Robinson MRKorman BDKorman NJ Combination immunosuppressive therapies: the promise and the peril.; Archives of dermatology; Vol 143(8). 2007 Aug.