Leckenby Lab
Welcome to the Leckenby Lab
The Leckenby lab primarily focuses on enhancing the regeneration and preventing the degeneration of the peripheral nervous system. Our research aims to:
- Understand the mechanisms that can be manipulated to prevent scar formation in the injured peripheral nerve to improve outcomes following surgical repair.
- Improving the quality of lives of cancer survivors through the prevention and/or reversal of the symptoms of peripheral neuropathy induced by cancer treatment.
- Improving the outcomes of surgery to treat facial paralysis by developing standardized outcomes reporting.
Our lab takes a collaborative approach to research to maximize the impact of our work. The ultimate goal is to improve the patients we treat by taking the lessons learned from the bench to the bedside.
Jonathan I. Leckenby, M.B.B.S., Ph.D.
Principal Investigator
Projects
- The use of diffusion magnetic resonance imaging to characterize the intra-cranial path of the facial nerve
- Developing an Automated Facial Symmetry Index (AFSI)
- QoL and surgical outcomes of vascularized composite allotransplantation
- Prevention and treatment of chemotherapy induced peripheral neuropathy
- Application of serial section microscopy to evaluate small tissue volumes in disease
Publications
View All Publications- Influencing factors and repair advancements in rodent models of peripheral nerve regeneration.; Regenerative medicine. 2024 Oct 29.
- A Systematic Review of the Reported Complications Related to Facial and Upper Extremity Vascularized Composite Allotransplantation.; The Journal of surgical research; Vol 281, pp. 164-175. 2022 Sep 23.
- Transcutaneous sentinel lymph node detection in cutaneous melanoma with indocyanine green and near-infrared fluorescence: A diagnostic sensitivity study.; Medicine; Vol 101(36), pp. e30424. 2022 Sep 09.
- 20 Years of Abdominal Wall Allotransplantation - A Systematic Review of the Short and Long-Term Outcomes with a View to Future Modifications.; Plastic and reconstructive surgery. 2022 Sep 01.
- Axonal Regeneration Through Autologous Grafts: Does the Axonal Load Influence Regeneration?; The Journal of surgical research; Vol 280, pp. 379-388. 2022 Aug 26.
- Free functional platysma transfer for restoration of spontaneous eye closure in facial paralysis: an analysis of anatomy, imaging, and clinical outcomes.; Plastic and reconstructive surgery. 2022 Jan 20.
- Evaluation of peripheral nerve regeneration in Murphy Roths Large mouse strain following transection injury.; Regenerative medicine. 2022 Jan 18.
Contact Us
Leckenby Lab
601 Elmwood Avenue
Rochester, NY 14627