Lerner Lab
Modeling the Biomechanics of the Knee
Finite element model of the knee meniscus.
The emphasis in our laboratory is on the use of computational modeling to study biomechanics in personalized treatment planning. Our interests include studying the role of gender, obesity, ethnicity, activities and meniscal injuries in the development of knee osteoarthritis. Using models based on medical imaging techniques such as micro-computed tomography and magnetic resonance imaging, our goal is to better understand the distribution of forces in the knee joint and how these may be related to risks for the onset or progression of osteoarthritis. In similar studies, we also are investigating the cornea and methods to identify individual material characteristics that may influence treatment options. We use statistical methods to expand experimental studies from their use as validation to also allow for robust predictions of anticipated performance.
Amy Lerner, Ph.D.
Principal Investigator
Projects
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Publications
View All Publications- Individualized Characterization of the Distribution of Collagen Fibril Dispersion Using Optical Aberrations of the Cornea for Biomechanical Models.; Investigative ophthalmology & visual science; Vol 61(10). 2020 Aug 03.
- Core Competencies for Undergraduates in Bioengineering and Biomedical Engineering: Findings, Consequences, and Recommendations.; Annals of biomedical engineering; Vol 48(3). 2020 Mar.
- Controlled elevation of intraocular pressure and its impact on ocular aberrations in healthy eyes.; Experimental eye research; Vol 171. 2018 Mar 02.
- Sensitivity of corneal biomechanical and optical behavior to material parameters using design of experiments method.; Computer methods in biomechanics and biomedical engineering; Vol 21(3). 2018 Feb.
- Reducing uncertainty when using knee-specific finite element models by assessing the effect of input parameters.; Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2017 Jan 06.
- Computer Modeling Analysis of the Talar Dome as a Graft for the Humeral Head.; Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 2016 May 11.
- MRI-based analysis of patellofemoral cartilage contact, thickness, and alignment in extension, and during moderate and deep flexion.; The Knee; Vol 22(5). 2015 Oct.
Contact Us
Lerner Lab
Goergen Hall 307
Rochester, NY 14627
(585) 276-1999