Skip to main content
menu

Glutamate Receptors

MacLean Lab

Welcome to the MacLean Lab

We study how the structure of neurotransmitter-gated ion channels produces their unique biophysical and functional properties and also how these properties enable the receptors to fulfill specific roles in the brain. Our focus is on two families of ion channels: ionotropic Glutamate Receptors (iGluRs) and Acid Sensing Ion Channels (ASICs). To better understand these channels we combine patch clamp electrophysiology, kinetic and molecular modeling, fluorescence spectroscopy, unnatural amino acid incorporation and basic molecular biochemical techniques.

widget-666aa83f-6e6

David M. MacLean, Ph.D.

David M. MacLean, Ph.D.
Principal Investigator

Publications

widget-930121a3-a14

View All Publications

widget-c7200abd-52b

News

widget-ab2bcdce-87c

Affiliations

February 25, 2021
Matthew Rook Wins Poster Award at 2021 Biophysical Society Meeting

June 1, 2020
Matthew Rook awarded a Joan Wright Goodman Dissertation Fellowship

August 9, 2017
Dr. MacLean Attends Yale Retreat

June 3, 2017
Lyndee joins the lab

View All News

Contact Us

  MacLean Lab
601 Elmwood Ave
Rochester, NY 14642

 (585) 276-3032

  (585) 275-6007