The Science of Neuro-Glia Interaction
Welcome to the Science of Neuro-Glia Interaction Lab
My research program focuses on neuroglia interactions. Specifically, my lab studies how neuromodulators mediate the unique interactions between neurons, astrocytes, and microglia in healthy brains and how disruptions in neuronal-glial crosstalk contribute to ADHD, epilepsy, and insulin resistance. My research program is supported by the NIH, NSF, and DOD.
Lab Members
Nathan A. Smith, M.S., Ph.D.
Principal Investigator
Projects
Astrocytes modulate synaptic plasticity via Norepinephrine
NCS-FR: Protecting the Aging Brain: Self-Organizing Networks and Multi-Scale Dynamics Under Energy Constraints
Role of astrocytes in Ca2+-dependent microglia modulation of synaptic plasticity
Identification of biomarkers for biochemical pathophysiological and neurological effects of high ammonia
Publications
View All Publications- Anti-seizure effects of norepinephrine-induced free fatty acid release.; Cell metabolism. 2024 Oct 29.
- Ethnicity-related differences in mitochondrial regulation by insulin stimulation in diabetes.; Journal of cellular physiology; Vol 239(8), pp. e31317. 2024 May 22.
- D-ꞵ-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.; PNAS nexus; Vol 3(5), pp. pgae196. 2024 May 16.
- D-β-hydroxybutyrate stabilizes hippocampal CA3-CA1 circuit during acute insulin resistance.; bioRxiv : the preprint server for biology. 2024 May 12.
Contact Us
Nathan Smith Lab
The Science of Neuro-Glia Interaction