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URMC / Labs / O'Connell Lab / Lab Members

Lab Members

Principal Investigator

Mitchell O'Connell
Research Interest: Biochemical mechanisms of RNA-mediated gene regulation; RNA-targeting CRISPR tool development

Faculty

Bogdan Polevoda
Bogdan Polevoda, Ph.D.
Research Assistant Professor
MC
Phone: (585) 276-4107
Email Bogdan
Research Interest: The two cotranslational processes, cleavage of N-terminal methionine and N-terminal acetylation (N- acetylation).

Graduate Students

Brandon Davis
Research Interest:

 Picking up the Pieces: The Fragmented Process of Cas13 Mediated RNA Cleavage in Human Cells

Seth Jones
Research Interest:

Structural Studies of Cas13b Accessory Protein Csx27

Mert Koka
Research Interest:

Pulling the plug on bacteriophage infection: investigating the molecular mechanism of activation of CRISPR-Csx28

Julia Nicosia
Research Interest:

The role of the Type VI CRISPR-Cas accessory protein Csx27 in CRISPR-Cas13 mediated anti-viral immunity

Brandon Park
Research Interest:

Nucleic Acid Biology, Epigenetics, and Development. My project is focused on the role of H2A.Z in epigenetic inheritance.

James Shaul
Research Interest:

Type VI CRISPR and associated bacterial anti-phage defense systems