URMC / Labs / Pavelka Lab / Publications Publications Miller NJDimitrakopoulou DBaglia LAPavelka MSRobert J Exploring the Role of a Putative Secondary Metabolite Biosynthesis Pathway in Mycobacterium abscessus Pathogenesis Using a Xenopus laevis Tadpole Model.; Microorganisms; Vol 12(6). 2024 May 31. Chan HPavelka MSBaran TM Methylene blue photodynamic therapy of bacterial species found in human abscesses: Planktonic, biofilm, and 3D silicone models.; Proceedings of SPIE--the International Society for Optical Engineering; Vol 12358. 2023 Mar 14. Francis ZKSanders ANCrick DCMahapatra SIslam MNPavelka MS LdtC Is a Key l,d-Transpeptidase for Peptidoglycan Assembly in Mycobacterium smegmatis.; Journal of bacteriology. 2022 Jan 21. Paiola MDimitrakopoulou DPavelka MSRobert J Amphibians as a model to study the role of immune cell heterogeneity in host and mycobacterial interactions.; Developmental and comparative immunology; Vol 139, pp. 104594. 2022 Jan 18. Lopez AShoen CCynamon MDimitrakopoulou DPaiola MPavelka MSRobert J Developing Tadpole Xenopus laevis as a Comparative Animal Model to Study Mycobacterium abscessus Pathogenicity.; International journal of molecular sciences; Vol 22(2). 2021 Jan 15. Pidgeon SEApostolos AJNelson JMShaku MRimal BIslam MNCrick DCKim SJPavelka MSKana BDPires MM L,D-Transpeptidase Specific Probe Reveals Spatial Activity of Peptidoglycan Cross-Linking.; ACS chemical biology; Vol 14(10). 2019 Oct 18. Rhoo KHEdholm ESForzán MJKhan AWaddle AWPavelka MSRobert J Distinct Host-Mycobacterial Pathogen Interactions between Resistant Adult and Tolerant Tadpole Life Stages of Xenopus laevis.; Journal of immunology (Baltimore, Md. : 1950). 2019 Oct 07. Pavelka MS Snappy cell division in Actinobacteria.; Nature chemical biology; Vol 15(3). 2019 Mar. Wlodarchak NTeachout NBeczkiewicz JProcknow RSchaenzer AJSatyshur KPavelka MZuercher WDrewry DSauer JDStriker R In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with β-Lactams To Inhibit Mycobacterial Growth.; Molecular pharmaceutics. 2018 Oct 18. Edholm ESBanach MHyoe Rhoo KPavelka MSRobert J Distinct MHC class I-like interacting invariant T cell lineage at the forefront of mycobacterial immunity uncovered inXenopus.; Proceedings of the National Academy of Sciences of the United States of America. 2018 Apr 02. Gregoire SAByam JPavelka MS galK-based suicide vector mediated allelic exchange in Mycobacterium abscessus.; Microbiology (Reading, England). 2017 Sep 21. Martinelli DJPavelka MS The RipA and RipB Peptidoglycan Endopeptidases Are Individually Nonessential to Mycobacterium smegmatis.; Journal of bacteriology; Vol 198(9). 2016 May 1. Pavelka MS One of these is not like the others.; Trends in microbiology; Vol 23(11). 2015 Nov. Boule LAWinans BLambert KVorderstrasse BATopham DJPavelka MSLawrence BP Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.; American journal of physiology. Lung cellular and molecular physiology; Vol 309(3). 2015 Aug 1. LoVullo EDWright LFIsabella VHuntley JFPavelka MS Revisiting the Gram-negative lipoprotein paradigm.; Journal of bacteriology; Vol 197(10). 2015 May. Jin GPavelka MSButler JS Structure-function analysis of VapB4 antitoxin identifies critical features of a minimal VapC4 toxin-binding module.; Journal of bacteriology; Vol 197(7). 2015 Apr. Pavelka MSMahapatra SCrick DC Genetics of Peptidoglycan Biosynthesis.; Microbiology spectrum; Vol 2(4). 2014 Aug. Sanders ANWright LFPavelka MS Genetic characterization of mycobacterial L,D-transpeptidases.; Microbiology (Reading, England); Vol 160(Pt 8). 2014 Aug. Sanders ANPavelka MS Phenotypic analysis of Eschericia coli mutants lacking L,D-transpeptidases.; Microbiology (Reading, England); Vol 159(Pt 9). 2013 Sep. Mahapatra SPiechota CGil FMa YHuang HScherman MSJones VPavelka MSMoniz-Pereira JPimentel MMcNeil MRCrick DC Mycobacteriophage Ms6 LysA: a peptidoglycan amidase and a useful analytical tool.; Applied and environmental microbiology; Vol 79(3). 2013 Feb. Slayden RAJackson MZucker JRamirez MVDawson CCCrew RSampson NSThomas STJamshidi NSisk PCaspi RCrick DCMcNeil MRPavelka MSNiederweis MSiroy ADona VMcFadden JBoshoff HLew JM Updating and curating metabolic pathways of TB.; Tuberculosis (Edinburgh, Scotland); Vol 93(1). 2013 Jan. Feiler CFisher ACBoock JTMarrichi MJWright LSchmidpeter PABlankenfeldt WPavelka MDeLisa MP Directed evolution of Mycobacterium tuberculosis β-lactamase reveals gatekeeper residue that regulates antibiotic resistance and catalytic efficiency.; PloS one; Vol 8(9). 2013. LoVullo EDMiller CNPavelka MSKawula TH TetR-based gene regulation systems for Francisella tularensis.; Applied and environmental microbiology; Vol 78(19). 2012 Oct. Patru MMPavelka MS A role for the class A penicillin-binding protein PonA2 in the survival of Mycobacterium smegmatis under conditions of nonreplication.; Journal of bacteriology; Vol 192(12). 2010 Jun. LoVullo EDMolins-Schneekloth CRSchweizer HPPavelka MS Single-copy chromosomal integration systems for Francisella tularensis.; Microbiology (Reading, England); Vol 155(Pt 4). 2009 Apr. LoVullo EDSherrill LAPavelka MS Improved shuttle vectors for Francisella tularensis genetics.; FEMS microbiology letters; Vol 291(1). 2009 Feb. Pavelka MS Allelic exchange of unmarked mutations in Mycobacterium tuberculosis.; Methods in molecular biology (Clifton, N.J.); Vol 435. 2008. McCann JRMcDonough JAPavelka MSBraunstein M Beta-lactamase can function as a reporter of bacterial protein export during Mycobacterium tuberculosis infection of host cells.; Microbiology (Reading, England); Vol 153(Pt 10). 2007 Oct. Kincaid EZWolf AJDesvignes LMahapatra SCrick DCBrennan PJPavelka MSErnst JD Codominance of TLR2-dependent and TLR2-independent modulation of MHC class II in Mycobacterium tuberculosis infection in vivo.; Journal of immunology (Baltimore, Md. : 1950); Vol 179(5). 2007 Sep 1. Titball RWSjostedt APavelka MSNano FE Biosafety and selectable markers.; Annals of the New York Academy of Sciences; Vol 1105. 2007 Jun. Pavelka MS Another brick in the wall.; Trends in microbiology; Vol 15(4). 2007 Apr. LoVullo EDSherrill LAPerez LLPavelka MS Genetic tools for highly pathogenic Francisella tularensis subsp. tularensis.; Microbiology (Reading, England); Vol 152(Pt 11). 2006 Nov. McDonough JAHacker KEFlores ARPavelka MSBraunstein M The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases.; Journal of bacteriology; Vol 187(22). 2005 Nov. Flores ARParsons LMPavelka MS Characterization of novel Mycobacterium tuberculosis and Mycobacterium smegmatis mutants hypersusceptible to beta-lactam antibiotics.; Journal of bacteriology; Vol 187(6). 2005 Mar. Consaul SAWright LFMahapatra SCrick DCPavelka MS An unusual mutation results in the replacement of diaminopimelate with lanthionine in the peptidoglycan of a mutant strain of Mycobacterium smegmatis.; Journal of bacteriology; Vol 187(5). 2005 Mar. Flores ARParsons LMPavelka MS Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.; Microbiology (Reading, England); Vol 151(Pt 2). 2005 Feb. Raymond JBMahapatra SCrick DCPavelka MS Identification of the namH gene, encoding the hydroxylase responsible for the N-glycolylation of the mycobacterial peptidoglycan.; The Journal of biological chemistry; Vol 280(1). 2005 Jan 7. Consaul SAPavelka MS Use of a novel allele of the Escherichia coli aacC4 aminoglycoside resistance gene as a genetic marker in mycobacteria.; FEMS microbiology letters; Vol 234(2). 2004 May 15. Raymond JBPrice NPPavelka MS A method for the enzymatic synthesis and HPLC purification of the peptidoglycan precursor UDP-N-acetylmuramic acid.; FEMS microbiology letters; Vol 229(1). 2003 Dec 5. Consaul SAJacobs WRPavelka MS Extragenic suppression of the requirement for diaminopimelate in diaminopimelate auxotrophs of Mycobacterium smegmatis.; FEMS microbiology letters; Vol 225(1). 2003 Aug 8. Pavelka MSChen BKelley CLCollins FMJacobs Jr WR Vaccine efficacy of a lysine auxotroph of Mycobacterium tuberculosis.; Infection and immunity; Vol 71(7). 2003 Jul. Gokulan KRupp BPavelka MSJacobs WRSacchettini JC Crystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesis.; The Journal of biological chemistry; Vol 278(20). 2003 May 16. Bardarov SBardarov SPavelka MSSambandamurthy VLarsen MTufariello JChan JHatfull GJacobs WR Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.; Microbiology (Reading, England); Vol 148(Pt 10). 2002 Jan. Pavelka MSJacobs WR Comparison of the construction of unmarked deletion mutations in Mycobacterium smegmatis, Mycobacterium bovis bacillus Calmette-Guérin, and Mycobacterium tuberculosis H37Rv by allelic exchange.; Journal of bacteriology; Vol 181(16). 1999 Aug. Pavelka MSWeisbrod TRJacobs WR Cloning of the dapB gene, encoding dihydrodipicolinate reductase, from Mycobacterium tuberculosis.; Journal of bacteriology; Vol 179(8). 1997 Apr. Pavelka MSJacobs WR Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis.; Journal of bacteriology; Vol 178(22). 1996 Nov. Balasubramanian VPavelka MSBardarov SSMartin JWeisbrod TRMcAdam RABloom BRJacobs WR Allelic exchange in Mycobacterium tuberculosis with long linear recombination substrates.; Journal of bacteriology; Vol 178(1). 1996 Jan. Pavelka MSHayes SFSilver RP Characterization of KpsT, the ATP-binding component of the ABC-transporter involved with the export of capsular polysialic acid in Escherichia coli K1.; The Journal of biological chemistry; Vol 269(31). 1994 Aug 5. Pavelka MSWright LFSilver RP Identification of two genes, kpsM and kpsT, in region 3 of the polysialic acid gene cluster of Escherichia coli K1.; Journal of bacteriology; Vol 173(15). 1991 Aug.