Publications
Publications
- Alcohol and vascular endothelial function: Biphasic effect highlights the importance of dose.; Alcohol, clinical & experimental research; Vol 47(8), pp. 1467-1477. 2023 Jul 10.
- Caveolin-1 inhibition mediates the opposing effects of alcohol on γ-secretase activity in arterial endothelial and smooth muscle cells.; Physiological reports; Vol 11(1), pp. e15544. 2023 Jan.
- Exosomal Composition, Biogenesis and Profiling Using Point-of-Care Diagnostics-Implications for Cardiovascular Disease.; Frontiers in cell and developmental biology; Vol 10, pp. 853451. 2022 Jun 01.
- Moderate dose alcohol protects against serum amyloid protein A1-induced endothelial dysfunction via both notch-dependent and notch-independent pathways.; Alcoholism, clinical and experimental research. 2021 Sep 29.
- Disease-Relevant Single Cell Photonic Signatures Identify S100β Stem Cells and their Myogenic Progeny in Vascular Lesions.; Stem cell reviews and reports. 2021 Mar 17.
- The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions.; NPJ Regenerative medicine; Vol 6(1). 2021 Mar 01.
- Moderate Alcohol Consumption Targets S100β+ Vascular Stem Cells and Attenuates Injury-Induced Neointimal Hyperplasia.; Alcoholism, clinical and experimental research; Vol 44(9). 2020 Sep.
- Label-Free Multi Parameter Optical Interrogation of Endothelial Activation in Single Cells using a Lab on a Disc Platform.; Scientific reports; Vol 9(1). 2019 Mar 11.
- Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease.; Frontiers in cardiovascular medicine; Vol 6. 2019.
- Differential effects of alcohol and its metabolite acetaldehyde on vascular smooth muscle cell Notch signaling and growth.; American journal of physiology. Heart and circulatory physiology; Vol 314(1). 2018 Jan 01.
- Alcohol Reduces Arterial Remodeling by Inhibiting Sonic Hedgehog-Stimulated Stem Cell Antigen-1 Positive Progenitor Stem Cell Expansion.; Alcoholism, clinical and experimental research; Vol 41(12). 2017 Dec.
- Nox, Reactive Oxygen Species and Regulation of Vascular Cell Fate.; Antioxidants (Basel, Switzerland); Vol 6(4). 2017 Nov 14.
- Vascular endothelium - Gatekeeper of vessel health.; Atherosclerosis; Vol 248. 2016 May.
- Bile Salts at Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling.; Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract; Vol 20(3). 2016 Mar.
- Ethanol inhibits γ-secretase proteolytic activity in vascular smooth muscle cells.; Alcoholism, clinical and experimental research; Vol 39(11). 2015 Nov.
- Differential expression of Hedgehog/Notch and transforming growth factor-β in human abdominal aortic aneurysms.; Journal of vascular surgery; Vol 62(2). 2015 Aug.
- Hedgehog and Resident Vascular Stem Cell Fate.; Stem cells international; Vol 2015. 2015.
- Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells.; Cell and tissue research; Vol 358(1). 2014 Oct.
- Glucose attenuates hypoxia-induced changes in endothelial cell growth by inhibiting HIF-1α expression.; Diabetes & vascular disease research; Vol 11(4). 2014 Jul.
- Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?; Vascular cell; Vol 6(1). 2014 Mar 15.
- Perivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodeling.; PloS one; Vol 9(1). 2014.
- Flk-1/KDR mediates ethanol-stimulated endothelial cell Notch signaling and angiogenic activity.; Journal of vascular research; Vol 51(4). 2014.
- Inhibition of patched-1 prevents injury-induced neointimal hyperplasia.; Arteriosclerosis, thrombosis, and vascular biology; Vol 33(8). 2013 Aug.
- Alcohol and cardiovascular disease--modulation of vascular cell function.; Nutrients; Vol 4(4). 2012 Apr.
- The NOX-ROS connection: targeting Nox1 control of N-cadherin shedding in vascular smooth muscle cells.; Cardiovascular research; Vol 93(3). 2012 Mar 01.
- Investigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease.; Expert opinion on investigational drugs; Vol 20(12). 2011 Dec.
- Differential effects of daily-moderate versus weekend-binge alcohol consumption on atherosclerotic plaque development in mice.; Atherosclerosis; Vol 219(2). 2011 Dec.
- Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of hedgehog and Notch signaling.; Investigative ophthalmology & visual science; Vol 52(7). 2011 Jun 23.
- Endothelial Grb2-associated binder 1 is crucial for postnatal angiogenesis.; Arteriosclerosis, thrombosis, and vascular biology; Vol 31(5). 2011 May.
- Glycogen synthase kinase 3 beta (GSK-3b) positively regulates Notch signaling in vascular smooth muscle cells; role in cell proliferation and survival.; Basic Res Cardiol. 2011 Jan 01.
- Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression.; Cancer research; Vol 71(2). 2011 Jan 15.
- Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathway.; Arteriosclerosis, thrombosis, and vascular biology; Vol 30(12). 2010 Dec.
- Pathogenesis of Barrett's esophagus: bile acids inhibit the Notch signaling pathway with induction of CDX2 gene expression in human esophageal cells.; Surgery; Vol 146(4). 2009 Oct.
- Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A.; Arteriosclerosis, thrombosis, and vascular biology; Vol 29(7). 2009 Jul.
- Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner.; Atherosclerosis; Vol 204(2). 2009 Jun.
- Notch and vascular smooth muscle cell phenotype.; Circulation research; Vol 103(12). 2008 Dec 05.
- Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine prehepatic portal hypertension.; American journal of physiology. Gastrointestinal and liver physiology; Vol 295(5). 2008 Nov.
- Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway.; Cardiovascular research; Vol 79(2). 2008 Jul 15.
- Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes.; Atherosclerosis; Vol 195(1). 2007 Nov.
- Cyclic strain regulates the Notch/CBF-1 signaling pathway in endothelial cells: role in angiogenic activity.; Arteriosclerosis, thrombosis, and vascular biology; Vol 27(6). 2007 Jun.
- Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion.; Journal of vascular research; Vol 44(1). 2007.
- Biomechanical regulation of hedgehog signaling in vascular smooth muscle cells in vitro and in vivo.; American journal of physiology. Cell physiology; Vol 292(1). 2007 Jan.
- Notch signaling and vascular cell fate--how vascular cells respond to stress.; Wiener klinische Wochenschrift; Vol 119(11-12 Suppl 1). 2007.
- Cyclic strain-mediated matrix metalloproteinase regulation within the vascular endothelium: A force to be reckoned with.; AJP Heart and Circulatory Physiol; Vol 292(1), pp. 28-42. 2007 Jan 01.
- Notch-mediated CBF-1/RBP-J{kappa}-dependent regulation of human vascular smooth muscle cell phenotype in vitro.; American journal of physiology. Cell physiology; Vol 289(5). 2005 Nov.
- Ethanol inhibits monocyte chemotactic protein-1 expression in interleukin-1{beta}-activated human endothelial cells.; American journal of physiology. Heart and circulatory physiology; Vol 289(4). 2005 Oct.
- Ethanol inhibits pulse pressure-induced vascular smooth muscle cell migration by differentially modulating plasminogen activator inhibitor type 1, matrix metalloproteinase-2 and -9.; Thrombosis and haemostasis; Vol 94(3). 2005 Sep.
- Cyclic strain-mediated regulation of vascular endothelial cell migration and tube formation.; Biochemical and biophysical research communications; Vol 329(2). 2005 Apr 08.
- Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro.; Circulation research; Vol 96(5). 2005 Mar 18.
- Cyclic strain-mediated regulation of endothelial matrix metalloproteinase-2 expression and activity.; Cardiovascular research; Vol 63(4). 2004 Sep 1.
- Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway.; FASEB journal : official publication of the Federation of American Societies for Experimental Biology; Vol 18(12). 2004 Sep.
- Cyclic strain-induced endothelial MMP-2: role in vascular smooth muscle cell migration.; Biochemical and biophysical research communications; Vol 320(2). 2004 Jul 23.
- Pulse pressure-induced transmural fluid flux increases bovine aortic smooth muscle cell apoptosis in a mitogen activated protein kinase dependent manner.; Journal of vascular research; Vol 41(4). 2004 Jul.
- Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration.; Thrombosis research; Vol 114(1). 2004.
- Eicosanoids in cirrhosis and portal hypertension.; Prostaglandins & other lipid mediators; Vol 72(1-2). 2003 Oct.
- The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice.; Gastroenterology; Vol 124(5). 2003 May.
- Pulsatile flow-induced angiogenesis: role of G(i) subunits.; Arteriosclerosis, thrombosis, and vascular biology; Vol 22(10). 2002 Oct 1.
- Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells.; European journal of pharmacology; Vol 445(3). 2002 Jun 12.
- Endothelial dysfunction in cirrhosis and portal hypertension.; Pharmacology & therapeutics; Vol 89(3). 2001 Mar.
- Endothelial cells inhibit flow-induced smooth muscle cell migration: role of plasminogen activator inhibitor-1.; Circulation; Vol 103(4). 2001 Jan 30.
- Potential mechanisms for cardiovascular protective effect of ethanol.; Acta pharmacologica Sinica; Vol 21(5). 2000 May.
- Phenotype dictates the growth response of vascular smooth muscle cells to pulse pressure in vitro.; Experimental cell research; Vol 250(1). 1999 Jul 10.
- Ethanol inhibits basal and flow-induced vascular smooth muscle cell migration in vitro.; The Journal of surgical research; Vol 84(1). 1999 Jun 01.
- Ethanol enhances basal and flow-stimulated nitric oxide synthase activity in vitro by activating an inhibitory guanine nucleotide binding protein.; The Journal of pharmacology and experimental therapeutics; Vol 289(3). 1999 Jun.
- Sustained pulsatile flow regulates endothelial nitric oxide synthase and cyclooxygenase expression in co-cultured vascular endothelial and smooth muscle cells.; Journal of molecular and cellular cardiology; Vol 31(3). 1999 Mar.
- Effect of pulse pressure on vascular smooth muscle cell migration: the role of urokinase and matrix metalloproteinase.; Thrombosis and haemostasis; Vol 81(2). 1999 Feb.
- Ethanol inhibits mitogen activated protein kinase activity and growth of vascular smooth muscle cells in vitro.; European journal of pharmacology; Vol 362(2-3). 1998 Dec 04.
- Non-anticoagulant heparin increases endothelial nitric oxide synthase activity: role of inhibitory guanine nucleotide proteins.; Journal of molecular and cellular cardiology; Vol 30(12). 1998 Dec.
- Potential paracrine role of the pericardium in the regulation of cardiac function.; Cardiovascular research; Vol 40(2). 1998 Nov.
- Increased expression of endothelin receptors in the vasculature of portal hypertensive rats: role in splanchnic hemodynamics.; Hepatology (Baltimore, Md.); Vol 28(2). 1998 Aug.
- Flow-mediated regulation of G-protein expression in cocultured vascular smooth muscle and endothelial cells.; Arteriosclerosis, thrombosis, and vascular biology; Vol 18(1). 1998 Jan.
- Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: role in the hyperdynamic circulation.; Hepatology (Baltimore, Md.); Vol 27(1). 1998 Jan.
- Flow-mediated regulation of endothelin receptors in cocultured vascular smooth muscle cells: an endothelium-dependent effect.; Journal of vascular research; Vol 34(6). 1997 Nov.
- Enhanced G-protein-induced relaxation in portal hypertensive rats: role of nitric oxide.; Hepatology (Baltimore, Md.); Vol 26(1). 1997 Jul.
- Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats.; Journal of hepatology; Vol 25(3). 1996 Sep.
- Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells.; Journal of cellular physiology; Vol 166(3). 1996 Mar.
- Regulation of atrial natriuretic factor receptors in portal hypertensive rabbits.; Journal of hepatology; Vol 24(2). 1996 Feb.
- Perfused transcapillary smooth muscle and endothelial cell co-culture--a novel in vitro model.; In vitro cellular & developmental biology. Animal; Vol 31(8). 1995 Sep.
- Enhanced nitric oxide synthase activity in portal hypertensive rabbits.; Hepatology (Baltimore, Md.); Vol 22(2). 1995 Aug.
- Nitric oxide regulates angiotensin II receptors in vascular smooth muscle cells.; European journal of pharmacology; Vol 288(2). 1995 Jan 16.
- 17 beta-Estradiol inhibits flow- and acute hypoxia-induced prostacyclin release from perfused endocardial endothelial cells.; Circulation; Vol 90(5). 1994 Nov.
- The ANF-C receptor is not linked to adenylyl cyclase inhibition in bovine pulmonary artery endothelial cells.; Life sciences; Vol 51(18). 1992.
- Vascular atrial natriuretic factor receptor subtypes are not independently regulated by atrial peptides.; The Journal of biological chemistry; Vol 265(35). 1990 Dec 15.
- Atrial natriuretic factor recognizes two receptor subtypes in endothelial cells cultured from bovine pulmonary artery.; FEBS letters; Vol 269(1). 1990 Aug 20.