Publications

• 1. Yao Z
  2. Ayoub A
  3. Srinivasan V
  4. Wu J
  5. Tang C
  6. Duan R
  7. Milosavljevic A
  8. Xing L
  9. Ebetino FH
  10. Frontier AJ
  11. Boyce BF
  Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects.; Bone research; Vol 12(1), pp. 52. 2024 Sep 05.
• 1. Duan R
  2. Milton P
  3. Sittplangkoon C
  4. Liu X
  5. Sui Z
  6. Boyce BF
  7. Yao Z
  Chimeric antigen receptor dendritic cells targeted delivery of a single tumoricidal factor for cancer immunotherapy.; Cancer immunology, immunotherapy : CII; Vol 73(10), pp. 203. 2024 Aug 06.
• 1. Boyce BF
  2. Li J
  3. Yao Z
  4. Xing L
  Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis.; Endocrinology and metabolism (Seoul, Korea). 2023 Sep 26.
• 1. Li J
  2. Yao Z
  3. Liu X
  4. Duan R
  5. Yi X
  6. Ayoub A
  7. Sanders JO
  8. Mesfin A
  9. Xing L
  10. Boyce BF
  TGFβ1+CCR5+ neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.; Nature communications; Vol 14(1), pp. 159. 2023 Jan 11.
• 1. Yao Z
  2. Boyce BF
  TGFβ priming promotes TNF-induced bone erosion: a promising new target in RA?; Nature reviews. Rheumatology. 2022 Sep 16.
• 1. Liu X
  2. Yao JJ
  3. Chen Z
  4. Lei W
  5. Duan R
  6. Yao Z
  Lipopolysaccharide sensitizes the therapeutic response of breast cancer to IAP antagonist.; Frontiers in immunology; Vol 13, pp. 906357. 2022 Aug 31.
• 1. Shen G
  2. Liu X
  3. Lei W
  4. Duan R
  5. Yao Z
  Plumbagin is a NF-κB-Inducing Kinase Inhibitor with Dual Anabolic and Anti-Resorptive Effects that Prevents Menopausal-Related Osteoporosis in Mice.; The Journal of biological chemistry. 2022 Feb 27.
• 1. Yao Z
  2. Getting SJ
  3. Locke IC
  Regulation of TNF-Induced Osteoclast Differentiation.; Cells; Vol 11(1). 2021 Dec 31.
• 1. Yi X
  2. Liu X
  3. Kenney HM
  4. Duan R
  5. Lin X
  6. Schwarz E
  7. Yao Z
  TNF-polarized macrophages produce insulin like 6 peptide to stimulate bone formation in rheumatoid arthritis in mice.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021 Sep 29.
• 1. Sun S
  2. Tao J
  3. Sedghizadeh PP
  4. Cherian P
  5. Junka AF
  6. Sodagar E
  7. Xing L
  8. Boeckman RK
  9. Srinivasan V
  10. Yao Z
  11. Boyce BF
  12. Lipe B
  13. Neighbors JD
  14. Russell G
  15. McKenna CE
  16. Ebetino FH
  Bisphosphonates for delivering drugs to bone.; British journal of pharmacology. 2020 Sep 02.
• 1. Xing L
  2. Ebetino FH
  3. Boeckman RK
  4. Srinivasan V
  5. Tao J
  6. Sawyer TK
  7. Li J
  8. Yao Z
  9. Boyce BF
  Targeting anti-cancer agents to bone using bisphosphonates.; Bone. 2020 Jun 22.
• 1. Lei W
  2. Duan R
  3. Li J
  4. Liu X
  5. Huston A
  6. Boyce BF
  7. Yao Z
  The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice.; Scientific reports; Vol 10(1). 2020 Apr 24.
• 1. Li J
  2. Yi X
  3. Yao Z
  4. Chakkalakal JV
  5. Xing L
  6. Boyce BF
  TNF receptor-associated factor 6 mediates TNFα-induced skeletal muscle atrophy in mice during aging.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2020 Apr 08.
• 1. Li J
  2. Ayoub A
  3. Xiu Y
  4. Yin X
  5. Sanders JO
  6. Mesfin A
  7. Xing L
  8. Yao Z
  9. Boyce BF
  TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.; Nature communications; Vol 10(1). 2019 Jun 26.
• 1. Boyce BF
  2. Li J
  3. Xing L
  4. Yao Z
  Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption.; Frontiers in immunology; Vol 9. 2018.
• 1. Yao Z
  2. Lei W
  3. Duan R
  4. Li Y
  5. Luo L
  6. Boyce BF
  RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors.; The Journal of biological chemistry; Vol 292(24). 2017 Jun 16.
• 1. Krieger NS
  2. Yao Z
  3. Kyker-Snowman K
  4. Kim MH
  5. Boyce BF
  6. Bushinsky DA
  Increased bone density in mice lacking the proton receptor OGR1.; Kidney international; Vol 89(3). 2016 Mar.
• 1. Boyce BF
  2. Xiu Y
  3. Li J
  4. Xing L
  5. Yao Z
  NF-κB-Mediated Regulation of Osteoclastogenesis.; Endocrinology and metabolism (Seoul, Korea); Vol 30(1). 2015 Mar 27.
• 1. Bhardwaj R
  2. Yester JW
  3. Singh SK
  4. Biswas DD
  5. Surace MJ
  6. Waters MR
  7. Hauser KF
  8. Yao Z
  9. Boyce BF
  10. Kordula T
  RelB/p50 complexes regulate cytokine-induced YKL-40 expression.; Journal of immunology (Baltimore, Md. : 1950); Vol 194(6). 2015 Mar 15.
• 1. Zhao Z
  2. Hou X
  3. Yin X
  4. Li Y
  5. Duan R
  6. Boyce BF
  7. Yao Z
  TNF Induction of NF-κB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression.; PloS one; Vol 10(8). 2015.
• 1. Zhang H
  2. Hilton MJ
  3. Anolik JH
  4. Welle SL
  5. Zhao C
  6. Yao Z
  7. Li X
  8. Wang Z
  9. Boyce BF
  10. Xing L
  NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.; The Journal of clinical investigation; Vol 124(7). 2014 Jul.
• 1. Yao Z
  2. Li Y
  3. Yin X
  4. Dong Y
  5. Xing L
  6. Boyce BF
  NF-κB RelB negatively regulates osteoblast differentiation and bone formation.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 29(4). 2014 Apr.
• 1. Juneja SC
  2. Vonica A
  3. Zeiss C
  4. Lezon-Geyda K
  5. Yatsula B
  6. Sell DR
  7. Monnier VM
  8. Lin S
  9. Ardito T
  10. Eyre D
  11. Reynolds D
  12. Yao Z
  13. Awad HA
  14. Yu H
  15. Wilson M
  16. Honnons S
  17. Boyce BF
  18. Xing L
  19. Zhang Y
  20. Perkins AS
  Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.; Bone; Vol 60. 2014 Mar.
• 1. Xiu Y
  2. Xu H
  3. Zhao C
  4. Li J
  5. Morita Y
  6. Yao Z
  7. Xing L
  8. Boyce BF
  Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.; The Journal of clinical investigation; Vol 124(1). 2014 Jan.
• 1. Boyce BF
  2. Yao Z
  3. Xing L
  Functions of nuclear factor kappaB in bone.; Annals of the New York Academy of Sciences; Vol 1192. 2010 Mar.
• 1. Kiebala M
  2. Polesskaya O
  3. Yao Z
  4. Perry SW
  5. Maggirwar SB
  Nuclear factor-kappa B family member RelB inhibits human immunodeficiency virus-1 Tat-induced tumor necrosis factor-alpha production.; PloS one; Vol 5(7). 2010.
• 1. Yao Z
  2. Xing L
  3. Boyce BF
  NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism.; The Journal of clinical investigation; Vol 119(10). 2009 Oct.
• 1. Boyce BF
  2. Yao Z
  3. Xing L
  Osteoclasts have multiple roles in bone in addition to bone resorption.; Critical reviews in eukaryotic gene expression; Vol 19(3). 2009.
• 1. Yao Z
  2. Li P
  3. Zhang Q
  4. Guo R
  5. Schwarz EM
  6. Boyce BF
  7. Xing L
  Disruption of Rankl/Rank Signaling Reduces TNF-Induced Joint Inflammation In Vivo. The Open Arthritis Journal, 2009, 2, 7-13.; The Open Arthritis Journal; Vol 2, pp. 7-9. 2009 Jan 01.
• 1. Yao Z
  2. Xing L
  3. Qin C
  4. Schwarz EM
  5. Boyce BF
  Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism.; The Journal of biological chemistry; Vol 283(15). 2008 Apr 11.
• 1. Engin F
  2. Yao Z
  3. Yang T
  4. Zhou G
  5. Bertin T
  6. Jiang MM
  7. Chen Y
  8. Wang L
  9. Zheng H
  10. Sutton RE
  11. Boyce BF
  12. Lee B
  Dimorphic effects of Notch signaling in bone homeostasis.; Nature medicine; Vol 14(3). 2008 Mar.
• 1. Boyce BF
  2. Yao Z
  3. Zhang Q
  4. Guo R
  5. Lu Y
  6. Schwarz EM
  7. Xing L
  New roles for osteoclasts in bone.; Annals of the New York Academy of Sciences; Vol 1116. 2007 Nov.
• 1. Yamashita T
  2. Yao Z
  3. Li F
  4. Zhang Q
  5. Badell IR
  6. Schwarz EM
  7. Takeshita S
  8. Wagner EF
  9. Noda M
  10. Matsuo K
  11. Xing L
  12. Boyce BF
  NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.; The Journal of biological chemistry; Vol 282(25). 2007 Jun 22.
• 1. Zhang Q
  2. Lu Y
  3. Proulx ST
  4. Guo R
  5. Yao Z
  6. Schwarz EM
  7. Boyce BF
  8. Xing L
  Increased lymphangiogenesis in joints of mice with inflammatory arthritis.; Arthritis research & therapy; Vol 9(6). 2007.
• 1. Morello R
  2. Bertin TK
  3. Chen Y
  4. Hicks J
  5. Tonachini L
  6. Monticone M
  7. Castagnola P
  8. Rauch F
  9. Glorieux FH
  10. Vranka J
  11. Bächinger HP
  12. Pace JM
  13. Schwarze U
  14. Byers PH
  15. Weis M
  16. Fernandes RJ
  17. Eyre DR
  18. Yao Z
  19. Boyce BF
  20. Lee B
  CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta.; Cell; Vol 127(2). 2006 Oct 20.
• 1. Boyce BF
  2. Xing L
  3. Yao Z
  4. Yamashita T
  5. Shakespeare WC
  6. Wang Y
  7. Metcalf CA
  8. Sundaramoorthi R
  9. Dalgarno DC
  10. Iuliucci JD
  11. Sawyer TK
  SRC inhibitors in metastatic bone disease.; Clinical cancer research : an official journal of the American Association for Cancer Research; Vol 12(20 Pt 2). 2006 Oct 15.
• 1. Yao Z
  2. Li P
  3. Zhang Q
  4. Schwarz EM
  5. Keng P
  6. Arbini A
  7. Boyce BF
  8. Xing L
  Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression.; The Journal of biological chemistry; Vol 281(17). 2006 Apr 28.
• 1. Boyce BF
  2. Xing L
  3. Yao Z
  4. Shakespeare WC
  5. Wang Y
  6. Metcalf CA
  7. Sundaramoorthi R
  8. Dalgarno DC
  9. Iuliucci JD
  10. Sawyer TK
  Future anti-catabolic therapeutic targets in bone disease.; Annals of the New York Academy of Sciences; Vol 1068. 2006 Apr.
• 1. Kaneki H
  2. Guo R
  3. Chen D
  4. Yao Z
  5. Schwarz EM
  6. Zhang YE
  7. Boyce BF
  8. Xing L
  Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.; The Journal of biological chemistry; Vol 281(7). 2006 Feb 17.
• 1. Zhang Q
  2. Badell IR
  3. Schwarz EM
  4. Boulukos KE
  5. Yao Z
  6. Boyce BF
  7. Xing L
  Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2.; Arthritis and rheumatism; Vol 52(9). 2005 Sep.
• 1. Boyce BF
  2. Li P
  3. Yao Z
  4. Zhang Q
  5. Badell IR
  6. Schwarz EM
  7. O'Keefe RJ
  8. Xing L
  TNF-alpha and pathologic bone resorption.; The Keio journal of medicine; Vol 54(3). 2005 Sep.
• 1. Boyce BF
  2. Yamashita T
  3. Yao Z
  4. Zhang Q
  5. Li F
  6. Xing L
  Roles for NF-kappaB and c-Fos in osteoclasts.; Journal of bone and mineral metabolism; Vol 23 Suppl. 2005.
• 1. Kapur RP
  2. Yao Z
  3. Iida MH
  4. Clarke CM
  5. Doggett B
  6. Xing L
  7. Boyce BF
  Malignant autosomal recessive osteopetrosis caused by spontaneous mutation of murine Rank.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 19(10). 2004 Oct.
• 1. Yao Z
  2. Lafage-Proust MH
  3. Plouët J
  4. Bloomfield S
  5. Alexandre C
  6. Vico L
  Increase of both angiogenesis and bone mass in response to exercise depends on VEGF.; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research; Vol 19(9). 2004 Sep.