Labs & Centers
Center for Neural Development and Disease (CNDD)
The Center for Neural Development and Disease (CNDD) at the University of Rochester Medical Center brings together faculty from diverse departments, including Neurology, Pediatrics, Biomedical Genetics, Biochemistry and Biophysics, Ophthalmology, Emergency Medicine, and Neurobiology and Anatomy, to carry out research directed toward understanding how genes and environment build the human brain and modulate its function in health and disease
Clinical Trials Coordination Center (CTCC)
A research unit of the University of Rochester’s Department of Neurology, operates to foster multi-institutional academic research through the development, management, and reporting of hypothesis-driven, controlled clinical trials.
Fields Center for FSHD & Neuromuscular Research
The Fields Center for FSHD and Neuromuscular Research represents the first concerted international effort to accelerate aggressive and innovative clinical and genetic research to find treatments for people with facioscapulohumeral muscular dystrophy (FSHD).
The Goldman Lab - Cell and Gene Therapy
The Goldman Lab of the Center for Translational Neuromedicine focuses on the use of stem and progenitor cells for the treatment of neurodegenerative disorders such as Huntington's Disease, as well as for the treatment of glial diseases such as the pediatric leukodystrophies and multiple sclerosis. The lab also has a strong interest in the conversion of resident cells into brain cancers, and is board certified in neuro-oncology.
The Muscle Study Group (MSG), is a consortium of scientific investigators from academic and research centers who are committed to the cooperative planning, implementation, analysis and reporting of controlled clinical trials and of other research for muscle and other neuromuscular diseases.
Muscular Dystrophy Cooperative Research Center
As nationally recognized centers of excellence in muscular dystrophy, the Senator Paul D. Wellstone MDCRCs were charged with the task of establishing research programs focused on major questions about muscular dystrophy.
National Registry was developed to:
- Help people with Myotonic Dystrophy (DM) or Facioscapulohumeral Muscular Dystrophy (FSHD) participate in research on their disease
- Help investigators accomplish their research by connecting them with people who have DM or FSHD
- Encourage more research on these rare diseases
Myotonia is a state of hyperexcitability in muscle fibers in which a voluntary contraction or electromechanical stimulation can provoke trains of repetitive action potentials. This causes delay in relaxation after a muscle contraction. The repetitive action potentials are generated by the muscle fibers, independent of any input from the motor neuron. Myotonia is caused by dysfunction of ion channels in the muscle membrane.