Skip to content
Home
David Oakes, Ph.D.

David Oakes, Ph.D.

Contact

Office (585) 275-2405

About Me

Faculty Appointments

Professor (Part-Time) - Department of Biostatistics and Computational Biology (SMD)

Credentials

Education

PhD | UK - Non-Medical School. Arts & Sciences. 1972

BA | UK - Non-Medical School. Arts & Sciences. 1968

Awards

Fellow. 2005

Elected Member. 1994

Fellow. 1993

Research

After a period as Assistant Professor of Statistics at Harvard University I returned to London in 1977 as Senior Lecturer in Occupational Health Statistics at the London School of Hygiene and Tropical Medicine, where I became involved in the design and analysis of epidemiologic studies of cancer and...
After a period as Assistant Professor of Statistics at Harvard University I returned to London in 1977 as Senior Lecturer in Occupational Health Statistics at the London School of Hygiene and Tropical Medicine, where I became involved in the design and analysis of epidemiologic studies of cancer and respiratory diseases, and in the education of occupational health professionals.

Since coming to Rochester in 1983 I have become deeply involved in clinical trials of treatments for Parkinson's disease and Huntington's disease, and in cardiology. I have maintained my interest in environmental medicine through a long association with the Environmental Health Sciences Center. .

I have taught courses in undergraduate probability and statistics and a variety of graduate level courses, including probability, stochastic processes, statistical inference, statistical modeling techniques and survival analysis. I have been involved in the education of medical students and fellows. I hold a training grant in environmental health sciences biostatistics and am co-director of a training grant in experimental therapeutics in neurology. I have Chaired the Departments of Statistics (1989-95) and of Biostatistics (1995-2002 and 2007-2012)

My major research interests are in the area of univariate and multiivariate survival analysis and in the analysis of multiple event-time data. I have advised ten graduate students, Three (Ben Armstrong at London, Amita Manatunga at Emory. and Jong-Hyeon Jeong at Pittsburgh) are now full professors. Four others hold academic positions.

I am a Fellow of the American Statistical Association and the Institute of Mathematical Statistics and an elected member of the International Statistical Institute. I served on the NIH Study Sections "Biostatistical Methods and Research Design" and "Epidemiology of Cancer". I served as associate editor of the leading journal Biometrika from 1979-2008 , and am one of three Editors of the journal Lifetime Data Analysis. I have authored or co-authored over 150 publications. including methodologic papers in the statistical and biostatistical literature and collaborative works, in the medical literature. A selection of the methodologic papers is given below. My e-CV gives a complete list

Publications

Journal Articles

Cognitive Symptoms in Cross-Sectional Parkinson Disease Cohort Evaluated by Human-in-the-Loop Machine Learning and Natural Language Processing.

Purks JL, Arbatti L, Hosamath A, Amara AW, Anderson KE, Chahine L, Eberly SW, Kinel D, Mantri S, Mathur S, Oakes D, Standaert DG, Weintraub D, Shoulson I, Marras C

Neurology. Clinical practice.. 2024 October 14 (5):e200334. Epub 07/02/2024.

Association between Subjective Cognitive Complaints and Incident Functional Impairment in Parkinson's Disease.

Weintraub D, Marras C, Amara A, Anderson KE, Chahine LM, Eberly S, Hosamath A, Kinel D, Mantri S, Mathur S, Oakes D, Purks JL, Standaert DG, Shoulson I, Arbatti L

Movement disorders : official journal of the Movement Disorder Society.. 2024 April 39 (4):706-714. Epub 02/06/2024.

In Their Own Words: Fears Expressed by People with Parkinson's Disease in an Online Symptom Database.

Mantri S, Purks JL, Kinel D, Arbatti L, Hosamath A, Allen A, Amara A, Anderson K, Chahine LM, Eberly S, Mathur S, Standaert D, Oakes D, Weintraub D, Shoulson I, Marras C

Journal of Parkinson's disease.. 2024 14 (4):865-872. Epub 1900 01 01.

Relationships of B12 and Homocysteine with Outcomes in the SURE-PD, SURE-PD3, and STEADY-PDIII Trials.

Christine CW, Auinger P, Forti EAR, Tat L, Cannizzaro N, Mustafa A, Iyer JM, Oakes D, Green R

Journal of Parkinson's disease.. 2024 14 (6):1243-1255. Epub 1900 01 01.

Cox (1972): recollections and reflections.

Oakes D

Lifetime data analysis.. 2023 October 29 (4):699-708. Epub 09/15/2023.

What Patients Say: Large-Scale Analyses of Replies to the Parkinson's Disease Patient Report of Problems (PD-PROP).

Marras C, Arbatti L, Hosamath A, Amara A, Anderson KE, Chahine LM, Eberly S, Kinel D, Mantri S, Mathur S, Oakes D, Purks JL, Standaert DG, Tanner CM, Weintraub D, Shoulson I

Journal of Parkinson's disease.. 2023 13 (5):757-767. Epub 1900 01 01.

Internal tremor in people with Parkinson's Disease: Demographic characteristics and comorbid symptoms.

Chahine LM, Arbatti L, Hosamath A, Amara A, Anderson KE, Purks J, Eberly S, Kinel D, Mantri S, Mathur S, Oakes D, Standaert DG, Weintraub D, Shoulson I, Marras C

Clinical parkinsonism & related disorders.. 2023 9 :100229. Epub 11/07/2023.

The Safety of Deutetrabenazine for Chorea in Huntington Disease: An Open-Label Extension Study.

Frank S, Testa C, Edmondson MC, Goldstein J, Kayson E, Leavitt BR, Oakes D, O'Neill C, Vaughan C, Whaley J, Gross N, Gordon MF, Savola JM,

CNS drugs.. 2022 November 36 (11):1207-1216. Epub 10/15/2022.

Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial.

Feigin A, Evans EE, Fisher TL, Leonard JE, Smith ES, Reader A, Mishra V, Manber R, Walters KA, Kowarski L, Oakes D, Siemers E, Kieburtz KD, Zauderer M,

Nature medicine.. 2022 October 28 (10):2183-2193. Epub 08/08/2022.

Dissecting the Domains of Parkinson's Disease: Insights from Longitudinal Item Response Theory Modeling.

Luo S, Zou H, Stebbins GT, Schwarzschild MA, Macklin EA, Chan J, Oakes D, Simuni T, Goetz CG,

Movement disorders : official journal of the Movement Disorder Society.. 2022 September 37 (9):1904-1914. Epub 07/16/2022.

Re-Analysis of the STEADY-PD II Trial-Evidence for Slowing the Progression of Parkinson's Disease.

Surmeier DJ, Nguyen JT, Lancki N, Venuto CS, Oakes D, Simuni T, Wyse RK

Movement disorders : official journal of the Movement Disorder Society.. 2022 February 37 (2):334-342. Epub 11/12/2021.

Longitudinal Cohort Study of Verbatim-Reported Postural Instability Symptoms as Outcomes for Online Parkinson's Disease Trials.

Shoulson I, Arbatti L, Hosamath A, Eberly SW, Oakes D

Journal of Parkinson's disease.. 2022 12 (6):1969-1978. Epub 1900 01 01.

Novel Approach to Movement Disorder Society-Unified Parkinson's Disease Rating Scale Monitoring in Clinical Trials: Longitudinal Item Response Theory Models.

Luo S, Zou H, Goetz CG, Choi D, Oakes D, Simuni T, Stebbins GT

Movement disorders clinical practice.. 2021 October 8 (7):1083-1091. Epub 08/03/2021.

Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial.

, Schwarzschild MA, Ascherio A, Casaceli C, Curhan GC, Fitzgerald R, Kamp C, Lungu C, Macklin EA, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I, Videnovic A, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH, Hung A, Bwala G, Litvan I, Simon DK, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF, Crotty GF, Klements D, Kostrzebski M, McMahon GM, Pothier L, Waikar SS, Lang A, Mestre T

JAMA.. 2021 September 14326 (10):926-939. Epub 1900 01 01.

Longitudinal Change in Quality of Life in Neurological Disorders Measures Over 3?Years in Patients with Early Parkinson's Disease.

Marras C, Mills KA, Eberly S, Oakes D, Chou KL, Halverson M, Parashos SA, Tarolli CG, Lai JS, Nowinsky CJ, Suchowersky O, Farbman ES, Shulman LM, Simuni T

Movement disorders : official journal of the Movement Disorder Society.. 2021 August 36 (8):1979-1983. Epub 05/13/2021.

Isradipine plasma pharmacokinetics and exposure-response in early Parkinson's disease.

Venuto CS, Yang L, Javidnia M, Oakes D, James Surmeier D, Simuni T

Annals of clinical and translational neurology.. 2021 March 8 (3):603-612. Epub 01/18/2021.

Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD).

Schneider RB, Omberg L, Macklin EA, Daeschler M, Bataille L, Anthwal S, Myers TL, Baloga E, Duquette S, Snyder P, Amodeo K, Tarolli CG, Adams JL, Callahan KF, Gottesman J, Kopil CM, Lungu C, Ascherio A, Beck JC, Biglan K, Espay AJ, Tanner C, Oakes D, Shoulson I, Novak D, Kayson E, Ray Dorsey E, Mangravite L, Schwarzschild MA, Simuni T,

Annals of clinical and translational neurology.. 2021 February 8 (2):308-320. Epub 12/22/2020.

Predictive Value of Verbatim Parkinson's Disease Patient-Reported Symptoms of Postural Instability and Falling.

Javidnia M, Arbatti L, Hosamath A, Eberly SW, Oakes D, Shoulson I

Journal of Parkinson's disease.. 2021 11 (4):1957-1964. Epub 1900 01 01.

Cognitive impairment in Parkinson's disease: Associations between subjective and objective cognitive decline in a large longitudinal study.

Mills KA, Schneider RB, Saint-Hilaire M, Ross GW, Hauser RA, Lang AE, Halverson MJ, Oakes D, Eberly S, Litvan I, Blindauer K, Aquino C, Simuni T, Marras C

Parkinsonism & related disorders.. 2020 November 80 :127-132. Epub 09/20/2020.

Clinical and Imaging Progression in the PARS Cohort: Long-Term Follow-up.

Siderowf A, Jennings D, Stern M, Seibyl J, Eberly S, Oakes D, Marek K,

Movement disorders : official journal of the Movement Disorder Society.. 2020 September 35 (9):1550-1557. Epub 07/13/2020.

Reply to "Studying reproducibility of data-driven Parkinson's disease subtypes".

Mestre TA, Eberly S, Tanner C, Grimes D, Lang AE, Oakes D, Marras C

Parkinsonism & related disorders.. 2019 September 66 :245-246. Epub 12/28/2018.

The choice not to undergo genetic testing for Huntington disease: Results from the PHAROS study.

Anderson KE, Eberly S, Marder KS, Oakes D, Kayson E, Young A, Shoulson I,

Clinical genetics.. 2019 July 96 (1):28-34. Epub 05/15/2019.

Phenotype-genotype discrepancies in the prospective Huntington at-risk observational study.

Shoulson I, Eberly S, Oakes D, Kayson E, Young AB,

Annals of clinical and translational neurology.. 2019 June 6 (6):1046-1052. Epub 05/01/2019.

Ambient and controlled exposures to particulate air pollution and acute changes in heart rate variability and repolarization.

Breitner S, Peters A, Zareba W, Hampel R, Oakes D, Wiltshire J, Frampton MW, Hopke PK, Cyrys J, Utell MJ, Kane C, Schneider A, Rich DQ

Scientific reports.. 2019 February 139 (1):1946. Epub 02/13/2019.

The Prospective Huntington At-Risk Observational Study (PHAROS): The Emotional Well-Being, Safety and Feasibility of Long-Term Research Participation.

Kayson E, Eberly S, Anderson KE, Marder K, Shoulson I, Oakes D, Young AB, Biglan K, Hersch S,

Journal of Huntington's disease.. 2019 8 (4):435-441. Epub 1900 01 01.

Reproducibility of data-driven Parkinson's disease subtypes for clinical research.

Mestre TA, Eberly S, Tanner C, Grimes D, Lang AE, Oakes D, Marras C

Parkinsonism & related disorders.. 2018 November 56 :102-106. Epub 07/20/2018.

Survival models and health sequences: discussion.

Oakes D

Lifetime data analysis.. 2018 October 24 (4):592-594. Epub 07/11/2018.

Ranolazine in High-Risk Patients With Implanted Cardioverter-Defibrillators: The RAID Trial.

Zareba W, Daubert JP, Beck CA, Huang DT, Alexis JD, Brown MW, Pyykkonen K, McNitt S, Oakes D, Feng C, Aktas MK, Ayala-Parades F, Baranchuk A, Dubuc M, Haigney M, Mazur A, McPherson CA, Mitchell LB, Natale A, Piccini JP, Raitt M, Rashtian MY, Schuger C, Winters S, Worley SJ, Ziv O, Moss AJ,

Journal of the American College of Cardiology.. 2018 August 772 (6):636-645. Epub 1900 01 01.

Selected health and lifestyle factors, cytosine-adenine-guanine status, and phenoconversion in Huntington's disease.

Tanner C, Marder K, Eberly S, Biglan K, Oakes D, Shoulson I,

Movement disorders : official journal of the Movement Disorder Society.. 2018 March 33 (3):472-478. Epub 01/03/2018.

Cognition and the course of prodromal Parkinson's disease.

Weintraub D, Chahine LM, Hawkins KA, Siderowf A, Eberly S, Oakes D, Seibyl J, Stern MB, Marek K, Jennings D,

Movement disorders : official journal of the Movement Disorder Society.. 2017 November 32 (11):1640-1645. Epub 10/24/2017.

The CREST-E study of creatine for Huntington disease: A randomized controlled trial.

Hersch SM, Schifitto G, Oakes D, Bredlau AL, Meyers CM, Nahin R, Rosas HD,

Neurology.. 2017 August 889 (6):594-601. Epub 07/12/2017.

Conversion to Parkinson Disease in the PARS Hyposmic and Dopamine Transporter-Deficit Prodromal Cohort.

Jennings D, Siderowf A, Stern M, Seibyl J, Eberly S, Oakes D, Marek K,

JAMA neurology.. 2017 August 174 (8):933-940. Epub 1900 01 01.

Safety of Converting From Tetrabenazine to Deutetrabenazine for the Treatment of Chorea.

Frank S, Stamler D, Kayson E, Claassen DO, Colcher A, Davis C, Duker A, Eberly S, Elmer L, Furr-Stimming E, Gudesblatt M, Hunter C, Jankovic J, Kostyk SK, Kumar R, Loy C, Mallonee W, Oakes D, Scott BL, Sung V, Goldstein J, Vaughan C, Testa CM,

JAMA neurology.. 2017 August 174 (8):977-982. Epub 1900 01 01.

Factors related to genetic testing in adults at risk for Huntington disease: the prospective Huntington at-risk observational study (PHAROS).

Quaid KA, Eberly SW, Kayson-Rubin E, Oakes D, Shoulson I,

Clinical genetics.. 2017 June 91 (6):824-831. Epub 11/24/2016.

A novel design of a Phase III trial of isradipine in early Parkinson disease (STEADY-PD III).

Biglan KM, Oakes D, Lang AE, Hauser RA, Hodgeman K, Greco B, Lowell J, Rockhill R, Shoulson I, Venuto C, Young D, Simuni T,

Annals of clinical and translational neurology.. 2017 June 4 (6):360-368. Epub 05/09/2017.

Multicenter Cardiovascular Studies and Trials: Lessons Learned From 35 Years of Productive Collaboration.

Moss AJ, ,

Journal of the American College of Cardiology.. 2016 November 1568 (20):2232-2234. Epub 1900 01 01.

Does total antioxidant capacity modify adverse cardiac responses associated with ambient ultrafine, accumulation mode, and fine particles in patients undergoing cardiac rehabilitation?

Wang M, Utell MJ, Schneider A, Zareba W, Frampton MW, Oakes D, Hopke PK, Wiltshire J, Kane C, Peters A, Breitner S, Chalupa D, Rich DQ

Environmental research.. 2016 August 149 :15-22. Epub 05/10/2016.

Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial.

, Frank S, Testa CM, Stamler D, Kayson E, Davis C, Edmondson MC, Kinel S, Leavitt B, Oakes D, O'Neill C, Vaughan C, Goldstein J, Herzog M, Snively V, Whaley J, Wong C, Suter G, Jankovic J, Jimenez-Shahed J, Hunter C, Claassen DO, Roman OC, Sung V, Smith J, Janicki S, Clouse R, Saint-Hilaire M, Hohler A, Turpin D, James RC, Rodriguez R, Rizer K, Anderson KE, Heller H, Carlson A, Criswell S, Racette BA, Revilla FJ, Nucifora F, Margolis RL, Ong M, Mendis T, Mendis N, Singer C, Quesada M, Paulsen JS, Brashers-Krug T, Miller A, Kerr J, Dubinsky RM, Gray C, Factor SA, Sperin E, Molho E, Eglow M, Evans S, Kumar R, Reeves C, Samii A, Chouinard S, Beland M, Scott BL, Hickey PT, Esmail S, Fung WL, Gibbons C, Qi L, Colcher A, Hackmyer C, McGarry A, Klos K, Gudesblatt M, Fafard L, Graffitti L, Schneider DP, Dhall R, Wojcieszek JM, LaFaver K, Duker A, Neefus E, Wilson-Perez H, Shprecher D, Wall P, Blindauer KA, Wheeler L, Boyd JT, Houston E, Farbman ES, Agarwal P, Eberly SW, Watts A, Tariot PN, Feigin A, Evans S, Beck C, Orme C, Edicola J, Christopher E

JAMA.. 2016 July 5316 (1):40-50. Epub 1900 01 01.

Cognition in individuals at risk for Parkinson's: Parkinson associated risk syndrome (PARS) study findings.

Chahine LM, Weintraub D, Hawkins KA, Siderowf A, Eberly S, Oakes D, Seibyl J, Stern MB, Marek K, Jennings D,

Movement disorders : official journal of the Movement Disorder Society.. 2016 January 31 (1):86-94. Epub 08/21/2015.

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.

, Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C

JAMA neurology.. 2016 January 73 (1):102-10. Epub 1900 01 01.

On the win-ratio statistic in clinical trials with multiple types of event

Oakes, D.

Biometrika. 2016; 103(3): 742-745.

Early Clinical Predictors of Treatment-Resistant and Functional Outcomes in Parkinson's Disease.

Kurlan R, Ravina B, Eberly S, Lang AE, Tanner CM, Marek K, Marder K, Beck J, Elliott R, Oakes D, Shoulson I,

Movement disorders clinical practice.. 2016 3 (1):53-58. Epub 12/14/2015.

Association between ?-synuclein blood transcripts and early, neuroimaging-supported Parkinson's disease.

Locascio JJ, Eberly S, Liao Z, Liu G, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Dhima K, Hung AY, Flaherty AW, Schwarzschild MA, Hayes MT, Wills AM, Shivraj Sohur U, Mejia NI, Selkoe DJ, Oakes D, Shoulson I, Dong X, Marek K, Zheng B, Ivinson A, Hyman BT, Growdon JH, Sudarsky LR, Schlossmacher MG, Ravina B, Scherzer CR

Brain : a journal of neurology.. 2015 September 138 (Pt 9):2659-71. Epub 07/28/2015.

Improving clinical practice guidelines for practicing cardiologists.

Benhorin J, Bodenheimer M, Brown M, Case R, Dwyer EM, Eberly S, Francis C, Gillespie JA, Goldstein RE, Greenberg H, Haigney M, Krone RJ, Klein H, Lichstein E, Locati E, Marcus FI, Moss AJ, Oakes D, Ryan DH, Bloch Thomsen PE, Zareba W,

The American journal of cardiology.. 2015 June 15115 (12):1773-6. Epub 03/24/2015.

Cardiovascualr effects of ozone in healthy subjects with and without deletion of glutathione S-transferase M1.

Farmpton, M.W.; Pietropaoli, A., Dentler, M.; Chalupa, D; Little, E. L; Stewart L.; Frasier, M.; Oakes, D.; Wiltshire, J.; Vora, R.; and Utell, M.J.

Inhalation Toxicology. 2015; 27: 113-119.

Informativeness of Early Huntington Disease Signs about Gene Status.

Oster E, Eberly SW, Dorsey ER, Kayson-Rubin E, Oakes D, Shoulson I

Journal of Huntington's disease.. 2015 4 (3):271-7. Epub 1900 01 01.

Imaging prodromal Parkinson disease: the Parkinson Associated Risk Syndrome Study.

Jennings D, Siderowf A, Stern M, Seibyl J, Eberly S, Oakes D, Marek K,

Neurology.. 2014 November 483 (19):1739-46. Epub 10/08/2014.

Acute Changes in Ambient Temperature Are Associated With Adverse Changes in Cardiac Rhythm.

Wasserman EB, Zareba W, Utell MJ, Oakes D, Hopke PK, Frampton M, Chalupa D, Beckett W, Rich DQ

Air quality, atmosphere, & health.. 2014 September 17 (3):357-367. Epub 1900 01 01.

Longitudinal follow-up of SWEDD subjects in the PRECEPT Study.

Marek K, Seibyl J, Eberly S, Oakes D, Shoulson I, Lang AE, Hyson C, Jennings D,

Neurology.. 2014 May 2082 (20):1791-7. Epub 04/23/2014.

A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit.

, Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K

JAMA neurology.. 2014 May 71 (5):543-52. Epub 1900 01 01.

Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial.

, Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D, Rudolph A, Shoulson I, Tennis MK, Espay AJ, Gartner M, Hung A, Bwala G, Lenehan R, Encarnacion E, Ainslie M, Castillo R, Togasaki D, Barles G, Friedman JH, Niles L, Carter JH, Murray M, Goetz CG, Jaglin J, Ahmed A, Russell DS, Cotto C, Goudreau JL, Russell D, Parashos SA, Ede P, Saint-Hilaire MH, Thomas CA, James R, Stacy MA, Johnson J, Gauger L, Antonelle de Marcaida J, Thurlow S, Isaacson SH, Carvajal L, Rao J, Cook M, Hope-Porche C, McClurg L, Grasso DL, Logan R, Orme C, Ross T, Brocht AF, Constantinescu R, Sharma S, Venuto C, Weber J, Eaton K

JAMA neurology.. 2014 February 71 (2):141-50. Epub 1900 01 01.

Inhalation of ultrafine aprticles alters heart rate and heart rate variability in people with type II dibetes.

Vora, R.; Zareba, W.; Utell, M.J.; Pietropaoli, A.; Chalupa, D.; Little, E.; Oakes, D.; Bausch, J.; Wiltshire, J;, Frampton, M.

Particle and Fibre Technology. 2014; 11(31).

Impact of disclosure of individual imaging results in a multi-center Parkinson clinical trial.

Jennings D, Eberly S, Oakes D, Seibyl J, Marek K, Shoulson I

Journal of Parkinson's disease.. 2014 4 (4):629-38. Epub 1900 01 01.

Natural history of Huntington disease.

Dorsey ER, Beck CA, Darwin K, Nichols P, Brocht AF, Biglan KM, Shoulson I,

JAMA neurology.. 2013 December 70 (12):1520-30. Epub 1900 01 01.

An introduction to survival models: in honor of Ross Prentice.

Oakes D

Lifetime data analysis.. 2013 October 19 (4):442-62. Epub 07/06/2013.

HTRF analysis of soluble huntingtin in PHAROS PBMCs.

Moscovitch-Lopatin M, Goodman RE, Eberly S, Ritch JJ, Rosas HD, Matson S, Matson W, Oakes D, Young AB, Shoulson I, Hersch SM,

Neurology.. 2013 September 2481 (13):1134-40. Epub 08/21/2013.

Characterization of the Huntington intermediate CAG repeat expansion phenotype in PHAROS.

Killoran A, Biglan KM, Jankovic J, Eberly S, Kayson E, Oakes D, Young AB, Shoulson I

Neurology.. 2013 May 2880 (22):2022-7. Epub 04/26/2013.

Senior academic physicians and retirement considerations.

Moss AJ, Greenberg H, Dwyer EM, Klein H, Ryan D, Francis C, Marcus F, Eberly S, Benhorin J, Bodenheimer M, Brown M, Case R, Gillespie J, Goldstein R, Haigney M, Krone R, Lichstein E, Locati E, Oakes D, Thomsen PE, Zareba W

Progress in cardiovascular diseases.. 2013 55 (6):611-5. Epub 03/21/2013.

Reduction in inappropriate therapy and mortality through ICD programming.

Moss AJ, Schuger C, Beck CA, Brown MW, Cannom DS, Daubert JP, Estes NA, Greenberg H, Hall WJ, Huang DT, Kautzner J, Klein H, McNitt S, Olshansky B, Shoda M, Wilber D, Zareba W,

The New England journal of medicine.. 2012 December 13367 (24):2275-83. Epub 11/06/2012.

Effects of outdoor air pollutants on platelet activation in people with type 2 diabetes.

Frampton MW, Bausch J, Chalupa D, Hopke PK, Little EL, Oakes D, Stewart JC, Utell MJ

Inhalation toxicology.. 2012 October 24 (12):831-8. Epub 1900 01 01.

Are ambient ultrafine, accumulation mode, and fine particles associated with adverse cardiac responses in patients undergoing cardiac rehabilitation?

Rich DQ, Zareba W, Beckett W, Hopke PK, Oakes D, Frampton MW, Bisognano J, Chalupa D, Bausch J, O'Shea K, Wang Y, Utell MJ

Environmental health perspectives.. 2012 August 120 (8):1162-9. Epub 04/27/2012.

Piecing together the puzzle of progression and mortality in Parkinson's disease.

Marras C, Oakes D

British journal of clinical pharmacology.. 2012 August 74 (2):264-6. Epub 1900 01 01.

Impaired olfaction and other prodromal features in the Parkinson At-Risk Syndrome Study.

Siderowf A, Jennings D, Eberly S, Oakes D, Hawkins KA, Ascherio A, Stern MB, Marek K,

Movement disorders : official journal of the Movement Disorder Society.. 2012 March 27 (3):406-12. Epub 01/11/2012.

Use of Tetrabenazine in Huntington Disease Patients on Antidepressants or with Advanced Disease: Results from the TETRA-HD Study.

Dorsey R, Biglan K, Eberly S, Auinger P, Brocht A, Umeh CC, Oakes D, Clarence-Smith K, Marshall F, Shoulson I, Frank S

PLoS currents.. 2011 November 133 :RRN1283. Epub 11/13/2011.

Serum Cholesterol and Progression of Parkinson's Disease: Results from DATATOP

Huang, X.; Auinger, P.; Eberly, S.; Oakes, D.; Schwarzschild, M.; Acherio, A.; Mailman, R.; Chen, H. for the Parkinson Study Group DATATOP Investigators.

PLoS ONE. 2011; 6(8): e22854.

Serum Urate and Probability of Dopaminergic Deficit in Early "Parkinson's Disease"

Schwarzschild, M.A.; Marek, K.; Eberly, S.; Oakes, D.; Shoulson, I.; Jennings, D.; Seibyl, J.; Ascherio, A. on behalf of the Parkinson Study Group PRECEPT Investigators.

Movement Disorders. 2011; 26(10): 1864-1868.

Gender differences in mortality in patients with severe sepsis or septic shock.

Pietropaoli AP, Glance LG, Oakes D, Fisher SG

Gender medicine.. 2010 October 7 (5):422-37. Epub 1900 01 01.

Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease.

Schwid SR, Bausch J, Oakes D, Schuchter L, Tanner C, Forrest M, Lang AE, Shoulson I,

Movement disorders : official journal of the Movement Disorder Society.. 2010 September 1525 (12):1801-8. Epub 1900 01 01.

Oral desipramine and topical lidocaine for vulvodynia: a randomized controlled trial.

Foster DC, Kotok MB, Huang LS, Watts A, Oakes D, Howard FM, Poleshuck EL, Stodgell CJ, Dworkin RH

Obstetrics and gynecology.. 2010 September 116 (3):583-593. Epub 1900 01 01.

Combining stratified and unstratified log-rank tests in paired survival data.

Oakes D, Feng C

Statistics in medicine.. 2010 July 2029 (16):1735-45. Epub 1900 01 01.

Gender Differences in Mortality in Patients with Severe Sepsis or Septic Shock (PDF)

Pietropaoli, A.P.; Glance, L.G.; Oakes, D.; Fisher, S.G.

Gender Medicine. 2010; 7(5): 422-437.

Cancer Incidence in a trial of an apoptotic agent for Parkinson's disease

Schwid, S.R.; Bausch, J.; Oakes, D.; Schuchter, L.; Tanner, C.; Forrest, M.; Ondrasik, J.; Lang, A.E.; Shoulson, I.; the PSG PRECEPT Investigators.

Movement Disorders. 2010; 25(12): 1801-1808.

A longitudinal program for biomarker development in Parkinson's disease: a feasibility study.

Ravina B, Tanner C, Dieuliis D, Eberly S, Flagg E, Galpern WR, Fahn S, Goetz CG, Grate S, Kurlan R, Lang AE, Marek K, Kieburtz K, Oakes D, Elliott R, Shoulson I,

Movement disorders : official journal of the Movement Disorder Society.. 2009 October 3024 (14):2081-90. Epub 1900 01 01.

Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study.

Biglan KM, Ross CA, Langbehn DR, Aylward EH, Stout JC, Queller S, Carlozzi NE, Duff K, Beglinger LJ, Paulsen JS,

Movement disorders : official journal of the Movement Disorder Society.. 2009 September 1524 (12):1763-72. Epub 1900 01 01.

IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells.

Saperstein S, Chen L, Oakes D, Pryhuber G, Finkelstein J

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.. 2009 May 29 (5):273-84. Epub 1900 01 01.

The tampon test for vulvodynia treatment outcomes research: reliability, construct validity, and responsiveness.

Foster DC, Kotok MB, Huang LS, Watts A, Oakes D, Howard FM, Stodgell CJ, Dworkin RH

Obstetrics and gynecology.. 2009 April 113 (4):825-832. Epub 1900 01 01.

Dietary Intake in Adults at Risk for Huntington Disease: Analysis of PHAROS Research Participants

Marder, K.; Zhao, H.; Eberly, S.; Tanner, C.M.; Oakes, D.; Shoulson, I.; Huntington Study Group.

Neurology. 2009; 73(5): 385-392.

Communicating clinical trial results to research participants.

Dorsey ER, Beck CA, Adams M, Chadwick G, de Blieck EA, McCallum C, Briner L, Deuel L, Clarke A, Stewart R, Shoulson I,

Archives of neurology.. 2008 December 65 (12):1590-5. Epub 1900 01 01.

Fatigue in levodopa-naive subjects with Parkinson disease.

Schifitto G, Friedman JH, Oakes D, Shulman L, Comella CL, Marek K, Fahn S,

Neurology.. 2008 August 1271 (7):481-5. Epub 1900 01 01.

Survival methods: additional topics.

Oakes D, Peterson DR

Circulation.. 2008 June 3117 (22):2949-55. Epub 1900 01 01.

Detection of Huntington's disease decades before diagnosis: The Predict-HD study.

Paulsen, J.; Langbehn, D.R.; Stout, J.C.; Aylward, E.; Ross, C.A.; Nance, M.; Guttman, M.; Johnson, S.; MacDonald, M.; Beglinger, L.J.; Duff, K.; Kayson, E.; Biglan, K.; Shoulson, I.; Oakes, D.; Hayden, M.; The Predict-HD Investigators and Coordinators of the Huntington Study Group.

Journal of Neurology, Neurosurgery and Psychiatry. 2008; 79(8): 874-880.

Fear of health insurance loss among individuals at risk of Huntington's disease

Oster, E.; Dorsey, E.R.; Bausch, J.; Shinaman, M.A.; Kayson, E.; Oakes, D.; Shoulson, I.; Quaid, K.; The Huntington Study Group PHAROS Investigators.

American Journal of Medical Genetics Part A. 2008; 146A(16): 2070-2077.

1!Serum urate as a predictor of clinical and radiographic progression in Parkinson;s disease

Schwarzschild, M.A.; Schwid, S.R.; Marek, K.; Watts, A.; Lang, A.E.; Oakes, D.; Shoulson, I.; Ascherio, A.; The Parkinson Study Group PRECEPT Investigators.

Archives of Neurology. 2008; 65(6): 716-723.

Publication Link

Solomon, A.C.; Stout, J.C.; Johnson, S.A.; Langbehn, D.R.; Aylward, E.H.; Brandt, L.; Ross, C.A.; Beglinger, L.; Hayden, M.R.; Kieburtz, K.:, Kayson, E.; Julian-Barosi, E.; Duff, K.; Guttman, M.; Nance M.; Oakes, D.; Shoulson, I.; Penziner, E.; Paulsen, J.S.; The Predict-HD investigators of the Huntington Study Group.

Verbal episodic memory declines prior to diagnosis

Atherosclerotic risk genotypes and recurrent coronary events after myocardial infarction.

Moss AJ, Ryan D, Oakes D, Goldstein RE, Greenberg H, Bodenheimer MM, Brown MW, Case RB, Dwyer EM, Eberly SW, Francis CW, Gillespie JA, Krone RJ, Lichstein E, MacCluer JW, Marcus FI, McCarthy J, Sparks CE, Zareba W

The American journal of cardiology.. 2005 July 1596 (2):177-82. Epub 1900 01 01.

Effects of lipids and lipid-lowering therapy on hemostatic factors in patients with myocardial infarction.

Kaba NK, Francis CW, Moss AJ, Zareba W, Oakes D, Knox KL, Fernández ID, Rainwater DL,

Journal of thrombosis and haemostasis : JTH.. 2004 May 2 (5):718-25. Epub 1900 01 01.

Randomized clinical trial of pacifier use and bottle-feeding or cupfeeding and their effect on breastfeeding.

Howard CR, Howard FM, Lanphear B, Eberly S, deBlieck EA, Oakes D, Lawrence RA

Pediatrics.. 2003 March 111 (3):511-8. Epub 1900 01 01.

Reliability of reported age at onset for Parkinson's disease.

Reider CR, Halter CA, Castelluccio PF, Oakes D, Nichols WC, Foroud T,

Movement disorders : official journal of the Movement Disorder Society.. 2003 March 18 (3):275-279. Epub 1900 01 01.

Design and analysis of two-period studies of potentially disease-modifying treatments.

McDermott MP, Hall WJ, Oakes D, Eberly S

Controlled clinical trials. 2002 December 23 (6):635-49. Epub 1900 01 01.

Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial.

Shoulson I, Oakes D, Fahn S, Lang A, Langston JW, LeWitt P, Olanow CW, Penney JB, Tanner C, Kieburtz K, Rudolph A,

Annals of neurology.. 2002 May 51 (5):604-12. Epub 1900 01 01.

Association of C-reactive protein and serum amyloid A with recurrent coronary events in stable patients after healing of acute myocardial infarction.

Harb TS, Zareba W, Moss AJ, Ridker PM, Marder VJ, Rifai N, Miller Watelet LF, Arora R, Brown MW, Case RB, Dwyer EM, Gillespie JA, Goldstein RE, Greenberg H, Hochman J, Krone RJ, Liang CS, Lichstein E, Little W, Marcus FI, Oakes D, Sparks CE, VanVoorhees L,

The American journal of cardiology.. 2002 January 1589 (2):216-21. Epub 1900 01 01.

Prevalence and penetrance of HFE mutations in 4865 unselected primary care patients.

Phatak PD, Ryan DH, Cappuccio J, Oakes D, Braggins C, Provenzano K, Eberly S, Sham RL

Blood cells, molecules & diseases.. 2002 29 (1):41-7. Epub 1900 01 01.

The productivity and impact of the Leukemia & Lymphoma Society Scholar Program: the apparent positive effect of peer review.

Lichtman MA, Oakes D

Blood cells, molecules & diseases.. 2001 27 (6):1020-7. Epub 1900 01 01.

Detection of a group of risk factors in coronary disease using a new carriership analysis approach.

Watelet LF, Moss AJ, Zareba W, Oakes D, Ryan D

The American journal of cardiology.. 2000 December 186 (11):1253-6, A6. Epub 1900 01 01.

Association between nurse-physician collaboration and patient outcomes in three intensive care units.

Baggs JG, Schmitt MH, Mushlin AI, Mitchell PH, Eldredge DH, Oakes D, Hutson AD

Critical care medicine.. 1999 September 27 (9):1991-8. Epub 1900 01 01.

Thrombogenic factors and recurrent coronary events.

Moss AJ, Goldstein RE, Marder VJ, Sparks CE, Oakes D, Greenberg H, Weiss HJ, Zareba W, Brown MW, Liang CS, Lichstein E, Little WC, Gillespie JA, Van Voorhees L, Krone RJ, Bodenheimer MM, Hochman J, Dwyer EM, Arora R, Marcus FI, Watelet LF, Case RB

Circulation.. 1999 May 1899 (19):2517-22. Epub 1900 01 01.

Direct calculation of the information matrix via the EM algorithm

Oakes, D.

Journal of the Royal Statistical Society. 1999; 61: 479-482.

Low dose clozapine for the treatment of drug-induced psychosis in Parkinson's Disease: results of the double-blind placebo-controlled PSYCLOPS trial.

Parkinson Study Group (D. Oakes, Chief Biostatistician).

New England Journal of Medicine. 1999; : 757-763.

The Placebo Response in Parkinson's Disease.

Shetty, N., Friedman, J.H., Kieburtz, K., Marshall, F.J., Oakes, D., and the Parkinson Study Group.

Clinical Neuropharmacology. 1999; 4: 207-212.

Parametric analysis of matched pairs survival data.

Manatunga, A.K. and Oakes, D.

Lifetime Data Analysis. 1999; 5: 371-387.

The association between nurse-physician collaboration and patient outcomes in 3 intensive care units.

Baggs, J.G., Schmitt, M.H., Muslin, A.I., Mitchell, P.H., Eldredge, D.H., Oakes, D. and Hutson, A.D.

Critical Care Medicine. 1999; 27: 1991-1998.

Thrombogenic Factors and Recurrent Coronary Events.

Moss, A.J., Goldstein, R.E., Marder, V.J., Sparks, C.E., Oakes, D., Greenberg, H., Weiss, H.J., Zareba, W., Brown, M.W., Chang-Seng, L., Lichstein, E., Little, W.C., Gillespie, J.A., Van Voorhees, L., Krone, R.J., Bodenheimer, M.M., Hochman, J., Dwyer, E.M. Jr., Arora, R., Marcus, F.I., Miller Watelet, L.F., Case, R.B.

Circulation. 1999; 99: 2517-2522.

Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease.

Huntington Study Group (D. Oakes, Chief Biostatistician).

Neurology. 1998; 50: 1366-1373.

Mortality in DATATOP: a multicenter trial in early Parkinson's disease.

Parkinson Study Group (D. Oakes, Chief Biostatistician).

Annals of Neurology. 1998; : 318-325.

Additive hazards regression with current status data.

Lin, D.Y., Oakes, D. and Ying, Z.

Biometrika. 1998; 85: 289-298.

DATATOP: A decade of neuroprotective inquiry.

Shoulson, I. And the Parkinson Study Group (D. Oakes, Chief Biostatistician).

Annals of Neurology. 1998; 85: S100-S166.

Frailty models and rank tests.

Oakes, D. and Jeong, J.-H.

Lifetime Data Analysis. 1998; : 209-228.

Frailty models and rank tests.

Oakes D, Jeong JH

Lifetime data analysis.. 1998 4 (3):209-28. Epub 1900 01 01.

Nurse-physician collaboration and satisfaction with the decision-making process in three critical care units.

Baggs JG, Schmitt MH, Mushlin AI, Eldredge DH, Oakes D, Hutson AD

American journal of critical care : an official publication, American Association of Critical-Care Nurses.. 1997 September 6 (5):393-9. Epub 1900 01 01.

A randomized, double-blind trial of parenteral low dose versus high dose interferon-beta in combination with cryotherapy for treatment of condyloma acuminatum.

Bonnez W, Oakes D, Bailey-Farchione A, Choi A, Hallahan D, Corey L, Barnum G, Pappas PG, Halloway M, Stoler MH, Reichman RC

Antiviral research.. 1997 June 35 (1):41-52. Epub 1900 01 01.

Bias in GEE estimates of population average parameters from longitudinal data.

Emond, M.J., Ritz, J. and Oakes, D.

Communications in Statistics. 1997; 26: 15-32.

The need for levodopa as an endpoint of Parkinson's Disease progression in a clinical trial of selegiline and alpha-tocopherol.

LeWitt, P., Oakes, D., Cui, L., and the Parkinson Study Group.

Movement Disorders. 1997; 12: 183-189.

A randomized, double-blind trial of parenteral low dose versus high dose interferon-² in combination with cryotherapy for treatment of condyloma acuminatum.

Bonnez, W., Oakes, D., Bailey-Farchione, A., Choi, A., Hallahan, D., Corey, L., Barnum, G., Pappas, P.G., Halloway, M., Stoler, M.H. and Reichman, R.C.

Antiviral Research. 1997; 35: 41-52.

Nurse-physician collaboration and satisfaction with the decision-making process in three critical care units.

Baggs, J.G., Schmitt, M.H., Mushlin, A.I., Eldredge, D.H., Oakes, D. and Hutson, A.

American Journal of Critical Care. 1997; 6: 393-399.

Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients not requiring levodopa.

Parkinson Study Group. (D. Oakes, Chief Biostatistician).

Annals of Neurology. 1996; 39(1): 37-45.

Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects requiring levodopa.

Parkinson Study Group. (D. Oakes, Chief Biostatistician).

Annals of Neurology. 1996; 39(1): 29-36.

A measure of association for bivariate frailty distributions.

Manatunga, A.K. and Oakes, D.

Journal of Multivariate Analysis. 1996; 56(1): 60-74.

Therapeutic efficacy and complications of excisional biopsy of condyloma acuminatum.

Bonnez, W., Oakes, D., Choi, A., D'Arcy, S.J., Pappas, P.G., Corey, L., Stoler, M.H., Demeter, L.M. and Reichman, R.C.

Sexually Transmitted Diseases. 1996; 23(4): 273-276.

Therapeutic efficacy and complications of excisional biopsy of condyloma acuminatum.

Bonnez W, Oakes D, Choi A, d'Arcy SJ, Pappas PG, Corey L, Stoler MH, Demeter LM, Reichman RC

Sexually transmitted diseases.. 1996 23 (4):273-6. Epub 1900 01 01.

A randomized, double-blind, placebo-controlled trial of systemically administered interferon-alpha, -beta, or -gamma in combination with cryotherapy for the treatment of condyloma acuminatum.

Bonnez W, Oakes D, Bailey-Farchione A, Choi A, Hallahan D, Pappas P, Holloway M, Corey L, Barnum G, Dunne A

The Journal of infectious diseases.. 1995 May 171 (5):1081-9. Epub 1900 01 01.

Cerebrospinal fluid homovanillic acid in the DATATOP study on Parkinsons disease.

Parkinson Study Group. (D. Oakes, Chief Biostatistician).

Archives of Neurobiology. 1995; 52: 237-245.

Multiple time scales in survival analysis.

Oakes D

Lifetime data analysis.. 1995 1 (1):7-18. Epub 1900 01 01.

A controlled trial of lazabemide (Ro 19-6327) in levodopa-treated Parkinson's disease. Parkinson Study Group.

Archives of neurology.. 1994 April 51 (4):342-7. Epub 1900 01 01.

A note on semiparametric inference for modulated renewal processes.

Oakes, D. and Cui, L.

Biometrika. 1994; 81: 83-90.

Multivariate survival distributions.

Oakes, D.

Nonparametric Statistics. 1994; 3: 343-354.

A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease. Parkinson Study Group.

Annals of neurology.. 1993 April 33 (4):350-6. Epub 1900 01 01.

Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease.

The New England journal of medicine.. 1993 January 21328 (3):176-83. Epub 1900 01 01.

A note on the Kaplan-Meier estimator.

Oakes, D.

American Statistician. 1993; 47: 39-40.

Use of compliance measures in an analysis of the effect of diltiazem on mortality and reinfarction after myocardial infarction.

Oakes, D., Moss, A.J., Fleiss, J.L., Bigger, J.T., Therneau, T., Eberly, S.W., McDermott, M.P., Manatunga, A., Carleen, E., Benhorin, J. and the Multicenter Diltiazem Post-Infarction Trial Research Group.

Journal of the American Statistical Association. 1993; 88: 44-49.

Markers of dopamine metabolism in Parkinson's disease. The Parkinson Study Group.

LeWitt PA, Galloway MP, Matson W, Milbury P, McDermott M, Srivastava DK, Oakes D

Neurology.. 1992 November 42 (11):2111-7. Epub 1900 01 01.

Hypolipidemic effect of type Ia antiarrhythmic agents in postinfarction patients.

Boden WE, Moss AJ, Oakes D

Circulation.. 1992 June 85 (6):2039-44. Epub 1900 01 01.

Fisher information for a bivariate extreme value distribution.

Oakes, D. and Manatunga, A.K.

Biometrika. 1992; 79: 827-832.

A new representation of Cox's score statistic and its variance.

Oakes, D. and Manatunga, A.K.

Statistics and Probability Letters. 1992; 14: 107-110.

Effects of diltiazem on long-term outcome after acute myocardial infarction in patients with and without a history of systemic hypertension. The Multicenter Diltiazem Postinfarction Trial Research Group.

Moss AJ, Oakes D, Rubison M, McDermott M, Carleen E, Eberly S, Brown M

The American journal of cardiology.. 1991 August 1568 (5):429-33. Epub 1900 01 01.

Treatment of condyloma acuminatum with three different interferon-alpha preparations administered parenterally: a double-blind, placebo-controlled trial.

Reichman RC, Oakes D, Bonnez W, Brown D, Mattison HR, Bailey-Farchione A, Stoler MH, Demeter LM, Tyring SK, Miller L

The Journal of infectious diseases.. 1990 December 162 (6):1270-6. Epub 1900 01 01.

The prognostic significance of first myocardial infarction type (Q wave versus non-Q wave) and Q wave location. The Multicenter Diltiazem Post-Infarction Research Group.

Benhorin J, Moss AJ, Oakes D, Marcus F, Greenberg H, Dwyer EM, Algeo S, Hahn E

Journal of the American College of Cardiology.. 1990 May 15 (6):1201-7. Epub 1900 01 01.

Nonfatal myocardial infarction is, by itself, an inappropriate end point in clinical trials in cardiology.

Fleiss JL, Bigger JT, McDermott M, Miller JP, Moon T, Moss AJ, Oakes D, Rolnitzky LM, Therneau TM

Circulation.. 1990 February 81 (2):684-5. Epub 1900 01 01.

Prognostic significance of nonfatal myocardial reinfarction. Multicenter Diltiazem Postinfarction Trial Research Group.

Benhorin J, Moss AJ, Oakes D

Journal of the American College of Cardiology.. 1990 February 15 (2):253-8. Epub 1900 01 01.

Deprenyl for the treatment of early Parkinson's disease.

Shoulson, I., Fahn, S., Oakes, D., Lang, A., Lanston, J.W., LeWitt, P., Olanow, W., Penney, J.B. and Tanner, C.

New England Journal of Medicine. 1990; 322: 1527-1528.

A note on residual life.

Oakes, D. and Dasu, T.

Biometrika. 1990; 77: 409-410.

Electrocardiographic subset analysis of diltiazem administration on long-term outcome after acute myocardial infarction.

Boden, W.E., Krone, R.J., Kleiger, R.E., Oakes, D., Greenberg, H., Dwyer, E.J., Jr., Miller, J.P., Abrams, J., Coromilas, J., Goldstein, R., Moss, A.J. and the Multicenter Diltiazem Post-infarction Trial Research Group.

The American Journal of Cardiology. 1990; 67: 335-342.

The interaction between diltiazem and left ventricular function after myocardial infarction. Multicenter Diltiazem Post-Infarction Research Group.

Moss AJ, Oakes D, Benhorin J, Carleen E

Circulation.. 1989 December 80 (6 Suppl):IV102-6. Epub 1900 01 01.

DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Parkinson Study Group.

Archives of neurology.. 1989 October 46 (10):1052-60. Epub 1900 01 01.

A controlled clinical trial of baclofen as protective therapy in early Huntington's disease.

Shoulson I, Odoroff C, Oakes D, Behr J, Goldblatt D, Caine E, Kennedy J, Miller C, Bamford K, Rubin A

Annals of neurology.. 1989 March 25 (3):252-9. Epub 1900 01 01.

Diltiazem and mortality and reinfarction after myocardial infarction.

Moss, A.J., Oakes, D., Bigger, J.T. (Jr.), Fleiss, J.L.

New England Journal of Medicine. 1989; 320: 124.

Bivariate survival models induced by frailties.

Oakes, D.

Journal of the American Statistical Association. 1989; 84: 487-493.

The interaction between diltiazem and left ventricular function after myocardial infarction.

Moss, A.J., Oakes, D., Benhorin, J., Carleen, E. and the Multicenter Diltiazem Postinfarction Research Group.

Circulation. 1989; 80 Supp (IV): 102-106.

Effect of deprenyl on the progression of disability in early Parkinson's disease.

Parkinson Study Group. (D. Oakes, Chief Biostatistician).

New England Journal of Medicine. 1989; 320: 1364-1371.

The effect of diltiazem on mortality and reinfarction after myocardial infarction.

The New England journal of medicine.. 1988 August 18319 (7):385-92. Epub 1900 01 01.

Long-term palliation with the classic Blalock-Taussig shunt.

Stewart S, Alexson C, Manning J, Oakes D, Eberly SW

The Journal of thoracic and cardiovascular surgery.. 1988 July 96 (1):117-21. Epub 1900 01 01.

Treatment of condyloma acuminatum with three different interferons administered intralesionally. A double-blind, placebo-controlled trial.

Reichman RC, Oakes D, Bonnez W, Greisberger C, Tyring S, Miller L, Whitley R, Carveth H, Weidner M, Krueger G

Annals of internal medicine.. 1988 May 108 (5):675-9. Epub 1900 01 01.

Mortality of workers at acetylene production plants.

Newhouse ML, Matthews G, Sheikh K, Knight KL, Oakes D, Sullivan KR

British journal of industrial medicine.. 1988 January 45 (1):63-9. Epub 1900 01 01.

Partial likelihood: applications, ramifications and generalizations

Oakes, D.

Mathematics. 1988; 80: 67-77.

Semi-parametric inference in a model for association in bivariate survival data.

Oakes, D.

Biometrika. 1986; 73: 353-361.

An approximate likelihood procedure for censored data

Oakes, D.

Biometrika. 1986; 42: 177-182.

A Master of Science Program in Medical Statistics at the University of Rochester.

Gabriel, K.R., Oakes, D. and Odoroff, C.L.

American Statistical Association, Proceedings of the Section on Statistical Education. 1986; : 24-26.

Pleural calcification in northwest Greece.

Bazas T, Oakes D, Gilson JC, Bazas B, McDonald JC

Environmental research.. 1985 December 38 (2):239-47. Epub 1900 01 01.

Mortality of welders and other craftsmen at a shipyard in NE England.

Newhouse ML, Oakes D, Woolley AJ

British journal of industrial medicine.. 1985 June 42 (6):406-10. Epub 1900 01 01.

Pulmonary function of London firemen.

Douglas DB, Douglas RB, Oakes D, Scott G

British journal of industrial medicine.. 1985 January 42 (1):55-8. Epub 1900 01 01.

Self-calibrating priors do not exist.

Oakes, D.

Journal of the American Statistical Association. 1985; 80: 390.

Mortality study of British pathologists

Oakes, D.

British Journal of Industrial Medicine. 1984; 41: 189-191.

Fugitive Emissions of Vapours from Process Equipment

Jones, A.L., Devine, M., Janes, P.R., Oakes, D. and Western, N.J.

B.O.H.S. Technical Guide. 1984; .

Survival analysis

Oakes, D.

European Journal of Operational Research. 1983; 12: 3-14.

Comparison of models for survival data.

Oakes D

Statistics in medicine.. 1983 2 (2):305-11. Epub 1900 01 01.

A concordance test for independence in the presence of censoring.

Oakes D

Biometrics.. 1982 June 38 (2):451-5. Epub 1900 01 01.

Absences attributed to respiratory diseases in welders.

Fawer RF, Gardner AW, Oakes D

British journal of industrial medicine.. 1982 May 39 (2):149-52. Epub 1900 01 01.

Effects of approximation in exposure assessments on estimated exposure-response relationships.

Armstrong, B.G. and Oakes, D.

Scandinavian Journal of Work, Environment and Health, Supplement. 1982; 1: 20-23.

Restricted cohort study designs

Oakes, D. and McDonald, J.C.

Scandinavian Journal of Work, Environment and Health. 1982; 1: 30-33.

Respiratory effects of prolonged exposure to gypsum dust

Oakes, D., Douglas, R., Knight, K., Wusteman, M. and McDonald, J.C.

Inhaled Particles (Annals of Occupational Hygiene). 1982; 26: 833-840.

A model for association in bivariate survival data.

Oakes, D.

Journal of the Royal Statistical Society (Series B). 1982; 44: 414-422.

The health and health care of doctors.

Allibone A, Oakes D, Shannon HS

The Journal of the Royal College of General Practitioners. 1981 December 31 (233):728-34. Epub 1900 01 01.

Virus warts in meat handlers.

Wall LM, Oakes D, Rycroft RJ

Contact dermatitis.. 1981 September 7 (5):259-67. Epub 1900 01 01.

Survival times: aspects of partial likelihood (with discussion)

Oakes, D.

International Statistical Review. 1981; 49: 235-264.

Matched pairs in independent Poisson processes

Oakes, D.

Journal of Applied Probability. 1979; 16: 780-793.

On log-linear hazards

Oakes, D.

Journal of the Royal Statistical Society (Series B). 1979; 41: 274-275.

Stochastic backtrackings

Oakes, D.

Stochastic Processes and their Applications. 1977; 6: 95-111.

The asymptotic information in censored survival data.

Oakes, D.

Biometrika. 1977; 64: 441-448.

The bivariate Markov process of intervals.

Oakes, D.

Information and Control. 1976; 32: 231-241.

Random overlapping intervals: A generalization of Erlang's loss formula.

Oakes, D.

Annals of Probability. 1976; 4: 940-946.

Synchronous and asynchronous distributions for Poisson cluster processes

Oakes, D.

Journal of the Royal Statistical Society (Series B). 1975; 37: 238-247.

The Markovian self-exciting process

Oakes, D.

Journal of Applied Probability. 1975; 12: 69-77.

Random walk point processes

Daley, D.J. and Oakes, D.

Zeitschrift fur Wahrscheinlichkeitstheorie und verwandte Gebiete. 1974; 30: 1-16.

A cluster process representation of self-exciting process

Hawkes, A.G. and Oakes, D.

Journal of Applied Probability. 1974; 11: 493-503.

A generalization of Moran's quasi-Poisson process

Oakes, D.

Studia Scientiarum Mathematicarum Hungarica. 1974; 9: 433-437.

Regression Models and Life-Tables (Discussion)

Oakes, D.

Journal of the Royal Statistical Society (Series B). 1972; 34: 20.

Books

Proceedings of the Second Seattle Symposium in Biostatistics (2005)

Chapter: On characterizing joint survivor functions by minima

Authors: Oakes, D

Publisher: Springer, New York 2005

Crossing Boundaries: Statistical Essays in Honor of Jack Hall (2003)

Authors: Kolassa, J.E. and Oakes, D (Eds.)

Publisher: Institute of Mathematical Statistics Lecture Notes, Monographs Series # 43 2003

Biometrika: One Hundred Years (2001)

Chapter: Biometrika Centenary: Survival Analysis

Authors: Oakes, D

Publisher: Oxford U.P., Oxford 2001

Statistics in the 21st Century (2001)

Chapter: Survival Analysis (vignette)

Authors: Oakes, D.

Publisher: Chapman and Hall/CRC, Boca Raton 2001

Encyclopedia of Biostatistics (1998)

Chapter: Duration Dependence

Authors: Oakes, D

Publisher: Wiley, New York 1998

Encyclopedia of Biostatistics (1998)

Chapter: Copula Models

Authors: Oakes, D

Publisher: Wiley, New York 1998

Proceedings of the First Seattle Symposium in Biostatistics: Survival Analysis (1997)

Chapter: Model Based and or Marginal Analysis of Multiple Event Time Data

Authors: Oakes, D

Publisher: Springer, New York 1997

Encyclopedia of Statistical Sciences Update (1997)

Chapter: Frailty models.

Authors: Oakes, D.

Publisher: Obtain 1997

Occupational Hygiene (1995)

Chapter: Statistics

Authors: Oakes, D.

Publisher: Blackwell, Oxford 1995

Survival Analysis: State of the Art (1992)

Chapter: Frailty Models for Multiple Event Times

Authors: Oakes, D

Publisher: Kluwer Academic Publishers, Netherlands 1992

Statistical Theory and Modelling: In Honour of Sir David Cox (1991)

Chapter: Life Table Analysis

Authors: Oakes, D

Publisher: Chapman and Hall, London 1991

New Antiviral Strategies (1988)

Chapter: Human papilloma viruses and treatment of condyloma acuminatum with intralesionally administered interferon

Authors: Reichman, R.C., Stoler, M.H. and Oakes, D.

Publisher: Edinburgh, Churchill Livingstone 1988

Encyclopedia of Statistical Sciences (1987)

Chapter: Semi-Parametric Models

Authors: Oakes, D

Publisher: Wiley, New York 1987

Modern Statistical Methods in Chronic Disease Epidemiology (1986)

Chapter: A model for bivariate survival data

Authors: Oakes, D

Publisher: Wiley, New York 1986

Encyclopedia of Statistical Sciences (1985)

Chapter: Oakes's Test for Concordance

Authors: Oakes, D

Publisher: Wiley, New York 1985

Analysis of Survival Data (1984)

Authors: Cox, D.R. and Oakes, D.

Publisher: Chapman and Hall, London 1984

The Neuropsychological Effects of Solvent Exposure (1983)

Chapter: Statistical Viewpoint

Authors: Oakes, D.

Publisher: Colt Foundation, Havant 1983

Occupation Hygiene (1980)

Chapter: Statistics

Authors: Oakes, D.

Publisher: Blackwell, Oxford 1980

Statistical Methods for Comparative Studies (1980)

Authors: Anderson, S., Auquier, A., Hauck, W.W., Oakes, D., Vandaele, W. and Weisberg, H.

Publisher: Wiley, New York 1980