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Richard K. Barth, Ph.D.

Richard K. Barth, Ph.D.

Contact

Call Center (585) 276-3000

About Me

Faculty Appointments

Associate Professor (Part-Time) - Department of Microbiology and Immunology (SMD)

Credentials

Education

PhD | Roswell Park Memorial Institute. Molecular Biology. 1982

BS | St Bonaventure University. Biology. 1976

Research

Patents

Prostate Specific Regulatory Nucleic Acid Sequences and Transgenic Non-Human Animals Expressing Prostate Specific Antigen

Issue date: August 08, 2000

Patent #: 6,100,444

Country: United States

Inventors: Richard K Barth, John G Frelinger, Chungwen Wei

Publications

Journal Articles

Quorum sensing: dynamic response of Pseudomonas aeruginosa to external signals.

Wagner VE, Frelinger JG, Barth RK, Iglewski BH

Trends in microbiology.. 2006 February 14 (2):55-8. Epub 01/06/2006.

Sensitivity to bleomycin-induced lung injury is not moderated by an antigen-limited T-cell repertoire.

Thatcher TH, Sime PJ, Barth RK

Experimental lung research.. 2005 September 31 (7):685-700. Epub 1900 01 01.

Keratinocyte-derived, CD80-mediated costimulation is associated with hapten-specific IgE production during contact hypersensitivity to TH1 haptens.

Burns R, Luzina I, Nasir A, Haidaris CG, Barth RK, Gaspari AA

The Journal of allergy and clinical immunology.. 2005 February 115 (2):383-90. Epub 1900 01 01.

A new murine model of humoral immuno-deficiency specifically affects class switching to T-independent antigens.

Kuzin II, Ugine GD, Barth RK, Shultz LD, Nahm MH, Young FM, Bottaro A

European journal of immunology.. 2004 July 34 (7):1807-16. Epub 1900 01 01.

Mapping susceptibility genes for the induction of pulmonary fibrosis in mice.

Barth RK, Hanchett LA, Baecher-Allan CM

Chest.. 2002 March 121 (3 Suppl):21S. Epub 1900 01 01.

Increasing the frequency of T-cell precursors specific for a cryptic epitope of hen-egg lysozyme converts it to an immunodominant epitope.

Thatcher TH, O'Brien DP, Altuwaijri S, Barth RK

Immunology.. 2000 February 99 (2):235-42. Epub 1900 01 01.

B7-1 overexpression by thymic epithelial cells results in transient and long-lasting effects on thymocytes and peripheral T helper cells but does not result in immunodeficiency.

Burns RP, Nasir A, Haake AR, Barth RK, Gaspari AA

Cellular immunology.. 1999 June 15194 (2):162-77. Epub 1900 01 01.

Regulation of human prostate-specific antigen gene expression in transgenic mice: evidence for an enhancer between the PSA and human glandular kallikrein-1 genes.

Wei C, Callahan BP, Turner MJ, Willis RA, Lord EM, Barth RK, Frelinger JG

International journal of molecular medicine.. 1998 October 2 (4):487-96. Epub 1900 01 01.

CD86 (B7-2), but not CD80 (B7-1), expression in the epidermis of transgenic mice enhances the immunogenicity of primary cutaneous Candida albicans infections.

Gaspari AA, Burns R, Nasir A, Ramirez D, Barth RK, Haidaris CG

Infection and immunity.. 1998 September 66 (9):4440-9. Epub 1900 01 01.

Cell-specific gene expression reveals changes in epithelial cell populations after bleomycin treatment.

Daly HE, Baecher-Allan CM, Paxhia AT, Ryan RM, Barth RK, Finkelstein JN

Laboratory investigation; a journal of technical methods and pathology.. 1998 April 78 (4):393-400. Epub 1900 01 01.

Characterization of the altered cutaneous reactivity of transgenic mice whose keratinocytes overexpress B7-1.

Gaspari AA, Burns RP, Kondo S, Nasir A, Kurup A, Mlodynia D, Sauder D, Barth RK

Clinical immunology and immunopathology.. 1998 March 86 (3):259-70. Epub 1900 01 01.

A transgenic strategy for analyzing the regulatory regions of the human prostate-specific antigen gene: potential applications for the treatment of prostate cancer (Review).

Willis RA, Wei C, Turner MJ, Callahan BP, Pugh AE, Barth RK, Lord EM, Frelinger JG

International journal of molecular medicine.. 1998 February 1 (2):379-86. Epub 1900 01 01.

Molecular analysis of skewed Tcra-V gene use in T-cell receptor beta-chain transgenic mice.

Burns RP, Natarajan K, LoCascio NJ, O'Brien DP, Kobori JA, Shastri N, Barth RK

Immunogenetics.. 1998 47 (2):107-14. Epub 1900 01 01.

Expression of mouse CD43 in the B cell lineage of transgenic mice causes impaired immune responses to T-independent antigens.

Ostberg JR, Dragone LL, Borrello MA, Phipps RP, Barth RK, Frelinger JG

European journal of immunology.. 1997 September 27 (9):2152-9. Epub 1900 01 01.

Elimination of T-cell-receptor beta-chain diversity in transgenic mice restricts antigen-specific but not alloreactive responses.

O'Brien DP, Baecher-Allan CM, Burns RP, Shastri N, Barth RK

Immunology.. 1997 July 91 (3):375-82. Epub 1900 01 01.

Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy.

Wei C, Willis RA, Tilton BR, Looney RJ, Lord EM, Barth RK, Frelinger JG

Proceedings of the National Academy of Sciences of the United States of America.. 1997 June 1094 (12):6369-74. Epub 1900 01 01.

Bleomycin induces strain-dependent alterations in the pattern of epithelial cell-specific marker expression in mouse lung.

Daly HE, Baecher-Allan CM, Barth RK, D'Angio CT, Finkelstein JN

Toxicology and applied pharmacology.. 1997 February 142 (2):303-10. Epub 1900 01 01.

Disregulated expression of CD43 (leukosialin, sialophorin) in the B cell lineage leads to immunodeficiency.

Ostberg JR, Dragone LL, Driskell T, Moynihan JA, Phipps R, Barth RK, Frelinger JG

The Journal of immunology : official journal of the American Association of Immunologists.. 1996 December 1157 (11):4876-84. Epub 1900 01 01.

Expression of human prostate-specific antigen (PSA) in a mouse tumor cell line reduces tumorigenicity and elicits PSA-specific cytotoxic T lymphocytes.

Wei C, Storozynsky E, McAdam AJ, Yeh KY, Tilton BR, Willis RA, Barth RK, Looney RJ, Lord EM, Frelinger JG

Cancer immunology, immunotherapy : CII.. 1996 July 42 (6):362-8. Epub 1900 01 01.

Disregulation of leukosialin (CD43, Ly48, sialophorin) expression in the B-cell lineage of transgenic mice increases splenic B-cell number and survival.

Dragone LL, Barth RK, Sitar KL, Disbrow GL, Frelinger JG

Proceedings of the National Academy of Sciences of the United States of America.. 1995 January 1792 (2):626-30. Epub 1900 01 01.

Fibroblast heterogeneity in the healing wound.

Sempowski GD, Borrello MA, Blieden TM, Barth RK, Phipps RP

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.. 1995 3 (2):120-31. Epub 1900 01 01.

Exaggerated and persistent cutaneous delayed-type hypersensitivity in transgenic mice whose epidermal keratinocytes constitutively express B7-1 antigen.

Nasir A, Ferbel B, Salminen W, Barth RK, Gaspari AA

The Journal of clinical investigation.. 1994 August 94 (2):892-8. Epub 1900 01 01.

Differential epitope expression of Ly-48 (mouse leukosialin).

Baecher-Allan CM, Kemp JD, Dorfman KS, Barth RK, Frelinger JG

Immunogenetics.. 1993 37 (3):183-92. Epub 1900 01 01.

PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis.

Baecher-Allan CM, Barth RK

Regional immunology.. 1993 5 (3-4):207-17. Epub 1900 01 01.