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John T. Langfitt, Ph.D.

John T. Langfitt, Ph.D.

Contact

Appointment (585) 341-7500
Fax (585) 442-4329
Administrative (585) 275-9403

About Me

Dr. Langfitt is a board-certified neuropsychologist who primarily evaluates adults with epilepsy, but also sees patients with other neurologic disorders (e.g., traumatic brain injury, stroke, multiple sclerosis, developmental disabilities) and psychiatric conditions that affect cognitive function (e...
Dr. Langfitt is a board-certified neuropsychologist who primarily evaluates adults with epilepsy, but also sees patients with other neurologic disorders (e.g., traumatic brain injury, stroke, multiple sclerosis, developmental disabilities) and psychiatric conditions that affect cognitive function (e.g., major depressive disorder, bipolar disorder, PTSD and somatoform disorders).

Faculty Appointments

Professor Emeritus - Department of Neurology, Epilepsy (SMD)

Credentials

Education

PhD | Boston University. Psychology. 1989

MA | Boston University. Psychology. 1985

BA | Yale University. English. 1981

Awards

Graduated cum laude. 1981

Rita Underberg Teaching Award, URMC Dept. of Psychiatry.

Greater Rochester Board Leadership Award, Rochester Business Journal.

Research

Dr. Langfitt's research focusses on the cognitive, psychiatric, quality-of-life and economic effects of epilepsy and its treatments. His expertise lies in design and implementation of clinical trials and other research designs, with a specific focus on outcomes assessment. He leads and consults on a...
Dr. Langfitt's research focusses on the cognitive, psychiatric, quality-of-life and economic effects of epilepsy and its treatments. His expertise lies in design and implementation of clinical trials and other research designs, with a specific focus on outcomes assessment. He leads and consults on a number of projects involving assessment and treatment of cognitive and neurobehavioral consequences of cerebral malaria and other pediatric infectious diseases in sub-Saharan Africa.

Publications

Journal Articles

A Case of Functional Neurological Disorder With Cognitive Symptoms: Emotion-Focused Psychotherapeutic Insights.

Millstein DJ, Perez DL, Langfitt JT

Journal of the Academy of Consultation-Liaison Psychiatry.. 2023 64 (3):307-308. Epub 04/11/2023.

Prediction of Naming Outcome With fMRI Language Lateralization in Left Temporal Epilepsy Surgery.

Gross WL, Helfand A, Swanson SJ, Conant LL, Humphries C, Raghavan M, Mueller WM, Busch RM, Allen L, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Binder JR,

Neurology.. 2022 June 798 (23):e2337-e2346. Epub 04/11/2022.

"I do lack peace, and I've run out of answers": primary caregivers' perspectives on social and behaviour problems in cerebral malaria survivors in Blantyre, Malawi.

Karmen-Tuohy S, Mboma SM, Langfitt JT, Brim R, Gladstone M, Taylor TE

Malaria journal.. 2022 April 1321 (1):123. Epub 04/13/2022.

Temporal lobe regions essential for preserved picture naming after left temporal epilepsy surgery.

Binder JR, Tong JQ, Pillay SB, Conant LL, Humphries CJ, Raghavan M, Mueller WM, Busch RM, Allen L, Gross WL, Anderson CT, Carlson CE, Lowe MJ, Langfitt JT, Tivarus ME, Drane DL, Loring DW, Jacobs M, Morgan VL, Allendorfer JB, Szaflarski JP, Bonilha L, Bookheimer S, Grabowski T, Vannest J, Swanson SJ

Epilepsia.. 2020 September 61 (9):1939-1948. Epub 08/11/2020.

Direct and indirect costs associated with stereotactic radiosurgery or open surgery for medial temporal lobe epilepsy: Results from the ROSE trial.

Langfitt JT, Quigg M, Yan G, Yu W, Ward MM, Barbaro NM, Chang EF, Broshek DK, Laxer KD, Cole AJ, Sneed PK, Hess C, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagi? A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E,

Epilepsia.. 2019 July 60 (7):1453-1461. Epub 06/11/2019.

Neurodevelopmental Impairments 1 Year After Cerebral Malaria.

Langfitt JT, McDermott MP, Brim R, Mboma S, Potchen MJ, Kampondeni SD, Seydel KB, Semrud-Clikeman M, Taylor TE

Pediatrics.. 2019 February 143 (2)Epub 01/29/2019.

Visual field defects after radiosurgery versus temporal lobectomy for mesial temporal lobe epilepsy: Findings of the ROSE trial.

Quigg M, Barbaro NM, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Newman SA, Mueller S, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagi? A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E

Seizure.. 2018 December 63 :62-67. Epub 10/31/2018.

The changing landscape of epilepsy surgery: No longer the "last resort".

Berg AT, Langfitt JT, Cascino GD

Neurology.. 2018 July 1091 (2):55-56. Epub 06/13/2018.

Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial.

Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagi? A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E

Epilepsia.. 2018 June 59 (6):1198-1207. Epub 03/30/2018.

Presurgical depression and anxiety are not associated with worse epilepsy surgery outcome five years postoperatively.

Altalib HH, Berg AT, Cong X, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Bazil CW, Sukumar N, Devinsky O

Epilepsy & behavior : E&B.. 2018 June 83 :7-12. Epub 04/07/2018.

A complete list of Dr. Langfitt's peer reviewed publications can be found by clicking on the link.

2017; .

Cognition, behavior, and the ILAE Classification of the Epilepsies: A view from Africa.

Langfitt JT

Epilepsy & behavior : E&B.. 2016 November 64 (Pt B):311-312. Epub 05/10/2016.

Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery.

Hamid H, Blackmon K, Cong X, Dziura J, Atlas LY, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Devinsky O

Neurology.. 2014 March 1182 (10):887-94. Epub 01/31/2014.

Influence of anxiety on memory performance in temporal lobe epilepsy.

Brown FC, Westerveld M, Langfitt JT, Hamberger M, Hamid H, Shinnar S, Sperling MR, Devinsky O, Barr W, Tracy J, Masur D, Bazil CW, Spencer SS

Epilepsy & behavior : E&B.. 2014 February 31 :19-24. Epub 11/26/2013.

Homotopic language reorganization in the right hemisphere after early left hemisphere injury.

Tivarus ME, Starling SJ, Newport EL, Langfitt JT

Brain and language.. 2012 October 123 (1):1-10. Epub 07/24/2012.

Web-based eight-question tool to determine epilepsy surgery evaluation: the future is here.

Langfitt JT, Mathern GW

Neurology.. 2012 September 1179 (11):1074-5. Epub 08/15/2012.

Treatment of refractory mesial temporal lobe epilepsy-reply.

Engel J, McDermott MP, Langfitt JT

JAMA.. 2012 June 20307 (23):2483-5. Epub 1900 01 01.

Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial.

Engel J, McDermott MP, Wiebe S, Langfitt JT, Stern JM, Dewar S, Sperling MR, Gardiner I, Erba G, Fried I, Jacobs M, Vinters HV, Mintzer S, Kieburtz K,

JAMA.. 2012 March 7307 (9):922-30. Epub 1900 01 01.

Homotopic Language Reorganization in the Right Hemisphere after Early Left Hemisphere Injury

Tivarus, ME;Starling, SJ;Newport, EL; Langfitt, JT.

Brain and Language. 2012; .

Suicide outcomes after resective epilepsy surgery.

Hamid H, Devinsky O, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS

Epilepsy & behavior : E&B.. 2011 March 20 (3):462-4. Epub 02/19/2011.

Mapping anterior temporal lobe language areas with fMRI: a multicenter normative study.

Binder JR, Gross WL, Allendorfer JB, Bonilha L, Chapin J, Edwards JC, Grabowski TJ, Langfitt JT, Loring DW, Lowe MJ, Koenig K, Morgan PS, Ojemann JG, Rorden C, Szaflarski JP, Tivarus ME, Weaver KE

NeuroImage.. 2011 January 1554 (2):1465-75. Epub 09/25/2010.

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy.

Engel J, McDermott MP, Wiebe S, Langfitt JT, Erba G, Gardiner I, Stern J, Dewar S, Sperling MR, Jacobs M, Kieburtz K,

Epilepsia.. 2010 October 51 (10):1978-86. Epub 1900 01 01.

Design considerations for a multicenter randomized controlled trial of early surgery for mesial temporal lobe epilepsy

Engel, J, Jr.;McDermott, MP;Wiebe, S; Langfitt JT;Erba, G; Gardiner, I; Stern, J; Dewar, S; Sperling, M; Jacobs, M; Kieburtz, K; and the ERSET Study Group.

Epilepsia. 2010; 51(10): 1978-1986.

Mapping Anterior Temporal Lobe Language Areas with FMRI: A Multi-Center Normative Study

Binder, JB; Gross, WL; Allendorfer, JB; Bonilha, L; Chapin, J; Edwards, JC; Grabowski, TJ; Langfitt, JT; Loring, DW; Lowe, MJ; Koenig, K; Morgan, PS; Ojemann, JG; Rorden, C; Szaflarski, JP; Tivarus, ME; Weaver, KE.

NeuroImage. 2010; 54(2): 1465-1475.

Residual cognitive effects of uncomplicated idiopathic and cryptogenic epilepsy.

Berg AT, Langfitt JT, Testa FM, Levy SR, DiMario F, Westerveld M, Kulas J

Epilepsy & behavior : E&B.. 2008 November 13 (4):614-9. Epub 08/19/2008.

Global cognitive function in children with epilepsy: a community-based study.

Berg AT, Langfitt JT, Testa FM, Levy SR, DiMario F, Westerveld M, Kulas J

Epilepsia.. 2008 April 49 (4):608-14. Epub 12/06/2007.

Early surgical treatment for epilepsy.

Langfitt JT, Wiebe S

Current opinion in neurology.. 2008 April 21 (2):179-83. Epub 1900 01 01.

Residual cognitive effects of uncomplicated idiopathic and cryptogenic epilepsy.

Berg, AT; Langfitt, JT;T esta FM; Levy SR; Dimario F; Westerveld M; Kulas J.

Epilepsy and Behavior. 2008; 13: 614-619.

Global Cognitive Function in Children with Epilepsy: A community-based study

Berg, AT; Langfitt, JT; Testa FM; Levy SR; Dimario F; Westerveld M; Kulas J.

Epilepsia. 2008; 49(4): 608-14.

Employment outcomes following resective epilepsy surgery.

Chin PS, Berg AT, Spencer SS, Sperling MR, Haut SR, Langfitt JT, Bazil CW, Walczak TS, Pacia SV, Vickrey BG

Epilepsia.. 2007 December 48 (12):2253-7. Epub 07/21/2007.

Do we know quality epilepsy care when we see it?

Langfitt JT

Neurology.. 2007 November 2069 (21):1968-9. Epub 1900 01 01.

Health-related quality of life over time since resective epilepsy surgery.

Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Haut S, Langfitt JT, Walczak TS, Devinsky O,

Annals of neurology.. 2007 October 62 (4):327-34. Epub 1900 01 01.

Worsening of quality of life after epilepsy surgery: effect of seizures and memory decline.

Langfitt JT, Westerveld M, Hamberger MJ, Walczak TS, Cicchetti DV, Berg AT, Vickrey BG, Barr WB, Sperling MR, Masur D, Spencer SS

Neurology.. 2007 June 568 (23):1988-94. Epub 1900 01 01.

Cross-country measures for monitoring epilepsy care.

Begley CE, Baker GA, Beghi E, Butler J, Chisholm D, Langfitt JT, Levy P, Pachlatko C, Wiebe S, Donaldson KL,

Epilepsia.. 2007 May 48 (5):990-1001. Epub 02/23/2007.

Health care costs decline after successful epilepsy surgery.

Langfitt JT, Holloway RG, McDermott MP, Messing S, Sarosky K, Berg AT, Spencer SS, Vickrey BG, Sperling MR, Bazil CW, Shinnar S

Neurology.. 2007 April 1768 (16):1290-8. Epub 1900 01 01.

Stopping antiepileptic drugs after epilepsy surgery: a survey of U.S. epilepsy center neurologists.

Berg AT, Langfitt JT, Spencer SS, Vickrey BG

Epilepsy & behavior : E&B.. 2007 March 10 (2):219-22. Epub 01/23/2007.

Stopping Antiepileptic Drugs After Epilepsy Surgery: A Survey of US Epilepsy Center Neurologists.

Berg, AT; Langfitt, JT; Vickrey, BG; Spencer, SS.

Epilepsy & Behavior. 2007; 10:: 219-222.

Epilepsy in North America: a report prepared under the auspices of the global campaign against epilepsy, the International Bureau for Epilepsy, the International League Against Epilepsy, and the World Health Organization.

Theodore WH, Spencer SS, Wiebe S, Langfitt JT, Ali A, Shafer PO, Berg AT, Vickrey BG

Epilepsia.. 2006 October 47 (10):1700-22. Epub 1900 01 01.

Patient-perceived impact of resective epilepsy surgery.

Chin PS, Berg AT, Spencer SS, Lee ML, Shinnar S, Sperling MR, Langfitt JT, Walczak TS, Pacia SV, Bazil CW, Vassar S, Vickrey BG

Neurology.. 2006 June 2766 (12):1882-7. Epub 1900 01 01.

Validity and responsiveness of generic preference-based HRQOL instruments in chronic epilepsy.

Langfitt JT, Vickrey BG, McDermott MP, Messing S, Berg AT, Spencer SS, Sperling MR, Bazil CW, Shinnar S

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation.. 2006 June 15 (5):899-914. Epub 1900 01 01.

Reduction of AEDs in postsurgical patients who attain remission.

Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Shinnar S, Bazil C, Walczak T, Spencer SS,

Epilepsia.. 2006 January 47 (1):64-71. Epub 1900 01 01.

Changes in depression and anxiety after resective surgery for epilepsy.

Devinsky O, Barr WB, Vickrey BG, Berg AT, Bazil CW, Pacia SV, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Spencer SS

Neurology.. 2005 December 1365 (11):1744-9. Epub 1900 01 01.

Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study.

Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV,

Neurology.. 2005 September 2765 (6):912-8. Epub 1900 01 01.

Preserved episodic memory in subcortical band heterotopia.

Janzen L, Sherman E, Langfitt J, Berg M, Connolly M

Epilepsia.. 2004 May 45 (5):555-8. Epub 1900 01 01.

Initial outcomes in the Multicenter Study of Epilepsy Surgery.

Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Shinnar S, Langfitt JT, Walczak TS, Pacia SV, Ebrahimi N, Frobish D,

Neurology.. 2003 December 2361 (12):1680-5. Epub 1900 01 01.

The multicenter study of epilepsy surgery: recruitment and selection for surgery.

Berg AT, Vickrey BG, Langfitt JT, Sperling MR, Walczak TS, Shinnar S, Bazil CW, Pacia SV, Spencer SS,

Epilepsia.. 2003 November 44 (11):1425-33. Epub 1900 01 01.

Predicting verbal memory decline following anterior temporal lobectomy (ATL).

Stroup E, Langfitt J, Berg M, McDermott M, Pilcher W, Como P

Neurology.. 2003 April 2260 (8):1266-73. Epub 1900 01 01.

How long does it take for partial epilepsy to become intractable?

Berg AT, Langfitt J, Shinnar S, Vickrey BG, Sperling MR, Walczak T, Bazil C, Pacia SV, Spencer SS

Neurology.. 2003 January 2860 (2):186-90. Epub 1900 01 01.

Interrater reliability among epilepsy centers: multicenter study of epilepsy surgery.

Haut SR, Berg AT, Shinnar S, Cohen HW, Bazil CW, Sperling MR, Langfitt JT, Pacia SV, Walczak TS, Spencer SS

Epilepsia.. 2002 November 43 (11):1396-401. Epub 1900 01 01.

ILAE Commission on the Burden of Epilepsy, Subcommission on the Economic Burden of Epilepsy: Final report 1998-2001.

Begley CE, Beghi E, Beran RG, Heaney D, Langfitt JT, Pachlatko C, Silfvenius H, Sperling MR, Wiebe S

Epilepsia.. 2002 June 43 (6):668-73. Epub 1900 01 01.

Cost-effectiveness of epilepsy therapy: how should treatment effects be measured?

Langfitt J ; Wiebe S.

Epilepsia. 2002; (Suppl. 4): 17-24.

Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy.

Vickrey BG, Berg AT, Sperling MR, Shinnar S, Langfitt JT, Bazil CW, Walczak TS, Pacia S, Kim S, Spencer SS

Epilepsia.. 2000 June 41 (6):760-4. Epub 1900 01 01.

Driving in adults with refractory localization-related epilepsy. Multi-Center Study of Epilepsy Surgery.

Berg AT, Vickrey BG, Sperling MR, Langfitt JT, Bazil CW, Shinnar S, Walczak TS, Pacia S, Spencer SS

Neurology.. 2000 February 854 (3):625-30. Epub 1900 01 01.

Cost evaluations in epilepsy: an update.

Langfitt, JT.

Epilepsia. 2000; 41(S2): S62-68.

Family interactions as targets for intervention to improve social adjustment after epilepsy surgery.

Langfitt JT, Wood BL, Brand KL, Brand J, Erba G

Epilepsia.. 1999 June 40 (6):735-44. Epub 1900 01 01.

Use of surgical procedures in the treatment of epilepsy: interventions and outcomes. Disease Management &

Langfitt, JT; Bronstein, K.

Health Outcomes. 1999; 5:: 23-40.

Cost-effectiveness of anterotemporal lobectomy in medically intractable complex partial epilepsy.

Langfitt JT

Epilepsia.. 1997 February 38 (2):154-63. Epub 1900 01 01.

Analysis of outcome: temporal lobe resection.

Pilcher WH, Langfitt J

Clinical neurosurgery. 1997 44 :401-21. Epub 1900 01 01.

Word-finding deficits persist after left anterotemporal lobectomy.

Langfitt JT, Rausch R

Archives of neurology.. 1996 January 53 (1):72-6. Epub 1900 01 01.

Comparison of the psychometric characteristics of three quality of life measures in intractable epilepsy.

Langfitt JT

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation.. 1995 April 4 (2):101-14. Epub 1900 01 01.

Prosopagnosia: a bihemispheric disorder.

Ettlin TM, Beckson M, Benson DF, Langfitt JT, Amos EC & Pineda GS.

Cortex. 1992; 28(1):: 128-134.

Books

In response: Towards a quantitative assessment of psychogenic nonepileptic seizures. (2016)

Cognition, behavior, and the ILAE Classification of the Epilepsies: (2016)

Chapter: A view from Africa. Epilepsy Behav.

In response: Towards a quantitative assessment of psychogenic nonepileptic seizures. (2016)

Chapter: (https://www.ncbi.nlm.nih.gov/pubmed/27286757) Epilepsia.

Evaluation and Management of Psychogenic, Non-epileptic Attacks. In Barr, W & Morrison, C (2014)

Chapter: Handbook of the Neuropsychology of Epilepsy.

Handbook of the Neuropsychology of Epilepsy. (2013)

Chapter: Evaluation and Management of Psychogenic, Non-epileptic Attacks

The future is here: Web-based eight-question tool to determine epilepsy surgery evaluation (2012)

Atlas of the Epilepsies (2010)

Chapter: Cognition

"Cognition". (2010)

Chapter: Atlas of the Epilepsies. Panayiotopoulos, CP.

"Seizures" or Attacks" (2010)

Chapter: a follow-up (editorial).

Forgetting to remember in epilepsy: a family affair? (2010)

Sperling MR. Intracarotid amobarbital procedure for epilepsy surgery. (2010)

Chapter: (http://www.ncbi.nlm.nih.gov/pubmed/21190900)

Epilepsy: A Comprehensive Textbook: 2nd Edition. (2008)

Chapter: Economic aspects of epilepsy and antiepileptic treatment.

Epilepsy: A Comprehensive Textbook: 2nd Edition. (2008)

Chapter: Outcome Measures.

Outcome Measures. In Engel J Jr. and Pedley TA, (eds.). (2008)

Chapter: Epilepsy: A Comprehensive Textbook: 2nd Edition.

Economic aspects of epilepsy and antiepileptic treatment. (2008)

Chapter: In Engel J Jr. and Pedley TA, (eds.). Epilepsy: A Comprehensive Textbook: 2nd Edition.

"Do we know quality epilepsy care when we see it?" (2007)

Want to improve epilepsy care? Ask the patient (2004)

Cost-effectiveness of epilepsy therapy: how should treatment effects be measured? (2002)

Chapter: Epilepsia 43

Prognosis of Neurological Disorders, (2nd ed.) (2000)

Chapter: Economic prognosis: evaluating the economic outcomes of health care.

Cost evaluations in epilepsy: an update. (2000)

Chapter: Epilepsia 41(S2)

Economic prognosis: evaluating the economic outcomes of health care. (2000)

Chapter: In Evans, RW, Baskin, DS & Yatsu, FM (eds.) Prognosis of Neurological Disorders,(2nd ed).

Use of surgical procedures in the treatment of epilepsy: interventions and outcomes. (1999)

Chapter: Disease Management & Health Outcomes 5:

(2002) ILAE commission on the burden of epilepsy, subcommission on the economic burden of epilepsy: final report 1998-2001. (1998)

Epilepsy A Comprehensive Textbook (1997)

Chapter: Neuropsychological Evaluation - Adults. In Engel J Jr. and Pedley TA (eds.)

Economic evaluation of health care: relevance to epilepsy care in the 1990s (1997)

Neuropsychological Evaluation - Adults. In Engel J Jr. and Pedley TA (eds.), (1997)

Chapter: Epilepsy: A Comprehensive Textbook

Surgery for Epilepsy (1991)

Chapter: Memory Evaluation during the Intracarotid Sodium Amobarbital Procedure.

Rausch R & Langfitt JT. Memory Evaluation during the Intracarotid Sodium Amobarbital Procedure (1991)

Chapter: Surgery for Epilepsy