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Dina G. Markowitz, Ph.D.

Dina G. Markowitz, Ph.D.

Connect with Dina G. Markowitz, Ph.D.

Life Sciences Learning Center

About Me

Faculty Appointments

Professor - Department of Environmental Medicine (SMD)

Professor - Center for Community Health and Prevention - Joint

Credentials

Post-doctoral Training & Residency

University of Rochester, Post-doctoral teaching fellowship, Department of Microbiology and Immunology 1995 - 1998

SmithKline Beecham Corporation, Post-doctoral fellowship. Mentor: Mitchell Gross, Ph.D. 1990 - 1991

Veterinary Hospital of the University of Pennsylvania, Post-doctoral fellowship. Mentor: John Wolfe, V.M.D., Ph.D. 1989 - 1990

Education

PhD | Columbia University. Genetics. 1989

M. Phil. | Columbia University. Genetics and Development. 1987

M.A. | Columbia University. Genetics and Development. 1985

BA | Brandeis University. Biology. 1984

Awards

Provisional Patent application 61057002. 2008

UR Medical Center License Agreement #AGR-0253. 2006

Children's Environmental Health Recognition Award. 2005

Retroviral Packaging Cell Lines. 1994

Sigma XI Scientific Research Honor Society. 1988

Research

As Director of the University of Rochester's Life Sciences Learning Center (LSLC), I am responsible for developing and coordinating a wide variety of science education and outreach programs for students (elementary through high school), teachers, and the general community. LSLC programs emphasize ha...
As Director of the University of Rochester's Life Sciences Learning Center (LSLC), I am responsible for developing and coordinating a wide variety of science education and outreach programs for students (elementary through high school), teachers, and the general community. LSLC programs emphasize hands-on and minds-on learning to boost science literacy and increase enthusiasm towards learning science. These programs include field trips to our LSLC teaching lab, in-school programs, science camps and clubs, community programs, and science teacher workshops.

I have led numerous science education projects that have involved curriculum development and teacher professional development on a wide variety of topics such environmental health, genetic testing, stem cells, neuroscience, nanoparticles, kidney disease, drug abuse and addiction, cancer, and health literacy. These projects have brought engaging, hands-on and minds-on curriculum materials to teachers and their students throughout the US.

This includes teaching opportunities at the LSLC and various courses and workshops that I have taught on science education and science communication.

Patents

LSLC Virtual Laboratory: Genetic Testing for Huntington's Disease

Issue date: August 04, 2006

Patent #: TX 6-439-169

Country: United States

Inventors: Shaw-Ree Chen, Michael DuPre, Susan W Holt, Dina G Markowitz

Bioterrorism in Western New York

Issue date: August 04, 2006

Patent #: TX 6-439-168

Country: United States

Inventors: Shaw-Ree Chen, Dina G Markowitz

LSLC Breakout

Issue date: August 04, 2006

Patent #: TX 6-424-852

Country: United States

Inventors: Shaw-Ree Chen, Kimberly LaCelle, Dina G Markowitz

Science fair Experiment: How to get started

Issue date: August 04, 2006

Patent #: TX 6-439-554

Country: United States

Inventors: Amanda Genaux, Dina G Markowitz, Christina Sutton

Kidney Donor

Issue date: October 20, 2008

Patent #: TXu 1-591-668

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Kidney Dialysis

Issue date: October 20, 2008

Patent #: TXu001591685

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Stem Cells

Issue date: December 16, 2009

Patent #: TXu 1-660-550

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Is FLORATRYP Addicting?

Issue date: October 30, 2012

Patent #: TXu 1-836-011

Country: United States

Inventors: Shaw-Ree Chen, Susan W Holt, Dina G Markowitz

Hand on a Hot Stove - Teacher version

Issue date: January 14, 2014

Patent #: TXu 1-899-665

Country: United States

Inventors: Shaw-Ree Chen, Susan W Holt, Dina G Markowitz

Hand on a Hot Stove - Student version

Issue date: January 14, 2014

Patent #: TXu 1-899-666

Country: United States

Inventors: Shaw-Ree Chen, Susan W Holt, Dina G Markowitz

Disease Detectives - Teacher version

Issue date: January 14, 2014

Patent #: TXu 1-899-663

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Disease Detectives - Student version

Issue date: January 14, 2014

Patent #: TXu 1-899-664

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Taste Blind

Issue date: March 12, 2015

Patent #: TXu 1-952-209

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

A Bang to the Head

Issue date: April 07, 2016

Patent #: TXu 2-010-896

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

A Case of Unintentional Overdose

Issue date: November 19, 2018

Patent #: TXu 2-124-832

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Cold, Flu or Allergy?

Issue date: November 19, 2018

Patent #: TXu 2-124-828

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Developing a New Flu Prevention Drug

Issue date: November 19, 2018

Patent #: TXu 2-124-829

Country: United States

Inventors: Susan W Holt, Dina G Markowitz

Publications

Journal Articles

Social Determinants of Health in Idiopathic Intracranial Hypertension.

Markowitz D, Aamodt WW, Hamedani AG

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society.. 2024 September 144 (3):346-349. Epub 01/03/2024.

Identifying breast cancer recurrence histories via patient-reported outcomes.

Beatty JD, Sun Q, Markowitz D, Chubak J, Huang B, Etzioni R

Journal of cancer survivorship : research and practice.. 2022 April 16 (2):388-396. Epub 04/14/2021.

Type II Achalasia Is Increasing in Prevalence.

Zhou MJ, Kamal A, Freedberg DE, Markowitz D, Clarke JO, Jodorkovsky D

Digestive diseases and sciences.. 2021 October 66 (10):3490-3494. Epub 10/22/2020.

Phase II Multicenter, Open-Label Study of Oral ENMD-2076 for the Treatment of Patients with Advanced Fibrolamellar Carcinoma.

Abou-Alfa GK, Mayer R, Venook AP, O'Neill AF, Beg MS, LaQuaglia M, Kingham PT, Kobos R, Basturk O, Brennan C, Yopp A, Harding JJ, Leong S, Crown J, Hoti E, Leonard G, Ly M, Bradley M, Valentino E, Markowitz D, Zukiwski A, Ren K, Gordan JD

The oncologist.. 2020 December 25 (12):e1837-e1845. Epub 03/10/2020.

Correction: Incorporating Breast Cancer Recurrence Events Into Population-Based Cancer Registries Using Medical Claims: Cohort Study.

A'mar T, Beatty JD, Fedorenko C, Markowitz D, Corey T, Lange J, Schwartz SM, Huang B, Chubak J, Etzioni R

JMIR cancer.. 2020 September 246 (2):e23821. Epub 09/24/2020.

Incorporating Breast Cancer Recurrence Events Into Population-Based Cancer Registries Using Medical Claims: Cohort Study.

A'mar T, Beatty JD, Fedorenko C, Markowitz D, Corey T, Lange J, Schwartz SM, Huang B, Chubak J, Etzioni R

JMIR cancer.. 2020 August 176 (2):e18143. Epub 08/17/2020.

Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors.

De Witt M, Gamble A, Hanson D, Markowitz D, Powell C, Al Dimassi S, Atlas M, Boockvar J, Ruggieri R, Symons M

Molecular medicine.. 2017 April 23 :50-56. Epub 04/05/2017.

Compact Intraoperative MRI: Stereotactic Accuracy and Future Directions.

Markowitz D, Lin D, Salas S, Kohn N, Schulder M

Stereotactic and functional neurosurgery.. 2017 95 (3):197-204. Epub 06/15/2017.

Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma.

Markowitz D, Powell C, Tran NL, Berens ME, Ryken TC, Vanan M, Rosen L, He M, Sun S, Symons M, Al-Abed Y, Ruggieri R

Molecular cancer therapeutics.. 2016 August 15 (8):1799-808. Epub 05/20/2016.

Simulating Science: Manipulative models and small scale simulations that promote learning of complex biological concepts.

Markowitz, D.; Holt, S.

The Science Teacher. 2011; : 44-48.

Contradictions in educational policy: Implementing integrated problem-based curriculum in a high stakes environment.

Martina, C.; Hursh, D.; Markowitz, D.

Environmental Education Research. 2009; 15(3): 279-281.

BEGIN Partnership: Using Problem-Based Learning to Teach Genetics and Bioethics.

Markowitz, D.; DuPre, M.; Holt, S.; Chen, S.; Wischnowski, M.

American Biology Teacher. 2008; 70(7): 421-425.

Science Teachers' Perceived Benefits of an Out-of-School Enrichment Programme: Identity Needs and University Affordances.

Luehmann, A.; Markowitz, D.

International Journal of Science Education. 2007; 29(9): 1133-1161.

Graduate Experience in Science Education: the development of a science education course for biomedical science graduate students.

Markowitz DG, DuPré MJ

CBE life sciences education.. 2007 6 (3):233-42. Epub 1900 01 01.

Family Secrets: The Bioethics of Genetic Testing.

Markowitz, D.; DuPre, M.; Holt, S.; Chen, S.; Wischnowski, M.

The Science Teacher. 2006; 73(8): 28-32.

Evaluation of the long-term impact of a university high school summer science program on students' interest and perceived abilities in science.

Markowitz, D.

J. Science Education and Technology. 2004; 13(3): 395-407.

Evaluation of short-term impact of a high school summer science program on students' perceived knowledge and skills.

Knox, K.; Moynihan, J.; Markowitz, D.

J. Science Education and Technology. 2003; 12(4): 471-478.

High level expression and export of beta-glucuronidase from murine mucopolysaccharidosis VII cells corrected by a double-copy retrovirus vector.

Wolfe JH, Kyle JW, Sands MS, Sly WS, Markowitz DG, Parente MK

Gene therapy.. 1995 January 2 (1):70-8. Epub 1900 01 01.

Somatic gene therapy.

Hesdorffer C, Markowitz D, Ward M, Bank A

Hematology/oncology clinics of North America.. 1991 June 5 (3):423-32. Epub 1900 01 01.

Gene transfer of adenosine deaminase into primitive human hematopoietic progenitor cells.

Cournoyer D, Scarpa M, Mitani K, Moore KA, Markowitz D, Bank A, Belmont JW, Caskey CT

Human gene therapy.. 1991 2 (3):203-13. Epub 1900 01 01.

Efficient gene transfer in live mice using a unique retroviral packaging line.

Hesdorffer C, Ward M, Markowitz D, Bank A

DNA and cell biology.. 1990 December 9 (10):717-23. Epub 1900 01 01.

Retroviral gene transfer using safe and efficient packaging cell lines.

Markowitz D, Hesdorffer C, Ward M, Goff S, Bank A

Annals of the New York Academy of Sciences.. 1990 612 :407-14. Epub 1900 01 01.

Retroviral gene transfer in mice: the use of a unique packaging line improves efficiency.

Hesdorffer CS, Markowitz D, Ward M, Lerner NB, Bank A

Advances in experimental medicine and biology.. 1989 271 :149-60. Epub 1900 01 01.

Gene transfer. A potential approach to gene therapy for sickle cell disease.

Bank A, Markowitz D, Lerner N

Annals of the New York Academy of Sciences.. 1989 565 :37-43. Epub 1900 01 01.

Construction and use of a safe and efficient amphotropic packaging cell line.

Markowitz D, Goff S, Bank A

Virology.. 1988 December 167 (2):400-6. Epub 1900 01 01.

A safe packaging line for gene transfer: separating viral genes on two different plasmids.

Markowitz D, Goff S, Bank A

Journal of virology.. 1988 April 62 (4):1120-4. Epub 1900 01 01.

Construction of a safe and efficient retrovirus packaging cell line.

Markowitz D, Goff S, Bank A

Advances in experimental medicine and biology.. 1988 241 :35-40. Epub 1900 01 01.

Expression of chimeric human beta- and delta-globin genes during erythroid differentiation.

LaFlamme S, Acuto S, Markowitz D, Vick L, Landschultz W, Bank A

The Journal of biological chemistry.. 1987 April 5262 (10):4819-26. Epub 1900 01 01.

Mutant alleles at the locus elav in Drosophila melanogaster lead to nervous system defects. A developmental-genetic analysis.

Campos A.R.; Grossman D.; White K.

J. Neurogen. 1985; 2: 197.

Books

Molecular Biology of Erythropoiesis (1990)

Chapter: Retroviral gene transfer in mice: The use of a unique packaging line improves efficiency

Authors: Hesdorffer, C.S.; Markowitz, D.; Ward, M.; Lerner, N.B.; Bank, A

Publisher: Plenum Press, New York 1990

Sixth Cooley's Anemia Symposium (1990)

Chapter: Retroviral gene transfer using safe and efficient packaging cell lines

Authors: Markowitz, D.; Hesdorffer, C.; Ward, M.; Goff, S.; Bank, A

Publisher: Ann. N.Y. Acad. Sci., New York 1990

Hematology/Oncology Clinics of North America (1990)

Chapter: Somatic gene therapy

Authors: Hesdorffer, C.; Markowitz, D.; Ward, M.; Bank, A

Publisher: WB Saunders Company, New York 1990

Sickle Cell Disease - Current Perspectives (1989)

Chapter: Gene transfer experimentation: A potential approach to gene transfer for sickle cell disease

Authors: Bank, A.; Markowitz, D.; Lerner, N

Publisher: Current Perspectives, New York 1989

Molecular Biology of Hemopoiesis (1988)

Chapter: Construction of a safe and efficient retrovirus packaging cell line

Authors: Markowitz, D.; Goff, S.; Bank, A

Publisher: Plenum Press, New York 1988