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Krystel Huxlin, Ph.D.

Krystel Huxlin, Ph.D.

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Office (585) 275-5495
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About Me

Dr. Krystel Huxlin is the James V. Aquavella Professor of Ophthalmology and Director of Research in the Department of Ophthalmology and Flaum Eye Institute at the University of Rochester, Rochester, NY, USA. She also serves as the Associate Director of the Center for Visual Science and co-Director o...
Dr. Krystel Huxlin is the James V. Aquavella Professor of Ophthalmology and Director of Research in the Department of Ophthalmology and Flaum Eye Institute at the University of Rochester, Rochester, NY, USA. She also serves as the Associate Director of the Center for Visual Science and co-Director of its Training program. Finally, she serves as an SMD Ombudsperson for Graduate Students, Postdoctoral Appointees, and Preparatory Program Trainees. Aside from her primary appointment in Ophthalmology, she holds secondary appointments in the Center for Visual Science, the Institute of Optics, the Departments of Neuroscience and Brain & Cognitive Sciences at the University of Rochester. Dr. Huxlin earned her bachelor’s of medical science (1991) and doctorate in neuroscience (1994) at the University of Sydney, Australia, before joining the Ophthalmology faculty at the University of Rochester (1999). Her work seeks to understand how visual functions can be restored after damage. An author on more than 90 peer-reviewed publications and book chapters, she holds 11 patents. Among her many project, she studied molecular substrates of corneal wound healing with the goal of preventing or treating scarring and restoring optical quality after insults to the ocular surface. She is also part of the team that developed LIRIC, a novel, non-surgical paradigm for laser refractive error correction. Most of her current efforts are focused on understanding neuroplasticity in the damaged, adult visual system, with an eye towards vision restoration (see description of current Research below). She was the founder and inaugural President of the Rochester Chapter of the Society for Neuroscience. She is also an elected Fellow of Optica, and a member of the Board of Directors of the Vision Sciences Society, for whom she currently serves as President-elect. Finally, in additional to her service as a reviewer for granting bodies world-wide, she serves on the Board of Reviewing Editors at eLife and the Journal of Vision.

Faculty Appointments

Professor - Department of Ophthalmology (SMD)

Professor - Department of Brain/Cognitive Sciences RC (RC) - Joint

Professor - Center for Visual Science A&S (RC) - Joint

Professor - Department of Neuroscience (SMD) - Joint

Director of Research - Department of Ophthalmology (SMD) - Joint

Professor - Department of The Institute for Optics (RC) - Joint

Credentials

Education

PhD | Australia-U Sydney Fac Med. Neuroscience. 1994

BS | Australia-U Sydney Fac Med. Neuroscience. 1991

Research

How does the adult visual system repair itself after damage? To what extent can it do so? What are the principles governing such plasticity? How can knowledge we gain enhance vision restoration efforts? The Visual Perceptual Restoration Laboratory (VisPeR Lab) studies the impact of visual system da...
How does the adult visual system repair itself after damage? To what extent can it do so? What are the principles governing such plasticity? How can knowledge we gain enhance vision restoration efforts? The Visual Perceptual Restoration Laboratory (VisPeR Lab) studies the impact of visual system damage on behavior and seeks to develop new approaches to induce visual restoration after such damage. For the last few decades, our laboratory has been at the forefront of research into cortically-induced blindness, applying the knowledge we gain to devise increasingly effective training paradigms for occipital stroke patients (a.k.a. those with hemianopia, quadrantanopia or cerebral visual impairment). Key to this effort is our ability to use perceptual training together with attentional manipulations, cross-modal cues, virtual reality, non-invasive, transcranial electrical stimulation - among other approaches - to restore some of the vision lost. We were the first to attempt visual restoration training in subacute stroke patients – the efficacy of which is currently being evaluated in a clinical trial (ClinicalTrials.gov # NCT04798924). Ongoing projects include both in-house and collaborative work with colleagues at the University of Rochester and key institutions nationally and internationally. Overall, we seek deeper insights into how residual visual circuitry is altered both by cortical damage and training. Better characterization of the perceptual plasticity inherent in such damaged systems is essential to design more effective restorative treatments. Ultimately, the principles of therapeutic design applied to cortically-induced blindness may also prove beneficial for other forms of visual impairment that afflict patients world-wide.

Clinical Trials

The Impact of Vision Loss on Naturalistic Behavior and Navigation in Virtual Reality,The Impact of Vision Loss on Naturalistic Behavior and Navigation in Virtual Reality

Lead Researcher: Krystel Huxlin

Stroke is the main cause of damage to the part of the brain that processes visual information from the eyes. This can lead to vision loss even when there is no damage to the eyes. The purpose of this research is to better understand how people compen...

Visual Rehabilitation After Occipital Stroke

Lead Researcher: Krystel Huxlin

We will measure structural and mechanistic aspects of progressive degeneration along the early visual pathways, correlating them with changes in visual performance, and in responsiveness to visual restoration training. This project will advance both ...

Patents

Systems and Methods for Improving Visual Discrimination

Issue date: June 23, 2009

Patent #: 7,549,743

Country: United States

Inventors: Mary Hayhoe, Krystel R Huxlin, Jeff B Pelz

Multi-Photon Absorption for Femtosecond Micromachining and Refractive Index Modification of Tissues

Issue date: January 17, 2017

Patent #: 9,545,340

Country: United States

Inventors: Li Ding, Krystel R Huxlin, Wayne H Knox

Method for Modifying the Refractive Index of Ocular Tissues

Issue date: July 16, 2013

Patent #: 8,486,055

Country: United States

Inventors: Li Ding, Krystel R Huxlin, Wayne H Knox, Jay F Kunzler

Method for Modifying the Refractive Index of Ocular Tissues

Issue date: December 31, 2013

Patent #: 8,617,147

Country: United States

Inventors: Krystel R Huxlin, Wayne H Knox

Method for Modifying the Refractive Index of Ocular Tissues and Applications Thereof

Issue date: October 27, 2020

Patent #: 10,813,791

Country: United States

Inventors: Krystel R Huxlin, Wayne H Knox

Method for Modifying the Refractive Index of Ocular Tissues

Issue date: August 20, 2013

Patent #: 8,512,320

Country: United States

Inventors: Li Ding, Krystel R Huxlin, Wayne H Knox, Jay F Kunzler

Method for Modifying the Refractive Index of Ocular Tissues

Issue date: November 15, 2016

Patent #: 9,492,323

Country: United States

Inventors: Krystel R Huxlin, Wayne H Knox

Multi-Photon Absorption for Femtosecond Micromachining and Refractive Index Modification of Tissues

Issue date: March 12, 2019

Patent #: 10,226,381

Country: United States

Inventors: Li Ding, Krystel R Huxlin, Wayne H Knox

Method for Modifying the Refractive Index of Ocular Tissues

Issue date: April 30, 2019

Patent #: 10,271,991

Country: United States

Inventors: Krystel R Huxlin, Wayne H Knox

Publications

Journal Articles

Optic flow density modulates corner-cutting in a virtual steering task for younger and older adults.

Giguere AP, Huxlin KR, Tadin D, Fajen BR, Diaz GJ

Scientific reports.. 2024 November 1214 (1):27693. Epub 11/12/2024.

MAIA and Humphrey Perimetry Differ in Their Estimation of Homonymous Visual Field Defects.

Redmond BV, Fahrenthold BK, Yang J, Saionz EL, Cavanaugh MR, Huxlin KR

Translational vision science & technology.. 2024 November 413 (11):15. Epub 1900 01 01.

Multiphoton scaling of femtosecond laser-induced refractive index change (LIRIC) in hydrogels and rabbit cornea.

Wozniak KT, Manning ZA, Huang R, Cox S, Butler SC, Ferlo S, Zheleznyak L, Xu L, Ellis JD, Huxlin KR, Knox WH

Biomedical optics express.. 2024 November 115 (11):6242-6258. Epub 10/08/2024.

Persistence of training-induced visual improvements after occipital stroke.

Willis HE, Farenthold B, Millington-Truby RS, Willis R, Starling L, Cavanaugh M, Tamietto M, Huxlin K, Bridge H

medRxiv : the preprint server for health sciences.. 2024 October 24 Epub 10/24/2024.

Manipulating mitochondrial pyruvate carrier function causes metabolic remodeling in corneal myofibroblasts that ameliorates fibrosis.

Jeon KI, Kumar A, Brookes PS, Nehrke K, Huxlin KR

Redox biology.. 2024 September 75 :103235. Epub 06/08/2024.

Vision-related quality of life after unilateral occipital stroke.

Dogra N, Redmond BV, Lilley S, Johnson BA, Lam BL, Tamhankar M, Feldon SE, Fahrenthold B, Yang J, Huxlin KR, Cavanaugh MR

Brain and behavior.. 2024 July 14 (7):e3582. Epub 1900 01 01.

Training in Cortically Blinded Fields Appears to Confer Patient-Specific Benefit Against Retinal Thinning.

Fahrenthold BK, Cavanaugh MR, Tamhankar M, Lam BL, Feldon SE, Johnson BA, Huxlin KR

Investigative ophthalmology & visual science.. 2024 April 165 (4):29. Epub 1900 01 01.

Limited restoration of contrast sensitivity with training after V1 damage in humans.

Yang ??? J, Saionz EL, Cavanaugh MR, Fahrenthold BK, Melnick MD, Tadin D, Briggs F, Carrasco M, Huxlin KR

eNeuro.. 2024 February 2311 (3)Epub 02/23/2024.

Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 1 registered report.

Willis HE, Cavanaugh MR, Ajina S, Pestilli F, Tamietto M, Huxlin KR, Watkins KE, Bridge H

Brain communications.. 2024 6 (5):fcae324. Epub 09/21/2024.

Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 2 registered report.

Willis HE, Caron B, Cavanaugh MR, Starling L, Ajina S, Pestilli F, Tamietto M, Huxlin KR, Watkins KE, Bridge H

Brain communications.. 2024 6 (5):fcae323. Epub 09/23/2024.

Training in cortically-blind fields confers patient-specific benefit against retinal thinning after occipital stroke.

Fahrenthold BK, Cavanaugh MR, Tamhankar M, Lam BL, Feldon SE, Johnson BA, Huxlin KR

medRxiv : the preprint server for health sciences.. 2023 December 20 Epub 12/20/2023.

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis.

Jeon KI, Kumar A, Callan CL, DeMagistris M, MacRae S, Nehrke K, Huxlin KR

Investigative ophthalmology & visual science.. 2023 October 364 (13):36. Epub 1900 01 01.

Contrast sensitivity: a fundamental limit to vision restoration after V1 damage.

Yang J, Saionz EL, Cavanaugh MR, Fahrenthold BK, Melnick MD, Tadin D, Briggs F, Carrasco M, Huxlin KR

medRxiv : the preprint server for health sciences.. 2023 September 2 Epub 09/02/2023.

Poster Session: The impact of retinal excitotoxic lesions on parallel visual streams in the ferret dorsal lateral geniculate nucleus.

Yang J, Huxlin K, Briggs F

Journal of vision.. 2023 September 123 (11):79. Epub 1900 01 01.

Poster Session: Evidence for preserved conscious orientation discrimination in perimetrically-blind fields early after V1-damage.

Cavanaugh M, Yang J, Fahrenthold B, Saionz E, Melnick M, Carrasco M, Tadin D, Huxlin K

Journal of vision.. 2023 September 123 (11):40. Epub 1900 01 01.

GABA and Glutamate in hMT+ Link to Individual Differences in Residual Visual Function After Occipital Stroke.

Willis HE, Ip IB, Watt A, Campbell J, Jbabdi S, Clarke WT, Cavanaugh MR, Huxlin KR, Watkins KE, Tamietto M, Bridge H

Stroke.. 2023 September 54 (9):2286-2295. Epub 07/21/2023.

Pathway and directional specificity of Hebbian plasticity in the cortical visual motion processing network.

Bevilacqua M, Huxlin KR, Hummel FC, Raffin E

iScience.. 2023 July 2126 (7):107064. Epub 06/07/2023.

Functional segregation within the dorsal frontoparietal network: a multimodal dynamic causal modeling study.

Raffin E, Witon A, Salamanca-Giron RF, Huxlin KR, Hummel FC

Cerebral cortex.. 2022 July 2132 (15):3187-3205. Epub 1900 01 01.

Perceptual restoration fails to recover unconscious processing for smooth eye movements after occipital stroke.

Kwon S, Fahrenthold BK, Cavanaugh MR, Huxlin KR, Mitchell JF

eLife.. 2022 June 2211 Epub 06/22/2022.

Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation.

Jeon KI, Kumar A, Wozniak KT, Nehrke K, Huxlin KR

Investigative ophthalmology & visual science.. 2022 April 163 (4):2. Epub 1900 01 01.

Blue-LIRIC in the rabbit cornea: efficacy, tissue effects, and repetition rate scaling.

Huang R, Yu D, Savage D, Wozniak K, Zheleznyak L, Knox WH, Huxlin KR

Biomedical optics express.. 2022 April 113 (4):2346-2363. Epub 03/22/2022.

Rehabilitation of visual perception in cortical blindness.

Saionz EL, Busza A, Huxlin KR

Handbook of clinical neurology.. 2022 184 :357-373. Epub 1900 01 01.

Benefits of Endogenous Spatial Attention During Visual Double-Training in Cortically-Blinded Fields.

Cavanaugh MR, Tadin D, Carrasco M, Huxlin KR

Frontiers in neuroscience.. 2022 16 :771623. Epub 04/14/2022.

Optic Tract Shrinkage Limits Visual Restoration After Occipital Stroke.

Fahrenthold BK, Cavanaugh MR, Jang S, Murphy AJ, Ajina S, Bridge H, Huxlin KR

Stroke.. 2021 November 52 (11):3642-3650. Epub 07/16/2021.

Spared perilesional V1 activity underlies training-induced recovery of luminance detection sensitivity in cortically-blind patients.

Barbot A, Das A, Melnick MD, Cavanaugh MR, Merriam EP, Heeger DJ, Huxlin KR

Nature communications.. 2021 October 2012 (1):6102. Epub 10/20/2021.

Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity.

Salamanca-Giron RF, Raffin E, Zandvliet SB, Seeber M, Michel CM, Sauseng P, Huxlin KR, Hummel FC

NeuroImage.. 2021 October 15240 :118299. Epub 06/22/2021.

Temporal evolution of the biological response to laser-induced refractive index change (LIRIC) in rabbit corneas.

Wozniak KT, Butler SC, He X, Ellis JD, Knox WH, Huxlin KR

Experimental eye research.. 2021 June 207 :108579. Epub 04/20/2021.

Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics.

Barbot A, Park WJ, Ng CJ, Zhang RY, Huxlin KR, Tadin D, Yoon G

eLife.. 2021 February 2210 Epub 02/22/2021.

Rehabilitation of cortically induced visual field loss.

Saionz EL, Feldon SE, Huxlin KR

Current opinion in neurology.. 2021 February 134 (1):67-74. Epub 1900 01 01.

Functional preservation and enhanced capacity for visual restoration in subacute occipital stroke.

Saionz EL, Tadin D, Melnick MD, Huxlin KR

Brain : a journal of neurology.. 2020 June 1143 (6):1857-1872. Epub 1900 01 01.

Localized Photoreceptor Ablation Using Femtosecond Pulses Focused With Adaptive Optics.

Dhakal KR, Walters S, McGregor JE, Schwarz C, Strazzeri JM, Aboualizadeh E, Bateman B, Huxlin KR, Hunter JJ, Williams DR, Merigan WH

Translational vision science & technology.. 2020 June 9 (7):16. Epub 06/16/2020.

Altered Sensitivity to Motion of Area MT Neurons Following Long-Term V1 Lesions.

Hagan MA, Chaplin TA, Huxlin KR, Rosa MGP, Lui LL

Cerebral cortex.. 2020 March 2130 (2):451-464. Epub 1900 01 01.

Semaphorin 3A potentiates the profibrotic effects of transforming growth factor-?1 in the cornea.

Jeon KI, Nehrke K, Huxlin KR

Biochemical and biophysical research communications.. 2020 January 8521 (2):333-339. Epub 10/24/2019.

How scars shape the neural landscape: Key molecular mediators of TGF-?1's anti-neuritogenic effects.

Jeon KI, Huxlin KR

PloS one.. 2020 15 (11):e0234950. Epub 11/24/2020.

Boosting Learning Efficacy with Noninvasive Brain Stimulation in Intact and Brain-Damaged Humans.

Herpich F, Melnick MD, Agosta S, Huxlin KR, Tadin D, Battelli L

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2019 July 1039 (28):5551-5561. Epub 05/27/2019.

Feature-based attention potentiates recovery of fine direction discrimination in cortically blind patients.

Cavanaugh MR, Barbot A, Carrasco M, Huxlin KR

Neuropsychologia.. 2019 May 128 :315-324. Epub 12/10/2017.

Impact of topical anti-fibrotics on corneal nerve regeneration in vivo.

Hindman HB, DeMagistris M, Callan C, McDaniel T, Bubel T, Huxlin KR

Experimental eye research.. 2019 April 181 :49-60. Epub 01/17/2019.

Tissue effects of intra-tissue refractive index shaping (IRIS): insights from two-photon autofluorescence and second harmonic generation microscopy.

Yu D, Brown EB, Huxlin KR, Knox WH

Biomedical optics express.. 2019 February 110 (2):855-867. Epub 01/24/2019.

The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology.

Heffer AM, Proaño J, Roztocil E, Phipps RP, Feldon SE, Huxlin KR, Sime PJ, Libby RT, Woeller CF, Kuriyan AE

PloS one.. 2019 14 (9):e0222596. Epub 09/17/2019.

Corneal myofibroblasts inhibit regenerating nerves during wound healing.

Jeon KI, Hindman HB, Bubel T, McDaniel T, DeMagistris M, Callan C, Huxlin KR

Scientific reports.. 2018 August 288 (1):12945. Epub 08/28/2018.

Author response: Visual discrimination training improves Humphrey perimetry in chronic cortically induced blindness.

Huxlin KR, Cavanaugh MR

Neurology.. 2018 February 2790 (9):437. Epub 1900 01 01.

Contrasting cellular damage after Blue-IRIS and Femto-LASIK in cat cornea.

Wozniak KT, Elkins N, Brooks DR, Savage DE, MacRae S, Ellis JD, Knox WH, Huxlin KR

Experimental eye research.. 2017 December 165 :20-28. Epub 08/31/2017.

Antifibrotic Actions of Peroxisome Proliferator-Activated Receptor ? Ligands in Corneal Fibroblasts Are Mediated by ?-Catenin-Regulated Pathways.

Jeon KI, Phipps RP, Sime PJ, Huxlin KR

The American journal of pathology.. 2017 August 187 (8):1660-1669. Epub 06/10/2017.

Visual discrimination training improves Humphrey perimetry in chronic cortically induced blindness.

Cavanaugh MR, Huxlin KR

Neurology.. 2017 May 988 (19):1856-1864. Epub 04/12/2017.

Comparable change in stromal refractive index of cat and human corneas following blue-IRIS.

Wozniak KT, Gearhart SM, Savage DE, Ellis JD, Knox WH, Huxlin KR

Journal of biomedical optics.. 2017 May 122 (5):55007. Epub 1900 01 01.

Relearning to See in Cortical Blindness.

Melnick MD, Tadin D, Huxlin KR

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.. 2016 April 22 (2):199-212. Epub 12/10/2015.

Corrigendum.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.. 2016 April 22 (2):213. Epub 01/06/2016.

Inhibitory effects of PPAR? ligands on TGF-?1-induced CTGF expression in cat corneal fibroblasts.

Jeon KI, Phipps RP, Sime PJ, Huxlin KR

Experimental eye research.. 2015 September 138 :52-8. Epub 07/02/2015.

Role of inter-hemispheric transfer in generating visual evoked potentials in V1-damaged brain hemispheres.

Kavcic V, Triplett RL, Das A, Martin T, Huxlin KR

Neuropsychologia.. 2015 February 68 :82-93. Epub 01/07/2015.

Spatial integration of optic flow information in direction of heading judgments.

Issen L, Huxlin KR, Knill D

Journal of vision.. 2015 15 (6):14. Epub 1900 01 01.

Is improved contrast sensitivity a natural consequence of visual training?

Levi A, Shaked D, Tadin D, Huxlin KR

Journal of vision.. 2015 15 (10):4. Epub 1900 01 01.

Transcranial Random Noise Stimulation Enhances Visual Learning In Healthy Adults.

Herpich F, Melnick M, Huxlin K, Tadin D, Agosta S, Battelli L

Journal of vision.. 2015 15 (12):40. Epub 1900 01 01.

Visual recovery in cortical blindness is limited by high internal noise.

Cavanaugh MR, Zhang R, Melnick MD, Das A, Roberts M, Tadin D, Carrasco M, Huxlin KR

Journal of vision.. 2015 15 (10):9. Epub 1900 01 01.

Beyond blindsight: properties of visual relearning in cortically blind fields.

Das A, Tadin D, Huxlin KR

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2014 August 2734 (35):11652-64. Epub 1900 01 01.

First demonstration of ocular refractive change using blue-IRIS in live cats.

Savage DE, Brooks DR, DeMagistris M, Xu L, MacRae S, Ellis JD, Knox WH, Huxlin KR

Investigative ophthalmology & visual science.. 2014 July 155 (7):4603-12. Epub 07/01/2014.

Inhibitory effects of PPAR? ligands on TGF-?1-induced corneal myofibroblast transformation.

Jeon KI, Kulkarni A, Woeller CF, Phipps RP, Sime PJ, Hindman HB, Huxlin KR

The American journal of pathology.. 2014 May 184 (5):1429-45. Epub 03/17/2014.

Post-DSAEK optical changes: a comprehensive prospective analysis on the role of ocular wavefront aberrations, haze, and corneal thickness.

Hindman HB, Huxlin KR, Pantanelli SM, Callan CL, Sabesan R, Ching SS, Miller BE, Martin T, Yoon G

Cornea.. 2013 December 32 (12):1567-77. Epub 1900 01 01.

Topical rosiglitazone is an effective anti-scarring agent in the cornea.

Huxlin KR, Hindman HB, Jeon KI, Bühren J, Macrae S, Demagistris M, Ciufo D, Sime PJ, Phipps RP

PloS one.. 2013 8 (8):e70785. Epub 08/05/2013.

Keratocyte apoptosis and not myofibroblast differentiation mark the graft/host interface at early time-points post-DSAEK in a cat model.

Weis AJ, Huxlin KR, Callan CL, Demagistris MA, Hindman HB

PloS one.. 2013 8 (9):e75623. Epub 09/30/2013.

Visual cortical activity reflects faster accumulation of information from cortically blind fields.

Martin T, Das A, Huxlin KR

Brain : a journal of neurology.. 2012 November 135 (Pt 11):3440-52. Epub 1900 01 01.

Different properties of visual relearning after damage to early versus higher-level visual cortical areas.

Das A, Demagistris M, Huxlin KR

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2012 April 1832 (16):5414-25. Epub 1900 01 01.

Electrophilic PPAR? ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring.

Kuriyan AE, Lehmann GM, Kulkarni AA, Woeller CF, Feldon SE, Hindman HB, Sime P, Huxlin KR, Phipps RP

Experimental eye research.. 2012 January 94 (1):136-45. Epub 12/08/2011.

Noninvasive intratissue refractive index shaping (IRIS) of the cornea with blue femtosecond laser light.

Xu L, Knox WH, Demagistris M, Wang N, Huxlin KR

Investigative ophthalmology & visual science.. 2011 October 1752 (11):8148-55. Epub 10/17/2011.

Ocular fibroblast diversity: implications for inflammation and ocular wound healing.

Xi X, McMillan DH, Lehmann GM, Sime PJ, Libby RT, Huxlin KR, Feldon SE, Phipps RP

Investigative ophthalmology & visual science.. 2011 July 152 (7):4859-65. Epub 07/01/2011.

Differential impact of partial cortical blindness on gaze strategies when sitting and walking - an immersive virtual reality study.

Iorizzo DB, Riley ME, Hayhoe M, Huxlin KR

Vision research.. 2011 May 2551 (10):1173-84. Epub 03/22/2011.

High-resolution, noninvasive, two-photon fluorescence measurement of molecular concentrations in corneal tissue.

Cui L, Huxlin KR, Xu L, Macrae S, Knox WH

Investigative ophthalmology & visual science.. 2011 April 52 (5):2556-64. Epub 04/20/2011.

The aryl hydrocarbon receptor ligand ITE inhibits TGF?1-induced human myofibroblast differentiation.

Lehmann GM, Xi X, Kulkarni AA, Olsen KC, Pollock SJ, Baglole CJ, Gupta S, Casey AE, Huxlin KR, Sime PJ, Feldon SE, Phipps RP

The American journal of pathology.. 2011 April 178 (4):1556-67. Epub 03/03/2011.

Exogenous and endogenous two-photon absorption for Intra-tissue Refractive Index Shaping (IRIS) in live corneal tissue

Xu L.; Knox W.H.; Huxlin K.R.

Optical Materials Express. 2011; 1(7): 1159-1164.

Motion-onset visual evoked potentials predict performance during a global direction discrimination task.

Martin T, Huxlin KR, Kavcic V

Neuropsychologia.. 2010 October 48 (12):3563-72. Epub 08/14/2010.

New approaches to visual rehabilitation for cortical blindness: outcomes and putative mechanisms.

Das A, Huxlin KR

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.. 2010 August 16 (4):374-87. Epub 01/25/2010.

The effect of the asphericity of myopic laser ablation profiles on the induction of wavefront aberrations.

Bühren J, Nagy L, Yoon G, MacRae S, Kohnen T, Huxlin KR

Investigative ophthalmology & visual science.. 2010 May 51 (5):2805-12. Epub 12/30/2009.

Differences in the TGF-{beta}1-induced profibrotic response of anterior and posterior corneal keratocytes in vitro.

Hindman HB, Swanton JN, Phipps R, Sime PJ, Huxlin KR

Investigative ophthalmology & visual science.. 2010 April 51 (4):1935-42. Epub 11/11/2009.

Spontaneous and training-induced visual learning in cortical blindness: characteristics and neural substrates.

Martin T, Huxlin KR

Topics in cognitive science.. 2010 April 2 (2):306-19. Epub 10/30/2009.

Contribution of optical zone decentration and pupil dilation on the change of optical quality after myopic photorefractive keratectomy in a cat model.

Bühren J, Yoon G, MacRae S, Huxlin K

Journal of refractive surgery.. 2010 March 26 (3):183-90. Epub 03/11/2010.

Potentiation of femtosecond laser intratissue refractive index shaping (IRIS) in the living cornea with sodium fluorescein.

Nagy LJ, Ding L, Xu L, Knox WH, Huxlin KR

Investigative ophthalmology & visual science.. 2010 February 51 (2):850-6. Epub 10/08/2009.

Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.

Ferguson HE, Kulkarni A, Lehmann GM, Garcia-Bates TM, Thatcher TH, Huxlin KR, Phipps RP, Sime PJ

American journal of respiratory cell and molecular biology.. 2009 December 41 (6):722-30. Epub 03/13/2009.

Perceptual relearning of complex visual motion after V1 damage in humans.

Huxlin KR, Martin T, Kelly K, Riley M, Friedman DI, Burgin WS, Hayhoe M

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2009 April 129 (13):3981-91. Epub 1900 01 01.

Optical effects of anti-TGFbeta treatment after photorefractive keratectomy in a cat model.

Bühren J, Nagy L, Swanton JN, Kenner S, MacRae S, Phipps RP, Huxlin KR

Investigative ophthalmology & visual science.. 2009 February 50 (2):634-43. Epub 10/24/2008.

Intratissue refractive index shaping (IRIS) of the cornea and lens using a low-pulse-energy femtosecond laser oscillator.

Ding L, Knox WH, Bühren J, Nagy LJ, Huxlin KR

Investigative ophthalmology & visual science.. 2008 December 49 (12):5332-9. Epub 07/18/2008.

Perceptual plasticity in damaged adult visual systems.

Huxlin KR

Vision research.. 2008 September 48 (20):2154-66. Epub 07/09/2008.

A neurochemical signature of visual recovery after extrastriate cortical damage in the adult cat.

Huxlin KR, Williams JM, Price T

The Journal of comparative neurology.. 2008 May 1508 (1):45-61. Epub 1900 01 01.

Visually-guided behavior of homonymous hemianopes in a naturalistic task.

Martin T, Riley ME, Kelly KN, Hayhoe M, Huxlin KR

Vision research.. 2007 December 47 (28):3434-46. Epub 1900 01 01.

The effect of optical zone decentration on lower- and higher-order aberrations after photorefractive keratectomy in a cat model.

Bühren J, Yoon G, Kenner S, MacRae S, Huxlin K

Investigative ophthalmology & visual science.. 2007 December 48 (12):5806-14. Epub 1900 01 01.

Photorefractive keratectomy in the cat eye: biological and optical outcomes.

Nagy LJ, MacRae S, Yoon G, Wyble M, Wang J, Cox I, Huxlin KR

Journal of cataract and refractive surgery.. 2007 June 33 (6):1051-64. Epub 1900 01 01.

Training-induced recovery of visual motion perception after extrastriate cortical damage in the adult cat.

Huxlin KR, Pasternak T

Cerebral cortex.. 2004 January 14 (1):81-90. Epub 1900 01 01.

Monochromatic ocular wavefront aberrations in the awake-behaving cat.

Huxlin KR, Yoon G, Nagy L, Porter J, Williams D

Vision research.. 2004 44 (18):2159-69. Epub 1900 01 01.

Long-term neurochemical changes after visual cortical lesions in the adult cat.

Huxlin KR, Pasternak T

The Journal of comparative neurology.. 2001 January 8429 (2):221-41. Epub 1900 01 01.

Perceptual deficits after lesions of inferotemporal cortex in macaques.

Huxlin KR, Saunders RC, Marchionini D, Pham HA, Merigan WH

Cerebral cortex.. 2000 July 10 (7):671-83. Epub 1900 01 01.

Deficits in complex visual perception following unilateral temporal lobectomy.

Huxlin KR, Merigan WH

Journal of cognitive neuroscience.. 1998 May 10 (3):395-407. Epub 1900 01 01.

Retinal ganglion cells in the albino rat: revised morphological classification.

Huxlin KR, Goodchild AK

The Journal of comparative neurology.. 1997 August 25385 (2):309-23. Epub 1900 01 01.

Excitatory convergence of Y and non-Y information channels on single neurons in the PMLS area, a motion area of the cat visual cortex.

Wang C, Dreher B, Huxlin KR, Burke W

The European journal of neuroscience.. 1997 May 9 (5):921-33. Epub 1900 01 01.

Neuronal cell death in the mammalian nervous system: the calmortin hypothesis.

Bennett MR, Huxlin KR

General pharmacology. 1996 April 27 (3):407-19. Epub 1900 01 01.

NADPH diaphorase expression in the rat retina after axotomy--a supportive role for nitric oxide.

Huxlin KR, Bennett MR

The European journal of neuroscience.. 1995 November 17 (11):2226-39. Epub 1900 01 01.

Glial reactivity in the retina of adult rats.

Huxlin KR, Dreher Z, Schulz M, Dreher B

Glia.. 1995 October 15 (2):105-18. Epub 1900 01 01.

NADPH-diaphorase expression in neurons and glia of the normal adult rat retina.

Huxlin KR

Brain research.. 1995 September 18692 (1-2):195-206. Epub 1900 01 01.

Trophic effect of collicular proteoglycan on neonatal rat retinal ganglion cells in situ.

Huxlin KR, Carr R, Schulz M, Sefton AJ, Bennett MR

Brain research. Developmental brain research.. 1995 January 1484 (1):77-88. Epub 1900 01 01.

Effect of collicular proteoglycan on the survival of adult rat retinal ganglion cells following axotomy.

Huxlin KR, Dreher B, Schulz M, Sefton AJ, Bennett MR

The European journal of neuroscience.. 1995 January 17 (1):96-107. Epub 1900 01 01.

Effect of proteoglycan purified from rat superior colliculus on the survival of murine retinal ganglion cells.

Huxlin KR, Sefton AJ, Schulz M, Bennett MR

Brain research. Developmental brain research.. 1993 August 2074 (2):207-17. Epub 1900 01 01.

The origin and development of retinal astrocytes in the mouse.

Huxlin KR, Sefton AJ, Furby JH

Journal of neurocytology.. 1992 July 21 (7):530-44. Epub 1900 01 01.

Explantation of fetal murine retinae to the chorioallantoic membrane of the chicken embryo.

Huxlin KR, Sefton AJ, Furby J

Journal of neuroscience methods.. 1992 January 41 (1):53-64. Epub 1900 01 01.

Grafting of fetal pancreata into neonatal rat brain.

Huxlin KR, Tuch BE, Sefton AJ, Dixon G

Transplantation.. 1990 May 49 (5):857-61. Epub 1900 01 01.

Iso-, allo-, and xenografting of fetal pancreata into neonatal rat brain.

Huxlin KR, Tuch BE, Sefton AJ, Dixon G

Transplantation proceedings.. 1989 October 21 (5):3807-8. Epub 1900 01 01.

Books

Handbook of Clinical Neurology (2022)

Chapter: Rehabilitation of Visual Perception in Cortical Blindness

Authors: Saionz, E.L., Busza, A. and Huxlin, K.R.

Publisher: Elsevier 2022

Textbook of Refractive Laser-Assisted Cataract Surgery (ReLACS) (2013)

Chapter: The future of ReLACS and Femtosecond Laser Ocular Surgery

Authors: Krueger, R.R, Parel, J-M., Huxlin, K.R., Knox, W.H. and Hohla, K.

Publisher: Springer, New York 2013

The Focal Encyclopedia of Photography (2007)

Chapter: Human Vision

Authors: Huxlin, K.R.

Publisher: Elsevier Inc 2007

Reprogramming The Cerebral Cortex (2006)

Chapter: Neurochemical changes underlying motion perception plasticity after visual cortex lesions

Authors: Huxlin, K.R.

Publisher: Oxford University Press 2006