Research Assistant Professor
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Department of Pharmacology and Physiology (SMD)
Credentials
Post-doctoral Training & Residency
Post-Doctoral Fellow; Center for Aging and Developmental Biology; URMC; Rochester, NY 2003 - 2006
Education
PhD | New York Medical College.Biology.2003
MS | Fordham University.Biology.1996
BS | York College, City University of New York.Biology.1994
Research
Our laboratory is interested in developing alternative treatment strategies for chronic pain, with the focus on peripheral nervous system. Persistent pain causes the sensory nerves to transmit hyperalgesic signals, which contribute to the establishment of pathological condition in central nervous sy...
Our laboratory is interested in developing alternative treatment strategies for chronic pain, with the focus on peripheral nervous system. Persistent pain causes the sensory nerves to transmit hyperalgesic signals, which contribute to the establishment of pathological condition in central nervous system, manifested as chronic pain. Conversely, manipulation of peripheral signals can reverse the chronic pain condition in central nervous system and thus restore the normal sensory perception. In particular, we study both acute and long-term pain relief by pharmacologically or mechanically manipulating sensory inputs in both orofacial neuropathic and joint inflammatory chronic pain models.
McConnell ED, Wei HS, Reitz KM, Kang H, Takano T, Vates GE, Nedergaard M
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2016 September 36 (9):1537-52. Epub 10/14/2015.
Thrane AS, Takano T, Thrane VR, Wang F, Peng W, Ottersen OP, Nedergaard M, Nagelhus EA
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2013 July 33 (7):996-9. Epub 04/24/2013.
Fujita T, Williams EK, Jensen TK, Smith NA, Takano T, Tieu K, Nedergaard M
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.. 2012 January 32 (1):e1-7. Epub 10/12/2011.
Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Thrane VR, Enger R, Haj-Yasein NN, Skare O, Holen T, Klungland A, Ottersen OP, Nedergaard M, Nagelhus EA
Proceedings of the National Academy of Sciences of the United States of America.. 2011 January 11108 (2):846-51. Epub 12/27/2010.