Chin-Yi Chu, M.S.

About Me

Faculty Appointments

Associate - Department of Pediatrics, Center for Pediatric Biomedical Research (SMD)

Credentials

Education

MS | Taiwan-National Yang-Ming University, Taipei. Biochemistry. 1997

BS | Taiwan- National Chung-Hsing University. Botany. 1995

Awards

Abstract Scholarship.

Research

Infection with respiratory syncytial virus (RSV) can cause severe respiratory diseases in infants. My research goal is identify the genetic mechanisms of susceptibility to RSV infection. My current research focuses on discovering the genomic alterations within the immune system of the infants with R...

Infection with respiratory syncytial virus (RSV) can cause severe respiratory diseases in infants. My research goal is identify the genetic mechanisms of susceptibility to RSV infection. My current research focuses on discovering the genomic alterations within the immune system of the infants with RSV infection by analyzing the patients' data obtained from high throughput sequencing, particularly RNA-Seq. I am also interested in algorithm discovery and development for next generating sequencing data analysis.

Publications

Journal Articles

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young Infants.

Mariani TJ, Qiu X, Chu CY, Wang L, Thakar J, Holden-Wiltse J, Corbett A, Topham DJ, Falsey AR, Caserta MT, Walsh EE

The Journal of infectious diseases.. 2017 November 15216 (8):1027-1037. Epub 1900 01 01.

The Healthy Infant Nasal Transcriptome: A Benchmark Study.

Chu CY, Qiu X, Wang L, Bhattacharya S, Lofthus G, Corbett A, Holden-Wiltse J, Grier A, Tesini B, Gill SR, Falsey AR, Caserta MT, Walsh EE, Mariani TJ

Scientific reports.. 2016 September 236 :33994. Epub 09/23/2016.

MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors.

Chuang KH, Whitney-Miller CL, Chu CY, Zhou Z, Dokus MK, Schmit S, Barry CT

Hepatology : official journal of the American Association for the Study of Liver Diseases.. 2015 August 62 (2):466-80. Epub 05/06/2015.

The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator.

Bhattacharya S, Zhou Z, Yee M, Chu CY, Lopez AM, Lunger VA, Solleti SK, Resseguie E, Buczynski BW, Mariani TJ, O'Reilly MA

American journal of physiology. Lung cellular and molecular physiology.. 2014 October 1307 (7):L516-23. Epub 08/22/2014.

Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor.

Chuang KH, Altuwaijri S, Li G, Lai JJ, Chu CY, Lai KP, Lin HY, Hsu JW, Keng P, Wu MC, Chang C

The Journal of experimental medicine.. 2009 May 11206 (5):1181-99. Epub 05/04/2009.

Big results from small samples: evaluation of amplification protocols for gene expression profiling.

Viale A, Li J, Tiesman J, Hester S, Massimi A, Griffin C, Grills G, Khitrov G, Lilley K, Knudtson K, Ward B, Kornacker K, Chu CY, Auer H, Brooks AI

Journal of biomolecular techniques : JBT.. 2007 July 18 (3):150-61. Epub 1900 01 01.

9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor.

Chuang KH, Lee YF, Lin WJ, Chu CY, Altuwaijri S, Wan YJ, Chang C

Molecular endocrinology.. 2005 May 19 (5):1200-12. Epub 01/13/2005.

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G (acknowledged for computational data analysis support).

Cell. 2005; 121(4): 645-57.

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