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Nikesha J. Gilmore, Ph.D.

Nikesha J. Gilmore, Ph.D.

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About Me

Faculty Appointments

Assistant Professor - Department of Surgery, Cancer Control (SMD)

Credentials

Education

PhD | University of Rochester School of Medicine & Dentistry. Pathology. 2014

MS | University of Rochester School of Medicine & Dentistry. Pathology. 2009

BS | Lincoln University. Biology. 2004

Research

Dr. Nikesha Gilmore is a tenure track Assistant Professor in the department of Surgery, Division of Supportive Care in Cancer at the University of Rochester Medical Center (URMC). She is a translational scientist with a strong background and training in molecular mechanisms, behavioral medicine, and...
Dr. Nikesha Gilmore is a tenure track Assistant Professor in the department of Surgery, Division of Supportive Care in Cancer at the University of Rochester Medical Center (URMC). She is a translational scientist with a strong background and training in molecular mechanisms, behavioral medicine, and health disparities/health equity. Dr. Gilmore’s research focuses on two main areas: 1) the development of interventions to mechanistically target frailty in older adults with cancer and to develop evidence-based solutions to foster health equity for older Black cancer survivors and 2) to improve the relationships between older Black patients with cancer and their caregivers with oncologists.

Dr. Gilmore has been awarded a NCI-funded K01, NIH-funded KL2, an NCI-funded supplement, and institution-funded pilot grants to 1) understand the underlying mechanisms of frailty in older adults with cancer, 2) investigate the safety and feasibility of an intervention aimed to treat frailty in older cancer survivors with an emphasis on older Black survivors, and 3) understand the relationship between medical mistrust and patient-centered communication in order to improve the relationships between older Black patients and their caregivers with oncologists within the Rochester community by alleviating medical mistrust through optimized patient-centered communication.

Dr. Gilmore is also passionate about finding ways to reduce barriers individuals from all marginalized backgrounds face to clinical research careers. Thus, she co-founded the “Empowering students through Research Enrichment Actives in Cancer Control and Cancer Care Delivery: EmREACh” Student Enrichment Program. EmREACh enrolls undergraduate students from disadvantaged and marginalized backgrounds with the aimed at reducing barriers that these students face in pursuing careers in healthcare.

Publications

Journal Articles

Associations of quality of social support and accurate beliefs about curability among older adults with advanced cancer.

Kehoe LA, Sohn MB, Wang L, Mohile S, Kamen C, Van Orden K, Wells M, Gilmore N, Arana-Chicas E, Gudina A, Yilmez S, Griggs L, Loh KP

Journal of geriatric oncology.. 2024 September 1015 (8):102061. Epub 09/10/2024.

"I have a doctor that handles all the other stuff." Perceptions of older adults with cancer about discussing aging-related conditions with their oncologists.

Kadambi S, Kehoe L, Wells M, Patil A, Lei L, Lewis-Thames MW, Job A, Zhang Y, Flannery M, Gilmore N, Vogel VG, Philip T, Hopkins JO, Whitehead M, Magnuson A, Mohile S, Norton SA

Journal of geriatric oncology.. 2024 September 10 :102065. Epub 09/10/2024.

Geriatric assessment for the practicing clinician: The why, what, and how.

Magnuson A, Loh KP, Stauffer F, Dale W, Gilmore N, Kadambi S, Klepin HD, Kyi K, Lowenstein LM, Phillips T, Ramsdale E, Schiaffino MK, Simmons JF, Williams GR, Zittel J, Mohile S

CA: a cancer journal for clinicians.. 2024 August 29 Epub 08/29/2024.

Systemic inflammation and changes in physical well-being in patients with breast cancer: a longitudinal study in community oncology settings.

Gilmore N, Li Y, Seplaki CL, Sohn M, Yang Y, Li CS, Loh KP, Lin PJ, Kleckner A, Mohamed M, Vertino P, Peppone L, Mustian K, Kadambi S, Corso SW, Esparaz B, Giguere JK, Mohile S, Janelsins MC

The oncologist.. 2024 August 23 Epub 08/23/2024.

An Annual Symposium on Disparities in Milwaukee, WI, with a 2023 Focus on Older Adults with Cancer.

Kamaraju S, McKoy J, Williams GR, Gilmore N, Minami C, Bylow K, Rajalingam H, Cortina CS, Beckert A, Stolley M, Bullock D, Kurzrock R, Jatoi A

Current oncology reports.. 2024 August 26 (8):855-864. Epub 05/27/2024.

A scoping review of racial, ethnic, socioeconomic, and geographic disparities in the outcomes of older adults with cancer.

Gilmore N, Grant SJ, Bethea TN, Schiaffino MK, Klepin HD, Dale W, Hardi A, Mandelblatt J, Mohile S,

Journal of the American Geriatrics Society.. 2024 June 72 (6):1867-1900. Epub 04/09/2024.

A scoping review evaluating physical and cognitive functional outcomes in cancer survivors treated with chemotherapy: charting progress since the 2018 NCI think tank on cancer and aging phenotypes.

Mohamed M, Ahmed M, Williams AM, Gilmore N, Lin PJ, Yilmaz S, Jensen-Battaglia M, Mustian K, Janelsins M, Mohile S

Journal of cancer survivorship : research and practice.. 2024 May 14 Epub 05/14/2024.

Exercise and inflammatory cytokine regulation among older adults with myeloid malignancies.

Loh KP, Wang Y, Sanapala C, Gilmore N, Netherby-Winslow C, Mendler JH, Liesveld J, Huselton E, Williams AM, Klepin HD, Jensen-Battaglia M, Mustian K, Vertino P, Susiarjo M, Janelsins MC

Experimental gerontology.. 2024 March 187 :112364. Epub 01/25/2024.

Epigenetic and inflammatory markers in older adults with cancer: A Young International Society of Geriatric Oncology narrative review.

Gilmore N, Loh KP, Liposits G, Arora SP, Vertino P, Janelsins M

Journal of geriatric oncology.. 2024 January 15 (1):101655. Epub 11/06/2023.

Stigmatizing language in caring for older adults with cancer: Common patterns of use and mechanisms to change the culture.

Kyi K, Gilmore N, Kadambi S, Loh KP, Magnuson A

Journal of geriatric oncology.. 2023 November 14 (8):101593. Epub 07/29/2023.

Associations of interleukin-6 with functional trajectories in older adults with cancer: Findings from the Health, Aging, and Body Composition Study.

Loh KP, Consagra W, Magnuson A, Baran A, Gilmore N, Giri S, LoCastro M, Isom S, Sohn MB, Williams GR, Houston DK, Nicklas B, Kritchevsky S, Klepin HD

Experimental gerontology.. 2023 June 15177 :112185. Epub 04/29/2023.

Exercise and epigenetic ages in older adults with myeloid malignancies.

Loh KP, Sanapala C, Jensen-Battaglia M, Rana A, Sohn MB, Watson E, Gilmore N, Klepin HD, Mendler JH, Liesveld J, Huselton E, LoCastro M, Susiarjo M, Netherby-Winslow C, Williams AM, Mustian K, Vertino P, Janelsins MC

European journal of medical research.. 2023 May 3028 (1):180. Epub 05/30/2023.

Effect of Yoga and Mediational Influence of Fatigue on Walking, Physical Activity, and Quality of Life Among Cancer Survivors.

Lin PJ, Altman BJ, Gilmore NJ, Loh KP, Dunne RF, Bautista J, Fung C, Janelsins MC, Peppone LJ, Melnik MK, Gococo KO, Messino MJ, Mustian KM

Journal of the National Comprehensive Cancer Network : JNCCN.. 2023 February 21 (2):153-162.e2. Epub 1900 01 01.

In Reply to the Comment on "The Relationship Between Frailty and Emotional Health in Older Patients With Advanced Cancer".

Gilmore N, Culakova E, Mohile S

The oncologist.. 2022 October 127 (10):e820-e821. Epub 1900 01 01.

Older adults with advanced cancer are selective in sharing and seeking information with social networks.

Kehoe L, Sanapala C, DiGiovanni G, Yousefi-Nooraie R, Yilmaz S, Bauer J, Loh KP, Norton S, Duberstein P, Kamen C, Gilmore N, Gudina A, Kleckner A, Mohile S, Epstein RM

Patient education and counseling.. 2022 October 105 (10):3116-3122. Epub 06/09/2022.

Racial disparities in frailty and geriatric assessment impairments in older adults with cancer in the Deep South: Results from the CARE Registry.

Williams GR, Al-Obaidi M, Harmon C, Dai C, Outlaw D, Gbolahan O, Khushman M, Nyrop KA, Gilmore N, Bhatia S, Giri S

Cancer.. 2022 June 15128 (12):2313-2319. Epub 04/11/2022.

Inflammation, Attention, and Processing Speed in Patients With Breast Cancer Before and After Chemotherapy.

Belcher EK, Culakova E, Gilmore NJ, Hardy SJ, Kleckner AS, Kleckner IR, Lei L, Heckler C, Sohn MB, Thompson BD, Lotta LT, Werner ZA, Geer J, Hopkins JO, Corso SW, Rich DQ, van Wijngaarden E, Janelsins MC

Journal of the National Cancer Institute.. 2022 May 9114 (5):712-721. Epub 1900 01 01.

Social Justice and Equity: Why Older Adults With Cancer Belong-A Life Course Perspective.

Yilmaz S, Sanapala C, Schiaffino MK, Schumacher JR, Wallington SF, McKoy JM, Canin B, Tang W, Tucker-Seeley RD, Simmons J, Gilmore N

American Society of Clinical Oncology educational book. 2022 April 42 :1-13. Epub 1900 01 01.

Evaluating the association of frailty with communication about aging-related concerns between older patients with advanced cancer and their oncologists.

Gilmore N, Xu H, Kehoe L, Kleckner AS, Moorthi K, Lei L, Mohamed MRS, Loh KPM, Culakova E, Flannery M, Ramsdale E, Duberstein PR, Canin B, Kamen C, Giri G, Watson E, Patil A, Onitilo AA, Burnette B, Janelsins M, Mohile SG

Cancer.. 2022 March 1128 (5):1101-1109. Epub 11/11/2021.

Life expectancy in older adults with advanced cancer: Evaluation of a geriatric assessment-based prognostic model.

Lund JL, Duberstein PR, Loh KP, Gilmore N, Plumb S, Lei L, Keil AP, Islam JY, Hanson LC, Giguere JK, Vogel VG, Burnette BL, Mohile SG

Journal of geriatric oncology.. 2022 March 13 (2):176-181. Epub 09/02/2021.

Relationships between cytokines and cognitive function from pre- to post-chemotherapy in patients with breast cancer.

Janelsins MC, Lei L, Netherby-Winslow C, Kleckner AS, Kerns S, Gilmore N, Belcher E, Thompson BD, Werner ZA, Hopkins JO, Long J, Cole S, Culakova E

Journal of neuroimmunology.. 2022 January 15362 :577769. Epub 11/19/2021.

Using Geriatric Assessment to Guide Conversations Regarding Comorbidities Among Older Patients With Advanced Cancer.

Kleckner AS, Wells M, Kehoe LA, Gilmore NJ, Xu H, Magnuson A, Dunne RF, Jensen-Battaglia M, Mohamed MR, O'Rourke MA, Vogelzang NJ, Dib EG, Peppone LJ, Mohile SG

JCO oncology practice.. 2022 January 18 (1):e9-e19. Epub 07/06/2021.

The Relationship Between Frailty and Emotional Health in Older Patients with Advanced Cancer.

Gilmore N, Kehoe L, Bauer J, Xu H, Hall B, Wells M, Lei L, Culakova E, Flannery M, Grossman VA, Sardari RA, Subramanya H, Kadambi S, Belcher E, Kettinger J, O'Rourke MA, Dib EG, Vogelzang NJ, Dale W, Mohile S

The oncologist.. 2021 December 26 (12):e2181-e2191. Epub 09/19/2021.

Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study.

Mohile SG, Mohamed MR, Xu H, Culakova E, Loh KP, Magnuson A, Flannery MA, Obrecht S, Gilmore N, Ramsdale E, Dunne RF, Wildes T, Plumb S, Patil A, Wells M, Lowenstein L, Janelsins M, Mustian K, Hopkins JO, Berenberg J, Anthony N, Dale W

Lancet.. 2021 November 20398 (10314):1894-1904. Epub 11/03/2021.

Health related quality of life in adult cancer survivors: Importance of social and emotional support.

Gudina AT, Cheruvu VK, Gilmore NJ, Kleckner AS, Arana-Chicas E, Kehoe LA, Belcher EK, Cupertino AP

Cancer epidemiology.. 2021 October 74 :101996. Epub 07/29/2021.

Caregiving burden of informal caregivers of older adults with advanced cancer: The effects of rurality and education.

Xu H, Kadambi S, Mohile SG, Yang S, Kehoe LA, Wells M, Culakova E, Kamen C, Obrecht S, Mohamed M, Gilmore NJ, Magnuson A, Grossman VA, Hopkins JO, Geer J, Berenberg J, Mustian K, Cupertino A, Mohile N, Loh KP

Journal of geriatric oncology.. 2021 September 12 (7):1015-1021. Epub 04/12/2021.

Measuring Biologic Resilience in Older Cancer Survivors.

Sedrak MS, Gilmore NJ, Carroll JE, Muss HB, Cohen HJ, Dale W

Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2021 July 139 (19):2079-2089. Epub 05/27/2021.

The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy.

Gilmore N, Mohile S, Lei L, Culakova E, Mohamed M, Magnuson A, Loh KP, Maggiore R, Belcher E, Conlin A, Weiselberg L, Ontko M, Janelsins M

Breast cancer research : BCR.. 2021 February 523 (1):19. Epub 02/05/2021.

Association of Polypharmacy and Potentially Inappropriate Medications With Physical Functional Impairments in Older Adults With Cancer.

Mohamed MR, Ramsdale E, Loh KP, Xu H, Patil A, Gilmore N, Obrecht S, Wells M, Nightingale G, Juba KM, Faller B, Onitilo A, Bradley T, Culakova E, Holmes H, Mohile SG

Journal of the National Comprehensive Cancer Network : JNCCN.. 2021 January 2219 (3):267-274. Epub 01/22/2021.

Excess Body Weight and Cancer-Related Fatigue, Systemic Inflammation, and Serum Lipids in Breast Cancer Survivors.

Inglis JE, Kleckner AS, Lin PJ, Gilmore NJ, Culakova E, VanderWoude AC, Mustian KM, Fernandez ID, Dunne RF, Deutsch J, Peppone LJ

Nutrition and cancer.. 2021 73 (9):1676-1686. Epub 08/19/2020.

Older adults with cancer and their caregivers - current landscape and future directions for clinical care.

Kadambi S, Loh KP, Dunne R, Magnuson A, Maggiore R, Zittel J, Flannery M, Inglis J, Gilmore N, Mohamed M, Ramsdale E, Mohile S

Nature reviews. Clinical oncology.. 2020 December 17 (12):742-755. Epub 09/02/2020.

Relationships of self-perceived age with geriatric assessment domains in older adults with cancer.

Loh KP, Duberstein P, Zittel J, Lei L, Culakova E, Xu H, Plumb S, Flannery MA, Magnuson A, Bautista J, Wittink M, Gilmore N, Targia V, Conlin A, Berenberg J, Vogel VG, Mohile SG

Journal of geriatric oncology.. 2020 July 11 (6):1006-1010. Epub 12/30/2019.

Associations of inflammation with frailty in patients with breast cancer aged 50 and over receiving chemotherapy.

Gilmore N, Kadambi S, Lei L, Loh KP, Mohamed M, Magnuson A, Cole S, Esparaz BT, Giguere JK, Mohile S, Janelsins M

Journal of geriatric oncology.. 2020 April 11 (3):423-430. Epub 04/13/2019.

Communication With Older Patients With Cancer Using Geriatric Assessment: A Cluster-Randomized Clinical Trial From the National Cancer Institute Community Oncology Research Program.

Mohile SG, Epstein RM, Hurria A, Heckler CE, Canin B, Culakova E, Duberstein P, Gilmore N, Xu H, Plumb S, Wells M, Lowenstein LM, Flannery MA, Janelsins M, Magnuson A, Loh KP, Kleckner AS, Mustian KM, Hopkins JO, Liu JJ, Geer J, Gorawara-Bhat R, Morrow GR, Dale W

JAMA oncology.. 2020 February 16 (2):196-204. Epub 1900 01 01.

Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation.

Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Gilmore N, Gan L, Que J

Developmental cell.. 2019 December 1651 (6):675-683.e4. Epub 12/05/2019.

Engaging older patients with cancer and their caregivers as partners in cancer research.

Gilmore NJ, Canin B, Whitehead M, Sedenquist M, Griggs L, Finch L, Grossman V, Targia V, Wells M, Kamen C, Flannery M, Magnuson A, Plumb S, Obrecht S, Lowenstein LM, Lopez G, Anderson J, Berenberg J, Vogel V, Bearden J, Dale W, Mohile SG

Cancer.. 2019 December 1125 (23):4124-4133. Epub 08/16/2019.

Willingness to bear adversity and beliefs about the curability of advanced cancer in older adults.

Loh KP, Mohile SG, Epstein RM, McHugh C, Flannery M, Culakova E, Lei L, Wells M, Gilmore N, Babu D, Whitehead MI, Dale W, Hurria A, Wittink M, Magnuson A, Conlin A, Thomas M, Berenberg J, Duberstein PR

Cancer.. 2019 July 15125 (14):2506-2513. Epub 03/28/2019.

Beliefs About Advanced Cancer Curability in Older Patients, Their Caregivers, and Oncologists.

Loh KP, Mohile SG, Lund JL, Epstein R, Lei L, Culakova E, McHugh C, Wells M, Gilmore N, Mohamed MR, Kamen C, Aarne V, Conlin A, Bearden J, Onitilo A, Wittink M, Dale W, Hurria A, Duberstein P

The oncologist.. 2019 June 24 (6):e292-e302. Epub 04/23/2019.

Association Between Symptom Burden and Physical Function in Older Patients with Cancer.

Pandya C, Magnuson A, Flannery M, Zittel J, Duberstein P, Loh KP, Ramsdale E, Gilmore N, Dale W, Mohile SG

Journal of the American Geriatrics Society.. 2019 May 67 (5):998-1004. Epub 03/08/2019.

Quality of Life of Caregivers of Older Patients with Advanced Cancer.

Kehoe LA, Xu H, Duberstein P, Loh KP, Culakova E, Canin B, Hurria A, Dale W, Wells M, Gilmore N, Kleckner AS, Lund J, Kamen C, Flannery M, Hoerger M, Hopkins JO, Liu JJ, Geer J, Epstein R, Mohile SG

Journal of the American Geriatrics Society.. 2019 May 67 (5):969-977. Epub 03/29/2019.

Longitudinal Relationship Between Frailty and Cognition in Patients 50 Years and Older with Breast Cancer.

Magnuson A, Lei L, Gilmore N, Kleckner AS, Lin FV, Ferguson R, Hurria A, Wittink MN, Esparaz BT, Giguere JK, Misleh J, Bautista J, Mohile SG, Janelsins MC

Journal of the American Geriatrics Society.. 2019 May 67 (5):928-936. Epub 1900 01 01.

Geriatric assessment-driven polypharmacy discussions between oncologists, older patients, and their caregivers.

Ramsdale E, Lemelman T, Loh KP, Flannery M, Kehoe L, Mullaney T, Wells M, Gilmore N, Plumb S, Mohile S

Journal of geriatric oncology.. 2018 September 9 (5):534-539. Epub 03/09/2018.

Community Oncologists' Decision-Making for Treatment of Older Patients With Cancer.

Mohile SG, Magnuson A, Pandya C, Velarde C, Duberstein P, Hurria A, Loh KP, Wells M, Plumb S, Gilmore N, Flannery M, Wittink M, Epstein R, Heckler CE, Janelsins M, Mustian K, Hopkins JO, Liu J, Peri S, Dale W

Journal of the National Comprehensive Cancer Network : JNCCN.. 2018 March 16 (3):301-309. Epub 1900 01 01.

A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model.

Haynes-Gilmore N, Banach M, Edholm ES, Lord E, Robert J

Carcinogenesis.. 2014 August 35 (8):1807-13. Epub 04/28/2014.

Nonclassical MHC class I-dependent invariant T cells are evolutionarily conserved and prominent from early development in amphibians.

Edholm ES, Albertorio Saez LM, Gill AL, Gill SR, Grayfer L, Haynes N, Myers JR, Robert J

Proceedings of the National Academy of Sciences of the United States of America.. 2013 August 27110 (35):14342-7. Epub 08/12/2013.

Effective RNAi-mediated ?2-microglobulin loss of function by transgenesis in Xenopus laevis.

Nedelkovska H, Edholm ES, Haynes N, Robert J

Biology open.. 2013 March 152 (3):335-42. Epub 01/29/2013.

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.

Bellodi C, Krasnykh O, Haynes N, Theodoropoulou M, Peng G, Montanaro L, Ruggero D

Cancer research.. 2010 July 1570 (14):6026-35. Epub 06/29/2010.