Assistant Professor
-
Department of Biomedical Genetics (SMD)
Credentials
Post-doctoral Training & Residency
Postgraduate Research in Cancer Genetics, Stanford University, Stanford, CA 2009 - 2014
Postgraduate Research in Microbiology, University of Sao Paulo, Sao Paulo, Brazil 2007 - 2009
Education
PhD | Brazil-Fac Med Ribeirao Preto.Genetics.2006
MSc | Brazil-Fac Med Ribeirao Preto.Genetics.2002
BSc | Brazil - University of Sao Paulo.Biological Science.1998
Awards
Early Investigator Advancement Program (EIAP) scholar.2023
J. Martin Brown Award for Excellence in Radiation Sciences.2017
Individual Grant (support for meeting attendance), nº 07/59639-0.2008
Young Scientist prize.2007
Environmental Mutagen Society (EMS) Travel Award, 9th International EMS Conference.2005
Research
The Mello lab is aimed at understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation. To date, very little is known about the different processes and...
The Mello lab is aimed at understanding how nuclear proteins and non-coding RNAs (ncRNAs) regulate gene transcription in pancreatic preneoplastic lesions, gaining knowledge of the process of cellular transformation and tumor initiation. To date, very little is known about the different processes and cell types that precede cancer. We are committed to describing and characterizing novel genes that play a role during early steps of tumor initiation.
We utilize physiologically relevant in vivo models and a systems biology approach, integrating multiple types of genomic data to delineate important cellular events in tumor initiation. Our research provide insights on early detection of malignant lesions, and in the development of novel strategies to treat pancreatic cancer, pancreatitis and diabetes.
Moon EJ, Mello SS, Li CG, Chi JT, Thakkar K, Kirkland JG, Lagory EL, Lee IJ, Diep AN, Miao Y, Rafat M, Vilalta M, Castellini L, Krieg AJ, Graves EE, Attardi LD, Giaccia AJ
Nature communications.. 2021 July 1412 (1):4308. Epub 07/14/2021.
Huang J, Sachdeva M, Xu E, Robinson TJ, Luo L, Ma Y, Williams N, Lopez O, Cervia LD, Yuan F, Qin X, Zhang D, Owzar K, Gokgoz N, Seto A, Okada T, Singer S, Andrulis IL, Wunder J, Lazar AJ, Rubin BP, Pipho K, Mello SS, Giudice J, Kirsch DG
Molecular cancer research : MCR.. 2020 October 18 (10):1534-1544. Epub 06/19/2020.
Chernikova SB, Nguyen RB, Truong JT, Mello SS, Stafford JH, Hay MP, Olson A, Solow-Cordero DE, Wood DJ, Henry S, von Eyben R, Deng L, Gephart MH, Aroumougame A, Wiese C, Game JC, Gy?rffy B, Brown JM
The Journal of clinical investigation.. 2018 December 3128 (12):5307-5321. Epub 10/29/2018.
Zárate-Bladés CR, Bonato VL, da Silveira EL, Oliveira e Paula M, Junta CM, Sandrin-Garcia P, Fachin AL, Mello SS, Cardoso RS, Galetti FC, Coelho-Castelo AA, Ramos SG, Donadi EA, Sakamoto-Hojo ET, Passos GA, Silva CL
The journal of gene medicine.. 2009 January 11 (1):66-78. Epub 1900 01 01.
Cardoso RS, Junta CM, Macedo C, Magalhães DA, Silveira EL, Paula MO, Marques MM, Mello SS, Zárate-Bladés CR, Nguyen C, Houlgatte R, Donadi EA, Sakamoto-Hojo ET, Passos GA
Molecular immunology.. 2006 February 43 (5):464-72. Epub 04/13/2005.