Isaac is from Ottawa, Canada. He received both his undergraduate and graduate degrees from the University of Toronto where he conducted research in the lab of Dr. Tak Mak at Princess Margaret Cancer Center. Afterwards, he joined the lab of Dr. Joan Brugge at Harvard Medical School in Boston. In Sept...
Isaac is from Ottawa, Canada. He received both his undergraduate and graduate degrees from the University of Toronto where he conducted research in the lab of Dr. Tak Mak at Princess Margaret Cancer Center. Afterwards, he joined the lab of Dr. Joan Brugge at Harvard Medical School in Boston. In September 2019, Isaac moved to Rochester, NY to open his independent lab at the University of Rochester and Wilmot Cancer Institute.
Faculty Appointments
Assistant Professor
-
Department of Biomedical Genetics (SMD)
Assistant Professor
-
Department of Pharmacology and Physiology (SMD) - Joint
Research
There has been a long-standing belief that supplementation with antioxidants could prevent or treat cancer. However, results of large-scale clinical trials have proven the opposite: supplementation with antioxidants promote, rather than prevent, cancer. The Harris Lab at the University of Rochester ...
There has been a long-standing belief that supplementation with antioxidants could prevent or treat cancer. However, results of large-scale clinical trials have proven the opposite: supplementation with antioxidants promote, rather than prevent, cancer. The Harris Lab at the University of Rochester Medical Center and Wilmot Cancer Institute focuses on uncovering the various roles of antioxidants in cancer by using in vivo mouse modeling approaches and high-throughput pharmacologic screening techniques.
Lee JJ, van de Ven RAH, Zaganjor E, Ng MR, Barakat A, Demmers JJPG, Finley LWS, Gonzalez Herrera KN, Hung YP, Harris IS, Jeong SM, Danuser G, McAllister SS, Haigis MC
Proceedings of the National Academy of Sciences of the United States of America.. 2018 July 3115 (27):7057-7062. Epub 06/18/2018.
Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D
Immunity.. 2017 June 2046 (6):1089-1090. Epub 1900 01 01.
Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D
Immunity.. 2017 April 1846 (4):675-689. Epub 1900 01 01.
Inoue S, Tomasini R, Rufini A, Elia AJ, Agostini M, Amelio I, Cescon D, Dinsdale D, Zhou L, Harris IS, Lac S, Silvester J, Li WY, Sasaki M, Haight J, Brüstle A, Wakeham A, McKerlie C, Jurisicova A, Melino G, Mak TW
Proceedings of the National Academy of Sciences of the United States of America.. 2014 February 4111 (5):1843-8. Epub 01/21/2014.
Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW
Genes & development.. 2012 September 1526 (18):2038-49. Epub 08/27/2012.
Sasaki M, Knobbe CB, Munger JC, Lind EF, Brenner D, Brüstle A, Harris IS, Holmes R, Wakeham A, Haight J, You-Ten A, Li WY, Schalm S, Su SM, Virtanen C, Reifenberger G, Ohashi PS, Barber DL, Figueroa ME, Melnick A, Zúñiga-Pflücker JC, Mak TW
Nature.. 2012 August 30488 (7413):656-9. Epub 1900 01 01.
