Olachi Mezu-Ndubuisi, M.D., O.D.
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Olachi Mezu-Ndubuisi, M.D., O.D.
View Contact & SchedulingAbout Me
Certified Specialties
Neonatal-Perinatal Medicine - American Board of Pediatrics
Pediatrics - American Board of Pediatrics
Faculty Appointments
Associate Professor - Department of Pediatrics, Neonatology (SMD)
Associate Professor - Department of Ophthalmology (SMD) - Joint
Credentials
Residency & Fellowship
Fellowship, Neonatal-Perinatal Medicine, University of Illinois College of Medicine-Chicago. 2011 - 2013
Fellowship, Neonatal-Perinatal Medicine, University of Maryland Medical Center. 2006 - 2008
Residency, Pediatrics, Louisiana State University-Shreveport. 2004 - 2006
Internship, Pediatrics, Louisiana State University-Shreveport. 2003 - 2004
Education
MD | Ross University School of Medicine-Dominica (Dominica). 2003
Awards
McPherson Eye Research Institute's Retina Research Foundation Edwin and Dorothy Gamewell Professor. 2021 - 2024
Career Development Award (K08). 2021 - 2026
Pediatric Research Loan Repayment Award. 2018 - 2019
Fellow, American Academy of Optometry. 2017
Young Investigator Award. 2017
Pediatric Research Loan Repayment Award. 2015 - 2017
ROP Star of the Month. 2015
Centennial Scholars Program Award. 2014
RRF/Joseph M. and Eula C. Lawrence Award and Travel Grant. 2013
Young Investigator's Award. 2012
Minority Research Award/Certificate. 2012
Mead Johnson Fellow's Research Travel Grant. 2012
Graduated Summa cum laude. 1998
Best Graduating Student, School of Optometry. 1998
Best Clinician Award. 1998
First Prize, Dr. Nwaba Optometry Award for Excellence. 1998
Female Motivator Award. 1992
Research
Dr. Mezu-Ndubuisi’s research studies led to the novel use of in-vivo phosphorescence lifetime imaging to measure retinal vascular oxygen tension and fluorescein angiography (FA) to depict retinal vascular abnormalities in a mouse model of oxygen-induced retinopathy (OIR). The Mezu-Ndubuisi laboratory has established in vivo retinal imaging techniques in a mouse model of OIR model that have defined unique vascular, structural and functional phenotypes in ROP, which they have correlated to histopathological evidence of neuroglia dysfunction. Her lab has expanded the use of live non-invasive optical imaging techniques to study retinal development in neonatal mice, as well as investigate the role of oxidative stress on other developing tissues, like the brain, lungs, and kidneys. Dr. Mezu-Ndubuisi’s lab is currently investigating new mechanisms of ROP pathogenesis in order to discover novel therapies, that could potentially prevent severity and progression of ROP, while avoiding systemic toxicity. One of the on-going projects is studying the efficacy and mechanism of dual therapy of intravitreal VEGF-A microparticles and topical calcitriol to restore the vascular, structural, and functional OIR phenotype.
Research Lab
Mezu-Ndubuisi Lab
Publications
Journal Articles
Zafer D, Adams T, Olson E, Stenman L, Taparli O, Eickhoff J, Cengiz P, Mezu-Ndubuisi O
Brain research.. 2022 December 11796 :148093. Epub 09/15/2022.
Mezu-Ndubuisi OJ, Song YS, Macke E, Johnson H, Nwaba G, Ikeda A, Sheibani N
Pediatric research.. 2022 June 91 (7):1677-1685. Epub 07/20/2021.
Mezu-Ndubuisi OJ, Maheshwari A
Newborn : official journal of the Global Newborn Society.. 2022 1 (1):44-57. Epub 03/31/2022.
Nwaba A, Su M, Rajamanickam V, Mezu-Nnabue K, Ubani U, Ikonne EU, Mezu-Ndubuisi O
Annals of global health.. 2022 88 (1):105. Epub 11/21/2022.
Mezu-Ndubuisi OJ, Maheshwari A
Pediatric research.. 2021 September 90 (3):513-523. Epub 10/18/2020.
Mezu-Ndubuisi OJ, Maheshwari A
Pediatric research.. 2021 May 89 (7):1619-1626. Epub 10/07/2020.
Mezu-Ndubuisi OJ
Journal of the American Heart Association.. 2021 April 610 (7):e018845. Epub 03/29/2021.
Mezu-Ndubuisi OJ, Macke EL, Kalavacherla R, Nwaba AA, Suscha A, Zaitoun IS, Ikeda A, Sheibani N
Molecular vision.. 2020 26 :257-276. Epub 04/01/2020.
Mezu-Ndubuisi OJ, Adams T, Taylor LK, Nwaba A, Eickhoff J
Eye.. 2019 March 33 (3):363-373. Epub 09/12/2018.
Mezu-Ndubuisi OJ, Wang Y, Schoephoerster J, Falero-Perez J, Zaitoun IS, Sheibani N, Gong S
Current eye research.. 2019 March 44 (3):275-286. Epub 11/09/2018.
Ley D, Hallberg B, Hansen-Pupp I, Dani C, Ramenghi LA, Marlow N, Beardsall K, Bhatti F, Dunger D, Higginson JD, Mahaveer A, Mezu-Ndubuisi OJ, Reynolds P, Giannantonio C, van Weissenbruch M, Barton N, Tocoian A, Hamdani M, Jochim E, Mangili A, Chung JK, Turner MA, Smith LEH, Hellström A,
The Journal of pediatrics.. 2019 March 206 :56-65.e8. Epub 11/22/2018.
Buck S, Rolnick K, Nwaba AA, Eickhoff J, Mezu-Nnabue K, Esenwah E, Mezu-Ndubuisi OJ
International journal of pediatrics.. 2019 2019 :9457981. Epub 06/10/2019.
Anderson A, Friedl C, Nwaba A, Rajamanickam VP, Mezu-Nnabue K, Esenwah E, Ikoro N, Suresh C, Mezu-Ndubuisi OJ.
Journal of Eye and Vision. 2018; 1(2): 6.
Mezu-Ndubuisi OJ, Taylor LK, Schoephoerster JA
Journal of ophthalmology.. 2017 2017 :9620876. Epub 05/10/2017.
Mezu-Ndubuisi OJ
Optometry and vision science : official publication of the American Academy of Optometry.. 2016 October 93 (10):1268-1279. Epub 1900 01 01.
Mezu-Ndubuisi OJ, Wanek J, Chau FY, Teng PY, Blair NP, Reddy NM, Raj JU, Reddy SP, Shahidi M
Experimental eye research.. 2014 May 122 :119-22. Epub 04/02/2014.
Mezu-Ndubuisi OJ, Teng PY, Wanek J, Blair NP, Chau FY, Reddy NM, Raj JU, Reddy SP, Shahidi M
Investigative ophthalmology & visual science.. 2013 October 2354 (10):6968-72. Epub 10/23/2013.
Mezu-Ndubuisi OJ, Agarwal G, Raghavan A, Pham JT, Ohler KH, Maheshwari A
Drugs.. 2012 May 772 (7):907-16. Epub 1900 01 01.
Mezu KR, Mezu OJ.
Journal of American Acad. of Optometry. 2001; 78(4): 32.
Pseudo-retinitis Pigmentosa – a case report.
Mezu OJ, Mezu KR, Okechi A.
Journal of Nigerian Optometric Association. 1998; : 13-15.
Books
Maxcy-Rosenau-Last Public Health & Preventive Medicine (2022)
Chapter: Visual Disorders
Authors: Hariharan L, Starr E, Garcia R, Penniecook JA, Pettey J, Hanson E, Morjaria P, Noah J, Haddad D, Mezu-Ndubuisi OJ, Winthrop KL, Ventura CV, Lansingh V.
Publisher: McGraw Hill 2022
Management and Leadership – A Guide for Clinical Professionals. (2015)
Chapter: Communicating Bad News in the Health Care Organization
Authors: Mezu-Ndubuisi, Olachi J
Publisher: Springer International Publishing 2015
Neonatal- Perinatal Medicine: Diseases of the Fetus and Infant (2014)
Chapter: Developmental Immunology
Authors: Benjamin JT, Mezu-Ndubuisi OJ, Maheshwari A
Publisher: Elsevier, MO 2014
Nutrition for the Preterm Neonate (2013)
Chapter: Minimal Enteral Feeding
Authors: Mezu-Ndubuisi O.J, Maheshwari, A.
Publisher: Springer Netherlands 2013
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