Professor
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Department of Medicine, Nephrology (SMD)
Professor
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Department of Pharmacology and Physiology (SMD) - Joint
Research
Dr. Yumei Feng Earley’s research unravels the molecular and neural mechanisms that regulate blood pressure and metabolic disorders with specific focuses below.
Neural circuitry mechanisms of blood pressure regulation and hypertension
Nearly half of the US adults have hypertension, a si...
Dr. Yumei Feng Earley’s research unravels the molecular and neural mechanisms that regulate blood pressure and metabolic disorders with specific focuses below.
Neural circuitry mechanisms of blood pressure regulation and hypertension
Nearly half of the US adults have hypertension, a significant risk factor for heart attack, stroke, and chronic kidney diseases. While studies over many years have identified specific brain areas crucial for blood pressure control, we have entered a new era in which contributions made by specific neuronal subpopulations have become identifiable and critically important. Feng Earley’s lab seeks to investigate novel roles of several populations of neurons in the hypothalamic brain regions.
It is estimated that 9.3% of the US population has diabetes, with type 2 diabetes (T2D) accounting for ~90–95% of diagnosed diabetes cases, and if present trends continue, 1 in 3 American adults may have diabetes by 2050. Diabetes is a major risk factor for kidney, retinal, peripheral nerve, and cardiovascular disease. However, the pathogenesis of T2D is poorly understood, and growing evidence points to contributions made by neural pathways. Feng Earley’s lab research stems in part from the identification of previously unrecognized neural mechanisms.
Pan S, A C Souza L, Worker CJ, Reyes Mendez ME, Gayban AJB, Cooper SG, Sanchez Solano A, Bergman RN, Stefanovski D, Morton GJ, Schwartz MW, Feng Earley Y
JCI insight.. 2024 February 139 (6)Epub 02/13/2024.