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Myra L. Coppage, Ph.D.

Myra L. Coppage, Ph.D.

Contact

Office (585) 275-6352
Fax (585) 275-2436
Administrative (585) 275-0985

About Me

Dr. Coppage is Director of the HLA/Tissue Typing laboratory, which provides state-of-the-art compatibility testing for the solid organ and tissue transplantation services including HLA typing by molecular methods, antibody screening and identification, and crossmatching.
Dr. Coppage is Director of the HLA/Tissue Typing laboratory, which provides state-of-the-art compatibility testing for the solid organ and tissue transplantation services including HLA typing by molecular methods, antibody screening and identification, and crossmatching.

Faculty Appointments

Associate Professor (Part-Time) - Department of Pathology and Laboratory Medicine (SMD)

Credentials

Education

PhD | Univ Rochester Sch Med/Dent. Pathology. 2005

MS | Univ of Houston. Study of the Future. 1987

BA | Oberlin College. Psychology. 1981

Research

Dr. Coppage's research focuses on B cells and antibodies involved in organ rejection--how they are produced, what effects they have, and what tests can be used to identify them. She is also interested in immune effects of chemotherapeutic agents and immune reconstitution following stem cell transpla...
Dr. Coppage's research focuses on B cells and antibodies involved in organ rejection--how they are produced, what effects they have, and what tests can be used to identify them. She is also interested in immune effects of chemotherapeutic agents and immune reconstitution following stem cell transplantation.

Publications

Journal Articles

Non-donor specific anti-human leukocyte antigen (HLA) antibodies are not associated with poor outcome in hematopoietic stem cell transplant recipients.

Andolina JR, Walia R, Oliva J, Baran A, Liesveld J, Becker MW, Busacco A, Coppage M

Human immunology.. 2020 August 81 (8):407-412. Epub 05/26/2020.

Bone marrow mesenchymal stromal cells from acute myelogenous leukemia patients demonstrate adipogenic differentiation propensity with implications for leukemia cell support.

Azadniv M, Myers JR, McMurray HR, Guo N, Rock P, Coppage ML, Ashton J, Becker MW, Calvi LM, Liesveld JL

Leukemia.. 2020 February 34 (2):391-403. Epub 09/06/2019.

Effects of Neddylation and mTOR Inhibition in Acute Myelogenous Leukemia.

Guo N, Azadniv M, Coppage M, Nemer M, Mendler J, Becker M, Liesveld J

Translational oncology.. 2019 April 12 (4):602-613. Epub 01/27/2019.

HLA-Mediated Platelet Refractoriness.

Schmidt AE, Refaai MA, Coppage M

American journal of clinical pathology.. 2019 March 1151 (4):353-363. Epub 1900 01 01.

Phenotypic, genotypic, and functional characterization of normal and acute myeloid leukemia-derived marrow endothelial cells.

Pizzo RJ, Azadniv M, Guo N, Acklin J, Lacagnina K, Coppage M, Liesveld JL

Experimental hematology.. 2016 May 44 (5):378-89. Epub 02/04/2016.

Leukemia specific loss of heterozygosity of MHC in a CLL patient: disease state impacts timing of confirmatory typing.

Coppage M, Iqbal A, Ahmad A, Becker MW

Human immunology.. 2013 January 74 (1):41-4. Epub 10/17/2012.

Identification of a novel HLA-B*35 variant allele, B*35:151.

Lind C, Busacco A, Huynh A, Monos D, Coppage M

Tissue antigens.. 2011 March 77 (3):258-9. Epub 1900 01 01.

Cytotoxicity of algae extracts on normal and malignant cells.

Bechelli J, Coppage M, Rosell K, Liesveld J

Leukemia research and treatment. 2011 2011 :373519. Epub 01/05/2011.

Incidence of humoral sensitization in HLA partially mismatched hematopoietic stem cell transplantation.

Leffell MS, Cao K, Coppage M, Hansen JA, Hart JM, Pereira N, Pereira S, Reinsmoen NL, Senitzer D, Smith A, Torres M, Vega R, Fuchs E

Tissue antigens.. 2009 December 74 (6):494-8. Epub 10/04/2009.

Lack of significant de novo HLA allosensitization in ventricular assist device recipients transfused with leukoreduced, ABO identical blood products.

Coppage M, Baker M, Fialkow L, Meehan D, Gettings K, Chen L, Massey HT, Blumberg N

Human immunology.. 2009 June 70 (6):413-6. Epub 03/09/2009.

Primary human splenic macrophages, but not T or B cells, are the principal target cells for dengue virus infection in vitro.

Blackley S, Kou Z, Chen H, Quinn M, Rose RC, Schlesinger JJ, Coppage M, Jin X

Journal of virology.. 2007 December 81 (24):13325-34. Epub 10/10/2007.

In vitro generation of tumor specific T cells that recognize a shared antigen of AML: molecular characterization of TCR genes.

Coppage M, Belanger T, Zauderer M, Sahasrabudhe D

Leukemia research.. 2007 February 31 (2):195-202. Epub 06/05/2006.

A renewable source of donor cells for repetitive monitoring of T- and B-cell alloreactivity.

Zand MS, Bose A, Vo T, Coppage M, Pellegrin T, Arend L, Lee FE, Bozorgzadeh A, Leong N

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.. 2005 January 5 (1):76-86. Epub 1900 01 01.

Treatment of C4d-positive acute humoral rejection with plasmapheresis and rabbit polyclonal antithymocyte globulin.

Shah A, Nadasdy T, Arend L, Brennan J, Leong N, Coppage M, Orloff M, Demme R, Zand MS

Transplantation.. 2004 May 1577 (9):1399-405. Epub 1900 01 01.

Ethanol differentially modulates the expression and activity of cell cycle regulatory proteins in rat aortic smooth muscle cells.

Sayeed S, Cullen JP, Coppage M, Sitzmann JV, Redmond EM

European journal of pharmacology.. 2002 June 12445 (3):163-70. Epub 1900 01 01.

Transient poration and cell surface receptor removal from human lymphocytes in vitro by 1 MHz ultrasound.

Brayman AA, Coppage ML, Vaidya S, Miller MW

Ultrasound in medicine & biology.. 1999 July 25 (6):999-1008. Epub 1900 01 01.

Induction of specific tolerance through mixed hematopoietic chimerism prevents chronic renal allograft rejection in a rat model.

Blom D, Morrissey NJ, Mesonero C, Coppage M, Fisher T, Zuo XJ, Jordan SC, Orloff MS

Surgery.. 1996 August 120 (2):213-9; discussion 219-20. Epub 1900 01 01.

Alterations of the interleukin-4 pathway in production of tolerance by mixed hematopoietic chimerism.

Orloff MS, DeMara EM, Coppage ML, Leong N, Zuo XJ, Prehn J, Jordan SC

Surgery.. 1995 August 118 (2):212-9. Epub 1900 01 01.

Prevention of chronic rejection and graft arteriosclerosis by tolerance induction.

Orloff MS, DeMara EM, Coppage ML, Leong N, Fallon MA, Sickel J, Zuo XJ, Prehn J, Jordan SC

Transplantation.. 1995 January 2759 (2):282-8. Epub 1900 01 01.

Induction of specific tolerance to small-bowel allografts.

Orloff MS, Fallon MA, DeMara E, Coppage ML, Leong N, Cerilli J

Surgery.. 1994 August 116 (2):222-8. Epub 1900 01 01.

Induction of tolerance to small bowel allotransplants by mixed allogeneic chimerism.

Orloff MS, Orloff SL, DeMara EM, Coppage ML, Leong N, Fallon MA

Transplantation proceedings.. 1994 June 26 (3):1585-6. Epub 1900 01 01.

Positive antiglobulin cytotoxicity crossmatch in renal allograft recipients treated with cyclosporine.

Gifford RR, Doran MM, Ruth JA, Coppage ML, Winsett OE, Fish JC

Transplantation.. 1986 October 42 (4):439-41. Epub 1900 01 01.

Books

Williams Hematology, Eighth Edition (2010)

Chapter: Human Leukocyte and Platelet Antigens

Am Soc for Histocompatibility and Immunogenetics Laboratory Man, Ed. 4 (2000)

Chapter: Isolation of Monocytes from Peripheral Blood Mononuclear Cells.