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Wing-Chi Edmund Kwok, Ph.D.

Wing-Chi Edmund Kwok, Ph.D.

Contact

Office (585) 275-6506

About Me

Professor Kwok joined the University of Rochester in 1990 after receiving his Ph.D. in Physics from Rensselaer Polytechnic Institute, and is currently an associate Professor of Imaging Sciences. His research interests in MRI include MR safety, high resolution imaging, RF coil development, water/fat ...
Professor Kwok joined the University of Rochester in 1990 after receiving his Ph.D. in Physics from Rensselaer Polytechnic Institute, and is currently an associate Professor of Imaging Sciences. His research interests in MRI include MR safety, high resolution imaging, RF coil development, water/fat imaging, dynamic contrast enhanced MRI, brain functional MRI and diffusion-weighted MRI. He has been developing RF coils and pulse sequences for research and clinical applications since 1990, and is in charge of RF coils at both Strong Memorial Hospital and UR Center for Advanced Brain Imaging & Neurophysiology. He is a recipient of six U.S. patents related to new pulse sequence and RF coil technologies.

Professor Kwok is board certified in Diagnostic Radiological Physics by the American Board of Radiology (since 1998) and certified as Medical Physicist - Diagnostic Radiological by New York State (since 2004). He supervises MRI quality assurance and ACR MRI accreditation at Strong Memorial Hospital, Golisano Children’s Hospital, East River Road, University Medical Imaging, Highland Hospital, Strong West, Penfield Crossings, Thompson Hospital and Noyes Memorial Hospital. He participates in the purchase and site planning, and conducts acceptance testing of new MRI systems. He also works with clinicians to optimize MRI protocols, provides consultation support to clinical scanning, and educates physicians and technologists on MRI technology.

Professor Kwok is also certified as an MR Safety Expert by the American Board of Magnetic Resonance Safety (since 2016). He is a member of the MRI Safety Committee at the University of Rochester Medical Center. He participates in the development of UR MRI safety policies and educational programs, and advises on the safety in scanning patients with implants or foreign objects.

Faculty Appointments

Professor - Department of Imaging Sciences (SMD)

Credentials

Education

PhD | Rensselaer Polytech Inst. Physics. 1990

MS | Rensselaer Polytech Inst. Physics. 1988

BS | Hong Kong - Non-Medical School. Physics. 1984

Awards

Cum Laude Award for an Educational Exhibit at the Annual Meeting. 2020

Roadie Award (for being the most viewed presentation in the RSNA MRI Preview). 2019

Magna Cum Laude Merit Award for an Electronic Poster Presentation in the Annual Meeting. 2012

Certificate of Merit Citation for a Scientific Exhibit in the Annual Meeting. 1999

Student Fellowship. 1985 - 1989

Full Tuition Scholarship. 1982 - 1983

Research

Patents

System and Method for Three-Dimensional Interleaved Water and Fat Image Acquisition with Chemical-Shift Correction

Issue date: April 16, 2002

Patent #: 6,373,249

Country: United States

Inventors: Wingchi E Kwok, Saara Totterman, Jianhui Zhong

Optimized Orthogonal Gradient Technique for Fast Quantitative Diffusion MRI on a Clinical Scanner

Issue date: September 11, 2001

Patent #: 6,288,540

Country: United States

Inventors: Zhong Chen, Wingchi E Kwok, Jianhui Zhong

Interleaved Water and Fat Dual-Echo Spin Echo Magnetic Resonance Imaging with Intrinsic Chemical Shift Elimination

Issue date: June 24, 2003

Patent #: 6,583,623

Country: United States

Inventors: Wingchi E Kwok, Saara Totterman, Jianhui Zhong

Intermolecular Multiple-Quantum MR Imaging in Humans

Issue date: March 04, 2003

Patent #: 6,528,997

Country: United States

Inventors: Zhong Chen, Wingchi E Kwok, Jianhui Zhong

Cryogenically Cooled Phased Array RF Receiver Coil for Magnetic Resonance Imaging

Issue date: November 30, 2004

Patent #: 6,825,664

Country: United States

Inventors: Wingchi E Kwok, Zhigang You, Jianhui Zhong

Cryogenically Cooled Phased Array RF Receiver Coil for Magnetic Resonance Imaging

Issue date: February 21, 2006

Patent #: 7,002,348

Country: United States

Inventors: Wingchi E Kwok, Zhigang You, Jianhui Zhong

Publications

Journal Articles

Radiofrequency interference in magnetic resonance imaging: Identification and rectification.

Kwok WE

Journal of clinical imaging science.. 2024 14 :33. Epub 09/05/2024.

A Study of MRI Induced Heating in Conductive Loops for Better Understanding of Burn Risk Associated with Jewelry and Piercings

Kwok, W.E.; Sheflin O.; Quattrociocchi J.; Wamser N.

Radiology Management. 2023; 45(3): 36-42.

Basic Principles of and Practical Guide to Clinical MRI Radiofrequency Coils.

Kwok WE

Radiographics : a review publication of the Radiological Society of North America, Inc.. 2022 42 (3):898-918. Epub 04/08/2022.

Spike protein multiorgan tropism suppressed by antibodies targeting SARS-CoV-2.

Brady M, McQuaid C, Solorzano A, Johnson A, Combs A, Venkatraman C, Rahman A, Leyva H, Kwok WE, Wood RW, Deane R

Communications biology.. 2021 November 224 (1):1318. Epub 11/22/2021.

Cerebrospinal fluid drainage kinetics across the cribriform plate are reduced with aging.

Brady M, Rahman A, Combs A, Venkatraman C, Kasper RT, McQuaid C, Kwok WE, Wood RW, Deane R

Fluids and barriers of the CNS.. 2020 November 3017 (1):71. Epub 11/30/2020.

In Vivo Measurement of the Human Lumbar Spine Using Magnetic Resonance Imaging to Ultrasound Registration.

Koo TK, Crews RL, Kwok WE

Journal of manipulative and physiological therapeutics.. 2019 June 42 (5):343-352. Epub 06/27/2019.

A Comparative Study of High-Resolution Chemical-Shift-Eliminated Magnetic Resonance Imaging of Finger Specimens with Microcomputed Tomography.

Kwok WE, You Z, Monu J, He H

Journal of clinical imaging science.. 2019 9 :19. Epub 05/24/2019.

A non-ionizing technique for three-dimensional measurement of the lumbar spine.

Koo TK, Kwok WE

Journal of biomechanics.. 2016 December 849 (16):4073-4079. Epub 11/02/2016.

Hierarchical CT to Ultrasound Registration of the Lumbar Spine: A Comparison with Other Registration Methods.

Koo TK, Kwok WE

Annals of biomedical engineering.. 2016 October 44 (10):2887-2900. Epub 03/28/2016.

A method of switching the signal in an MRI phantom based on trace ion currents.

Qiu Y, Kwok WE, Hornak JP

Journal of magnetic resonance.. 2014 August 245 :171-6. Epub 06/02/2014.

A Circuit for Synchronizing External Stimuli and Events to the Pulse Sequence of a Clinical Magnetic Resonance Scanner

Qiu, Y.;, Yao, W.; Kwok, W.E.; Hornak, JP.

Concepts in Magnetic Resonance Part B. 2014; 44: 50-52.

High-resolution interleaved water-fat MR imaging of finger joints with chemical-shift elimination.

Kwok WE, You Z, Seo G, Lerner A, Totterman S, Ritchlin C, Monu J

Journal of magnetic resonance imaging : JMRI.. 2011 January 33 (1):245-51. Epub 1900 01 01.

TNF is required for the induction but not the maintenance of compression-induce BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease

Papuga MO; Kwok E; You Z; Rubery PT; Dougherty PE; Pryhuber G; Beck CA; Hilton MJ; Awad HA; Schwarz EM.

J Orthop Res. 2011; 29(9): 1367-1374.

High-resolution uniform MR imaging of finger joints using a dedicated RF coil at 3T.

Kwok WE, You Z, Monu J, Seo G, Ritchlin C

Journal of magnetic resonance imaging : JMRI.. 2010 January 31 (1):240-7. Epub 1900 01 01.

Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity

Papuga MO; Proulx ST; Kwok E; You Z; Rubery PT; Dougherty PE; Hilton MJ; Awad HA; Schwarz EM.

J Orthop Res. 2010; 28(9): 1220-1228.

Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging

Proulx ST; Kwok E; You Z; Papuga MO; Beck CA; Shealy DJ; Calvi LM; Ritchlin CT; Awad HA; Boyce BF; Xing L; Schwarz EM.

Arthritis Rheum. 2008; 58(7): 2019-2029.

A potential reference point for assessment of condylar bone marrow of the temporomandibular joint on proton density weighted images

Yamamoto A; Sano T; Otonari-Yamamoto M; Nishikawa, K; Kwok E.

Cranio. 2008; 26(4): 246-252.

Predicting Regional Variations in Trabecular Bone Mechanical Properties within the Human Proximal Tibia using MR Imaging

Lancianese SL; Kwok E; Beck CA; Lerner AL.

BONE. 2008; 43(6): 1039-1046.

Theoretical studies of the effect of the dipolar field in multiple spin-echo sequences with refocusing pulses of finite duration.

Wong CK, Kennedy SD, Kwok E, Zhong J

Journal of magnetic resonance.. 2007 April 185 (2):247-58. Epub 01/10/2007.

MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis

Proulx ST; Kwok E; You Z; Beck CA; Shealy DJ; Ritchlin CT; Boyce BF; Xing L; Schwarz EM.

Annals of the New York Academy of Sciences. 2007; 1117: 106-123.

Longitudinal Assessment of Synovial, Lymph Node, and Bone Volumes in Inflammatory Arthritis in Mice using in vivo MRI and micro-CT

Proulx ST; Kwok E; You Z; Papuga MO; Beck CA; Shealy DJ; Ritchlin CT; Awad HA; Boyce BF; Xing L; Schwarz EM.

Arthritis and Rheumatism. 2007; 56(12): 4024-4037.

In vivo MRI using liquid nitrogen cooled phased array coil at 3.0 T.

Kwok WE, You Z

Magnetic resonance imaging.. 2006 July 24 (6):819-23. Epub 05/26/2006.

Temporal lobe perfusion in the deaf: MR measurement with pulsed arterial spin labeling (FAIR).

Shibata DK, Kwok E

Academic radiology.. 2006 June 13 (6):738-43. Epub 1900 01 01.

A four-element phased array coil for high resolution and parallel MR imaging of the knee.

Kwok WE, Zhong J, You Z, Seo G, Totterman SM

Magnetic resonance imaging.. 2003 November 21 (9):961-7. Epub 1900 01 01.

A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis.

Lee PL, Yiannoutsos CT, Ernst T, Chang L, Marra CM, Jarvik JG, Richards TL, Kwok EW, Kolson DL, Simpson D, Tang CY, Schifitto G, Ketonen LM, Meyerhoff DJ, Lenkinski RE, Gonzalez RG, Navia BA,

Journal of magnetic resonance imaging : JMRI.. 2003 June 17 (6):625-33. Epub 1900 01 01.

fMRI for monitoring dynamic changes in tissue oxygenation/blood flow: potential applications for tumor response to carbogen treatment.

Zhong J, Kwok WC, Okunieff P

Advances in experimental medicine and biology.. 2003 530 :449-59. Epub 1900 01 01.

Optimization of blood oxygenation level-dependent sensitivity in magnetic resonance imaging using intermolecular double-quantum coherence.

Zhong J, Chen Z, Kwok WE, Kennedy S, You Z

Journal of magnetic resonance imaging : JMRI.. 2002 December 16 (6):733-40. Epub 1900 01 01.

T1 measurements in cell cultures: a new tool for characterizing contrast agents at 1.5T.

Schmalbrock P, Hines JV, Lee SM, Ammar GM, Kwok EW

Journal of magnetic resonance imaging : JMRI.. 2001 November 14 (5):636-48. Epub 1900 01 01.

Functional MR imaging of vision in the deaf.

Shibata DK, Kwok E, Zhong J, Shrier D, Numaguchi Y

Academic radiology.. 2001 July 8 (7):598-604. Epub 1900 01 01.

fMRI of auditory stimulation with intermolecular double-quantum coherences (iDQCs) at 1.5T.

Zhong J, Kwok E, Chen Z

Magnetic resonance in medicine.. 2001 March 45 (3):356-64. Epub 1900 01 01.

Interleaved water and fat dual-echo spin echo imaging with intrinsic chemical-shift elimination.

Kwok WE, Totterman SM, Zhong J

Journal of magnetic resonance imaging : JMRI.. 2001 February 13 (2):318-23. Epub 1900 01 01.

Enhanced sensitivity to molecular diffusion with intermolecular double-quantum coherences: implications and potential applications.

Zhong J, Chen Z, Kwok E, Kennedy S

Magnetic resonance imaging.. 2001 January 19 (1):33-9. Epub 1900 01 01.

3D interleaved water and fat image acquisition with chemical-shift correction.

Kwok WE, Totterman SM, Zhong J

Magnetic resonance in medicine.. 2000 August 44 (2):322-30. Epub 1900 01 01.

In vivo intermolecular double-quantum imaging on a clinical 1.5 T MR scanner.

Zhong J, Chen Z, Kwok E

Magnetic resonance in medicine.. 2000 March 43 (3):335-41. Epub 1900 01 01.

Characteristics and pitfalls of contrast-enhanced, T1-weighted magnetization transfer images of the brain.

Higano S, Shrier DA, Numaguchi Y, Shibata DK, Kwok E

Academic radiology.. 2000 March 7 (3):156-64. Epub 1900 01 01.

Heschl and superior temporal gyri: low signal intensity of the cortex on T2-weighted MR images of the normal brain.

Yoshiura T, Higano S, Rubio A, Shrier DA, Kwok WE, Iwanaga S, Numaguchi Y

Radiology.. 2000 January 214 (1):217-21. Epub 1900 01 01.

New image contrast mechanisms in intermolecular double-quantum coherence human MR imaging

Zhong J, Chen Z, Kwok WE.

J Magn Resn Imaging. 2000; 12: 311-320.

A volume adjustable four-coil phased array for high resolution MR imaging of the hip.

Kwok WE, Lo KK, Seo G, Totterman SM

Magma.. 1999 October 9 (1-2):59-64. Epub 1900 01 01.

Functional MRI study of auditory and visual oddball tasks.

Yoshiura T, Zhong J, Shibata DK, Kwok WE, Shrier DA, Numaguchi Y

Neuroreport.. 1999 June 310 (8):1683-8. Epub 1900 01 01.

MR imaging of rabbit hip cartilage with a clinical imager and specifically designed surface coils.

Morishita Y, Rubin SJ, Hicks DG, Kwok E, Seo GS, Totterman SM

Academic radiology.. 1998 May 5 (5):365-73. Epub 1900 01 01.

MR image-guided portal verification for brain treatment field.

Yin FF, Gao Q, Xie H, Nelson DF, Yu Y, Kwok WE, Totterman S, Schell MC, Rubin P

International journal of radiation oncology, biology, physics.. 1998 February 140 (3):703-11. Epub 1900 01 01.

3D visual presentation of shoulder joint motion.

Totterman S, Tamez-Pena J, Kwok E, Strang J, Smith J, Rubens D, Parker K

Studies in health technology and informatics.. 1998 50 :27-33. Epub 1900 01 01.

Evaluation of the renal arteries in kidney donors: Value of three-dimensional phase contrast MR angiography with maximum-intensity-projection or surface rendering.

Meyers SP, Talagala SL, Totterman S, Azodo MVU, Kwok WE, Shapiro L, Shapiro R, Pabico RC, Applegate GR.

American Journal of Roentgen. 1995; 164: 117-121.

Out-of-plane motion compensation in multislice spin-echo MRI.

Riek JK, Tekalp AM, Smith WE, Kwok E

IEEE transactions on medical imaging.. 1995 14 (3):464-70. Epub 1900 01 01.

Flow compensation in MRI using a phase-corrected real reconstruction.

Riek JK, Totterman SM, Tekalp AM, Smith WE, Kwok E

Magnetic resonance in medicine.. 1993 December 30 (6):724-31. Epub 1900 01 01.

Temporomandibular joint: improved MR image quality with decreased section thickness.

Westesson PL, Kwok E, Barsotti JB, Hatala M, Paesani D

Radiology.. 1992 January 182 (1):280-2. Epub 1900 01 01.

NMR microscopy--a new biological tool.

Woods RT, Hennessy MJ, Kwok E, Hammer BE

BioTechniques.. 1989 June 7 (6):616-22. Epub 1900 01 01.