Research Associate Prof (Part-Time)
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Department of Biochemistry and Biophysics (SMD)
Credentials
Education
PhD | USSR - Non-Medical School.Genetics.1974
MS | USSR - Non-Medical School.Genetics.1971
Research
Chromosomes instability of human fungal pathogen Candida albicans. Survival due to specific chromosome rearrangements.
Candida albicans is a unicellular budding fungus that forms part of normal gut or genitalia microflora. In immunocompromized humans, however, C. albicans becomes an importan...
Chromosomes instability of human fungal pathogen Candida albicans. Survival due to specific chromosome rearrangements.
Candida albicans is a unicellular budding fungus that forms part of normal gut or genitalia microflora. In immunocompromized humans, however, C. albicans becomes an important opportunistic pathogen that can cause mortality. C. albicans is unique among other fungal pathogens by having an ability to infect divers sites of human body, including skin, nails, mucosal surfaces, as well as any other tissues or inner organs. In the laboratory, this fungus demonstrates an impressive ability to flourish under extreme pH and temperatures, as well as in other extreme environments. C. albicans possesses an acute ability to counter act the environmental stresses and to mount adequate phenotypic responses.
Specific chromosome alterations of Candida albicans: mechanisms for adaptation to pathogenicity
Rustchenko, E.;.
Evolutionary biology of bacterial and fungal pathogens. Edited by C. Nombela, G. H. Cassel, F. Baquero and J. A. Gutiérrez-Fuentes. ASM Press. 2007; : (in press).
Chromosome instability in Candida albicans.
Rustchenko, E.;.
FEMS Yeast Research. 2007; 7(3): 1-11.
Specific chromosome alterations of Candida albicans: mechanism for adaptation to pathogenicity
Rustchenko, E.;.
In: Introduction to the evolutionary biology of bacterial and fungal pathogens. Edited by C. Nombela, F. Baquero, J. A. Gutiérrez-Fuentes, ASM Press. 2007; : pp. 197-212.
