As I was growing up in the Boston area, I became infatuated with the fledgling Biotechnology Industry. I obtained my Bachelor Degree in Biotechnology with a Concentration in Biochemistry from Worcester Polytechnic Institute. I then attended the University of Vermont and earned my Ph.D. in Cell and M...
As I was growing up in the Boston area, I became infatuated with the fledgling Biotechnology Industry. I obtained my Bachelor Degree in Biotechnology with a Concentration in Biochemistry from Worcester Polytechnic Institute. I then attended the University of Vermont and earned my Ph.D. in Cell and Molecular Biology. In my thesis work, I studied the intersection of T cell receptor and Death Receptor signaling in CD4+ T cells. I was fortunate to have been supported by a slot on an Institutional T32 grant where I gained experience in the the field of Lung Biology. I then began my Postdoctoral training at the Trudeau Institute studying the immune system of mouse models of Influenza A virus infection and in a spontaneous model of autoimmunity due to deletion of a G coupled protein receptor subunit. During my first Postdoctoral training period, I moved to the University of Rochester with the lab group. I then began a second Postdoc studying the immunophenotype of peripheral blood from infants with lung disease who were born preterm. I then transitioned into a full time faculty member and have served a prominent role in the processing of primary human lung tissue as a co-Investigator on the Lung Molecular Atlas of Lung Development Program (LungMAP) and Program Manager for The Human Lung BioMolecular Multi-Scale Atlas Program (HuBMAP-Lung) project.
Faculty Appointments
Research Associate Professor
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Department of Pediatrics, Neonatology (SMD)
Credentials
Post-doctoral Training & Residency
Postdoctoral Research Associate with Dr. Gloria Pryhuber- University of Rochester Medical Center: Department of Pediatrics. 2011 - 2014
Postdoctoral Fellow with Dr. Frances Lund- University of Rochester Medical Center: Allergy, Immunology and Rheumatology. 2008 - 2011
Postdoctoral Researcher with Dr. Frances Lund-Trudeau Institute. 2006 - 2008
Education
PhD | University of Vermont.Cell and Molecular Biology.2006
BS | Worcester Polytech Inst.Biotechnology.2000
Awards
Guest Editor. Frontiers in Immunology Reserach Topic. Global Excellence in Inflammatory diseases: North America 2021..2022
Review Editor: Frontiers in Pharmacology. Respiratory Pharmacology Section..2021
Associate Editor Frontiers in Immunology.Autoimmune and Autoinflammatory Disorders Section..2021
Member of the URMC Translational Immunology and Infectious Diseases Institute (TIIDI) Faculty.2021
Associate Guest Editor: Frontiers in Immunology. Autoimmunity and Chronic Inflammation in Early Life..2020 - 2021
Peer Reviewer.2016 - 2018
Assessing RNA expression patterns in CD4+ T cells from preterm infants at the time of discharge from the Neonatal Intensive Care.2015 - 2016
Recipient of Strong Star Award.2015
Respiratory Pathogens Research Center Innovation Award..2014
Steering Committee Member of the LungMAP program..2014
Work noted by the Journal of the American Medical Association.2010
Work noted by the University of Rochester.2010
Postdoctoral Research Fellow (University of Rochester).2009 - 2010
Examining a role for G alpha q in preventing autoimmune disease (Individual award F32AI080104)..2008 - 2010
Institutional Research Training in Immunology and Infectious Diseases (Trudeau Institute T32AI049823)..2007 - 2008
Environmental Pathology and Cell Signaling Institutional Training Grant (UVM T32ES007122)..2002 - 2006
Salisbury Prize (WPI)..2000
Provost's Award (WPI)..2000
Tau Beta Pi Honors Society (WPI)..2000
Research
I am a highly collaborative Cell and Molecular Biologist who aims to develop a better understanding of diseases that affect the respiratory and immune systems in infants who are born prematurely. I work closely with physicians, nurses, clinical coordinators, basic scientific researchers, and biostat...
I am a highly collaborative Cell and Molecular Biologist who aims to develop a better understanding of diseases that affect the respiratory and immune systems in infants who are born prematurely. I work closely with physicians, nurses, clinical coordinators, basic scientific researchers, and biostatisticians within the URMC Division of Neonatology in the Department of Pediatrics as well as with many external collaborators. By studying how the immune system and lung development are altered in children born prematurely, we will begin to understand how alterations in these systems contribute to specific diseases, such as Bronchopulmonary Dysplasia, viral respiratory infections, and asthma-like morbidities. It may be possible to develop therapeutic interventions that target the inflammatory process to correct these problems. This understanding will have implications in vaccine responses, infectious diseases, and inflammatory lung diseases. Through this work, I am able to integrate my expertise in the fields of Immunology and Lung Biology while using cutting edge methodologies in a rigorous manner that will allow for reproducible results.
Börner K, Blood PD, Silverstein JC, Ruffalo M, Satija R, Teichmann SA, Pryhuber GJ, Misra RS, Purkerson JM, Fan J, Hickey JW, Molla G, Xu C, Zhang Y, Weber GM, Jain Y, Qaurooni D, Kong Y, Bueckle A, Herr BW
Gaddis N, Fortriede J, Guo M, Bardes EE, Kouril M, Tabar S, Burns K, Ardini-Poleske ME, Loos S, Schnell D, Jin K, Iyer B, Du Y, Huo BX, Bhattacharjee A, Korte J, Munshi R, Smith V, Herbst A, Kitzmiller JA, Clair GC, Carson JP, Adkins J, Morrisey EE, Pryhuber GS, Misra R, Whitsett JA, Sun X, Heathorn T, Paten B, Prasath VBS, Xu Y, Tickle T, Aronow BJ, Salomonis N,
American journal of respiratory cell and molecular biology.. 2024 February 70 (2):129-139. Epub 1900 01 01.
Does maternal stress associate with premature milk cortisol, milk IgA and infant health: a cohort study
Casey B Rosen-Carole, Susan Greenman, Hongyue Wang, Sharvari Sonawane, Ravi Misra, Tom O'Connor, Kirsi Jarvinen-Seppo, Carl D'Angio and Bridget E Young.
Frontiers in Nutrition, section Nutritional Immunology. 2024; .
Bhattacharya, S.; Myers, J.A.; Baker, C.; Guo, M.; Danopoulos, S.; Myers, J.R.; Bandyopadhyay, G.; Romas, S.T.; Huyck, H.L.; Misra, R.S, J Dutra, J Holden-Wiltse, A McDavid, JM Ashton, D Al Alam, S Potter, JA Whitsett, Y Xu, GS Pryhuber and TJ Mariani.
Jain S, Pei L, Spraggins JM, Angelo M, Carson JP, Gehlenborg N, Ginty F, Gonçalves JP, Hagood JS, Hickey JW, Kelleher NL, Laurent LC, Lin S, Lin Y, Liu H, Naba A, Nakayasu ES, Qian WJ, Radtke A, Robson P, Stockwell BR, Van de Plas R, Vlachos IS, Zhou M, , Börner K, Snyder MP
Nature cell biology.. 2023 August 25 (8):1089-1100. Epub 07/19/2023.
Guo M, Morley MP, Jiang C, Wu Y, Li G, Du Y, Zhao S, Wagner A, Cakar AC, Kouril M, Jin K, Gaddis N, Kitzmiller JA, Stewart K, Basil MC, Lin SM, Ying Y, Babu A, Wikenheiser-Brokamp KA, Mun KS, Naren AP, Clair G, Adkins JN, Pryhuber GS, Misra RS, Aronow BJ, Tickle TL, Salomonis N, Sun X, Morrisey EE, Whitsett JA, , Xu Y
Nature communications.. 2023 July 2914 (1):4566. Epub 07/29/2023.
Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED, Subramanian A, Smillie C, Jagadeesh KA, Duong ET, Fiskin E, Triglia ET, Ansari M, Cai P, Lin B, Buchanan J, Chen S, Shu J, Haber AL, Chung H, Montoro DT, Adams T, Aliee H, Allon SJ, Andrusivova Z, Angelidis I, Ashenberg O, Bassler K, Bécavin C, Benhar I, Bergenstråhle J, Bergenstråhle L, Bolt L, Braun E, Bui LT, Callori S, Chaffin M, Chichelnitskiy E, Chiou J, Conlon TM, Cuoco MS, Cuomo ASE, Deprez M, Duclos G, Fine D, Fischer DS, Ghazanfar S, Gillich A, Giotti B, Gould J, Guo M, Gutierrez AJ, Habermann AC, Harvey T, He P, Hou X, Hu L, Hu Y, Jaiswal A, Ji L, Jiang P, Kapellos TS, Kuo CS, Larsson L, Leney-Greene MA, Lim K, Litvi?uková M, Ludwig LS, Lukassen S, Luo W, Maatz H, Madissoon E, Mamanova L, Manakongtreecheep K, Leroy S, Mayr CH, Mbano IM, McAdams AM, Nabhan AN, Nyquist SK, Penland L, Poirion OB, Poli S, Qi C, Queen R, Reichart D, Rosas I, Schupp JC, Shea CV, Shi X, Sinha R, Sit RV, Slowikowski K, Slyper M, Smith NP, Sountoulidis A, Strunz M, Sullivan TB, Sun D, Talavera-López C, Tan P, Tantivit J, Travaglini KJ, Tucker NR, Vernon KA, Wadsworth MH, Waldman J, Wang X, Xu K, Yan W, Zhao W, Ziegler CGK, ,
Nature medicine.. 2021 March 27 (3):546-559. Epub 03/02/2021.
Misra RS, Shi G, Moreno-Garcia ME, Thankappan A, Tighe M, Mousseau B, Kusser K, Becker-Herman S, Hudkins KL, Dunn R, Kehry MR, Migone TS, Marshak-Rothstein A, Simon M, Randall TD, Alpers CE, Liggitt D, Rawlings DJ, Lund FE
The Journal of experimental medicine.. 2010 August 2207 (8):1775-89. Epub 07/12/2010.
