Associate Professor
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Department of Microbiology and Immunology (SMD)
Associate Professor
-
Department of Biomedical Genetics (SMD) - Joint
Credentials
Post-doctoral Training & Residency
Associate Research Scientist, Department of Pathology, Yale School of Medicine, USA 2011 - 2013
Cancer Research Institute fellow, Department of Physics, Pennsylvania State University, USA 2006 - 2010
Education
PhD | Germany-U Wurzburg.Bioinformatics.2006
MSc with certificate | India-Univ of Pune, Pune.Microbiology and Computational Biology.2003
BSc | India-Univ of Pune, Pune.Microbiology and Mathematics.2001
Awards
Novel Biostatistical and Epidemiologic Methods (NBEM) Awards.2016 - 2017
PhRMA research starter award in informatics.2015 - 2016
Beutner Speaker.2014
Cancer-Research-Institute fellowship.2008 - 2010
Shankar Subramaniam award in systems biology research.2007
The Association for the Study of Animal Behavior fellowship.2001
Research
Thakar lab uses systems biology approaches to identify immune signatures that can predict outcome of an immune response to infections or vaccinations. We develop computational tools to model probable trajectories of the immune r...
Thakar lab uses systems biology approaches to identify immune signatures that can predict outcome of an immune response to infections or vaccinations. We develop computational tools to model probable trajectories of the immune response which then allows us to identify parameters that can predict future outcomes of the disease. This has direct implications in early diagnosis. The models also reveal the mechanisms of pathogenesis. This work is based on multi-parameter datasets including gene expression, serum cytokine levels and known information about signaling and metabolic pathways.
Niarakis A, Laubenbacher R, An G, Ilan Y, Fisher J, Flobak Å, Reiche K, Rodríguez Martínez M, Geris L, Ladeira L, Veschini L, Blinov ML, Messina F, Fonseca LL, Ferreira S, Montagud A, Noël V, Marku M, Tsirvouli E, Torres MM, Harris LA, Sego TJ, Cockrell C, Shick AE, Balci H, Salazar A, Rian K, Hemedan AA, Esteban-Medina M, Staumont B, Hernandez-Vargas E, Martis B S, Madrid-Valiente A, Karampelesis P, Sordo Vieira L, Harlapur P, Kulesza A, Nikaein N, Garira W, Malik Sheriff RS, Thakar J, Tran VDT, Carbonell-Caballero J, Safaei S, Valencia A, Zinovyev A, Glazier JA
NPJ systems biology and applications.. 2024 November 3010 (1):141. Epub 11/30/2024.
Dräger A, Helikar T, Barberis M, Birtwistle M, Calzone L, Chaouiya C, Hasenauer J, Karr JR, Niarakis A, Rodríguez Martínez M, Saez-Rodriguez J, Thakar J
Bioinformatics.. 2021 November 537 (21):3702-3706. Epub 1900 01 01.
Seppo AE, Bu K, Jumabaeva M, Thakar J, Choudhury R, Yonemitsu C, Bode L, Martina CA, Allen M, Tamburini S, Piras E, Wallach DS, Looney RJ, Clemente JC, Järvinen KM
Allergy.. 2021 November 76 (11):3489-3503. Epub 05/14/2021.
Seppo AE, Choudhury R, Pizzarello C, Palli R, Fridy S, Rajani PS, Stern J, Martina C, Yonemitsu C, Bode L, Bu K, Tamburini S, Piras E, Wallach DS, Allen M, Looney RJ, Clemente JC, Thakar J, Järvinen KM
Frontiers in immunology.. 2021 12 :741513. Epub 10/11/2021.
Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, Chikina M, Fribourg M, Hayot F, Schmolke M, Meng H, Wetmur J, García-Sastre A, Kleinstein SH, Sealfon SC
Journal of virology.. 2015 October 89 (20):10190-205. Epub 07/29/2015.
Thakar J, Schmid S, Duke JL, García-Sastre A, Kleinstein SH
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.. 2013 November 33 (11):700-8. Epub 06/17/2013.
Watve M, Thakar J, Kale A, Puntambekar S, Shaikh I, Vaze K, Jog M, Paranjape S
Animal cognition.. 2002 December 5 (4):253-9. Epub 11/16/2002.
Protein diffusion in to thermally evaporated lipid films: role of protein charge/mass ratio.
Gole, A.; Thakar, J.; Sastry, M.
Colloids and surfaces B: Biointerfaces. 2002; 28(2): 209-214.
Do bee-eaters have a theory of mind?
Smitha, B.; Thakar, J.; Watve, M.
Current Science. 1999; 76(4): 574-577.
Books
Occupational Health and the Service Member
(2019)
Chapter: BIOLOGICAL MONITORING
Authors: Timothy M. Mallon*, Richard Phipps, Juilee Thakar, Collynn Woeller, Dean P. Jones, Douglas I. Walker, Karan Uppal, Mark Utell and Thomas Thatcher
Publisher:
Office of The Surgeon General Borden Institute US Army Medical Department Center 2019
Computational Cell Biology
(2018)
Chapter: Developing Network Models of Multiscale Host Responses Involved in Infections and Diseases.
Authors: Rohith Palli and Juilee Thakar
Publisher:
Springer Science and Humana Press, New York 2018
Emerging Trends in Antibacterial Discovery
(2011)
Chapter: Mathematical Models as Tools to Enable Infectious Diseases Research
Authors: Juilee Thakar and Eric Harvill
Publisher:
Caister Academic Press 2011
Handbook of Large-Scale Random Networks
(2009)
Chapter: Toward understanding the structure and function of cellular interaction networks
Authors: Juilee Thakar, Claire Christensen and Réka Albert
Publisher:
Springer Verlag and Bolyai Mathematical Society 2009
Handbook on Biological Networks
(2009)
Chapter: Boolean Networks in Inference and Dynamic Modeling of Biological Systems at the Molecular and Physiological Level
