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Mostafa R. Mohamed, M.B.B.Ch., M.Sc.

Contact

Call Center (585) 276-3000

About Me

Faculty Appointments

Assistant Professor - Department of Public Health Sciences (SMD)

Credentials

Awards

Finalist, International Society for Geriatric Oncology Young Investigator Award. 2023

Wilmot Doctoral Cancer Research Fellowship. 2022

Dean's Fellowship Scholarship. 2019

Outstanding Abstract Award. 2019

Research

Dr. Mostafa Mohamed's research focuses on the intersection of cancer and aging, aiming to improve health outcomes for older adults with cancer. As a clinician and cancer epidemiologist, Dr. Mohamed brings a robust background and training in study design, causal inference, medical oncology, and geria...
Dr. Mostafa Mohamed's research focuses on the intersection of cancer and aging, aiming to improve health outcomes for older adults with cancer. As a clinician and cancer epidemiologist, Dr. Mohamed brings a robust background and training in study design, causal inference, medical oncology, and geriatric oncology research. His research interests center on two primary areas: firstly, evaluating polypharmacy and the use of high-risk medications in older adults with cancer; and secondly, exploring treatment decision-making processes, including chemotherapy dosing decisions, treatment tolerability, and efficacy of cancer therapeutics in this population. Dr Mohamed serves as a member of Junior Faculty Board of Cancer and Aging Research Group (CARG), as well as an Editorial Board member for the Journal of Geriatric Oncology.

Publications

Journal Articles

A scoping review evaluating physical and cognitive functional outcomes in cancer survivors treated with chemotherapy: charting progress since the 2018 NCI think tank on cancer and aging phenotypes

Mohamed M, Ahmed M, Williams AM, Gilmore N, Lin PJ, Yilmaz S, Jensen-Battaglia M, Mustian K, Janelsins M, Mohile S.

Journal of Cancer Survivorship. 2024; : 1-42.

Decreasing polypharmacy in older adults with cancer: A pilot cluster-randomized trial protocol

Ramsdale E, Mohamed M, Holmes HM, ZubkoffL, Bauer J, Norton SA, Mohile S.

Journal of geriatric oncology. 2024; 15(2): 101687.

Primary treatment modification and treatment tolerability among older chemotherapy recipients with advanced cancer

Mohamed MR, Rich DQ, Seplaki C, Lund JL, Flannery M, Culakova E, Magnuson A, Wells M, Tylock R, Mobile SG.

AMA Network Open. 2024; 7(2): e2356106.

Modifiable fall risk factors among older adults with advanced cancer: Secondary analysis of a cluster-randomized clinical trial

Jensen-Battaglia M, Mohamed M, Loh KP, Wells M, Tylock R, Ramsdale E, Canin B, Geer J, O'Rourke MA, Liu JJ, Seplaki CL.

Journal of geriatric oncology. 2023; 14(8): 101650.

Older adults with advanced cancer report pain not captured by clinician-graded Common Terminology Criteria for Adverse Events (CTCAE)

Arana-Chicas E, Culakova E, Mohamed MR, Tylock R, Wells M, Flannery M, Mustian KM, Cupertino AP, Magnuson A, Mobile SG.

Journal of Geriatric Oncology. 2023; 14(3).

Association ofpolypharmacy and potential drug-drug interactions with adverse treatment outcomes in older adults with advanced cancer

Mohamed MR, Mohile SG, Juba KM, Awad H, Wells M, Loh KP, Flannery M, Culakova E, Tylock RG, Ramsdale EE.

Cancer. 2023; 129(7): 1096-104.

Effects of a Geriatric Assessment Intervention on Patient-Reported Symptomatic Toxicity in Older Adults With Advanced Cancer

Culakova E, Mobile SG, Peppone L, Ramsdale E, Mohamed M, Xu H, Wells M, Loh KP, Magnuson A.

Journal of Clinical Oncology. 2023; 41(4): 835-46.

External Validation of Risk Factors for Unplanned Hospitalization in Older Adults With Advanced Cancer Receiving Chemotherapy

Mohamed MR, Loh KP, Mobile SG, Sohn M, Webb T, Wells M, Yilmaz S, Tylock R, Culakova E, Magnuson A, Sun CL.

Journal of the National Comprehensive Cancer Network. 2023; 21(3): 273-80.

An Unsupervised Machine Leaming Approach to Evaluating the Association of Symptom Clusters With Adverse Outcomes Among Older Adults With Advanced Cancer: A Secondary Analysis of a Randomized Clinical Trial

Xu H, Mohamed M, Flannery M, Peppone L, Ramsdale E, Loh KP, Wells M, Jamieson L, Vogel VG, Hall BA, Mustian K.

JAMA network open. 2023; 6(3): e234198.

Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment.

Mohamed M, Ramsdale E, Yu V, Otto E, Juba K, Awad H, Moorthi K, Plumb S, Patil A, Vogelzang N, Dib E.

The Oncologist. 2022; 27(7): e580-8.

A Geriatric Assessment Intervention to Reduce Treatment Toxicity Among Older Adults With Advanced Lung Cancer: A Subgroup Analysis From a Cluster Randomized Controlled Trial

Presley CJ, Mohamed MR, Culakova E, Flannery M, Vibhakar PH, Hoyd R, Amini A, VanderWalde N, Wong ML, Tsubata Y, Spakowicz DJ.

Frontiers in Oncology. 2022; : 1203.

Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment

Mohamed M, Ramsdale E, Yu V, Otto E, Juba K, Awad H, Moorthi K, Plumb S, Patil A, Vogelzang N, Dib E.

The Oncologist. 2022; 27(7): e580-8.

Evaluating the association of frailty with communication about aging­related concerns between older patients with advanced cancer and their oncologists

Gilmore N, Xu H, Kehoe L, Kleckner AS, Moorthi K, Lei L, Mohamed MR, Loh KP, Culakova E, Flannery M, Ramsdale E.

Cancer. 2022; 128(5): 1101-9.

Longitudinal changes in cognitive function in a nationwide cohort study of patients with lymphoma treated with chemotherapy

Janelsins MC, Mohamed M, Peppone LJ, Magnuson A, Belcher EK, Melnik M, Dakhil S, Geer J, Kamen C, Minasian L, Reagan PM.

JNCI: Journal of the National Cancer Institute. 2022; 114(1): 47-59.

Using geriatric assessment to guide conversations regarding comorbidities among older patients with advanced cancer

Kleckner AS, Wells M, Kehoe LA, Gilmore NJ, Xu H, Magnuson A, Dunne RF, Jensen-Battaglia M, Mohamed MR, O'Rourke MA, Vogelsong NJ.

JCO Oncology Practice. 2022; 18(1): e9-19.

The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy.

Gilmore N, Mohile S, Lei L, Culakova E, Mohamed M, Magnuson A, Loh KP, Maggiore R, Belcher E, Conlin A, Weiselberg L, Ontko M, Janelsins M

Breast cancer research : BCR.. 2021 February 523 (1):19. Epub 02/05/2021.

Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study

Mohile SG, Mohamed MR, Xu H, Culakova E, Loh KP, Magnuson A, Flannery MA, Obrecht S, Gilmore N, Ramsdale E, Dunne RF.

The Lancet. 2021; 398(10314): 1894-904.

Prevalence of and factors associated with treatment modification at first cycle in older adults with advanced cancer receiving palliative treatment

Mohamed MR, Kyi K, Mohile SG, Xu H, Culakova E, Loh KP, Flannery M, Obrecht S, Ramsdale E, Patil A, Dunne RF.

Journal of geriatric oncology. 2021; 12(8): 1208-13.

Research priorities to address polypharmacy in older adults with cancer

Nightingale G, Mohamed MR, Holmes HM, Sharma M, Ramsdale E, Lu-Yao G, Chapman A.

Journal of geriatric oncology. 2021; 12(6): 964-70.

Caregiver-oncologist prognostic concordance, caregiver mastery, and caregiver psychological health and quality of life

Loh KP, Mohamed MR, Kadambi S, Culakova E, Xu H, Magnuson A, Flannery M, Duberstein PR, Epstein RM, McHugh C, Nipp RD.

The oncologist. 2021; 26(4): 310-7.

Association of Polypharmacy and Potentially Inappropriate Medications With Physical Functional Impairments in Older Adults With Cancer

Mohamed MR, Ramsdale E, Loh KP, Xu H, Patil A, Gilmore N, Obrecht S, Wells M, Nightingale G, Juba KM, Faller B.

Journal of the National Comprehensive Cancer Network. 2021; : 1-8.

Associations of Polypharmacy and Inappropriate Medications with Adverse Outcomes in Older Adults with Cancer: A Systematic Review and Meta-Analysis

Mohamed MR, Ramsdale E, Loh KP, Arastu A, Xu H, Obrecht S, Castillo D, Sharma M, Holmes HM, Nightingale G, Juba KM.

The oncologist. 2020; 25(1): e94.

Associations of inflammation with frailty in patients with breast cancer aged 50 and over receiving chemotherapy

Gilmore N, Kadambi S, Lei L, Loh KP, Mohamed M, Magnuson A, Cole S, Esparaz BT, Giguere JK, Mohile S, Janelsins M.

Journal of Geriatric Oncology. 2020; 11(3): 423-30.

Assessment ofFinancial Toxicity among Older Adults with Advanced Cancer

Arastu A, Patel A, Mohile SG, Ciminelli J, Kaushik R, Wells M, Culakova E, Lei L, Xu H, Dougherty DW, Mohamed MR, Hill E, Duberstein P, Flannery MA, Kamen CS, Pandya C, Berenberg JL, Aame Grossman VG, Liu Y, Loh KP.

JAMA Netw Open. 2020; 3(12): e2025810.

Older adults with cancer and their caregivers - current landscape and future directions for clinical care

Kadambi S, Loh KP, Dunne R, Magnuson A, Maggiore R, Zittel J, Flannery M, Inglis J, Gilmore N, Mohamed M, Ramsdale E, Mohile S.

Nat Rev Clin Oncol. 2020; 17(12): 742-755.

Impact of chemotherapy for breast cancer on leukocyte DNA methylation landscape and cognitive function: a prospective study

Yao S, Hu Q, Kerns S, Yan L, Onitilo AA, Misleh J, Young K, Lei L, Bautista J, Mohamed M, Mohile SG.

Clinical epigenetics. 2019; 11(1): 1-0.

Beliefs about advanced cancer curability in older patients, their caregivers, and oncologists

Loh KP, Mohile SG, Lund JL, Epstein R, Lei L, Culakova E, McHugh C, Wells M, Gilmore N, Mohamed MR, Kamen C.

The oncologist. 2019; 24(6): e292.

Systemic Inflammation and Changes in Physical Well-Being in Patients with Breast Cancer: A Longitudinal Study in Community Oncology Settings

Gilmore, N., Li, Y., Seplaki, C.L., Sohn, M., Wang, Y., Chin-Shang, L., Loh, KP., Lin, PJ., Kleckner, A., Mohamed, M., Vertino, P., Peppone, L., Mustian, K., Kadambi, S., Corso, S.W., Esparaz, B., Giguere, J.K., Mohile, S., Janelsins, M.

The Oncologist. .

Dynamic changes of decision regret and its associated factors during treatment in older adults with advanced cancer

Flannery M, Culakova E, Mohamed M, Tylock R, Magnuson A, Loh KP, Hongying S, Wells M, Mohile SG.

Cancer. .

Fatigue, Physical Function, and the Context of Social Vulnerability for Older Adults with Cancer

Jensen-Battaglia M, Delmerico A, Mohamed M, Loh KP, Wells M, Tylock R, Ramsdale E, Mustian K, Mohile S, Seplaki CL, Gilmore N.

JNCI Spectrum. .

Effect of polypharmacy on functional decline among older adults with advanced cancer receiving systemic treatment

Mohamed MR, Mohile S, Juba K, Awad H, Flannery M, Culakova E, Ramsdale E.

Journal of American Geriatric Society. .

Books

Cancer and the Aging Population. In Psychological Aspects of Cancer 2022 (2022)

Authors: Tsang M, Kadambi S, Mohamed M, Rai M, Parsi M, Loh KP.

Publisher: Springer, Cham 2022