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Monica Javidnia, Ph.D.

Monica Javidnia, Ph.D.

Contact

Call Center (585) 276-3000

About Me

Faculty Appointments

Adjunct Senior Instructor - Department of Neurology, Center for Health and Technology (SMD)

Credentials

Post-doctoral Training & Residency

University of Rochester Medical Center 2017 - 2020

Education

PhD | Georgetown University. Pharmacology. 2017

MS | University of Texas at Dallas. Applied Cognition and Neuroscience. 2012

BS | University of Texas at Dallas. Neuroscience. 2011

Awards

TEDMED Research Scholar. 2019 - 2020

Research

My primary research projects are
1. Relating symptomatic treatments to Parkinson’s disease patient outcomes and self-reported symptom burden
2. Using digital tools (e.g., smartphone applications, sensors) to measure drug pharmacodynamics, disease progression, and clinically-meaningful outcomes...
My primary research projects are
1. Relating symptomatic treatments to Parkinson’s disease patient outcomes and self-reported symptom burden
2. Using digital tools (e.g., smartphone applications, sensors) to measure drug pharmacodynamics, disease progression, and clinically-meaningful outcomes/events (e.g., time to treatment, falls, cognitive impairment)

Publications

Journal Articles

A Disease Progression Model to Quantify the Nonmotor Symptoms of Parkinson's Disease in Participants With Leucine-Rich Repeat Kinase 2 Mutation.

Ahamadi M, Mehrotra N, Hanan N, Yee KL, Gheyas F, Anton J, Bani M, Boroojerdi B, Smit H, Weidemann J, Macha S, Thuillier V, Chen C, Yang M, Williams-Gray CH, Stebbins GT, Pagano G, Hang Y, Marek K, Venuto CS, Javidnia M, Dexter D, Pedata A, Stafford B, Akalu M, Stephenson D, Romero K, Sinha V,

Clinical pharmacology and therapeutics.. 2021 August 110 (2):508-518. Epub 06/12/2021.

Responses to 10 common criticisms of anti-racism action in STEMM.

Gosztyla ML, Kwong L, Murray NA, Williams CE, Behnke N, Curry P, Corbett KD, DSouza KN, Gala de Pablo J, Gicobi J, Javidnia M, Lotay N, Prescott SM, Quinn JP, Rivera ZMG, Smith MA, Tang KTY, Venkat A, Yamoah MA

PLoS computational biology.. 2021 July 17 (7):e1009141. Epub 07/15/2021.

Isradipine plasma pharmacokinetics and exposure-response in early Parkinson's disease.

Venuto CS, Yang L, Javidnia M, Oakes D, James Surmeier D, Simuni T

Annals of clinical and translational neurology.. 2021 March 8 (3):603-612. Epub 01/18/2021.

Predictive Value of Verbatim Parkinson's Disease Patient-Reported Symptoms of Postural Instability and Falling.

Javidnia M, Arbatti L, Hosamath A, Eberly SW, Oakes D, Shoulson I

Journal of Parkinson's disease.. 2021 11 (4):1957-1964. Epub 1900 01 01.

Innovative Approaches for Slowing Disease Progression in Parkinson's Disease: Takeaways from the 14th Annual International Society for Central Nervous System Clinical Trials and Methodology Scientific Meeting.

Javidnia M, Frasier M, Shoulson I, Turkoz I, Budur K

Innovations in clinical neuroscience.. 2020 January 117 (1-3):14-19. Epub 1900 01 01.

Pharmacotherapy Use for Non-Motor Symptoms Among de novo Parkinson's Disease Parkinson's Progression Markers Initiative Participants.

Javidnia M, Shoulson I, Kieburtz K, Venuto C

Journal of Parkinson's disease.. 2020 10 (3):1239-1243. Epub 1900 01 01.

A Proposed Roadmap for Parkinson's Disease Proof of Concept Clinical Trials Investigating Compounds Targeting Alpha-Synuclein.

Merchant KM, Cedarbaum JM, Brundin P, Dave KD, Eberling J, Espay AJ, Hutten SJ, Javidnia M, Luthman J, Maetzler W, Menalled L, Reimer AN, Stoessl AJ, Weiner DM,

Journal of Parkinson's disease.. 2019 9 (1):31-61. Epub 1900 01 01.

Tau clearance improves astrocytic function and brain glutamate-glutamine cycle.

Hebron ML, Javidnia M, Moussa CE

Journal of the neurological sciences.. 2018 August 15391 :90-99. Epub 06/12/2018.

Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy.

Javidnia M, Hebron ML, Xin Y, Kinney NG, Moussa CE

Journal of Alzheimer's disease : JAD.. 2017 60 (2):461-481. Epub 1900 01 01.

Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors.

DiRaddo JO, Miller EJ, Bowman-Dalley C, Wroblewska B, Javidnia M, Grajkowska E, Wolfe BB, Liotta DC, Wroblewski JT

Molecular pharmacology.. 2015 September 88 (3):450-9. Epub 06/18/2015.

Klotho regulates retinal pigment epithelial functions and protects against oxidative stress.

Kokkinaki M, Abu-Asab M, Gunawardena N, Ahern G, Javidnia M, Young J, Golestaneh N

The Journal of neuroscience : the official journal of the Society for Neuroscience.. 2013 October 933 (41):16346-59. Epub 1900 01 01.