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John Onukwufor, PhD

John Onukwufor, PhD

Contact

Office (585) 275-1678

About Me

Faculty Appointments

Assistant Professor - Department of Pharmacology and Physiology (SMD)

Publications

Journal Articles

Interactive effects of temperature, cadmium, and hypoxia on rainbow trout (Oncorhynchus mykiss) liver mitochondrial bioenergetics.

Onukwufor JO, Kamunde C

Ecotoxicology and environmental safety.. 2024 December 3289 :117450. Epub 12/03/2024.

Basic Science and Pathogenesis.

Peng W, Osabutey M, Okoye CN, Chung K, Trojanczyk L, Le L, Selim NA, Milliken AS, Al-Qazzaz A, Majewska AK, Wojtovich AP, Dirksen RT, O'Banion MK, Onukwufor JO

Alzheimer's & dementia : the journal of the Alzheimer's Association.. 2024 December 20 Suppl 1 :e090717. Epub 1900 01 01.

DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid ? proteotoxicity.

Peng W, Chung KB, Lawrence BP, O'Banion MK, Dirksen RT, Wojtovich AP, Onukwufor JO

Free radical biology & medicine.. 2024 November 1224 :785-796. Epub 09/22/2024.

DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in amyloid ? proteotoxicity.

Peng W, Chung KB, Lawrence BP, O'Banion MK, Dirksen RT, Wojtovich AP, Onukwufor JO

bioRxiv : the preprint server for biology.. 2024 August 9 Epub 08/09/2024.

Interactive effects of temperature, cadmium, and hypoxia on rainbow trout liver mitochondrial bioenergetics.

Onukwufor JO, Kamunde C

bioRxiv : the preprint server for biology.. 2024 July 16 Epub 07/16/2024.

Epigenetic erosion of H4K20me1 induced by inflammation drives aged stem cell ferroptosis.

Blanc R, Shah N, Salama N, Meng F, Mousaei A, Chakkalakal J, Onukwufor J, Murphy P, Calvi L, Dirksen R

Research square.. 2024 March 15 Epub 03/15/2024.

Osmo-respiratory compromise in the mosshead sculpin (Clinocottus globiceps): effects of temperature, hypoxia, and re-oxygenation on rates of diffusive water flux and oxygen uptake.

Onukwufor JO, Somo DA, Richards JG, Wood CM

Fish physiology and biochemistry.. 2023 October 49 (5):853-866. Epub 08/01/2023.

The Caenorhabditis elegans innexin INX-20 regulates nociceptive behavioral sensitivity.

Chaubey AH, Sojka SE, Onukwufor JO, Ezak MJ, Vandermeulen MD, Bowitch A, Vodi?ková A, Wojtovich AP, Ferkey DM

Genetics.. 2023 April 6223 (4)Epub 1900 01 01.

A reversible mitochondrial complex I thiol switch mediates hypoxic avoidance behavior in C. elegans.

Onukwufor JO, Farooqi MA, Vodi?ková A, Koren SA, Baldzizhar A, Berry BJ, Beutner G, Porter GA, Belousov V, Grossfield A, Wojtovich AP

Nature communications.. 2022 May 313 (1):2403. Epub 05/03/2022.

Iron Dysregulation in Mitochondrial Dysfunction and Alzheimer's Disease.

Onukwufor JO, Dirksen RT, Wojtovich AP

Antioxidants.. 2022 March 3111 (4)Epub 03/31/2022.

Interactive effects of temperature and hypoxia on diffusive water flux and oxygen uptake rate in the tidepool sculpin, Oligocottus maculosus.

Somo DA, Onukwufor JO, Wood CM, Richards JG

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.. 2020 December 250 :110781. Epub 08/05/2020.

Osmorespiratory Compromise in Zebrafish (): Effects of Hypoxia and Acute Thermal Stress on Oxygen Consumption, Diffusive Water Flux, and Sodium Net Loss Rates.

Onukwufor JO, Wood CM

Zebrafish.. 2020 December 17 (6):400-411. Epub 1900 01 01.

Ionoregulatory aspects of the hypoxia-induced osmorespiratory compromise in the euryhaline Atlantic killifish (): the effects of salinity.

Giacomin M, Onukwufor JO, Schulte PM, Wood CM

The Journal of experimental biology.. 2020 July 13223 (Pt 13)Epub 07/13/2020.

Reverse translation: effects of acclimation temperature and acute temperature challenges on oxygen consumption, diffusive water flux, net sodium loss rates, Q values and mass scaling coefficients in the rainbow trout (Oncorhynchus mykiss).

Onukwufor JO, Wood CM

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.. 2020 March 190 (2):205-217. Epub 01/21/2020.

Quantification of reactive oxygen species production by the red fluorescent proteins KillerRed, SuperNova and mCherry.

Onukwufor JO, Trewin AJ, Baran TM, Almast A, Foster TH, Wojtovich AP

Free radical biology & medicine.. 2020 February 1147 :1-7. Epub 12/10/2019.

Physiologic Implications of Reactive Oxygen Species Production by Mitochondrial Complex I Reverse Electron Transport.

Onukwufor JO, Berry BJ, Wojtovich AP

Antioxidants.. 2019 August 68 (8)Epub 08/06/2019.

The osmorespiratory compromise in rainbow trout (Oncorhynchus mykiss): The effects of fish size, hypoxia, temperature and strenuous exercise on gill diffusive water fluxes and sodium net loss rates.

Onukwufor JO, Wood CM

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.. 2018 May 219-220 :10-18. Epub 02/14/2018.

Combined effects of cadmium, temperature and hypoxia-reoxygenation on mitochondrial function in rainbow trout (Oncorhynchus mykiss).

Onukwufor JO, Stevens D, Kamunde C

Aquatic toxicology.. 2017 January 182 :129-141. Epub 11/18/2016.

Hypoxia-reoxygenation differentially alters the thermal sensitivity of complex I basal and maximal mitochondrial oxidative capacity.

Onukwufor JO, Kibenge F, Stevens D, Kamunde C

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.. 2016 November 201 :87-94. Epub 07/04/2016.

Bioenergetic and volume regulatory effects of mitoKATP channel modulators protect against hypoxia-reoxygenation-induced mitochondrial dysfunction.

Onukwufor JO, Stevens D, Kamunde C

The Journal of experimental biology.. 2016 September 1219 (Pt 17):2743-51. Epub 06/29/2016.

Modulation of cadmium-induced mitochondrial dysfunction and volume changes by temperature in rainbow trout (Oncorhynchus mykiss).

Onukwufor JO, Kibenge F, Stevens D, Kamunde C

Aquatic toxicology.. 2015 January 158 :75-87. Epub 11/13/2014.

Effects of hypoxia-cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia-induced proton leak by low doses of cadmium.

Onukwufor JO, MacDonald N, Kibenge F, Stevens D, Kamunde C

The Journal of experimental biology.. 2014 March 15217 (Pt 6):831-40. Epub 11/21/2013.