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Hae-Ryung Park, M.S., Ph.D.

Hae-Ryung Park, M.S., Ph.D.

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Office (585) 276-3937

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About Me

Faculty Appointments

Assistant Professor - Department of Environmental Medicine (SMD)

Credentials

Education

PhD | University of Michigan. Toxicology. 2014

MS | Korea-Yonsei University. Biotechnology. 2010

BS | Korea-Yonsei University. Biotechnology. 2007

Awards

Best Poster Presentation Award. 2019

K99/R00 Pathway to Independence Award. 2019

Dr. Donald Hornig Postdoctoral Fellow Award. 2019

KTAA Best Poster Presentation. 2018

Best Poster Presentation Award. 2018

Jere Mead Endowment Fellowship. 2017 - 2018

Best Poster Presentation Award. 2016

Rackham One Term Dissertation Fellowship. 2014

Graduate Student Travel Award. 2013

Rackham Centennial Award. 2013

Rackham Graduate Student Research Grant. 2013

Young Soo Choi Scholarship. 2012

Departmental Scholarship. 2011

Scholarship for Excellent Student. 2008 - 2010

Brain Korea 21 Participation Scholarship. 2008 - 2010

Graduated with High Honors. 2007

Scholarship for Excellent Student. 2003 - 2007

National Science and Technology Scholarship. 2003 - 2007

Scholarship from Yonsei Honors Society.

Research

Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism ...
Identify new targets susceptible to environmental perturbation in relevance with neurodevelopment or neurodegenerative diseases by utilizing functional genetics/genomics (RNAi and CRISPR screens and Next-Generation sequencing), and molecular benchwork. Discover the link between genetic polymorphism of the targets and neurological diseases. Explore novel roles of extracellular vesicles (EV) in receptor signaling and cell communication. Identify EV-encapsulated biomolecules released by the placenta in response to environmental perturbation. Explore the roles of placenta-derived EVs on neurodevelopment or neurodegeneration

Publications

Journal Articles

Arrestin domain-containing protein 1-mediated microvesicles (ARMMs) protect against cadmium-induced neurotoxicity.

Chen Z, Qiao Z, Wirth CR, Park HR, Lu Q

Extracellular vesicle.. 2023 December 2 Epub 07/14/2023.

MicroRNA-124 Reduces Arsenic-induced Endoplasmic Reticulum Stress and Neurotoxicity and is Linked with Neurodevelopment in Children.

Park HR, Sun R, Panganiban RA, Christiani DC, Lu Q

Scientific reports.. 2020 April 310 (1):5934. Epub 04/03/2020.

Brominated diphenyl ether-47 differentially regulates cellular migration and invasion in a human first trimester trophoblast cell line.

Park HR, Elkin ER, Castillo-Castrejon M, Loch-Caruso R

Reproductive toxicology.. 2020 April 93 :191-198. Epub 03/03/2020.

Genome-wide CRISPR screen identifies suppressors of endoplasmic reticulum stress-induced apoptosis.

Panganiban RA, Park HR, Sun M, Shumyatcher M, Himes BE, Lu Q

Proceedings of the National Academy of Sciences of the United States of America.. 2019 July 2116 (27):13384-13393. Epub 06/18/2019.

Transcriptomic response of primary human airway epithelial cells to flavoring chemicals in electronic cigarettes.

Park HR, O'Sullivan M, Vallarino J, Shumyatcher M, Himes BE, Park JA, Christiani DC, Allen J, Lu Q

Scientific reports.. 2019 February 19 (1):1400. Epub 02/01/2019.

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q

The Journal of allergy and clinical immunology.. 2018 November 142 (5):1469-1478.e2. Epub 01/09/2018.

Group B streptococcus activates transcriptomic pathways related to premature birth in human extraplacental membranes in vitro.

Park HR, Harris SM, Boldenow E, McEachin RC, Sartor M, Chames M, Loch-Caruso R

Biology of reproduction.. 2018 March 198 (3):396-407. Epub 1900 01 01.

Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children.

Wagner PJ, Park HR, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q

Environmental health perspectives.. 2017 April 125 (4):721-729. Epub 08/26/2016.

New Insights Into Cellular Stress Responses to Environmental Metal Toxicants.

Park HR, Oh R, Wagner P, Panganiban R, Lu Q

International review of cell and molecular biology.. 2017 331 :55-82. Epub 11/30/2016.

Reactive Oxygen Stimulation of Interleukin-6 Release in the Human Trophoblast Cell Line HTR-8/SVneo by the Trichlorethylene Metabolite S-(1,2-Dichloro)-l-Cysteine.

Hassan I, Kumar AM, Park HR, Lash LH, Loch-Caruso R

Biology of reproduction.. 2016 September 95 (3):66. Epub 08/03/2016.

Protective effect of (±)?-tocopherol on brominated diphenyl ether-47-stimulated prostaglandin pathways in human extravillous trophoblasts in vitro.

Park HR, Loch-Caruso R

Toxicology in vitro : an international journal published in association with BIBRA.. 2015 October 29 (7):1309-18. Epub 05/27/2015.

Tetrabromobisphenol A activates inflammatory pathways in human first trimester extravillous trophoblasts in vitro.

Park HR, Kamau PW, Korte C, Loch-Caruso R

Reproductive toxicology.. 2014 December 50 :154-62. Epub 10/17/2014.

Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line.

Park HR, Loch-Caruso R

Toxicology and applied pharmacology.. 2014 November 15281 (1):67-77. Epub 10/11/2014.

Involvement of reactive oxygen species in brominated diphenyl ether-47-induced inflammatory cytokine release from human extravillous trophoblasts in vitro.

Park HR, Kamau PW, Loch-Caruso R

Toxicology and applied pharmacology.. 2014 January 15274 (2):283-92. Epub 12/01/2013.

?-Glycosidase-assisted bioconversion of ginsenosides in purified crude saponin and extracts from red ginseng (Panax ginseng C. A. Meyer)

Park, HR; Ghafoor, K; Lee, D; Kim, S; Kim, SH; Park, J.

Food Science and Biotechnology. 2013; 22(6): 1629-1638.

Effects of the beta-glycosidase reaction on bio-conversion of isoflavones and quality during tofu processing.

Ryu YG, Won B, Park HR, Ghafoor K, Park J

Journal of the science of food and agriculture.. 2010 April 1590 (5):843-9. Epub 1900 01 01.