A clinical trial is a research study involving human volunteers, and is designed to answer specific health questions. Carefully conducted clinical trials are the safest and fastest way to find effective treatments, and new ways to improve health.
You can search for all studies that are currently enrolling participants at the University of Rochester by typing in keywords in the search box below. If you don’t find a study that interests you right now, consider signing up for our Volunteer Registry, which will notify you of future studies.
*RTOG 1216 / RHAN13055 / Surgery and Postoperative Radiation / Yuhchyau Chen
Lead Researcher: Yuhchyau Chen
This phase II/III trial studies how well radiation therapy works when given together
with cisplatin, docetaxel, cetuximab, and/or atezolizumab after surgery in treating
patients with high-risk stage III-IV head and neck cancer the begins in the thin,
flat cells (squamous cell). Specialized radiation therapy that delivers a high dose
of radiation directly to the tumor may kill more tumor cells and cause less damage
to normal tissue. Drugs used in chemotherapy, such as cisplatin and docetaxel, work
in different ways to stop the growth of tumor cells, either by killing the cells or
by stopping them from dividing. Cetuximab is a monoclonal antibody that may interfere
with the ability of tumor cells to grow and spread. Immunotherapy with monoclonal
antibodies, such as atezolizumab, may help the body's immune system attack the cancer,
and may interfere with the ability of tumor cells to grow and spread. The purpose
of this study is to compare the usual treatment (radiation therapy with cisplatin
chemotherapy) to using radiation therapy with docetaxel and cetuximab chemotherapy,
and using the usual treatment plus an immunotherapy drug, atezolizumab.
View Study Details
Adapting CBT-I for Hazardous Alcohol Users
Lead Researcher: Wilfred Pigeon
The goal of this intervention development trial is to develop, refine, and test a
telephone-delivered, 4-session version of cognitive behavioral therapy for insomnia
adapted
to hazardous alcohol users with co-occurring insomnia. The project will begin with
a small,
open label pilot to refine the intervention and proceed to a small, randomized trial
comparing the intervention to a sleep and alcohol education control condition.
The two main questions it aims to answer are whether the intervention is feasible
to deliver
and whether its effects on alcohol use and insomnia severity are large enough to warrant
further work.
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BEGIN - A Breastfeeding Study
Lead Researcher: Bridget Young
We are looking for:
- Mothers who are exclusively pumping for babies under 5 weeks old
- Participation will last until your baby is 5 months old
- We will have you collect breastmilk, stool, urine, and saliva at home
- This study is totally remote – no need to ever leave your house!
Earn $100/month & receive breastfeeding support from our team!
View Study Details
CMMY19113 / S1803 / Brea Lipe
Lead Researcher: Brea Lipe
Patients are enrolled to screening (Reg Step 1) prior to or after ASCT but prior to
Reg Step 2. Patients are followed until they will begin Maintenance and then registered
to Reg Step 2 (first randomization). Patients are randomized between Lenalidomide
for 2 years and Lenalidomide + Daratumumab/rHuPH20. After 2 years of Maintenance,
MRD is assessed to guide further therapy. MRD-positive patients will continue with
the assigned treatment. MRD-negative patients will be further randomized (Reg Step
3) to either continue or discontinue the assigned treatment. Patients are treated
for up to 7 years from Step 2 reg and followed for up to 15 years.
View Study Details
Connection in Caregivers
Lead Researcher: Kimberly Van orden
Subjects will complete a baseline interview (phone/zoom and online) at the beginning
of the study. If eligible, subjects will complete 10 days of surveys that are texted
3 times a day (morning, afternoon, evening). Eligible subjects will also complete
a follow-up interview (zoom/phone and online) at 6 months. Subjects are paid up to
$400 for completing assessments. Inclusion: age 50 and older; caring daily for a
loved one with dementia; caregiving stress. Exclusion: Under 50 years of age; not
caring for a loved one with dementia daily.
View Study Details
Interactive Group Drumming and "Chemo Brain"
Lead Researcher: Gaelen Mccormick
If you decide to take part in this study, you will be asked to participate, as you
are able,
in four consecutive weekly drumming groups of up to ten people occurring at the same
time each week, led by a professional facilitator. Each group will be one hour in
length. During these groups, the facilitator will invite subjects to follow simple
oral (singing and speaking) and musical instructions by playing the drums we will
provide.
At the beginning and the end of each session, you will be asked to answer a brief
questionnaire about your state of wellbeing. At the beginning and end of the study,
you will be asked to answer a survey about cognitive function (and your experience
with “chemo brain”) using the FACT COG assessment survey. After the study concludes,
you will be asked to answer a survey about satisfaction with your experience of the
drumming session. Your participation will last about 4 weeks.
View Study Details