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Observational Study of ICU Patients with Systemic Inflammatory Response Syndrome (SIRS)

Research Question:
Do patients with different causes of severe Systemic Inflammatory Response Syndrome (SIRS) have similar or different severity of illness and recovery rates? What are the biological similarities and differences between patients with severe SIRS caused by different illnesses? Will the biological tests we do in this study help us to predict how sick patients will become and how their health will be after the severe SIRS is over?

Basic Study Information

Purpose:
This is an observational research study of subjects admitted to the ICU with severe SIRS (and/or sepsis). For ICU subjects enrolled: the study involves collecting up to 2 blood samples (3-5 days apart), data collection, and post-discharge follow-up questionnaires. For healthy volunteers: Subjects age 65 and older are needed for a one-time blood sample collection for comparison studies. A brief health questionnaire and set of vital signs will also be collected at the study visit. Volunteers must be age 65 or older and cannot be on antibiotics or antivirals for current infection. Volunteers also must not have had an infection within 6 weeks prior to the study visit.

Location: Pulmonary & Critical Care
Study Reference #: 204

Lead Researcher (Principal Investigator)

Lead Researcher:  Anthony Pietropaoli

Study Contact Information

Study Coordinator: Amy Rovitelli
Phone: (585) 274-1003
Email: Amy_Rovitelli@urmc.rochester.edu

Additional Study Details

Study Details:
Healthy volunteer subjects age 65 or older who meet study entry criteria will have a one-time visit that takes about 15-20 minutes. A stipend of $20 is provided for your time and parking pass also provided.

Number of Visits:  1
Parking:  Free
Transportation Coverage:  No
Reimbursement:  No

Learn More About These Conditions

More information about Sepsis

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