URMC / Research / Mass Spectrometry Resource Lab / Services Services Consultation Research project design and planning Proper sample preparation for subsequent MS-based analysis Assistance with data interpretation, grant writing, and publication Sample Preparation Sample clean-up and processing: Proteolytic digest Lysis BCA to determine protein concentration Desalting SDS-PAGE gel electrophoresis and staining Mass Spectrometry Protein and peptide identification in purified samples or complex mixtures Protein Quantitation Small molecule quantitation PTM identification Data Analysis Proteome Discoverer data analysis software, including CHIMERYS and SEQUEST search algorithms, for Data Dependend Acquisition analysis DIA-NN for Data Independent Acquistion analysis LC-Quan software for small molecule quantitation